Clinical trials: Transient
Liver Diseases
Development of a New Method for Liver Stiffness Measurement Using FibroScan
This is an European, prospective, interventional, multicenter clinical investigation that will take place in 2 French sites. 153 adults patients will be included.
- Trial name
- M148 (NCT06519331)
- Testing
- Research FibroScan (FS)
- Where
- 2 sites in France
- Volunteers
- 153 people
- Sponsor
- Echosens
Parkinsons Disease With Dementia
A Study to Evaluate Temporary Blood Brain Barrier Disruption in Patients With Parkinson's Disease Dementia
The goal of this prospective, non-randomized, single-arm, feasibility study is to develop data to evaluate the safety and initial efficacy of this treatment (temporary disruption of the BBB) using this ExAblate Model 4000 Type 2…
- Trial name
- NCT03608553
- Testing
- MR Guided Focused Ultrasound
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- InSightec
Subarachnoid Hemorrhage, Aneurysm
Lycopene Following Aneurysmal Subarachnoid Haemorrhage
In this study the investigators wish to explore the potential neuroprotective effects of acute oral supplementation of lycopene, a natural anti-oxidant derived from tomatoes, on cerebral vasospasm and autoregulation, and examine…
- Trial name
- LASH (NCT00905931)
- Testing
- Lycopene
- Where
- United Kingdom
- Volunteers
- 124 people
- Sponsor
- University of Cambridge
Temporomandibular Joint Disorders
Temporary Hydrostatic Splint Therapy and Its Effects on Occlusal Forces
The goal of this non-randomized controlled trial is to analyze and compare occlusal force distribution patterns using T-Scan III before and after hydrostatic splint therapy on both healthy subjects and subjects with…
- Trial name
- NCT05827263
- Testing
- T-Scan occlusal recording No. I, Usage of the hydrostatic appliance, T-Scan occlusal recording No. II
- Where
- Lithuania
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Stroke, Transient Ischemic Attack
Smoking Cessation Intervention After Stroke or Transient Ischaemic Attack.
Patients with stroke or transient ischemic attach should receive advise on smoking cessation. It is however unknown if an intensive smoking cessation program is better than ordinary advise on smoking cessation during…
- Trial name
- NCT00228098
- Testing
- Smoking cessation
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Odense University Hospital
Transient Elastography, MASLD
Hepatic Elastography-Enhanced Lifestyle Modification in MASLD
The 2022 National Health Survey in Thailand revealed a substantial rise in obesity and metabolic dysfunction-associated steatotic liver disease (MASLD).
- Conditions
- Transient Elastography, MASLD, BMI, Metabolic Syndrome
- Trial name
- NCT06826807
- Testing
- Regular monitoring with transient elastography
- Where
- Thailand
- Volunteers
- 92 people
- Sponsor
- Mahidol University
Morbid Obesity
Efficacy of Preoperative Intra Gastric Balloon in Morbidly Obese Patients Selected for Gastric By-pass
To demonstrate, during a prospective randomized medico-economic study, in morbidly obese patients (BMI > 45 kg/m²) selected for a laparoscopic gastric by-pass that, in comparison to usual care, a temporary intra-gastric balloon…
- Trial name
- BIGPOM (NCT00504036)
- Testing
- inflatable intra-gastric balloon
- Where
- France
- Volunteers
- 314 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healthy
Study of the Diaphragmatic Function by Transient Elastography (ELASTODIAPH)
The study of diaphragmatic function is usually measured by the pressures and volumes generated by contraction of the diaphragm, which is often difficult (cumbersome technique, difficulty to obtain a perfect cooperation of the…
- Trial name
- ELASTODIAPH (NCT03313141)
- Testing
- Ultrasound
- Where
- France
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Reflux Episodes
TLESR-impedance Study in Patients
The purpose of the study is to compare frequency and content of reflux episodes in patients with gastroesophageal reflux disease.
- Trial name
- NCT00743444
- Testing
- AZD3355
- Volunteers
- 27 people
- Sponsor
- AstraZeneca
Acute Ischemic Stroke, Transient Ischemic Attack (TIA)
A Study on BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel
The purpose of this clinical study is to determine whether the addition of an oral Factor XIa Inhibitor to Aspirin and Clopidogrel is more effective than standard therapy in secondary stroke prevention.
- Trial name
- AXIOMATIC-SSP (NCT03766581)
- Testing
- BMS-986177, Clopidogrel, Aspirin
- Where
- 424 sites in United States, Argentina and 27 more
- Volunteers
- 2,366 people
- Sponsor
- Bristol-Myers Squibb
Diastolic Dysfunction, Neonatal Encephalopathy
Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography
The goal of this single-centre longitudinal observational study is to create reference values for diastolic function parameters in neonates born at 35 weeks' gestation or above, and to assess the influence of pre-defined…
- Conditions
- Diastolic Dysfunction, Neonatal Encephalopathy, Small for Gestational Age at Delivery, Transient Tachypnea of the Newborn
- Trial name
- DiFuSE (NCT06200519)
- Where
- Ireland
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University College Cork
Delirium, Ischemic Stroke
Post-stroke Delirium Screening
For a long time, delirium was considered a merely temporary dysfunction of the brain. Today, it is established that it is a brain disease associated with network dysfunction, neuroinflammation and impaired transmitter homeostasis…
- Conditions
- Delirium, Ischemic Stroke, Transient Ischemic Attack
- Trial name
- PSD Screen (NCT03930719)
- Testing
- Stroke screening tools
- Where
- Germany
- Volunteers
- 141 people
- Sponsor
- University Medicine Greifswald
Stroke
Post-Stroke Secondary Prevention With Digital Monitoring
Stroke is the second leading cause of death and a major cause of disability worldwide. In 2019, Disability-Adjusted Life-Years (DALYs) related to stroke was estimated to have reached 143 million.
- Trial name
- PSDM (NCT06837311)
- Testing
- Ecological Momentary Assessment (EMA), Biological assessment, Psychological examination and Substance Use symptomatology
- Where
- France
- Volunteers
- 388 people
- Sponsor
- University Hospital, Bordeaux
Presbyopia
Safety & Efficacy of Pilocarpine Eye Solutions for Temporary Improvement of Near Vision in Presbyopic Adults
Volunteer participants are evaluated for eligibility during a Screening Visit; those meeting study inclusion/exclusion criteria are scheduled for 3 treatment visits.
- Trial name
- VISION-1 (NCT04657172)
- Testing
- Pilocarpine Ophthalmic
- Where
- 9 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Eyenovia Inc.
Transient Ischemic Attack
Standardized Physical Activities Measured by Accelerometers
STANDARDIZED PHYSICAL ACTIVITIES MEASURED BY ACCELEROMETERS Background and aims: Physical activity may be assessed by several different methods.
- Trial name
- NCT01629342
- Testing
- Standardized activities
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hillerod Hospital, Denmark
Liver Fibrosis
Prospective Comparison Between TE, SWE and MRE (FULLFIBRO01)
The main purpose of the present study is to compare the diagnostic performance of three non-invasive stiffness imaging methods (TE, SWE and MRE) in a consecutive cohort of patients with chronic viral C hepatitis or co-infected by…
- Trial name
- FULLFIBRO01 (NCT03293953)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Ente Ospedaliero Ospedali Galliera
Transient Hypothyroxinemia
A Randomised Controlled Trial of Iodide Supplementation in Preterm Infants Follow-up at 2 Years
The purpose of this trial is to determine whether iodide supplementation of neonates born under 31 weeks gestation improves neurodevelopment measured at two years of age.
- Trial name
- I2S2 (NCT00638092)
- Testing
- sodium iodide, Sodium Chloride
- Where
- 19 sites in United Kingdom
- Volunteers
- 1,275 people
- Sponsor
- University of Oxford
Transient Severe Arterial Phase Motion
Eovist vs. Dotarem Healthy Volunteer MRI
The purpose of this study is to evaluate changes in volunteer breath-holding capacity in response to gadoxetate disodium (Eovist) administration, compared with saline, and gadoterate dimeglumine (Dotarem).
- Trial name
- NCT02431598
- Testing
- gadoxetate disodium, gadoterate dimeglumine, Saline
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Duke University
Aging
Transient Receptor Potential Channels
Neurovascular signaling in the skin associated with stimulation of the transient receptor potential (TRP) channels. These channels are stimulated by both temperature and naturally occurring bioactive agents found in mint, chili…
- Trial name
- TRP (NCT06444594)
- Testing
- TRPM8 Agonist, TRPV1 Agonist, TRPV4 Agonist
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Penn State University
Abdominal Aortic Aneurysm, Coronary Heart Disease NOS
Social Deprivation and Initial Presentation of 12 Cardiovascular Diseases: a CALIBER Study
Study of heterogeneity in associations between social deprivation and the initial presentation of 12 cardiovascular diseases.
- Conditions
- Abdominal Aortic Aneurysm, Coronary Heart Disease NOS, Unheralded Corronary Death, Intracerebral Haemorrhage
- Trial name
- IP4 (NCT01937065)
- Testing
- No treatment
- Where
- United Kingdom
- Volunteers
- 1,937,360 people, healthy volunteers welcome
- Sponsor
- University College, London
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