Clinical trials: Transient
Stroke, Transient Ischemic Attack
"Carotid Web Incidence and Radiological Classification, Determination of Its Relationship With Ischemic Stroke"
In our research, we aim to increase awareness on this issue by classifying the frequency of carotid webs and their radiological classification; Evaluating the clinical data and vascular risk factors of carotid web cases and…
- Conditions
- Stroke, Transient Ischemic Attack, Carotid Artery Diseases
- Trial name
- NCT06058507
- Testing
- CT angiography
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Suleyman Demirel University
Pelvic Organ Prolapse
R&D Supporting Pilot Study for the Assessment of the Safety and Effectiveness of the ProVATE (ProTIPI) Vaginal Pessary
The study includes five (5) main stages: Screening, Enrollment, Size fitting, Usage and Termination. Subject screening will be held during visit one (1) and visit two (2) at the clinic.
- Trial name
- NCT02239133
- Testing
- ProVATE vaginal pessary
- Where
- 3 sites in Israel
- Volunteers
- 44 people
- Sponsor
- ConTIPI Medical
Stroke, Hypertension
DELPHI in Subjects at Risk for Stroke and Dementia
The DELPhi system is a software device that is used for the noninvasive evaluation of brain plasticity and connectivity. The DELPhi software uses EEG and TMS devices as accessories.
- Conditions
- Stroke, Hypertension, Diabete Mellitus, Dyslipidemias
- Trial name
- NCT03884647
- Testing
- DELPhI system
- Where
- 4 sites in United States, Israel
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- QuantalX Neuroscience
Transient Insomnia
An Investigational Study to Assess Efficacy and Pattern of Use of SM-1 in Subjects With a History of Transient Insomnia
The purpose of this study is to assess the efficacy and pattern of use of the combination drug product SM-1 in adults who sometimes have difficulty in falling asleep or staying asleep, but who do not have chronic insomnia.
- Trial name
- NCT03338764
- Testing
- SM-1
- Sponsor
- Sequential Medicine Ltd
Implant Failure, Infection
Use of Biocompatible Thermoplastic Impregnated With Vancomycin as a Temporary Orthopedic Spacer
With the progressive aging of the population and the rising number of individuals with degenerative diseases, there has been an increasing indication for joint replacement arthroplasties as a treatment for osteoarthritis in major…
- Trial name
- ORTOPLA (NCT07031999)
- Testing
- PLA spacer
- Volunteers
- 30 people
- Sponsor
- Hospital Universitario Evangelico de Curitiba
Ischemic Stroke, TIA
Stroke Card Long-term Follow-Up
We undertook the STROKE-CARD trial (NCT02156778) between 2014 and 2018 with follow-up until 2019 to evaluate the efficacy of the Post-Stroke disease-management program STROKE-CARD care.
- Trial name
- NCT04205006
- Where
- 2 sites in Austria
- Volunteers
- 1,000 people
- Sponsor
- Medical University Innsbruck
TIA
SpecTRA; An Observational Study of the Verification of Protein Biomarkers in Transient Ischemic Attack.
A multi-protein test using mass spectrometry (MS) for multiplexed protein quantitation is being developed. This test and the accompanying decision-aid software will provide Transient Ischemic Attack (TIA) results rapidly for a…
- Trial name
- NCT03050099
- Testing
- Non-Interventional Study
- Where
- 2 sites in Canada
- Volunteers
- 560 people
- Sponsor
- Andrew Penn
Cerebrovascular Stroke, Atrial Fibrillation
Prediction and Detection of Occult Atrial Fibrillation in Patients After Acute Cryptogenic Stroke and TIA
PROACTIA is a prospective, event-driven observational study. It aims to propose a composite scoring system in order to evaluate the risk of paroxysmal atrial fibrillation (PAF) in patients after acute cryptogenic stroke and…
- Trial name
- PROACTIA (NCT02725944)
- Testing
- Implantation of ICRM
- Where
- Norway
- Volunteers
- 251 people
- Sponsor
- University Hospital, Akershus
Patent Foramen Ovale, Cryptogenic Stroke
Long-term Outcomes After Percutaneous Patent Foramen Ovale Closure (Severance PFO Registry)
Patent foramen ovale (PFO) is a congenital interatrial communication present in about one quarter of the general population and is recognized as a major cause of cryptogenic stroke.
- Conditions
- Patent Foramen Ovale, Cryptogenic Stroke, Transient Ischemic Attack Due to Embolism, Atrial Fibrillation
- Trial name
- NCT07724171
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Yonsei University
Epigastric Pain, Retrosternal Pain
Transient Receptor Potential Vanilloid One (TRPV1) Receptor Expression in Children With Retrosternal Pain
We would like to evaluate the changes in nerve innervation and TRPV1 receptor expression along with microscopic changes associated with heart burn and abdominal pain
- Conditions
- Epigastric Pain, Retrosternal Pain, Esophagitis, Gastrointestinal Symptoms
- Trial name
- TRPV1 (NCT00677378)
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Medical College of Wisconsin
Septic Shock
TIMP2*IGFBP7 and Transient AKI
Patients with septic shock in the intensive care unit have a high risk to develop acute kidney injury (AKI) and AKI is an independent risk factor of mortality.
- Trial name
- BIOCHECK (NCT03472079)
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Biliary Atresia, Alagille Syndrome
FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE)
Noninvasive monitoring of liver fibrosis is an unmet need within the clinical management of pediatric chronic liver disease. While liver biopsy is often used in the initial diagnostic evaluation, subsequent biopsies are rarely…
- Conditions
- Biliary Atresia, Alagille Syndrome, Alpha1 Anti-Trypsin Deficiency, Portal Hypertension
- Trial name
- FORCE (NCT02922751)
- Testing
- Liver Stiffness Measurement (LSM)
- Where
- 13 sites in United States, Canada
- Volunteers
- 552 people
- Sponsor
- Arbor Research Collaborative for Health
Leiomyoma, Laparoscopic Myomectomy
Temporary Clipping of the Uterine Arteries During Laparoscopic Myomectomy
The aim is to verify, whether intraoperative temporary clipping of the uterine vessels with vascular clips can reduce blood loss significantly.
- Trial name
- NCT01530802
- Testing
- clipping of uterine arteries during laparoscopic myomectomy
- Where
- 2 sites in Germany
- Volunteers
- 166 people
- Sponsor
- Charite University, Berlin, Germany
Ischaemic Attack, Transient
Safety Escalating Repeat IV, in Stroke Patients
The purpose of this study is to is to test increasing repeat doses of GSK249320 compared to placebo in patients with stroke.
- Trial name
- MAG111539 (NCT00833989)
- Testing
- GSK249320
- Where
- 15 sites in United States, Canada and 1 more
- Volunteers
- 42 people
- Sponsor
- GlaxoSmithKline
Sickle Cell Disease, Sickle Cell Anemia
Feasibility and Preliminary Efficacy of Acceptance and Commitment Therapy (ACT) for Sleep Disturbances in Adults With Sickle Cell Disease (SCD)
Research Type: Clinical Trial Background: People with sickle cell disease (SCD) have many health challenges. Also, they often have trouble sleeping.
- Conditions
- Sickle Cell Disease, Sickle Cell Anemia, Insomnia, Sleeplessness
- Trial name
- NCT05457790
- Testing
- ACT Intervention, Waitlist
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- National Cancer Institute (NCI)
Paralytic Lagophthalmos
A Real-Time Magnetic Device Prototype for Temporary Management of Paralytic Lagophthalmos
To develop a real-time wearable device based on the principle of magnetic force for temporary management of lagophthalmos, and evaluate its efficacy and safety, including synchronous blinks and eye closure, blurred vision…
- Trial name
- NCT03848260
- Testing
- Magnetic device prototype
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- E-DA Hospital
Low Anterior Resection Syndrome
Anal Dilatation Plus Probiotics Before Ileostomy Reduction for Low Anterior Resection Syndrome
This is randomized, phase 2 trial in patients with rectal cancer undergoing sphincter-preserving proctectomy and temporary ileostomy, to explore the effects of anal dilatation plus probiotics administered per anus before…
- Trial name
- PILLARS (NCT04688242)
- Testing
- Anal dilatation per anus, administration of probiotics (Clostridium butyricum TO-A; Bacillus mesentericus TO-A; Streptococcus faecalisT-110) per anus
- Where
- 2 sites in China
- Volunteers
- 164 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Carotid Artery Diseases, Stroke
Carotid Artery Disease After Stroke (CADAS).
Stroke is a significant medical problem with 150,000 events occurring per year in the UK and incurring healthcare costs of £4 billion per year.
- Conditions
- Carotid Artery Diseases, Stroke, Transient Ischemic Attack
- Trial name
- CADAS (NCT03721523)
- Testing
- 3 Dimensional tomographic Ultrasound, Platelet Aggregometry
- Where
- 3 sites in United Kingdom
- Sponsor
- University of Manchester
Burns
Human Amniotic Versus Synthetic Membrane as a Transient Skin Cover for Pediatric Burns
This is a randomised trial that aims to evaluate whether a transient skin cover made out of human amniotic membranes is effective in managing burns among pediatric patients.
- Trial name
- NCT02904941
- Testing
- Amniotic Membrane Dressing, Synthetic Dressing, Standard Wound Care
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- Universidad de Valparaiso
Acute Ischemic Stroke, Large Vessel Occlusion
Proximal TEmporary oCclusion Using Balloon Guide Catheter for Mechanical Thrombectomy
A multi-center, prospective, randomized, open-label, blinded endpoint assessment (PROBE) clinical trial of endovascular treatment among selected AIS.
- Conditions
- Acute Ischemic Stroke, Large Vessel Occlusion, Thrombectomy, Thrombosis
- Trial name
- PROTECT-MT (NCT05592054)
- Testing
- Balloon guide catheters (BGCs), Standard guide catheter
- Where
- China
- Volunteers
- 329 people
- Sponsor
- Changhai Hospital
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