Clinical trials: Tracheostomy, open to volunteers
Stroke Patients, Tracheostomy
A Speaking-Valve-Based Decannulation Protocol for Tracheostomized Stroke Patients
To evaluate the feasibility of a speaking-valve-based decannulation protocol in tracheostomized stroke patients
- Trial name
- SVBDP-TSP (NCT07904169)
- Testing
- Decannulation Protocol
- Volunteers
- 207 people
- Sponsor
- Hongying Jiang, MD
Tracheotomy Patients, Airway Management
Feasibility and Safety of the Airway Exchange Broncholaryngoscope (AEBLScope)
This pilot study evaluates the safety and feasibility of a novel airway exchange broncholaryngoscope (AEBLScope) during routine tracheostomy tube exchanges in chronically tracheostomy-dependent adult outpatients.
- Conditions
- Tracheotomy Patients, Airway Management, Airway Disease
- Trial name
- NCT07033702
- Testing
- Airway-Exchange Broncholaryngoscope (AEBLScope)
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Southern California
Neoplasms, Airway Obstruction Upper
Difficult Airway Management in Oncology: An International Delphi Consensus Study (DAMO)
Airway management in patients with cancer carries risks that general difficult-airway guidelines do not address. Tumour in the head, neck, or mediastinum can distort or narrow the airway; previous radiotherapy causes fibrosis and…
- Conditions
- Neoplasms, Airway Obstruction Upper, Intubation, Intratracheal, Head and Neck Neoplasms
- Trial name
- DAMO (NCT07822815)
- Testing
- Questionnaire Administration
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Onco Critical Care Society
Physiological Parameters, Wearable Devices
Physiological Benefits From the Removal of Tracheostomy Tubes (Obtained Via Wearable Devices)
The population included in this study consists of tracheostomy patients admitted to the pulmonary department of Beijing Rehabilitation Hospital, undergoing decannulation rehabilitation treatment.
- Conditions
- Physiological Parameters, Wearable Devices, Tracheostomy Decannulation
- Trial name
- RVTR1 (NCT07424196)
- Testing
- Successful decannulation group
- Volunteers
- 60 people
- Sponsor
- Bin Zhang
Intubated Patients, Percutaneous Tracheostomy
C-MAC Videolaryngoscopy Versus Direct Laryngoscopy for Percutaneous Tracheostomy
When preparing an ICU patient for percutaneous dilational tracheostomy, correct positioning of the endotracheal tube is important. During the procedure, it is possible to puncture the cuff.
- Trial name
- VIDLARTRAQ (NCT05416489)
- Testing
- C-MAC videolayngoscopy technique, Laryngoscopy technique
- Where
- 2 sites in Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Stroke
Comparison of Speaking Valve Trial and Capping Trial for Tracheostomy Decannulation in Stroke Patients
This study aims to compare the efficacy and safety of the Speaking Valve trial versus the traditional Capping trial as indicators for tracheostomy decannulation in stroke patients.
- Trial name
- NCT07435727
- Testing
- Passy-Muir Speaking Valve, Tracheostomy tube capping
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Hongying Jiang, MD
Tracheostomy
Tracheostomy Robotics and Cutting-edge Health Education for Airway Safety
The goal of this clinical trial is to test the NextGen Tracheostomy Toolkit in people who have a tracheostomy. The main questions it aims to answer are: What is the number of atraumatic tracheostomy suctionings before and after…
- Trial name
- TRACHEAS (NCT06236542)
- Testing
- NextGen automated tracheostomy suctioning device, NextGen mixed-reality tracheostomy tube change system, NextGen Tracheostomy Toolkit
- Where
- 2 sites in United States
- Volunteers
- 632 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Communication Barriers
Understanding Communication Barriers in Acute Care: A Mixed-Methods Needs Assessment Among Healthcare Providers Caring for Non-Verbal Patients With Spinal Cord Injury and Tracheostomy in the ICU
Communication impairment is common among critically ill patients who are mechanically ventilated, have tracheostomies, or have neurological injuries such as spinal cord injury.
- Trial name
- NCT07796035
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Tracheostomy Patients, Multidisciplinary Care Team
Evaluation of a Specialised Tracheostomy Team for the Management of Patients With a Tracheostomy Cannula in a Belgium General Hospital: A Retrospective Study.
Patients admitted to intensive care units (ICUs) frequently require prolonged mechanical ventilation. Difficulties in weaning from mechanical ventilation represent an important indication for performing a tracheotomy, which…
- Conditions
- Tracheostomy Patients, Multidisciplinary Care Team, Outcomes, Hospital
- Trial name
- NCT07755969
- Testing
- The implementation of the specialised multidisciplinary tracheostomy team.
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Vitaz
Tracheostomy
SV With TTPEE Measurement Predicts Upper Airway Patency in Prolonged Tracheostomy Patients
The aim of this study is to evaluate the feasibility of predicting upper airway patency in patients with prolonged tracheostomy using a non-invasive method combining speaking valve (SV) and transtracheal end-expiratory pressure…
- Trial name
- NCT07107243
- Testing
- Speaking valve combined with airway pressure, Bronchoscopy
- Where
- 5 sites in China
- Volunteers
- 300 people
- Sponsor
- Capital Medical University
Surveillance, Endoscopy
"Airway Complications in Pediatric Patients With Tracheostomies: To What Extent Can Symptoms Identified by Caregivers or Pediatricians Serve as Predictors for Airway Complications Confirmed Through Surveillance Endoscopy?"
Study Objective: This observational study aims to prospectively investigate to what extent tracheostomy-related complications in children are asymptomatic or associated with symptoms when detected through surveillance airway…
- Conditions
- Surveillance, Endoscopy, Tracheostomy Complication, Tracheostomy Complications
- Trial name
- NCT07121517
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska Institutet
Guillain Barre Syndrome, Mechanical Ventilation
Early vs. Late Tracheostomy in Patients With Guillain -Barre Syndrome
Tracheostomy is one of the most common procedures in the intensive care unit in patients who need prolonged invasive mechanical ventilation.
- Trial name
- NCT06612242
- Testing
- early tracheostomy (less than 7 days from intubation), Late tracheostomy (more than 7 days from intubation)
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Meir Medical Center
Tracheostomy, Caregiver Burden
Boosting Resources for Tracheostomy Care at Home
The goal of this trial is to advance the understanding of how to best support caregivers of children with tracheostomies who are caring for their child at home.
- Trial name
- BREATHE (NCT06283953)
- Testing
- Trach Plus, Trach Me Home
- Where
- 6 sites in United States
- Volunteers
- 480 people
- Sponsor
- Massachusetts General Hospital
Head and Neck Cancer, Radiation Dermatitis Acute
Using Silverlon® for Head and Neck Patients With Tracheostomies
The purpose of this study is to determine if prophylactic silver-nylon burn dressing Silverlon® prevents a severe skin reaction under tracheostomy collars.
- Conditions
- Head and Neck Cancer, Radiation Dermatitis Acute, Radiation Treatment
- Trial name
- NCT07856732
- Testing
- Silverlon®
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- State University of New York - Upstate Medical University
Tracheostomized Patients, Decanulation
Effects of a Perma-h Model Mobile-based Rehabilitation Support Program on Hope, Self-efficacy, Perceived Social Support and Rehabilitation Outcomes in Post- Tracheostomy Oral Cancer Patients
The goal of this study (exploratory sequential design; mixed-methods study) is to evaluate whether a PERMA-H model mobile-based rehabilitation support program delivered to post-tracheostomy oral cancer patients can improve…
- Conditions
- Tracheostomized Patients, Decanulation, Oral Cancer , Oral Squamous Cell Carcinoma, Oral Cavity Cancer, Rehabilitation Outcome
- Trial name
- NCT07714967
- Testing
- PERMA-H model mobile-based rehabilitation support program
- Where
- 2 sites in China, Malaysia
- Volunteers
- 100 people
- Sponsor
- Hainan Medical College
Laryngotracheal Lesions, Tracheostomy Complications
Laryngotracheal Lesions in Adults With Long-Term Tracheostomy
This multicenter prospective observational cohort study will enroll 224 adults with a tracheostomy tube in place for at least 14 days.
- Conditions
- Laryngotracheal Lesions, Tracheostomy Complications, Tracheal Stenosis, Tracheomalacia
- Trial name
- NCT07901946
- Testing
- Standardized Three-Station Bronchoscopy
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Hongying Jiang, MD
Tracheostomy
Speaking Valve Influence on Breathing, Swallowing and Vocal Functions in Patients With Tracheostomy.
Speaking valve seems to have a beneficial influence on breathing and secretion management in certain patients with tracheostomy.
- Trial name
- NCT05482022
- Testing
- Shiley™ phonate speaking valve, control
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Loewenstein Hospital
Trachea Diseases, Tracheal Stenosis
Feasibility of Tracheobronchial Reconstruction Using Allogenic Aortic Patch in Children
Feasibility and safety of repairing tracheal and bronchial defects in infants and children using cryopreserved donor aortic patches.
- Conditions
- Trachea Diseases, Tracheal Stenosis, Tuberculosis; Tracheitis, Airway Disease
- Trial name
- NCT07240259
- Testing
- Cryopreserved aorta
- Where
- Taiwan
- Volunteers
- 5 people
- Sponsor
- National Taiwan University Hospital
Respiratory Distress Syndrome (RDS), Respiratory Ilness
Study on the Correlation Between Tracheotomy Tip Pressure and Esophageal Pressure in Patients Weaned from Tracheotomy
Whether the correlation between gas incision tip pressure fluctuations (ΔPtt) and esophageal pressure fluctuations (ΔPes) is a potential measure of spontaneous respiratory effort in patients undergoing gas incision offline.
- Trial name
- NCT06783777
- Testing
- Esophageal pressure monitoring, Tracheotomy tip pressure
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Shanghai Zhongshan Hospital
Tracheostomized Patients, Mechanical Ventilation Weaning
High Flow Tracheal Oxygen for Weaning of Tracheostomized Patients
In this pilot randomized controlled trial (RCT), the investigators aim to explore the feasibility of conducting a powered RCT that examines the efficacy and safety of high flow tracheal oxygen (HFTO) in weaning critically ill…
- Conditions
- Tracheostomized Patients, Mechanical Ventilation Weaning, High Flow Oxygen Therapy
- Trial name
- HFTO-WEAN (NCT07559591)
- Testing
- High-flow tracheal oxygen (HFTO), Tracheal Mask (TM)
- Where
- Saudi Arabia
- Volunteers
- 88 people
- Sponsor
- King Faisal Specialist Hospital & Research Center