Clinical trials: Transient
Neurologic Impairment by Opioids
Non-intrusive Detection of Temporary Neurologic Impairment by Opioids
The investigators aim to prove the feasibility of a non-invasive means to identify temporary neurological impairment resulting from the use of a commonly prescribed opioid by identifying an oculomotor biosignature associated with…
- Trial name
- NCT05489601
- Testing
- Oxycodone
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Zxerex Corporation
Acute Ischaemic Stroke, Transient Ischaemic Attack
THALES - Acute STroke or Transient IscHaemic Attack Treated With TicAgreLor and ASA for PrEvention of Stroke and Death
Study to investigate if the study drug ticagrelor and ASA is more effective than Placebo (inactive tablet) and ASA in preventing new stroke events
- Trial name
- THALES (NCT03354429)
- Testing
- Ticagrelor
- Where
- 387 sites in Argentina, Australia and 26 more
- Volunteers
- 11,016 people
- Sponsor
- AstraZeneca
Heavy Menstrual Bleeding
Juveena Hydrogel System Feasibility Study for Heavy Menstrual Bleeding (HMB)
This is a prospective, multicenter, single-arm interventional feasibility study to evaluate the safety and feasibility of the Juveena Hydrogel System for temporary control of heavy menstrual bleeding (HMB) in women with a history…
- Trial name
- NCT06634719
- Testing
- Juveena Hydrogel System
- Where
- 3 sites in United States
- Volunteers
- 13 people
- Sponsor
- Rejoni Inc.
Aortic Valve Stenosis, Endovascular Aortic Valve Replacement
Heart Leaflet Technologies Valve Study
The study will be conducted in patients who are undergoing surgical aortic valve replacement on cardiopulmonary bypass. Following surgical access of the native aortic valve and prior to removal of the valve, the native valve will…
- Trial name
- HLT (NCT00710775)
- Testing
- surgical replacement of the aortic stenotic valve
- Where
- Italy
- Volunteers
- 7 people
- Sponsor
- Centro Cardiologico Monzino
Stroke, Ischemic, Transient Ischemic Attack
Extracellular Vesicles and Dysregulated Coagulation in the Prediction of Stroke
Annually 100,000 strokes occur, placing stroke as the largest cause of disability in the UK. 90% of strokes are preventable, leading to national focus on programmes including "The National Stroke Programme" to act on preventing…
- Conditions
- Stroke, Ischemic, Transient Ischemic Attack, Coagulation Disorder
- Trial name
- PREDICT-EV (NCT05645081)
- Where
- United Kingdom
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Cwm Taf University Health Board (NHS)
Transient Ischemic Attack
Markers in the Diagnosis of TIA
MIND-TIA is primarily an observational diagnostic study that aims to evaluate the role of novel biomarkers in the diagnosis of Transient Ischemic Attack (TIA)in primary care.
- Trial name
- MIND-TIA (NCT01954329)
- Where
- Netherlands
- Volunteers
- 350 people
- Sponsor
- UMC Utrecht
Heart Failure Preserved Ejection Fraction, Pacing
Mechanistic Insights From Temporary Pacing in HFpEF
Heart failure with preserved ejection fraction (HFpEF) is characterised by impaired diastolic function. A recent clinical trial has demonstrated multiple beneficial outcomes in HFpEF patients receiving personalised accelerated…
- Trial name
- NCT06467266
- Testing
- Acute Haemodynamic Study
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Nasal Congestion Associated With the Common Cold
A Multicenter Study of Pseudoephedrine for the Temporary Relief of Nasal Congestion in Children With the Common Cold
This study is designed to confirm the effectiveness of single-ingredient pseudoephedrine in children for the temporary relief of nasal congestion due to the common cold, an indication described under 21 CFR 341.80(b)(1).
- Trial name
- NCT01744106
- Testing
- pseudoephedrine hydrochloride 30 mg tablets
- Where
- 11 sites in United States
- Volunteers
- 565 people
- Sponsor
- Perrigo Company
Chronic Liver Diseases (CLD)
Improvement of Transient Elastography Applicability and Diagnostic Accuracy to Identify Significant Fibrosis by Experienced Operators Using the M and XL Probe.
Transient elastography (TE)is the reference method to identify liver stiffness (LSM) but fails to obtain a measurement in 3% of cases and results are considered unreliable in 16%.
- Trial name
- NCT01900808
- Testing
- Trained operator with M probe., Experienced operator with M probe., Experienced operator with XL probe.
- Where
- Spain
- Volunteers
- 868 people
- Sponsor
- Parc de Salut Mar
Incomplete Closure of Lid, Parotis Tumor
External Lid Loading for the Temporary Treatment of the Paresis of the M. Orbicularis Oculi: a Clinical Note
The note re-introduces the external lid loading with the help of a lead weight for the temporary treatment of lagophthalmos. Although simple and effective, the technique is rarely used.Instead of wearing a monoculus, the patient…
- Conditions
- Incomplete Closure of Lid, Parotis Tumor, m. Orbicularis Oculi Paresis
- Trial name
- NCT01274689
- Testing
- individually tailored lead weight
- Where
- Germany
- Volunteers
- 152 people
- Sponsor
- Charite University, Berlin, Germany
Epilepsy, Non-Epileptic Seizure
Validation of Criteria for Identification of Epileptiform Discharges in EEG Recordings of Patients With Epilepsy
Electroencephalography (EEG) records electric activity of the brain using electrodes placed on the scalp. EEG is an important tool in the diagnostic work-up of patients with epilepsy.
- Trial name
- CIED (NCT03533374)
- Testing
- Electroencephalogram (EEG) and visual evaluation
- Volunteers
- 100 people
- Sponsor
- Sándor Beniczky
Stroke, Transient Ischemic Attack
Smartwatch-Guided Secondary Prevention After Stroke
After a first stroke or transient ischemic attack (TIA), the risk of recurrence is high in the weeks and months following the initial event.
- Trial name
- WATCH-STEP (NCT07640360)
- Testing
- Smartwatch-Guided Secondary Prevention after Stroke
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Brest
Orthodontic Appliance Complication
Effect of Local Subperiosteal Zoledronic Acid Injection on the Survival of Orthodontic Miniscrews
Background: Orthodontic miniscrews are widely used as temporary anchorage devices; however, failure remains a clinical concern. Bisphosphonates may enhance bone stability, but evidence on their local application is limited.
- Trial name
- NCT07546058
- Testing
- Zoledronic Acid, Normal saline (0.9% sodium chloride)
- Where
- Syria
- Volunteers
- 68 people
- Sponsor
- Latakia University
Ischemic Stroke, Transient Ischemic Attack
Prognostic Value of Cardiac and Renal Markers in Ischemic Stroke and Transient Ischemic Attack
Patients with stroke or transient ischemic attack (TIA) are at high risk of poor outcome, recurrence of cardiovascular events or vascular death.Until now, no reliable predictive biological marker could be identified in the acute…
- Trial name
- ABC-AVC (NCT00479518)
- Where
- 3 sites in France
- Volunteers
- 159 people
- Sponsor
- University Hospital, Tours
Acute Ischemic Stroke, Transient Ischemic Attack
Rivaroxaban Acute Stroke Safety Study
Atrial fibrillation is a common cardiac arrhythmia and a major risk for ischemic stroke. Furthermore the risk of stroke is higher in the first month after transient ischemic attack (TIA)/stroke.
- Trial name
- RASS (NCT02279940)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Alberta
Carotid Artery Disease, Carotid Artery Stenosis
Neurological Outcome With Carotid Artery Stenting
The purpose of this study is to determine how well patients undergoing carotid artery angioplasty and/or stent-supported angioplasty for the treatment of carotid artery stenosis will perform on a battery of tests to assess brain…
- Conditions
- Carotid Artery Disease, Carotid Artery Stenosis, Stroke, Transient Ischemic Attack
- Trial name
- CAS (NCT00597974)
- Testing
- Angioplasty, Stent, Neurological and neuropsychological evaluations
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Columbia University
Benign Prostatic Hyperplasia (BPH)
Study to Assess the Efficacy of Medi-Tate iTind Device
The study will include an implantation of the iTind device and 4 follow up visits up to 12 months after the implantation.
- Trial name
- NCT02145208
- Testing
- TIND System
- Where
- 8 sites in Belgium, Italy and 3 more
- Volunteers
- 81 people
- Sponsor
- Medi-Tate Ltd.
Residents's Frailty in Temporary Accommodation, Residents's Quality of Life in Temporary Accommodation
Effectiveness of the Jeanne et Léon Program® on the Residents's Frailty in Temporary
The management of frailty is a difficulty in the Temporary Accommodation Residences. Frailty represents a risk of reducing the activities of the elderly person.
- Trial name
- FRAQOL (NCT05659706)
- Testing
- cognitive evaluations and non cognitive evaluations
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jeanne et Leon Developpement
Midface Volume Deficit
To Evaluate the Performance and Safety of YVOIRE Volume Plus for Improvement of Mid-face Volume
A Study to Evaluate the Performance and Safety of YVOIRE volume plus for Temporary Improvement of Mid-face Volume
- Trial name
- NCT04784299
- Testing
- YVOIRE volume plus, Restylane Lyft with Lidocaine
- Where
- Germany
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- LG Chem
Cardiac Failure
Temporary Epicardial Cardiac Resynchronisation.
This trial will investigate the clinical and haemodynamic effects of temporary biventricular pacing after cardiac surgery. Subjects with poor left ventricular systolic function will receive either temporary biventricular pacing…
- Trial name
- NCT01027299
- Testing
- Biventricular pacing
- Where
- 2 sites in United Kingdom
- Volunteers
- 31 people
- Sponsor
- Cardiff and Vale University Health Board
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