Clinical trials: Tracheostomized Patients
Resp Gas Exchange Disorder Nos
Effect of Parallel Oxygen Delivery Through a Tracheal Gas Insufflation (TGI) and a T-piece, on Blood Gases and Respiratory Rate, in ICU Tracheostomized Patients
The study investigates if there are benefits (better oxygenation, minimized work of breath) from the parallel oxygenation with Tracheal Gas Insufflation and T-piece, in order to provide respiratory support in tracheostomized…
- Trial name
- NCT03040297
- Testing
- Tracheal gas insufflation 6 L/min, Tracheal gas insufflation 11 L/min, Tracheal gas insufflation catheter, without gas flow
- Where
- Greece
- Volunteers
- 11 people
- Sponsor
- Attikon Hospital
Critical Care, Oxygen Therapy
Comparison of Physiological Effects of Two Types of High-Flow Oxygen Therapy in Tracheostomized Patients
High-flow nasal oxygen therapy offers benefits like precise oxygen delivery, flow-related positive end-expiratory pressure generation and improved lung function.
- Conditions
- Critical Care, Oxygen Therapy, Tracheostomy
- Trial name
- NCT06816745
- Testing
- Modified high flow tracheal oxygen, Standard high flow tracheal oxygen
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Jian-Xin Zhou
Tracheotomy
Speaking Valve Combined With Airway Pressure Predicts Upper Airway Patency in Adult Tracheotomized Patients
This study was aimed to evaluate whether speaking valve combined with airway pressure could predict upper airway patency non-invasively in prolonged tracheostomized patients, identify candidates who need following endoscopy…
- Trial name
- NCT06521320
- Testing
- speaking valve combined with airway pressure, Bronchoscopy
- Where
- China
- Volunteers
- 248 people
- Sponsor
- Capital Medical University
Tracheostomy Decannulation
The Effect of Speaking Valve on Physiological Parameters With Wearable Devices
To explore the effect of speaking valves on physiological parameters of tracheostomized patients with wearable devices.
- Trial name
- Effect of SV (NCT07422350)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Jingyi Ge
Tracheostomized Patients
Influence of Tracheostomy on Lung Deposition in Spontaneously Breathing Patient
To compare lung deposition of amikacin in two settings: spontaneously breathing through a tracheostomy cannula and through the mouth.
- Trial name
- NCT01882595
- Testing
- Nebulization through the tracheostomy, Nebulization through the mouth
- Where
- Belgium
- Volunteers
- 9 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
High Flow Oxygen Therapy
Physiologic and Clinical Effect of High-flow Oxygen Therapy in Tracheostomized Patients With Prolonged Mechanical Ventilation Undergoing Weaning Trials
This study is aimed at patients who have been admitted to the respiratory care center of this hospital who meet the PMV conditions (defined as continuous use of the ventilator for at least ten days) who are about to receive the…
- Trial name
- NCT06357390
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital
Mechanical Ventilation Complication
Effect of Three Modalities of Spontaneous Breathing Tests on Respiratory Efforts in Tracheostomized Patients
Datas are lacking concerning weaning from mechanical ventilation for tracheostomized patients. In particular, the effect of different modalities of spontaneous breathing trials on respiratory effort has not been extensively…
- Trial name
- TWEEP (NCT03856424)
- Testing
- Modality 1, Modality 2, Modality 3
- Where
- Switzerland
- Volunteers
- 18 people
- Sponsor
- Piquilloud Imboden Lise
Tracheostomy, Airway Management
Reducing Decannulation Time: Limitation of Decannulation Capping Trials (REDECAP)
Multicenter randomized trial centered on critically-ill tracheostomized patients, comparing two different decannulation protocols: 1. based on capping trials to decide decannulation, 2.
- Conditions
- Tracheostomy, Airway Management, Respiratory Therapy
- Trial name
- REDECAP (NCT02512744)
- Testing
- Decannulation protocol., High flow conditioned oxygen therapy
- Where
- 5 sites in Spain
- Volunteers
- 330 people
- Sponsor
- Hospital Virgen de la Salud
Intracerebral Hemorrhage
Effect of Intermittent Oral Enteral Nutrition Tube in Tracheostomized Patients With Intracerebral Hemorrhage
This was a multicenter, prospective, randomized controlled clinical trail involved tracheostomized patients with Intracerebral Hemorrhage.
- Trial name
- NCT06304051
- Testing
- Intermittent Oro-esophageal Tube Feeding, Nasogastric Tube Feeding
- Where
- 2 sites in China
- Volunteers
- 118 people
- Sponsor
- Muhammad
Prolonged Mechanical Ventilation, Ventilator Weaning
Standardized Tracheostomy Weaning Protocol for Prolonged Mechanical Ventilation
This study evaluated the feasibility and clinical outcomes of a standardized weaning protocol for tracheostomized patients requiring prolonged mechanical ventilation.
- Conditions
- Prolonged Mechanical Ventilation, Ventilator Weaning, Tracheostomy
- Trial name
- NCT06642714
- Testing
- Standardized Stepwise Weaning Protocol
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Capital Medical University
Tracheostomy
Use of TrachPhone in Tracheostomized Patients
The use of Heat and Moisture Exchangers (HMEs) and their positive impact on pulmonary health have been extensively studied in patients with head and neck cancer but have not been systematically explored in other patient…
- Trial name
- NCT06487104
- Testing
- TrachPhone HME, External Humidifier (Usual Care)
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Atos Medical AB
Tracheostomy, Mechanical Ventilation
Trcheal High-flow for Weaning From Mechanical Ventilation
Multicentre randomized trial to determine whether tracheal high-flow nasal oxygen can improve weaning outcome vs. conventional oxygen therapy in critically ill tracheostomized patients who are hypoxemic.
- Conditions
- Tracheostomy, Mechanical Ventilation, Hypoxemic Respiratory Failure
- Trial name
- TRACFLOW (NCT07714564)
- Testing
- Oxygen therapy
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Tracheostomy, Prolonged Mechanical Ventilation
Incremental Dead Space Versus Capping Trial Before Tracheostomy Decannulation
Some critically ill patients need a breathing tube placed directly into the windpipe (tracheostomy) because they require long-term help from a breathing machine.
- Conditions
- Tracheostomy, Prolonged Mechanical Ventilation, Tracheostomy Decannulation
- Trial name
- NCT07810166
- Testing
- Incremental Instrumental Dead Space, Capping Trial
- Where
- Chile
- Volunteers
- 22 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Critical Illness, Tracheostomy Complication
Nebulized hypErtonic Saline for Better Prevention of mUcus pLug in Critical Adult Tracheostomized Patients
Tracheostomy is an important tool in the management of respiratory failure in the critically ill patient under mechanical ventilation.
- Conditions
- Critical Illness, Tracheostomy Complication, Mechanical Ventilation Complication, Plug; Mucus
- Trial name
- NEBULA (NCT03870646)
- Testing
- Hypertonic saline of NaCl (7%) in combination with hyaluronic acid, Isotonic saline of NaCl (0,9%)
- Where
- Spain
- Volunteers
- 164 people
- Sponsor
- Hospital Universitario Virgen de la Arrixaca
Chronic Obstructive Pulmonary Disease (COPD)
Tracheostomized COPD Patients and Non Invasive Mechanical Ventilation
The purpose of this study was to determine occurrence of ventilator associated pneumonia (VAP) in tracheostomized patients with COPD discharged in invasive mechanical ventilation (IMV) compared to patients with CPOPD discharged…
- Trial name
- NCT01285739
- Testing
- WBC, biomarkers, TBA, chest X ray
- Where
- Italy
- Volunteers
- 247 people
- Sponsor
- Fondazione Salvatore Maugeri
Tracheostomized Patients
High-Flow Tracheal Therapy on Tracheobronchial Secretions in Tracheostomized Patients
This monocentric, randomized crossover study aims to assess the impact of high-flow tracheal therapy (HFT) on the rheological properties of tracheobronchopulmonary secretions in tracheostomized patients.
- Trial name
- TRACH2O (NCT06897319)
- Testing
- High-Flow Tracheal Therapy
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Tracheostomy
SV With TTPEE Measurement Predicts Upper Airway Patency in Prolonged Tracheostomy Patients
The aim of this study is to evaluate the feasibility of predicting upper airway patency in patients with prolonged tracheostomy using a non-invasive method combining speaking valve (SV) and transtracheal end-expiratory pressure…
- Trial name
- NCT07107243
- Testing
- Speaking valve combined with airway pressure, Bronchoscopy
- Where
- 5 sites in China
- Volunteers
- 300 people
- Sponsor
- Capital Medical University
Tracheostomized Patients
Effect of High-Flow Tracheal Oxygen on EELI
The goal of this analytical experimental study is to evaluate whether high-flow tracheal oxygen therapy at flow rates above 60 L/min increases end-expiratory lung impedance in tracheostomized patients in the intensive care unit.
- Trial name
- NCT06824220
- Testing
- High-Flow Tracheal Oxygen
- Where
- Argentina
- Volunteers
- 11 people
- Sponsor
- Argentinian Intensive Care Society