Clinical trials: Trace Elements, open to volunteers
Pregnancy Related
Multiple Micronutrient Supplementation (MMS) vs IFA Acceptability Crossover Trial
This is an open-label individually randomized mixed methods cross-over trial to assess acceptability, preference, and side effects of IFA formulations with 60 mg of iron to MMS formulations with 60 mg of iron.
- Trial name
- MIFA-ACT (NCT06069856)
- Testing
- Iron Folic Acid Tablets with 60 mg of iron, Multiple Micronutrient Supplements with 60 mg of elemental iron
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- George Washington University
Pregnancy
Iron Absorption From IFA and MMS Supplements in Kenyan Women During the Second Trimester of Pregnancy
This study evaluates iron absorption from three antenatal supplements, 30 mg MMS, 60 mg MMS, and 60 mg IFA, in 50 pregnant Kenyan women in their second trimester.
- Trial name
- PROUD (NCT07435766)
- Testing
- MMS with 30 mg iron, MMS with 60 mg iron, IFA with 60 mg iron
- Where
- 2 sites in Kenya
- Volunteers
- 50 people
- Sponsor
- ETH Zurich
Nutritional Status, Omega 3 Fat Status
Association of Seafood Consumption and Nutritional Status Among Adolescent Girls
This study examines how seafood consumption, social changes, and climate change affect the nutrition and well-being of adolescent girls in south-western Bangladesh.
- Conditions
- Nutritional Status, Omega 3 Fat Status, Micronutrient Status, Fish Consumption
- Trial name
- AQUAFOOD (NCT07555197)
- Testing
- Assess natural behavior
- Where
- Bangladesh
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Nutritional Status, Nutrient Deficiency
Challenges in Achieving Adequate Dietary Status of Women
The aim of the study is to investigate the dietary habits of women of reproductive age (20-49 years). We aim to obtain epidemiological data on the intake and adequacy of key macronutrients and micronutrients, as well as to…
- Conditions
- Nutritional Status, Nutrient Deficiency, Micronutrient Deficiency, Vitamin D Deficiency
- Trial name
- NutriFem (NCT06745817)
- Testing
- Assessement of nutritional status, Dermis density and thickness, Skin elasticity
- Where
- 3 sites in Slovenia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Neurocognition, Child
Early Life Thiamine Study
Thiamine (vitamin B1) is an important nutrient needed for energy metabolism, brain development, and overall health. However, low thiamine intake is a concern in countries where white rice is the main staple since it contains…
- Trial name
- NCT07795996
- Testing
- Multiple micronutrient supplementation
- Where
- Cambodia
- Volunteers
- 1,972 people
- Sponsor
- Mount Saint Vincent University
Birth Weight
Healthy Mums, Healthy Babies: Multiple Micronutrient Supplementation in Ethiopia
Background: This programme effectiveness study responds to the need for evidence on the effect on birthweight of switching from iron-folic acid supplementation (IFA) to multiple micronutrient supplementation (MMS) as part of…
- Trial name
- NCT05708183
- Testing
- Multiple micronutrient supplementation (MMS), Iron folate supplementation (IFA)
- Where
- 6 sites in Ethiopia
- Volunteers
- 25,620 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Obesity, Blood Glucose, High
A Culturally-relevant Micronutrient-dense Plant-rich (mNDPR) Dietary Intervention for Native Americans
The investigators propose to conduct a randomized controlled trial with a wait-list control to determine efficacy in reducing risk of obesity and related disease in Native American employees of Twin Arrows Casino.
- Trial name
- NCT04755062
- Testing
- Micronutrient-dense plant-rich Intervention
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Trace Element Deficiency
Determination of Copper and Other Trace Elements in Serum Samples From Patients With Biliary Tract Cancers
The aim of the study is to determine the total concentration of selected trace elements (Cu, Zn, Fe), the proportion of free Cu and Cu bound to ceruloplasmin and the isotopic ratio of Cu65/Cu63 in blood serum samples from healthy…
- Trial name
- NCT06060990
- Testing
- trace elements
- Where
- Slovenia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institute of Oncology Ljubljana
Iodine Deficiency, Nutrition Poor
Effects of Maternal Multiple Micronutrient Supplementation During Lactation on Child Development in Ethiopia
The goal of this clinical trial is to learn about the effects of iodine-containing multiple micronutrient supplements provided to breastfeeding mothers who live in settings with mild iodine deficiency.
- Conditions
- Iodine Deficiency, Nutrition Poor, Development, Infant, Breastfeeding
- Trial name
- EMECHAT (NCT05901766)
- Testing
- UNIMMAP Multiple Micronutrient Supplement
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Brown University
Newborn Health, Multiple Micronutrient Deficiencies During Pregnancy
The MOM-CARE Trial : Evaluating Antenatal and Postnatal MMSPlus for Improved Infant Birth and Growth Outcomes
This clinical trial aims to learn if MMS Plus improves infant health compared to standard MMS during pregnancy and the postnatal period in women living in peri-urban areas of Karachi, Pakistan.
- Conditions
- Newborn Health, Multiple Micronutrient Deficiencies During Pregnancy, Nutrition During Pregnancy, Adaptive Trial
- Trial name
- MOM-CARE (NCT07029282)
- Testing
- MMS, MMS Plus, IFA
- Where
- Pakistan
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Malnutrition Pregnancy, Malnutrition in Children
Early Life Malnutrition, Environmental Enteric Dysfunction and Microbiome Trajectories
Malnutrition in women of reproductive age remains a public health concern in Sub-Saharan Africa (SSA). Malnutrition during pregnancy affects foetal growth with a tendency of the exposed infants to also develop it.
- Conditions
- Malnutrition Pregnancy, Malnutrition in Children, Malnutrition (Calorie), Environmental Enteric Dysfunction
- Trial name
- UZBCS-2 (NCT07195006)
- Testing
- Malnutrition in pregnancy as exposure, Poor WASH living conditions as exposure
- Where
- Zimbabwe
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- University of Zimbabwe
Anemia, Iron Deficiency
Co-administration of Calcium and Multiple Micronutrient Supplements for Maternal and Newborn Hemoglobin and Iron Status
The World Health Organization (WHO) currently recommends the pregnant women receive iron-containing supplements and, in settings where calcium intake is low, calcium supplements.
- Trial name
- CaMMS (NCT06568315)
- Testing
- Concurrent multiple micronutrient and calcium supplementation, Separate multiple micronutrient and calcium supplementation
- Where
- 2 sites in Burkina Faso, Pakistan
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Pregnancy Related
Multiple Micronutrient Supplementation for Maternal Anemia Prevention in Tanzania
This is an individually randomized controlled trial to assess the effect of multiple micronutrient supplements (MMS) containing 60 and 45 mg iron as compared to MMS containing 30 mg of iron (standard UNIMMAP formulation) on…
- Trial name
- MMS-MAP (NCT06079918)
- Testing
- Multiple Micronutrient Supplements with 30 mg of elemental iron, Multiple Micronutrient Supplements with 45 mg of elemental iron, Multiple Micronutrient Supplements with 60 mg of elemental iron
- Where
- Tanzania
- Volunteers
- 6,381 people, healthy volunteers welcome
- Sponsor
- George Washington University
Pregnancy, Adherence
A Study of Multiple Micronutrient Supplementation (MMS) to Increase Adherence With Digital Technology
The goal of this randomized clinical trial is to learn whether a digital health intervention can improve adherence to Multiple Micronutrient Supplementation (MMS) among pregnant women in Lombok Island.
- Trial name
- SMART-MMS (NCT07555093)
- Testing
- Bottle pack, Blister pack, Standard Care
- Where
- Indonesia
- Volunteers
- 10,012 people, healthy volunteers welcome
- Sponsor
- Summit Institute for Development, Indonesia
Micronutrient Status
Bioavailability of Micronutrients With a Special Focus on Vitamin K Dependent on Consumed Diet
Objectives The main objectives are: Study part II: to investigate the effect of a plant-based diet on micronutrient status compared to an average Danish diet Hypotheses Study part II: it is hypothesised that the status of some…
- Trial name
- BioMicro (NCT06921018)
- Testing
- change in diet
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Ulcerative Colitis (UC)
The Efficacy of Lactobacillous Probiotic and Trace Elements in the Management of Ulcerative Colitis Patients the Patients Will be Recruited From Outpatient Clinic of Inflammatory Bowel Disease (IBD) of the National Hepatology and Tropical Medicine Research Institute NHTMRI, Cairo, Egypt
the goal of this interventional observational study is to To evaluate the efficacy , safety of lactobacillus probiotics or trace elements when added to (ulcerative colitis) infliximab in maintaining remission in UC patients and…
- Trial name
- NCT07758335
- Testing
- Lactobacillus acidophilus will be assigned for arm 1, trace elements, Control Arm - standard of care
- Where
- Egypt
- Volunteers
- 132 people
- Sponsor
- National Hepatology & Tropical Medicine Research Institute
Good Responders According to Guidelines Who Wre Charectarized by AMH>0.8ng/dl, Trace Elements in ICSI Cases
Evaluation of Some Trace Elements in Follicular Fluid in ICSI Cases and Their Effect on ICSI Outcomes
To evaluate concentrations of some trace elements in the follicular fluid and their reproductive outcomes.
- Trial name
- ICSI (NCT06719817)
- Where
- 2 sites in Egypt
- Volunteers
- 154 people
- Sponsor
- Assiut University
Total Hip Arthroplasty (THA), Total Knee Arthroplasty (TKA)
Molecular Mechanisms Underlying Hip and Knee Osteoarthritis in Patients Undergoing Primary Elective Arthroplasty
The aim of this observational study is to determine content of rare metals and other elements, along with the levels of selected immunological parameters, in the tissue of the hip or knee joint in the course of degenerative…
- Conditions
- Total Hip Arthroplasty (THA), Total Knee Arthroplasty (TKA), Hip Osteoarthritis, Knee Osteoarthristis
- Trial name
- NCT07347821
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- Medical University of Warsaw
Weight Loss, Nutritional Deficiencies
Multivitamin Impact on Micronutrient Status in GLP-1 Users: A Randomized Trial
Rationale: Glucagon-Like Peptide-1 (GLP-1) receptor agonists have emerged as effective treatments for obesity and associated medical conditions.
- Conditions
- Weight Loss, Nutritional Deficiencies, GLP - 1, Obese Patients
- Trial name
- VITAGLP (NCT07234916)
- Testing
- Multivitamin Supplementation
- Where
- 2 sites in Netherlands
- Volunteers
- 246 people
- Sponsor
- Erasmus Medical Center
Bariatric Surgery, Pregnency
Mother and Offspring's Nutritional Status -Pregnancy After Maternal Bariatric Surgery
The goal of this observational study is to learn how bariatric surgery affects the health and nutritional status of women and their babies during pregnancy and after birth.
- Conditions
- Bariatric Surgery, Pregnency, Reproductive Health and Childbirth, Pregnancy and Delivery
- Trial name
- MOBS (NCT07877233)
- Testing
- Post-Bariatric Maternal and Infant Health Study, Observation arm
- Where
- 3 sites in Norway
- Volunteers
- 210 people
- Sponsor
- Helse Nord-Trøndelag HF