Clinical trials: Transgenderism, active
Surgery, Larynx
Voice Outcome of Glottoplasty, Cricothyroid Approximation, Thyroplasty, and Chondrolaryngoplasty
The purpose of this study is to measure the short- and long-term voice outcome and outcome predictors of glottoplasty, cricothyroid approximation, thyroplasty, and chondrolaryngoplasty using a prospective non-randomized…
- Conditions
- Surgery, Larynx, Transgenderism, Gender Dysphoria
- Trial name
- NCT06439290
- Testing
- Phonosurgery, Mastectomy/breast augmentation
- Where
- 2 sites in Belgium
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- University Ghent
Transgenderism
Prospective Imaging Assessment of Perineo-pelvic Static's Evolution After Sexual Reassignment Surgery in MtF Transgender Patient, by Peno-scrotal Inversion Vaginoplasty Technique (TRANSPELV)
The research consists of adding to the usual MtF transgender patient undergoing vaginoplasty care course, static and dynamic perineo-pelvic MRI before, and at 6 and 24 months.
- Trial name
- TRANSPELV (NCT06093724)
- Testing
- Static and dynamic perineo-pelvic MRI
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Limoges
Transgenderism, Gender Dysphoria
Pubertal Blockade and Estradiol Effects on Cardiometabolic Health for Transitioning Youth
To evaluate the effect of estradiol with or without a prior gonadotropin releasing hormone analogue on insulin sensitivity and vascular function in transgender females compared to cisgender controls.
- Conditions
- Transgenderism, Gender Dysphoria, Insulin Sensitivity
- Trial name
- PUBERTY (NCT04596592)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Colorado, Denver
Transgenderism
Transgender Men, Non-binary Persons and Testosterone Treatment BODY IDENTITY CLINIC
The aim of this study is to investigate transgender men and non-binary persons before and during testosterone treatment. The study will focus on: Cardiovascular status Muscle strenght and power Aggression and quality of life…
- Trial name
- NCT04254354
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Marianne Andersen
Transgenderism, Insulin Sensitivity/Resistance
Puberty Suppression and Cardiometabolic Health
This observational study will evaluate the effect of puberty suppression on insulin sensitivity, metabolic rate and vascular health among transgender female youth at baseline and 6 months after initiation of a gondoatropin…
- Conditions
- Transgenderism, Insulin Sensitivity/Resistance, Endothelial Dysfunction, Vascular Stiffness
- Trial name
- NCT04482374
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Colorado, Denver
Transgender, Transgenderism
Cardiometabolic Health in Transgender Males
Transgender individuals are those with a gender identity opposite the sex they were assigned at birth. Approximately 1% of the population is transgender, equating to ~60,000 transgender Wisconsinites.
- Trial name
- NCT04977765
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Transgenderism, Reproductive Issues
Androgen Effects on the Reproductive Neuroendocrine Axis, 2025 Version
This research study investigates whether male-level exogenous androgens inhibit the reproductive neuroendocrine axis in otherwise healthy (non-PCOS) females.
- Trial name
- NCT07092527
- Testing
- Testosterone Cypionate 50 milligrams per millileter (mg/mL) Injectable Solution
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Gender Dysphoria, Gender Dysphoria, Adult
Metoidioplasty and Phalloplasty Surgery Decision Making
The goal of this clinical trial is to test a new online tool designed to provide clear and understandable information to help individuals considering Metoidioplasty and Phalloplasty Surgeries (MaPS) make informed decisions The…
- Conditions
- Gender Dysphoria, Gender Dysphoria, Adult, Gender Incongruence, Transgenderism
- Trial name
- MaPS (NCT06565663)
- Testing
- MaPS Decision Aid
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Lower Urinary Tract Symptoms, Transgenderism
Lower Urinary Tract Symptoms in Transmasculine Patients Undergoing Metoidioplasty and Their Acceptability of Pelvic Floor Muscle Training Assessed by a Pelvic, Obstetric and Gynaecological Physiotherapist
Lower urinary tract symptoms in transmasculine patients undergoing metoidioplasty and their acceptability of pelvic floor muscle training assessed by a Pelvic, Obstetric and Gynaecological Physiotherapist.
- Trial name
- LUTS-POGP (NCT06956989)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Transsexualism, Transgenderism
Effects of Cross-sex Hormone Therapy on Eating Behavior, Metabolism, Energy Balance and Cardiovascular System
Current study aims to characterize five highly interconnected physiological systems in patients undergoing cross-sex hormone therapy - namely glucose and lipid metabolism, energy balance, eating behavior, functional brain…
- Conditions
- Transsexualism, Transgenderism, Adiposity, Eating Behavior
- Trial name
- HHS (NCT04838249)
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Transgenderism
Feminizing Treatment in Transgender Women and Non-binary Persons
Cohort study in 100 transgender women treated with gender affirming hormone treatment. Follow up affter 1year, 3 years, 5 years and 10 years, Outcomes regarding cardiovascular effects of hormone treatment.
- Trial name
- BIC-Estrogen (NCT05169762)
- Testing
- standard treatment
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Odense University Hospital