Clinical trials: Transcranial Direct Current Stimulation(tDCS)
Alzheimer Disease
Understanding How Alzheimer's Disease Impacts the Therapeutic Response to Transcranial Direct Current Stimulation
There is currently little symptomatic therapy for Alzheimer's Disease (AD) and nothing effective for individuals with Frontotemporal dementia (FTD).
- Trial name
- NCT05508841
- Testing
- tDCS and Cognitive Training
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Baycrest
Chronic Low Back Pain
Transcranial Stimulation for Physiotherapy Optimisation - Chronic Low Back Pain (STOP-CLBP)
The main objective of this study is to investigate the effects of non-invasive brain stimulation (the so-called transcranial direct current stimulation ; tDCS) combined with an active physiotherapy program on the multidimensional…
- Trial name
- STOP-CLBP (NCT05757609)
- Testing
- Anodal tDCS combined with active physiotherapy
- Where
- Switzerland
- Volunteers
- 48 people
- Sponsor
- Stephane ARMAND
Dementia, Memory Loss
Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia
This project aims to examine the efficacy of remote, caregiver-led tES/brain stimulation intervention targeted to improve memory, mobility, and executive functioning among older adults with mild cognitive impairment or mild…
- Conditions
- Dementia, Memory Loss, Alzheimer Disease, Executive Dysfunction
- Trial name
- ACDCStim (NCT05661084)
- Testing
- Transcranial alternating current stimulation (tACS) (active); Transcranial direct current stimulation (tDCS) (active)
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Hebrew SeniorLife
Stroke
Effect of Combining Central and Peripheral Cutaneous Electrical Stimulation on Lower Limb Motor Function in People With Stroke
This study aims to evaluate the effectiveness of transcranial direct current stimulation (tDCS) and transcutaneous electrical nerve stimulation (TENS) in augmenting the efficacy of the lower limb task-oriented training in people…
- Trial name
- NCT06838013
- Testing
- Transcranial direct current stimulation (tDCS), Bilateral Transcutaneous electrical nerve stimulation (Bi-TENS), Lower-limb task-oriented training
- Where
- Hong Kong
- Volunteers
- 92 people
- Sponsor
- The Hong Kong Polytechnic University
Obsessive-Compulsive Disorder
Transcranial Direct Current Stimulation (tDCS) in the Treatment of Drug-naïve Obsessive-compulsive Disorder(OCD)
This study will evaluate the possible therapeutic effects of Transcranial Direct Current Stimulation (tDCS) in drug-naïve obsessive-compulsive disorder (OCD) patients, and the underlying neural mechanism by magnetic resonance…
- Trial name
- NCT04086446
- Testing
- high-definition transcranial direct current stimulation
- Where
- China
- Volunteers
- 47 people
- Sponsor
- Shanghai Mental Health Center
Aphasia, Global, Stroke
tDCS and Speech Therapy to Improve Aphasia
To study the effect of combined tDCS plus speech therapy compared to sham-tDCS plus speech therapy in subacute stroke patients suffering from moderate or severe aphasia.
- Conditions
- Aphasia, Global, Stroke, Transcranial Direct Current Stimulation, Speech Therapy
- Trial name
- MP-LOGA (NCT02395874)
- Testing
- tDCS + speech therapy
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Medical Park AG
Motor Learning
How Many Days Would You Want to Practice a Skill to Achieve it?
Practice is required to improve your shot in basketball or to play a musical instrument. The learning of these motor skills can be further enhanced by non-invasively stimulating regions of the brain that control movements with…
- Trial name
- NCT03249961
- Testing
- Anodal TDCS, Transcranial Magnetic Stimulation (TMS)
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Stroke
Repetitive Bihemispheric Transcranial Direct Current Stimulation After Stroke
Non-invasive repetitive bi-hemispheric transcranial direct current stimulation (tDCS) may restore post-stroke bi-hemispheric balance by increase peri-lesional cortex activity and suppress abnormal inhibition from non-lesional…
- Trial name
- NCT02731508
- Testing
- Bihemispheric transcranial direct current stimulation
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Stroke
Combine Transcranial Direct Current Stimulation and Neuromuscular Electrical Stimulation on Stroke Patients
Transcranial direct current stimulation (tDCS) has been shown not only to improve motor function but also increase cortical excitability and neural plasticity.
- Trial name
- NCT02821884
- Testing
- Combination of tDCS and NMES
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Depression
Postmarketing Clinical Trial of tDCS to Evaluate Cognitive Ability in Depression Patients
This study is a multicenter, double-blind, randomized, and confirmed clinical trial in patients taking antidepressants during the 6-week stimulation period , sham stimulation group, low real stimulation group (1mA), high real…
- Trial name
- NCT04709952
- Testing
- Transcranial direct current stimulation_High real, Transcranial direct current stimulation_Low real
- Where
- 2 sites in South Korea
- Volunteers
- 141 people
- Sponsor
- ji hyun baek, MD, Ph.D
Cortical Excitability, Motor Performance
The Effect of tDCS on Motor Performance and Cortical Excitability
In this study the effect of tDCS intensity on motor performance and corticospinal (CS) excitability is evaluated. The investigators expect that a positive relationship between current intensity and motor performance/CS…
- Conditions
- Cortical Excitability, Motor Performance, tDCS
- Trial name
- NCT01740843
- Testing
- transcranial direct current stimulation (tDCS) (NeuroConn DC-stimulator)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Amyotrophic Lateral Sclerosis
Transcranial Direct Current Stimulation as a Novel Therapeutic Approach in Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized by progressive weakness and muscular atrophy due to the degeneration and loss of motor neurons, the nerve cells that, in the central nervous system…
- Trial name
- NCT01569958
- Testing
- transcranial direct current stimulation
- Where
- 3 sites in Italy
- Volunteers
- 54 people
- Sponsor
- Università degli Studi 'G. d'Annunzio' Chieti e Pescara
Chronic Pelvic Pain
Open Label Extension Study of tDCS Plus Guided Imagery for Women With Chronic Pelvic Pain (CPP)
This is an open label extension study trial of tDCS with a standardized guided imagery intervention. Up to 20 women with chronic pelvic pain, who completed participation in the initial randomized trial (IRB 2019-362) will be…
- Trial name
- NCT04252040
- Testing
- Active tDCS with guided imagery
- Where
- 2 sites in United States
- Sponsor
- Corewell Health East
Subacute Stroke, Upper Extremity Function
AI-based Customized tDCS for Finger Motor Recovery After Subacute Stroke
The goal of this clinical study is to evaluate whether AI-based customized transcranial direct current stimulation (tDCS) using MR images is more effective than sham stimulation in improving finger motor function in patients with…
- Trial name
- NCT07491029
- Testing
- AI-based Customized transcranial Direct Current Stimulation
- Where
- South Korea
- Volunteers
- 116 people
- Sponsor
- NEUROPHET
Amblyopia
Bilateral Transcranial Direct Current Stimulation and Ocular Occlusion for Adults With Amblyopia
A prospective interventional study is expected to be conducted, to test a possible new treatment for amblyopia (lazy eye syndrome).
- Trial name
- NCT05016830
- Testing
- Bilateral transcranial direct current stimulation
- Where
- Chile
- Volunteers
- 12 people
- Sponsor
- University of Chile
Obsessive-Compulsive Symptom
Efficacy of Intensified Transcranial Direct Current Stimulation in Obsessive-compulsive Disorder
This is a randomized, double-blind, parallel-group, sham-controlled trial that aims to investigate the effectiveness of transcranial direct current stimulation (TDCS) on improving symptoms, quality of life, depression, and…
- Trial name
- NCT05501132
- Testing
- transcranial direct current stimulation
- Where
- Iran
- Volunteers
- 42 people
- Sponsor
- The National Brain Mapping Laboratory (NBML)
Healthy
Dual Site-Dual Channel Non-invasive Brain Stimulation for Motor Function in Healthy Subjects
The aim of this study is to investigate the effect of dual site-dual channel non-invasive brain stimulation for recovery of motor function in healthy subjects.
- Trial name
- NCT03486795
- Testing
- M1 stimulation, PMC stimulation
- Where
- South Korea
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Stress
Home-based Stimulation to Promote Resilience
Background: Non-invasive brain stimulation showed to be effective in reduce stress related cognitive and mental-health consequences.
- Trial name
- NCT06051071
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Institut Guttmann
Fibromyalgia, Chronic Pain
Single-arm, Open-label, Phase II Trial of HD-tDCS in Fibromyalgia Patients
The purpose of this study is to investigate the mean number of stimulation (high definition-transcranial direct current stimulation) sessions (up to 26) needed to achieve a clinical response with this response defined as a 50%…
- Trial name
- NCT01842009
- Testing
- High Definition transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Spaulding Rehabilitation Hospital
Mild Cognitive Impairment
Effects of tDCS on Cognition in MCI: A RCT
MCI is considered an intermediate stage between normal cognitive aging and dementia. As such, improving cognitive functions of people with MCI may delay dementia onset.
- Trial name
- NCT05584748
- Testing
- transcranial direct current stimulation
- Volunteers
- 48 people
- Sponsor
- Tung Wah College
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