Clinical trials: Tracheostomy Patients
Weaning Failure, Mechanical Ventilation
Weaning With Tracheostomy - an Observational Study on Patient-centered Outcomes
Background: It is largely undocumented how long it takes to wean from invasive mechanical ventilation (IMV) with tracheostomy and to what extend these patients suffer from dyspnea or discomfort and how often sputum retention…
- Conditions
- Weaning Failure, Mechanical Ventilation, Patient-centered Care
- Trial name
- Wean-Trach (NCT05906888)
- Where
- 13 sites in Netherlands
- Volunteers
- 156 people
- Sponsor
- Henrik Endeman
Tracheostomy
An Investigator-initiated Study to Evaluate Safety and Efficacy of ARINA-1 in People With a Tracheostomy
The goal of this investigator-initiated, open label study is to evaluate the safety and efficacy of ARINA-1 in people with a tracheostomy. Participants will attend study visits at Screening, Baseline, Day 14, Day 28, and Day 56.
- Trial name
- NCT05658029
- Testing
- ARINA-1
- Where
- United States
- Sponsor
- Matthew Bruehl
COPD, Tracheostomy
Azithromycin Treatment of Patients With Chronic Obstructive Pulmonary Disease (COPD) and Tracheostomy
Aims of the study to evaluate the rate of enteric gram negative bacteria colonization in tracheotomised COPD patients to evaluate the effect of azithromycin long-term treatment on Pseudomonas aeruginosa colonization and colony…
- Trial name
- NCT00323986
- Testing
- azithromycin (drug)
- Where
- 3 sites in Italy
- Volunteers
- 30 people
- Sponsor
- University of Milan
Acute Lung Injury, Mechanical Ventilation
NAV-ALI: Neurally Adjusted Ventilatory Assist in Patients Recovering Spontaneous Breathing After Acute Lung Injury
Evaluation of a new ventilatory mode Neurally Adjusted Ventilatory Assist "NAVA" in patients who recover spontaneous breathing after acute lung injury.
- Trial name
- NCT00963066
- Testing
- PSV - pressure suppot ventilation, NAVA - Neurally Adjusted Ventilatory Assist, NAVA - EMG
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Caen
Respiration, Artificial
Evaluation of the Versamed iVent in the Transport of Patients Receiving Mechanical Ventilation
The purpose of this study is to evaluate the use of the VersaMed iVent ventilator in the acute care setting, hypothesizing that, in comparison to the standard approach, the use of the VersaMed will facilitate transport and reduce…
- Trial name
- iVent (NCT00652756)
- Testing
- Use of ventilator during patient transport (Versamed iVent), Bag-valve ventilation
- Where
- United States
- Sponsor
- Tufts Medical Center
Tracheostomized Patients, Depression
The Effect of Mobile Application-Based Education Given to Patients With Tracheostomy on Depression, Social Adaptation and Quality of Recovery
The Effect of Mobile Application-Based Education Given to Patients with Tracheostomy on Depression, Social Adaptation and Quality of Recovery
- Conditions
- Tracheostomized Patients, Depression, Social Adaptation, Quality of Recovery
- Trial name
- NCT07337668
- Testing
- Mobile application-based education, Standart Care
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Saglik Bilimleri Universitesi
Muscular Dystrophies, Intensive Care (ICU) Myopathy
Prognostic Factors , Morbidity and Mortality in Patients With Neuromuscular Disorders Admitted in ICU
Muscular dystrophies are neuromuscular disorders with disability. Restrictive pulmonary failure and cardiomyopathy affect prognosis.The investigators aim to establish predictive factors for mortality and morbidity in Intensive…
- Trial name
- NCT02685215
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Tracheostomy Patients, Multidisciplinary Care Team
Evaluation of a Specialised Tracheostomy Team for the Management of Patients With a Tracheostomy Cannula in a Belgium General Hospital: A Retrospective Study.
Patients admitted to intensive care units (ICUs) frequently require prolonged mechanical ventilation. Difficulties in weaning from mechanical ventilation represent an important indication for performing a tracheotomy, which…
- Conditions
- Tracheostomy Patients, Multidisciplinary Care Team, Outcomes, Hospital
- Trial name
- NCT07755969
- Testing
- The implementation of the specialised multidisciplinary tracheostomy team.
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Vitaz
Tracheostomy
The Application and Analysis of Diaphragm Electrical Impulse in Adult Patients With Spontaneous Breathing Trial
The aim of this study is to investigate the use of Edi in patients under the endotracheal tube and tracheostomy, and analysis of cardiopulmonary parameters in adult patients.
- Trial name
- NCT05241002
- Where
- Taiwan
- Volunteers
- 4 people
- Sponsor
- Fu Jen Catholic University
Tracheostomy, Mechanical Ventilation Complication
Efficacy and Safety of the DYNAtraq Device to Prevent Complications in Tracheostomy in Mechanically Ventilated Patients
Although tracheostomy is a common technique in Intensive Care Units (ICU), its complications can be frequent (between 5% to 40%).
- Trial name
- DYNAtraq (NCT04668742)
- Testing
- DYNAtraq
- Where
- Colombia
- Volunteers
- 74 people
- Sponsor
- Fundación Cardiovascular de Colombia
Respiratory Insufficiency
Early Tracheotomy Versus Prolonged Endotracheal Intubation in Intensive Care Unit (ICU) Patients
This is a phase III trial comparing early tracheotomy versus prolonged endotracheal intubation in intensive care unit patients needing prolonged ventilatory support.
- Trial name
- NCT00127621
- Testing
- early tracheotomy, prolonged endotracheal intubation
- Where
- France
- Volunteers
- 468 people
- Sponsor
- Gustave Roussy, Cancer Campus, Grand Paris
Chronic Respiratory Failure
Impact of Patient Controlled Positive End-expiratory Pressure on Speech in Tracheostomized Ventilated Patients
Adequate communication is a major part of the quality of life of tracheostomized ventilator dependent patients. Maintaining speech is therefore major goal in the management of these patients.
- Trial name
- OptiPEP (NCT01479959)
- Testing
- Eole 3 ventilator - Resmed
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University of Versailles
Ischemic Stroke, Intracerebral Hemorrhage
Early Tracheostomy in Ventilated Stroke Patients
Patients with severe ischemic and hemorrhagic strokes, who require mechanical ventilation, have a particularly bad prognosis. If they require long-term ventilation, their orotracheal tube needs to be, like in any other intensive…
- Conditions
- Ischemic Stroke, Intracerebral Hemorrhage, Subarachnoid Hemorrhage
- Trial name
- SETPOINT (NCT01261091)
- Testing
- Early Tracheostomy, Late Tracheostomy
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Heidelberg University
Tracheotomy Patients, Airway Management
Feasibility and Safety of the Airway Exchange Broncholaryngoscope (AEBLScope)
This pilot study evaluates the safety and feasibility of a novel airway exchange broncholaryngoscope (AEBLScope) during routine tracheostomy tube exchanges in chronically tracheostomy-dependent adult outpatients.
- Conditions
- Tracheotomy Patients, Airway Management, Airway Disease
- Trial name
- NCT07033702
- Testing
- Airway-Exchange Broncholaryngoscope (AEBLScope)
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Southern California
Head Injury, Traumatic Brain Injury
Outcomes of Early Versus Late Tracheostomy in Critically Ill Patients Due to Head Injury: A Randomized Controlled Trial
Tracheostomy is a surgical procedure that involves creating an opening in the trachea and bringing it to the skin surface to form a stoma. It may be performed as an emergency or elective operation.
- Trial name
- NCT07872865
- Testing
- Tracheostomy
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- University Of Anbar
Respiratory Failure, Cardiovascular Surgery
Early Percutaneous Tracheostomy for Cardiac Surgery (ETOC)
This is a phase III clinical trial comparing early tracheostomy (day 4) versus prolonged endotracheal intubation in ICU patients needing prolonged ventilatory support after cardiovascular surgery.
- Trial name
- ETOC (NCT00347321)
- Testing
- Dilatational Percutaneous tracheostomy
- Where
- France
- Volunteers
- 212 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Tracheostomy Complication, Acquired Brain Injury
Cough Assessment in Patients With Severe Acquired Brain Injury
The cough assessment is fundamental in the weaning process as it gives information on the possibility to expel food and secretion out from the airways.
- Conditions
- Tracheostomy Complication, Acquired Brain Injury, Brain Injury, Pneumonia
- Trial name
- NCT02495558
- Testing
- Reflex Cough Test
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Tracheotomy
Impact of Tracheotomy on Procalcitonin
Procalcitonin (PCT) is a reliable biomarker of infection and sepsis. The investigators aimed to determine whether tracheotomy influences PCT concentrations in patients without sepsis, and to assess whether operative duration and…
- Trial name
- NCT02406079
- Testing
- tracheotomy
- Volunteers
- 1 people
- Sponsor
- First People's Hospital of Chenzhou
Tracheostomized Patients
Effect of High-Flow Tracheal Oxygen on EELI
The goal of this analytical experimental study is to evaluate whether high-flow tracheal oxygen therapy at flow rates above 60 L/min increases end-expiratory lung impedance in tracheostomized patients in the intensive care unit.
- Trial name
- NCT06824220
- Testing
- High-Flow Tracheal Oxygen
- Where
- Argentina
- Volunteers
- 11 people
- Sponsor
- Argentinian Intensive Care Society
Respiratory Failure, Traumatic Brain Injury
A Prospective, Randomized Trial of Early Versus Late Tracheostomy in Trauma Patients With Severe Brain Injury
The purpose of this study is to evaluate the efficacy of early conversion tracheostomy from endotracheal intubation (ET) to percutaneous, dilatational tracheostomy (PDT) in traumatic brain-injured patients requiring prolonged…
- Trial name
- NCT00292097
- Testing
- Early tracheostomy, Late tracheostomy
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Memorial Medical Center