Clinical trials: Tracheostomized Patients, active
Ventilated Patients
Nasal Airflow to Modulate Dyspnea in Tracheostomized Patients
The hypothesis of the present study is that restoring nasal stimulation alleviates dyspnea and improves respiratory drive. The aim of this study is to compare three non-pharmacological approaches designed to restore nasal…
- Trial name
- MODUS (NCT07308171)
- Testing
- Baseline, Installation of high flow humidified air cannula, Nasal air puffs
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Tracheostomy
SV With TTPEE Measurement Predicts Upper Airway Patency in Prolonged Tracheostomy Patients
The aim of this study is to evaluate the feasibility of predicting upper airway patency in patients with prolonged tracheostomy using a non-invasive method combining speaking valve (SV) and transtracheal end-expiratory pressure…
- Trial name
- NCT07107243
- Testing
- Speaking valve combined with airway pressure, Bronchoscopy
- Where
- 5 sites in China
- Volunteers
- 300 people
- Sponsor
- Capital Medical University
Tracheostomized Patients, Decanulation
Effects of a Perma-h Model Mobile-based Rehabilitation Support Program on Hope, Self-efficacy, Perceived Social Support and Rehabilitation Outcomes in Post- Tracheostomy Oral Cancer Patients
The goal of this study (exploratory sequential design; mixed-methods study) is to evaluate whether a PERMA-H model mobile-based rehabilitation support program delivered to post-tracheostomy oral cancer patients can improve…
- Conditions
- Tracheostomized Patients, Decanulation, Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer, Rehabilitation Outcome
- Trial name
- NCT07714967
- Testing
- PERMA-H model mobile-based rehabilitation support program
- Where
- 2 sites in China, Malaysia
- Volunteers
- 100 people
- Sponsor
- Hainan Medical College
Patient Satisfaction, Pulmonary Rehabilitation
Randomized Clinical Trial of the Application of TrachPhone HME and the Impact on Patient Satisfaction for Tracheostomized Head and Neck Cancer Patients
This study is being conducted at Tampa General Hospital. This study aims to evaluate the effectiveness of TrachPhone Heat Moisture Exchange (HME) on both patient satisfaction as well as improved pulmonary function with…
- Trial name
- HME (NCT07798414)
- Testing
- TrachPhone Heat Moisture Exchange, Trach Collar
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of South Florida
Tracheostomy
Use of TrachPhone in Tracheostomized Patients
The use of Heat and Moisture Exchangers (HMEs) and their positive impact on pulmonary health have been extensively studied in patients with head and neck cancer but have not been systematically explored in other patient…
- Trial name
- NCT06487104
- Testing
- TrachPhone HME, External Humidifier (Usual Care)
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Atos Medical AB
Tracheostomized Patients
Effect of High-Flow Tracheal Oxygen on EELI
The goal of this analytical experimental study is to evaluate whether high-flow tracheal oxygen therapy at flow rates above 60 L/min increases end-expiratory lung impedance in tracheostomized patients in the intensive care unit.
- Trial name
- NCT06824220
- Testing
- High-Flow Tracheal Oxygen
- Where
- Argentina
- Volunteers
- 11 people
- Sponsor
- Argentinian Intensive Care Society
Tracheostomy Decannulation
The Effect of Speaking Valve on Physiological Parameters With Wearable Devices
To explore the effect of speaking valves on physiological parameters of tracheostomized patients with wearable devices.
- Trial name
- Effect of SV (NCT07422350)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Jingyi Ge
Prolonged Disorders of Consciousness, Tracheostomy
A Speaking-Valve-Based Decannulation Protoco for Patients With a Prolonged Disorders of Consciousness
To evaluate the feasibility of a standardized tracheostomy decannulation protocol for patients with prolonged Disorders of Consciousness (pDoC) .
- Trial name
- STEP-DoC (NCT07183670)
- Testing
- decannulation protocol
- Where
- 2 sites in China
- Volunteers
- 184 people
- Sponsor
- Hongying Jiang, MD
Tracheostomized Patients, Mechanical Ventilation Weaning
High Flow Tracheal Oxygen for Weaning of Tracheostomized Patients
In this pilot randomized controlled trial (RCT), the investigators aim to explore the feasibility of conducting a powered RCT that examines the efficacy and safety of high flow tracheal oxygen (HFTO) in weaning critically ill…
- Conditions
- Tracheostomized Patients, Mechanical Ventilation Weaning, High Flow Oxygen Therapy
- Trial name
- HFTO-WEAN (NCT07559591)
- Testing
- High-flow tracheal oxygen (HFTO), Tracheal Mask (TM)
- Where
- Saudi Arabia
- Volunteers
- 88 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Stroke Patients, Tracheostomy
A Speaking-Valve-Based Decannulation Protocol for Tracheostomized Stroke Patients
To evaluate the feasibility of a speaking-valve-based decannulation protocol in tracheostomized stroke patients
- Trial name
- SVBDP-TSP (NCT07904169)
- Testing
- Decannulation Protocol
- Volunteers
- 207 people
- Sponsor
- Hongying Jiang, MD
Tracheostomy, Prolonged Mechanical Ventilation
Incremental Dead Space Versus Capping Trial Before Tracheostomy Decannulation
Some critically ill patients need a breathing tube placed directly into the windpipe (tracheostomy) because they require long-term help from a breathing machine.
- Conditions
- Tracheostomy, Prolonged Mechanical Ventilation, Tracheostomy Decannulation
- Trial name
- NCT07810166
- Testing
- Incremental Instrumental Dead Space, Capping Trial
- Where
- Chile
- Volunteers
- 22 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Critical Care, Oxygen Therapy
Comparison of Physiological Effects of Two Types of High-Flow Oxygen Therapy in Tracheostomized Patients
High-flow nasal oxygen therapy offers benefits like precise oxygen delivery, flow-related positive end-expiratory pressure generation and improved lung function.
- Conditions
- Critical Care, Oxygen Therapy, Tracheostomy
- Trial name
- NCT06816745
- Testing
- Modified high flow tracheal oxygen, Standard high flow tracheal oxygen
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Jian-Xin Zhou
Neuromuscular Diseases (NMD), ALS (Amyotrophic Lateral Sclerosis)
Invasive Home Ventilation in Denmark
The aim of this study is to describe national trends over the past 10 years in patients receiving invasive home mechanical ventilation (HMV) in Denmark.
- Conditions
- Neuromuscular Diseases (NMD), ALS (Amyotrophic Lateral Sclerosis), Spinal Cord Injuries (SCI), Duchenne Muscular Dystrophy (DMD)
- Trial name
- HOMEVENT DK (NCT07467187)
- Where
- Denmark
- Volunteers
- 450 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Tracheostomized Patients
High-Flow Tracheal Therapy on Tracheobronchial Secretions in Tracheostomized Patients
This monocentric, randomized crossover study aims to assess the impact of high-flow tracheal therapy (HFT) on the rheological properties of tracheobronchopulmonary secretions in tracheostomized patients.
- Trial name
- TRACH2O (NCT06897319)
- Testing
- High-Flow Tracheal Therapy
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Tracheostomy, Mechanical Ventilation
Trcheal High-flow for Weaning From Mechanical Ventilation
Multicentre randomized trial to determine whether tracheal high-flow nasal oxygen can improve weaning outcome vs. conventional oxygen therapy in critically ill tracheostomized patients who are hypoxemic.
- Conditions
- Tracheostomy, Mechanical Ventilation, Hypoxemic Respiratory Failure
- Trial name
- TRACFLOW (NCT07714564)
- Testing
- Oxygen therapy
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Weaning Failure
Role of Regional Lung Compliance and Dynamic Transpulmonary Driving Pressure in the Liberation Difficulty in Tracheostomized Patients Receiving Prolonged Mechanical Ventilation
This project focuses on the analysis of the correlation between transpulmonary driving pressure and uneven lung ventilation and regional lung compliance in patients using prolonged mechanical ventilation (PMV), in order to…
- Trial name
- NCT07003672
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital