Clinical trials: Transgender Persons
Alcohol Use Disorder
Improving Alcohol Use Disorder Treatment for Gender Minority Populations
Gender minority (GM; transgender and gender non-conforming) individuals experience disproportionately high rates of hazardous drinking and alcohol use disorder (AUD) and are an NIH-designated disparity population (NOT-MD-19-001).
- Trial name
- NCT05070793
- Testing
- Culturally adapted interpersonal psychotherapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- New York State Psychiatric Institute
Transgender, Gender Dysphoria in Adolescents and Adults
The Effect of Gender-affirmative Measures on Breast Perception in Trans Men
Breast dysphoria in transmasculine or genderdiverse individuals is a distinct psychological burden associated with depression, anxiety and suicidality.
- Trial name
- TRANSBREAST (NCT07252687)
- Testing
- quality of life questionnaire- iTransQoL, chest dysphoria measure
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University Innsbruck
Gender Dysphoria
Brain Health in Transgender Adults
The purpose of this study is to test whether and how a person's brain changes in the first few months after starting gender affirming hormone therapy (GAHT).
- Trial name
- NCT07624747
- Testing
- Magnetic Resonance Imaging, Cognition and Health Tests, Optional Exercise Test
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
HIV/AIDS, Health Knowledge, Attitudes, Practice
Evaluation of the Trans Women Connected Mobile App for Changes in Sexual Health-related Behavior Among Transgender Women
The study is a 2-arm cluster randomized controlled trial to be conducted with 450 trans women to assess the effectiveness of the Trans Women Connected mobile app.
- Conditions
- HIV/AIDS, Health Knowledge, Attitudes, Practice, STI
- Trial name
- TWC (NCT03897049)
- Testing
- Trans Women Connected, General Health App
- Where
- United States
- Volunteers
- 574 people, healthy volunteers welcome
- Sponsor
- ETR Associates
HIV Infections
(mo)BETTA Trial in Transwomen for Optimization of ART
The purpose of this study is to determine the safety and tolerability of a new HIV medication, bictegravir plus emtricitabine plus tenofovir alafenamide (B/FTC/TAF, 3 HIV medications combined into one pill) in HIV-infected…
- Trial name
- (mo)BETTA (NCT03348163)
- Testing
- B/FTC/TAF, Current ART
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- The University of Texas Health Science Center, Houston
HIV Prevention, Transgender Health
Study of Truvada for HIV Pre Exposure Prophylaxis Using Daily Directly Observed Therapy to Look at Potential Interactions Between Truvada and Hormone Therapy
Truvada (Emtricitabine or FTC and tenofovir disoproxil fumarate or TDF) has been approved for HIV prevention since 2012. Drug concentrations after receipt of oral Truvada for HIV Pre Exposure Prophylaxis (or PrEP) appeared to be…
- Trial name
- I-BrEATHe (NCT04050371)
- Testing
- 200 mg emtricitabine and 300 mg tenofovir disoproxil fumarate
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Transgender Women, Aids
Economic Navigation and Strengthening to Research Unrestricted Services for Transgender Women (ENTRUST)
The overall hypothesis is that stabilizing transgender women financially while providing them tailored counselling will increase their odds of them linking to substance use services, PrEP services if they do not have HIV, and…
- Conditions
- Transgender Women, Aids, Hiv
- Trial name
- NCT06202898
- Testing
- Baseline, ENTRUST, Control
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Central Florida
HIV, STIs
The South-East Asian Transgender Health Cohort
This is a prospective observational cohort study that will enroll 300 HIV-negative transgender people and 150 transgender people living with HIV from 4 community health centers in Thailand, Vietnam, and the Philippines.
- Conditions
- HIV, STIs, HCV
- Trial name
- SEATrans (NCT05454579)
- Where
- 5 sites in Philippines, Thailand and 1 more
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Institute of HIV Research and Innovation Foundation, Thailand
Sleep Disorder, Insulin Resistance
Sleep and IR in Transgender Adolescents
Disordered sleep is a health issue with significant impacts on physical and psychological well-being that has increased in prevalence, but its impact on transgender adolescents has not been fully quantified.
- Conditions
- Sleep Disorder, Insulin Resistance, Gender Dysphoria
- Trial name
- ATP (NCT05489159)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Duke University
Pre-Exposure Prophylaxis of HIV Infection
Pre-Exposure Prophylaxis Study of Lenacapavir in Cisgender Men, Transgender Women, Transgender Men, and Gender Nonbinary People at Risk for HIV Infection
The goal of this study is to evaluate the efficacy of the study drugs, lenacapavir (LEN) in preventing HIV infection, in participants ≥ 16 years of age who have condomless receptive anal sex with partners assigned male at birth…
- Trial name
- PURPOSE 2 (NCT04925752)
- Testing
- Oral Lenacapavir (LEN), F/TDF, Sub-cutaneous (SC) Lenacapavir (LEN)
- Where
- 93 sites in United States, Argentina and 6 more
- Volunteers
- 3,292 people, healthy volunteers welcome
- Sponsor
- Gilead Sciences
HIV Infections
Use of Amphetamine-type Stimulants & Its Relationship With HIV Incidence and Antiretroviral Adherence Among MSM and TG
There are two stages in the study. In Stage 1, 2000 Thai MSM, MSW and TGW/TGSW will be screened at the Thai Red Cross Anonymous Clinic (TRCAC) or Besides walk-in clients of TRCAC, potential participants could be referred to TRCAC…
- Trial name
- NCT03198962
- Where
- Thailand
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
Tobacco-Related Carcinoma
Evaluating Anti-Tobacco Message Effectiveness Among Lesbian, Gay, Bisexual, and Transgender Young Adults
This trial refines and evaluates anti-tobacco messages among lesbian, gay, bisexual, and transgender (LGBT) young adults at risk for the use of more than one tobacco product (polytobacco use).
- Trial name
- NCT05393869
- Testing
- Health communications
- Where
- United States
- Volunteers
- 2,849 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Gender Affirming Communication Skills
Simulated Conversation Training for Mental Healthcare Providers to Improve Care for Transgender and Gender Nonconforming Individuals
Phase I: Eligible participants (n=20) will be recruited to participate in a feasibility evaluation of the client intake module to be developed.
- Trial name
- NCT04820088
- Testing
- Computer based role play trianing
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- SIMmersion, LLC
Dementia, Caregiver Burnout
Equality in Caregiving: Facilitating Caregiver Mastery Among LGBT Caregivers of PLWD
The goal of this study is to adapt existing Savvy Caregiving Program (SCP) for lesbian, gay, bisexual, transgender (LGBT) caregivers of person living with dementia (PLWD).
- Trial name
- EIC (NCT04394260)
- Testing
- Savvy Caregiver Program via Remote Learning, Focus group
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University