Clinical trials: Transient
Stroke, Ischemic Attack, Transient
Performing a Low-dose, Whole-body Angiography as the First Element of an Imaging Assessment Following Stroke / TIA
The main objective of this study is to compare two post-stroke/TIA (transient ischemic attack) imaging strategies in terms of the number of clinically important (i.e.
- Trial name
- VASCU (NCT02662751)
- Testing
- Routine Imaging Assessment, LDWBA first (CT scan)
- Where
- 2 sites in France
- Volunteers
- 260 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Stroke, Ischemic, Transient Ischemic Attack
Liverpool-Heart and BRain Project Stroke Cohort
What research question is being addressed? Can improve the prediction of adverse outcomes be improved for people following a stroke to optimise their treatment and care? How is it of relevance and importance to patients and…
- Trial name
- L-HARP (NCT05132465)
- Where
- United Kingdom
- Volunteers
- 1,655 people
- Sponsor
- University of Liverpool
Borderline Personality Disorder
Magnetic Seizure Therapy for the Treatment of Borderline Personality Disorder
Suicide is a major public health crisis for which effective new interventions are needed. An innovative new brain stimulation technique called magnetic seizure therapy (MST) shows promise for treating suicidal thinking in…
- Trial name
- NCT03361826
- Testing
- MagPro MST with Cool TwinCoil, DBT
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- Centre for Addiction and Mental Health
Transient Ischemic Attack
Post-emergency Management of Patients With Transient Ischemic Attack
A transient ischemic attack (TIA) is a momentary neurological dysfunction due to a brief cessation of blood flow to a region of the brain, resulting in typical signs of stroke (hemiplegia, aphasia, dysarthria), but whose clinical…
- Trial name
- NCT06170034
- Testing
- Satisfaction questionnaire, Medical care questionnaire
- Where
- France
- Volunteers
- 49 people
- Sponsor
- Centre Hospitalier Henri Duffaut - Avignon
Ischemic Stroke, Transient Ischemic Attack
StAtins in Frail OldEr Patients with Ischemic Stroke or Transient Ischemic Attack - the Randomized Controlled Trial
Two Dutch guidelines (Stroke and Cardiovascular Risk Management) provide conflicting advice on optimal statin treatment in older patients.
- Trial name
- SAFEST - RCT (NCT06785727)
- Testing
- Statin (atorvastatin, fluvastatin, pravastatin, rosuvastatin or simvastatin)
- Volunteers
- 612 people
- Sponsor
- Prof. dr. Nathalie van der Velde
Atrial Fibrillation (AF), Hypertension
Integrated Approach in Frail Older People with Atrial Fibrillation
The study will verify if a structured multidisciplinary approach (called iABC), aimed to improve the appropriate management of elderly AF patients with multimorbidity (the i-ABC group), would provide a clear evidence of an…
- Conditions
- Atrial Fibrillation (AF), Hypertension, Coronary Arterial Disease (CAD), Heart Failure
- Trial name
- AFFIRMO (NCT06775028)
- Testing
- iABC platform use
- Where
- 50 sites in Bulgaria, Denmark and 4 more
- Volunteers
- 1,250 people
- Sponsor
- Heart Care Foundation
Ischemic Stroke, TIA (Transient Ischemic Attack)
Evaluation of the Efficacy of Novel Biomarkers in Predicting Clopidogrel Resistance in Patients with Ischemic Stroke
The goal of this observational study is to explore the potential efficacy of related biomakers in predicting clopidogrel resistance in patients with ischemic stroke. To be specific : 1.
- Conditions
- Ischemic Stroke, TIA (Transient Ischemic Attack), Clopidogrel Resistance
- Trial name
- NCT06753149
- Volunteers
- 800 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Alzheimer's Disease, Small Vessel Disease White Matter Hyperintensities Subtype
Amyloid and Glucose PET Imaging in Alzheimer and Vascular Cognitive Impairment Patients With Significant White Matter Disease
The prevalence of both Alzheimer's Disease (AD) and stroke doubles each decade over 65 years old. Both are major causes of dementia, currently estimated to affect 46 million people worldwide.
- Conditions
- Alzheimer's Disease, Small Vessel Disease White Matter Hyperintensities Subtype, Vascular Cognitive Impairment
- Trial name
- MITNEC C6 (NCT02330510)
- Where
- 8 sites in Canada
- Volunteers
- 80 people
- Sponsor
- Dr. Sandra E Black
Ischemic Stroke, Cryptogenic, Transient Ischemic Attack
Smartwatches for Detection of Atrial Fibrillation (AFib) in Secondary Prevention of Cryptogenic Stroke
Scientific Background: In secondary prevention of ischemic stroke, detection of atrial fibrillation (AFib) and subsequent anticoagulation therapy reduce the risk of recurrent stroke by approximately 60%.
- Conditions
- Ischemic Stroke, Cryptogenic, Transient Ischemic Attack, Atrial Fibrillation
- Trial name
- WATCH AFib (NCT06005233)
- Testing
- Smartwatch
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- Technical University of Munich
Intracranial Hemorrhage
Registration of Idarucizumab for Patients with IntraCranial Hemorrhage
This multicenter, prospective, observational, non-interventional study investigates patients with intracranial hemorrhage under effective anticoagulation with dabigatran or vitamin-K antagonist (VKA).
- Trial name
- RIC-ICH (NCT04062097)
- Testing
- Dabigatran Etexilate Oral Capsule [Pradaxa], Idarucizumab 2.5 GM/50 ML Intravenous Solution [PRAXBIND], Vitamin K antagonist
- Where
- 33 sites in Germany
- Volunteers
- 104 people
- Sponsor
- University Hospital, Essen
Transient Ischemic Attack (TIA)
Canadian TIA Score Versus ABCD2 Score in Risk Stratification of Transient Ischemic Attack (TIA)
This study aims to evaluate the superiority of a clinical score (Canadian TIA score) compared to the currently more widely used score in clinical practice (ABCD2 score) in stratifying the risk of stroke or carotid…
- Trial name
- NCT06718075
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Coronary Disease, Myocardial Infarction
Chronical Illness-related Limitations of the Ability to Cope with Rising Temperatures: an Observational Study, 2nd Wave
The CLIMATE-II Observational Study examines to what extent chronically ill patients experience adverse health effects because of heat and whether the patients' specific health behavior, somatosensory amplification, risk and…
- Conditions
- Coronary Disease, Myocardial Infarction, Heart Failure, Arrhythmias, Cardiac
- Trial name
- CLIMATE-II (NCT06407154)
- Where
- Germany
- Volunteers
- 578 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Transient Ischemic Attack, Ischemic Stroke
Philippine Neurological Association One Database - Stroke
This is a pragmatic, multi-center, prospective, observational, non-interventional study and standing database of patients hospitalized for transient ischemic attack (TIA) or stroke in the 11 accredited adult neurology training…
- Conditions
- Transient Ischemic Attack, Ischemic Stroke, Intracerebral Hemorrhage, Subarachnoid Hemorrhage
- Trial name
- PNA1DB-Stroke (NCT04972058)
- Where
- 11 sites in Philippines
- Volunteers
- 14,800 people
- Sponsor
- Philippine Neurological Association
Ischemic Stroke, Transient Ischemic Attack
Multiomics Targeting Microbiome Associated Changes in Stroke Patients (StrokeMicroBiomics)
Preclinical research has established a convincing connection between changes in the gut microbiota composition and stroke outcome. However clinical data on the gut-brain axis, and its chronic characteristics, is sparse.
- Trial name
- SMB (NCT04315922)
- Testing
- Microbiome and Plasma Characterisation
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Hip Effusion, Septic Arthritis
Accuracy of Pediatric Emergency Medicine Providers in Diagnosing Hip Effusions Using Point of Care Ultrasound
The purpose of this study is to determine if pediatric emergency medicine providers can accurately diagnose a hip effusion using point-of-care ultrasound (POCUS) compared to radiology ultrasound (RADUS).
- Conditions
- Hip Effusion, Septic Arthritis, Transient Synovitis, Hip
- Trial name
- NCT05971745
- Where
- 6 sites in United States, Australia
- Volunteers
- 161 people
- Sponsor
- Connecticut Children's Medical Center
Acute Stroke, Transient Ischemic Attack
Motivational Interviewing for Stroke
Motivational interviewing (MI) is a style of communication designed to elicit a person's own reasons for change to drive commitment toward a goal.
- Trial name
- NCT06195007
- Testing
- Motivational Interview
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Florida
Stroke, Ischemic, Transient Ischemic Attack
Extracellular Vesicles and Dysregulated Coagulation in the Prediction of Stroke
Annually 100,000 strokes occur, placing stroke as the largest cause of disability in the UK. 90% of strokes are preventable, leading to national focus on programmes including "The National Stroke Programme" to act on preventing…
- Conditions
- Stroke, Ischemic, Transient Ischemic Attack, Coagulation Disorder
- Trial name
- PREDICT-EV (NCT05645081)
- Where
- United Kingdom
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Cwm Taf University Health Board (NHS)
Carotid Stenosis, Stroke
Structural Stability of Carotid Plaque and Symptomatology
The purpose of the research is to understand structural plaque abnormalities that make a carotid plaque unstable and brake off (embolize) which would help to predict and treat individuals who are likely to suffer not only classic…
- Conditions
- Carotid Stenosis, Stroke, Carotid Artery Plaque, Transient Ischemic Attack
- Trial name
- NCT02476396
- Testing
- Carotid Endarterectomy or Stenting
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- University of Wisconsin, Madison
Carotid Artery Stenosis, Head and Neck Cancer
Carotid Artery Stenosis and Ischemic Cerebrovascular Events After Radiotherapy in Patients With Head and Neck Cancer
The study had a cross-sectional design and included patients with HNC involving the oral cavity, pharynx, larynx, nasal cavity, or salivary glands who recieve RT.
- Conditions
- Carotid Artery Stenosis, Head and Neck Cancer, Radiation Therapy, Transient Ischemic Attack
- Trial name
- RT-CASinHNC (NCT06556979)
- Testing
- Radiotherapy
- Where
- Thailand
- Volunteers
- 907 people
- Sponsor
- Chulabhorn Royal Academy
Ischemic Stroke, Transient Ischemic Attack
AcoArt VI / Vertebral Artery Ostium Stenosis in China
The purpose of this study is to determine whether DEB is not inferior to common bare metal stent using under in long-term vessel patency and inhibiting restenosis in Vertebral Artery Ostium Stenosis
- Trial name
- NCT03910166
- Testing
- drug-coated balloon catheter（Orchid, Acotec）, Intracranial artery stent system（APOLLO）
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Acotec Scientific Co., Ltd