Clinical trials: Tracheal Diseases
Urachal Cancer, Parathyroid Carcinoma
Agnostic Therapy in Rare Solid Tumors
The ANTARES study is a phase II basket trial designed to evaluate the tissue-agnostic efficacy of the monoclonal anti-PD1 antibody, nivolumab, in patients with advanced or metastatic rare tumors.
- Conditions
- Urachal Cancer, Parathyroid Carcinoma, Fibrolamellar Carcinoma, Angiosarcoma
- Trial name
- ANTARES (NCT06638931)
- Testing
- Nivolumab
- Where
- 5 sites in Brazil
- Volunteers
- 28 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Dysphagia
TTE and Dysphagia in Anterior Cervical Surgery
The purpose of this study is to evaluate if Tracheal Traction Exercises (TTE) performed prior to anterior cervical spine surgery can result in a decreased rate of dysphagia.
- Trial name
- NCT02326116
- Testing
- Trachael Preparation Education
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Rochester
Injury of Trachea, Friction and Pressure Injuries
The Ornge Comparison of Tracheal Occlusion Pressures to Ensure Safety Trial
Patients who are intubated (breathing tube in windpipe) are often transported by air ambulance. Changes in atmospheric pressure during flight may cause pressure increases in the air-filled cuff holding the tube in the windpipe.
- Conditions
- Injury of Trachea, Friction and Pressure Injuries, Barotrauma, Transfer/Transport Injury
- Trial name
- OCTOPUS (NCT01384500)
- Testing
- Saline in tube cuff
- Where
- Canada
- Sponsor
- Ornge Transport Medicine
Tracheomalacia, Tracheal Stenosis
A Study to Assess the Safety, Tolerability and Potential Efficacy of a Tracheal Replacement Consisting of a Tissue-engineered Tracheal Scaffold With Seeded Mesenchymal Cells
This is a phase I study to evaluate the safety, efficacy and tolerability of a novel tracheal replacement therapy using cadaveric de-cellularised tracheal scaffold and patients' own mesenchymal cells isolated from a sample of…
- Trial name
- NCT02949414
- Testing
- Cadaveric decellularised tracheal scaffold seeded with autologous mesenchymal cells
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- Cell Therapy Catapult
Anesthesia Intubation Complication, Intubation Complication
A Comparison Of Local Anesthetic Agents And Steroid On Tracheal Tube Cuff
This study aims to compare effects of two different agents on complications due to tracheal tube cuff in pediatric patients. Sore throat, hoarseness, laryngospasm, bronchospasm are the main complications.
- Conditions
- Anesthesia Intubation Complication, Intubation Complication, Sore Throat
- Trial name
- LA-STEROID (NCT04085744)
- Testing
- Lidocaine 10% Spray, Mometasone nasal spray
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Derince Training and Research Hospital
Non-small Cell Lung Cancer, Lung Function Decreased
Effects of Nonintubated Thoracoscopic Lobectomy on Lung Protection
A novel nonintubated thoracoscopic technique is promising to enhance recovery after thoracic surgery. However, the effects of nonintubated technique on specific organ protection in not clear yet.
- Conditions
- Non-small Cell Lung Cancer, Lung Function Decreased, Tracheal Intubation Morbidity
- Trial name
- NCT03471884
- Testing
- Nonintubated thoracoscopic lobectomy, Intubated thoracoscopic lobectomy
- Where
- Taiwan
- Volunteers
- 82 people
- Sponsor
- National Taiwan University Hospital
Covid19, ARDS
Noninvasive Ventilation in Moderate-to-severe COVID-19-associated Acute Respiratory Distress-syndrome
Non-invasive ventilation can allow to avoid intubation and improve outcomes in moderate-to-severe COVID-19-associated acute respiratory distress-syndrome (ARDS).
- Trial name
- COVID-NIV (NCT04667923)
- Testing
- Respiratory monitoring, Respiratory muscles ultrasound, Electro impedance tomography
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Endotracheal Intubation, Obesity
A Comparison of Tracheal Intubation Using the Totaltrack vs the Macintosh Laryngoscope in Obese Patients
Airway management in obese patients has to consider that mask ventilation (DMV) risk is increased and difficult tracheal intubation (DTI) risk may be increased too.
- Conditions
- Endotracheal Intubation, Obesity, Desaturation, Ventilation
- Trial name
- Ovesion (NCT03106974)
- Testing
- orotracheal intubation Macintosh Laryngoscope, orotracheal intubation Totaltrack VLM
- Where
- Spain
- Volunteers
- 1,440 people
- Sponsor
- AnestesiaR