Clinical trials: Tourniquet
Hand Injuries/Disease Requiring Surgery to the Hand
A Study Investigating Ways to Make Local Anaesthetic Hand Surgery Less Painful - Reducing Tourniquet Associated Pain
Hand surgery requires a reduced blood flow to the hand during the operation, which is achieved using a tourniquet (tightly inflated circumferential cuff) around the upper arm. However this tourniquet is painful.
- Trial name
- ReTAP (NCT01611064)
- Testing
- Oxygen, Medical air
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Osteoarthritis of the Knee
Clinical and Stereoradiological Comparison of the Results After Primary Cemented Total Knee Arthroplasty Inserted With or Without the Use of a Tourniquet
The purpose of this study is to investigate if the use of a tourniquet during insertion of a cemented primary total knee arthroplasty will influence clinical and radiological (measured with RSA X-ray technique) outcome.
- Trial name
- NCT01488175
- Testing
- tourniquet, no tourniquet
- Where
- Denmark
- Sponsor
- Hvidovre University Hospital
Ischemia
Optimal Time Delay of Epinephrine Injection With "One-per-mil" Tumescent Solution
The aim of this study is to know the characteristic of "one-per-mil" tumescent solution in regards of the optimal time delay to achieve optimal visualization of operation field in hand and digit surgery. Hypothesis: 1.
- Trial name
- NCT02033681
- Testing
- "One-per-mil" Tumescent Solution Injection, Saline Solution
- Where
- Indonesia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Pregnancy, Placenta Accrete Spectrum
Impact Tourniquet Conservative Placenta Accreta Neonatal APGAR
Placenta accreta spectrum disorder (PAS) refers to a condition where the placenta fails to separate naturally after childbirth, which can cause significant maternal and neonatal complications, including severe bleeding, leading…
- Conditions
- Pregnancy, Placenta Accrete Spectrum, Tourniquets, Apgar Score
- Trial name
- NCT07412925
- Testing
- Application Of A Tourniquet Around the lower segment of the uterus, Placenta Accreta spectrum conservative management
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Kasr El Aini Hospital
Osteoarthritis
Evaluation of Short-term Effects of Tourniquet Use in Different Ways During Total Knee Arthroplasty
To study the short-term effects of tourniquet use in different ways in total knee arthroplasty,60 patients were randomly divided into 2 groups (30 cases/group): group A using the tourniquet throughout the operation, and group B…
- Trial name
- NCT02102581
- Testing
- short time tourniquet
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Primary Gonarthrosis
Effects of Tourniquet Applied During Total Knee Replacement Surgery on Patient Hemodynamics and Blood Table
This study was planned to investigate the physiopathology of bradycardia and hypotension that occur in some patients with total knee arthroplasty (TKA) between the ages of 65 and 90 years when the tourniquet, which is routinely…
- Trial name
- NCT07002086
- Testing
- Total knee replacement
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Extremity Injury
Pre-hospital Tourniquet in Extremity Injury
2.1. Objective: Primary Objective: To compare outcomes of patients with extremity injuries presenting with or without pre-hospital tourniquet placement. 2.2.
- Trial name
- NCT04216225
- Testing
- pre-hospital tourniquet placement
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Methodist Health System
Distal Radius Fracture
Surgical Field Quality Assessment and Complications in Distal Radius Fractures Using the Minimum Inflation Tourniquet Pressure.
Analyse surgical field bleeding, surgical time, and intraoperative pain in patients undergoing osteosynthesis of distal radius fractures using ischaemia pressure calculated based on Limb Occlusion Pressure, compared with Arterial…
- Trial name
- NCT07318194
- Testing
- PNEUMATIC TOURNIQUET INFLATION PRESSURE
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Consorci Sanitari de Terrassa
Tourniquet Safety and Effectiveness
A New Technique for Determining Limb Occlusion Pressure
This study evaluates a novel technique for measuring the minimum pressure necessary to achieve a bloodless surgical field, known as a patient's limb occlusion pressure (LOP).
- Trial name
- NCT02620722
- Testing
- Personalized Tourniquet Instrument, Handheld Doppler ultrasound
- Where
- 4 sites in Canada
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Hemorrhage, Hypovolemic Shock
Efficacy of Prehospital Tourniquet Models for Arterial Occlusion in Upper and Lower Limbs
The goal of this clinical trial is to compare the occlusive capability and mechanical behavior of different commercially available pre-hospital tourniquet models and the results of their application on upper and lower limbs, in…
- Conditions
- Hemorrhage, Hypovolemic Shock, Tourniquets
- Trial name
- TQ-BR (NCT06725602)
- Testing
- TQ - Proximal Application ("high and tight"), TQ - Controlled application (2-3 inches)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Blood Pressure
Tourniquets Increase Proximal Pressure
There is an urgent clinical need to improve survival and neurologic outcomes after cardiac arrest. When a patient goes into cardiac arrest, cardiopulmonary resuscitation (CPR) with chest compressions is the current standard of…
- Trial name
- NCT05324306
- Testing
- combat application tourniquets (CAT)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Blood Loss
The Effects of Tourniquet Use in Total Knee Arthroplasty
Tourniquets are still widely used in total knee arthroplasty, but are associated with several adverse effects. Most of previous studies did not randomize the participants so the baseline difference of the patients might have…
- Trial name
- NCT02429713
- Testing
- Short-duration tourniquet, Long-duration tourniquet
- Volunteers
- 50 people
- Sponsor
- Peking University People's Hospital
Postpartum Haemorrhage (PPH)
Temporary Aortic Occlusion With the Abdominal Tourniquet for Refractory Postpartum Haemorrhage: A Proof-of-Concept Study in a War-Affected Region
The purpose of this study is to evaluate whether a medical device called the Abdominal Aortic and Junctional Tourniquet - Stabilized (AAJT-S) can safely and effectively temporarily stop severe bleeding after childbirth (known as…
- Trial name
- TAOAT (NCT07016568)
- Testing
- Abdominal Aortic and Junctional Tourniquet - Stabilized (AAJT-S)
- Where
- Ukraine
- Volunteers
- 4 people
- Sponsor
- LLC UkrMedGroup
Hemorrhage
Performance of Junctional Tourniquets in Normal Human Volunteers
Normal human adult volunteers wereused to investigate the performance of medical devices intended to stop junctional bleeding on the battlefield.
- Trial name
- NCT01965561
- Testing
- CRoC, AAJT, JETT
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- United States Army Institute of Surgical Research
Limb Occlusion Pressure
Limb Occlusion Pressure Tourniquets to Decrease Pain After Surgery
Currently a standard tourniquet pressure is used for orthopedic surgeries. High tourniquet pressure had been associated with adverse side effects such as ischemia, muscle weakness, and post operative pain.
- Trial name
- LOP (NCT04390425)
- Testing
- Experimental - Limb Occlusion pressure
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Uterine Myoma
Single or Triple Uterine Tourniquet at Myomectomy
The aim of study is to compare triple tourniquet vs. single tourniquet to reduce blood loss at open myomectomy.
- Trial name
- NCT02392585
- Testing
- Single tourniquet, Triple tourniquet
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ragıp Atakan Al
Arteriovenous Fistula, Tourniquet
Brachiocephalic Arteriovenous Fistulae: Two Different Techniques of Bloodless Surgery and Their Effect on Fistula Stenosis.
Patients with a chronic kidney disease who opt for hemodialysis, needs a well-functioning hemodialysis access. The autologous arteriovenous fistula (AVF) is recognized as the golden standard of dialysis access.
- Conditions
- Arteriovenous Fistula, Tourniquet, Stenosis
- Trial name
- ABAS (NCT04402775)
- Testing
- Tourniquet
- Volunteers
- 25 people
- Sponsor
- HagaZiekenhuis
Orthopedic Disorder, Hemodynamic Instability
Evaluating The Cardiovascular Effects of Tourniquet Application
The goal of this prospective observational study is to investigate the impact of tourniquet application on cardiac efficiency through the cardiac cycle efficiency parameter and to explore how central regional technique alters…
- Trial name
- NCT06158165
- Testing
- Mostcare (Vytech, Vygon, Padua, Italy)
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Merve Şeker
Vascular Diseases
Two Mathematical Methods to Estimate Arterial Occlusion Pressure and Tourniquet Effectiveness in Lower Limb Surgery
Pneumatic tourniquets are widely used not only to reduce blood loss and to ensure optimal operating conditions during extremity surgery, but also in regional anesthesia (local intravenous) vein puncture and to control life or…
- Trial name
- NCT03706859
- Testing
- Pneumatic tourniquet inflation pressure
- Where
- Egypt
- Volunteers
- 77 people
- Sponsor
- Beni-Suef University
Chronic Ankle Instability, Ankle Ligament Injury
Dilute Epinephrine vs Tourniquet for Visualization in Ankle Arthroscopy: A RCT
This multicenter, prospective randomized controlled trial investigates the effect of dilute epinephrine irrigation versus tourniquet use on visual field clarity (VFC) during ankle arthroscopy.
- Conditions
- Chronic Ankle Instability, Ankle Ligament Injury, Ankle Arthroscopy
- Trial name
- NCT07349407
- Testing
- Epinephrine group, Tourniquet group
- Volunteers
- 88 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine