Clinical trials: Transcutaneous Vagal Nerve Stimulation
Tic Disorders
Neuromodulation of Inhibitory Control in Tic Disorders
The present study aims to assess the effects of non invasive electrical stimulation of the vagus nerve via transcutaneous vagus nerve stimulation (tVNS) on cognitive functions, inhibitory and tic control in patients with tic…
- Trial name
- NCT05263414
- Testing
- tVNS
- Where
- Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Depression - Major Depressive Disorder
Slow-Paced Breathing and Electrical Vagus Nerve Stimulation as Add-on Treatments for Depression
Depression is a common mental health condition, and standard psychiatric therapies do not always lead to satisfactory recovery. As a result, there is an urgent need for effective, complementary treatments.
- Trial name
- Add-Vagus (NCT07844733)
- Testing
- Slow-Paced Breathing, Transcutaneous Auricular Vagus Nerve Stimulation (tVNS), Treatment as Usual (TAU)
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- Elisabeth Balint
Healthy Volunteers
Using a Transcutaneous Electrical Auricular Stimulator to Harness the Cholinergic Anti-Inflammatory Pathway
Persistent chronic inflammation is an important underlying event in multiple diseases including rheumatoid arthritis, inflammatory bowel diseases and type 2 diabetes.
- Trial name
- TEACAP (NCT02910973)
- Testing
- Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Complex Regional Pain Syndrome Type I
Transcutaneous Auricular Vagus Nerve Stimulation Added to Rehabilitation for Complex Regional Pain Syndrome Type I
This randomized, participant- and assessor-blinded, sham-controlled study will evaluate the effectiveness of transcutaneous auricular vagus nerve stimulation (taVNS) added to standard rehabilitation in adults with complex…
- Trial name
- taVNS-CRPS-I (NCT07711392)
- Testing
- Active Transcutaneous Auricular Vagus Nerve Stimulation, Standard Rehabilitation Program
- Volunteers
- 20 people
- Sponsor
- Liv Hospital Vadistanbul
Traumatic Brain Injury, Upper Extremity
Transcutaneous Auricular Vagus Nerve Stimulation to Improve Upper Extremity Recovery After Traumatic Brain Injury
Upper extremity weakness, impaired coordination, reduced dexterity, and limited arm and hand use may continue after TBI. Repetitive, task-specific rehabilitation may improve function, but recovery can remain incomplete.
- Trial name
- taVNS (NCT07867015)
- Testing
- taVNS, FTP
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Craig Hospital
Chronic Neck Pain
Effects of the Timing of Vagus Nerve Stimulation Combined With Exercise in Chronic Neck Pain
This randomized, sham-controlled, parallel-group clinical trial aims to investigate whether the timing of transcutaneous auricular vagus nerve stimulation (taVNS) relative to therapeutic exercise influences pain intensity…
- Trial name
- NCT07769034
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Kutahya Health Sciences University
Disorders of Consciousness
Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Patients With Disorders of Consciousness
Consciousness disorders following severe brain injury refer to a series of disturbances in arousal and cognition secondary to organic brain diseases, including Unresponsive Wakefulness Syndrome (UWS) (also termed Vegetative…
- Trial name
- taVNS (NCT07284732)
- Testing
- transcutaneous auricular vagus nerve stimulation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Zhujiang Hospital
Erosive Osteo-Arthritis, Hand Osteoarthritis
Treatment of Erosive Digital Osteoarthritis by Transcutaneous Auricular Nerve Stimulation
Erosive hand osteoarthritis (EHOA) is a subtype of had osteoarthritis characterized by inflammation and pain, with subsequent burden.
- Trial name
- ADEPT (NCT03919279)
- Testing
- active tVNS
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke
Noninvasive Vagal Nerve Stimulation for Arm Recovery After Stroke
This study will find out whether electrical stimulation of a nerve called the "vagus" nerve is acceptable for patients undergoing physiotherapy for arm weakness after a stroke.
- Trial name
- NCT03170791
- Testing
- vagal nerve stimulation intervention
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Visually Induced Motion Sickness in Healthy Volunteers
Effect of Transcutaneous Vagal Nerve Stimulation on Reducing Visually Induced Motion Sickness in Healthy Volunteers
Nausea is a common and distressing experience that often precedes vomiting. Amongst symptoms emanating from the gastrointestinal (GI) tract nausea can be considered somewhat unique, as on one hand it represents a normal, highly…
- Trial name
- NCT02177890
- Testing
- Transcutaneous vagal nerve stimulation
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wingate Institute of Neurogastroenterology
Atrial Fibrillation
Vagal Nerve Stimulation for the Treatment of Persistent AF
The goal of this clinical trial is to answer the question whether a transcutaneous stimulation of a certain nerve (Nervus vagus) with a dedicated device reduces the recurrence of the heart rhythm disorder atrial fibrillation.
- Trial name
- VAST-AF (NCT05833373)
- Testing
- Vagal stimulation with the device tVNS from tVNS Technologies GmbH
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Krankenhaus Hetzelstift