Clinical trials: Transient Ischaemic Attack
Stroke, Transient Ischemic Attack
Tailored Intervention to Improve Patient Adherence to Secondary Stroke Prevention Medication
Patient suffering a Transient Ischemic Attack (TIA) or stroke are subsequently at high risk of a new stroke, however, poor adherence to secondary prevention medications occurs frequently within this patient group.
- Trial name
- NCT01684176
- Testing
- Complex tailored intervention, Usual care
- Where
- Denmark
- Volunteers
- 211 people
- Sponsor
- Odense University Hospital
Minor Stroke, Non-disabling Stroke
Stroke School -Including Physical Exercise, Patient Education and Individual Follow-up Sessions
In a randomized controlled trial the effect of 12 weeks of cross-sectorial physical exercise combined with patient education and individual follow-up session is investigated in patients with minor stroke or non-disabling stroke.
- Conditions
- Minor Stroke, Non-disabling Stroke, Transient Ischemic Attack
- Trial name
- NCT04945174
- Testing
- Cardiorespiratory exercise combined with patient education and individual follow-up sessions
- Where
- 2 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Herlev Hospital
Obstructive Sleep Apnea, Stroke
Diagnosis and Treatment of Sleep Apnea in Cerebrovascular Disease
Sleep apnea is common among Veterans with cerebrovascular disease (stroke or transient ischemic attack [TIA]), leads to hypertension, and is associated with recurrent stroke and death.
- Conditions
- Obstructive Sleep Apnea, Stroke, Transient Ischemic Attack, Hypertension
- Trial name
- Go To Sleep (NCT00984308)
- Testing
- CPAP Therapy for Newly Diagnosed Obstructive Sleep Apnea (OSA)
- Where
- 2 sites in United States
- Volunteers
- 225 people
- Sponsor
- VA Office of Research and Development
Acute Ischemic Stroke, Transient Ischemic Attack
The Extended CTA for the Successful Screening of Cardioaortic Thrombus in Acute Ischemic Stroke and TIA (DAYLIGHT) Trial
Embolic strokes of undetermined source (ESUS) represent a subset of cryptogenic strokes that are suspected to have an occult embolic source.
- Conditions
- Acute Ischemic Stroke, Transient Ischemic Attack, Intracardiac Thrombus
- Trial name
- DAYLIGHT (NCT05522244)
- Testing
- extended CTA
- Where
- Canada
- Volunteers
- 830 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Stroke, Transient Ischemic Attack
The PREVENTS Trial: The Preventing Recurrent Events in Veterans Navigating Transient Ischemic Attack (TIA) or Stroke Trial
National recommendations state that patients with a history of transient ischemic attack (TIA) or ischemic stroke should receive hypertension treatment, including antihypertensive medication and lifestyle modification, with a…
- Trial name
- PREVENTS (NCT01020851)
- Testing
- tailored intervention
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Narrows Institute for Biomedical Research
Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction
Clinical Impact of Using IMPROVE to Select Patients for Carotid Revascularisation
Narrowing of the carotid artery due to atherosclerosis with an unstable plaque can cause a stroke. Patients with carotid artery disease who have had a TIA or minor stroke and are at high risk of another stroke are often treated…
- Conditions
- Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction, Stroke Ischemic, Atheroscleroses
- Trial name
- IMPROVE (NCT07556887)
- Testing
- IMPROVE Risk Model
- Where
- 10 sites in Netherlands
- Volunteers
- 613 people
- Sponsor
- Maastricht University Medical Center
Transient Ischemic Attack, Stroke
Apixaban for Early Prevention of Recurrent Embolic Stroke and Hemorrhagic Transformation
The purpose of this study is to evaluate if Apixaban will decrease the complication of having another stroke for people who have atrial fibrillation if initiated earlier than standard of care.
- Conditions
- Transient Ischemic Attack, Stroke, Atrial Fibrillation
- Trial name
- AREST (NCT02283294)
- Testing
- Apixaban, Warfarin
- Where
- 5 sites in United States
- Volunteers
- 91 people
- Sponsor
- University of South Florida
Stroke Acute, Stroke (CVA) or Transient Ischemic Attack
Evaluating the Effect of Nurse-Led Stroke Transitional Care in Tanzania
The goal of this observational study is to assess the effects of nurse-led stroke transitional care in stroke survivors, caregivers and healthcare providers who participate in nurse-led stroke transitional care program to improve…
- Trial name
- NCT07319312
- Testing
- Nurse-led stroke transitional care program
- Where
- Tanzania
- Volunteers
- 130 people
- Sponsor
- Shandong University
Stroke, Cerebral Infarction
SouthErn China REgisTry for Stroke on Traditional Chinese Medicine
Stroke is the first most common cause of death in China and one of the major causes of functional disability in the adult population.The burden of stoke is significantly increased in China in recent years.
- Conditions
- Stroke, Cerebral Infarction, Transient Ischemic Attack, Cerebral Hemorrhage
- Trial name
- SECRETS-TCM (NCT03380481)
- Testing
- observational only-no intervention
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Yefeng Cai
Left Atrial Appendage Exclusion
AtriCure Exclusion of the LAA in Patients Undergoing Concomitant Cardiac Surgery
Prospective, non-randomized trial to evaluate the safety and efficacy of the LAA Exclusion Device (Clip) for the exclusion of the LAA via epicardial tissue approximation.
- Trial name
- EXCLUDE (NCT00779857)
- Testing
- AtriCure LAA Exclusion System
- Where
- 7 sites in United States
- Volunteers
- 70 people
- Sponsor
- AtriCure, Inc.
Haemorrhagic Stroke, Ischaemic Stroke
Digital Application for Stroke Health
Stroke is a leading cause of death and long-term disability worldwide. Despite substantial advances in acute stroke care, there remains a lack of evidence-based digital solutions to support patients after hospital discharge.
- Conditions
- Haemorrhagic Stroke, Ischaemic Stroke, Transient Ischemic Attack (TIA)
- Trial name
- DASH (NCT07511868)
- Testing
- StrokeApp, Standard care
- Where
- 7 sites in Austria
- Volunteers
- 500 people
- Sponsor
- VASCage GmbH
Acute Ischemic Stroke, Haemorrhagic Stroke
Translational Immunodiagnostics in Stroke (TrImS)
In adult patients presenting to emergency departments within 24 hours of symptom onset with suspected acute stroke, we aim: 1. to identify early brain- and pathology-specific circulating, whole blood, plasma and serum panorOmic…
- Conditions
- Acute Ischemic Stroke, Haemorrhagic Stroke, Transient Ischemic Attacks, Cardioembolic Stroke
- Trial name
- TrImS (NCT05300997)
- Testing
- Biomarker blood draw and saliva collection
- Where
- China
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Ischemic Stroke, Transient Ischemic Attack (TIA)
Ambulatory Stroke Unit Treatment for Elderly Patients
ARTIFICE is a prospective, multicenter, randomized, controlled, exploratory non-inferiority trial evaluating whether an ambulatory stroke unit model (aSU) is non-inferior to conventional inpatient stroke unit care (SU) in…
- Conditions
- Ischemic Stroke, Transient Ischemic Attack (TIA), Retinal Ischemia
- Trial name
- ARTIFICE (NCT07420374)
- Testing
- Ambulatory Stroke Unit Care, Conventional Stroke Unit Care
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- University Hospital Heidelberg
Hypertension, Stroke
Center for Stroke Disparities Solution - Community Transitions Intervention
The Stroke CTI study is a 3 arm randomized, controlled trial designed to assess the effectiveness of a nurse practitioner (NP) only and a NP and health coach (HC) community transitions intervention (CTI) in reducing secondary…
- Conditions
- Hypertension, Stroke, Transient Ischemic Attack
- Trial name
- CSDS (NCT01918891)
- Testing
- Nurse Practitioner Only, Nurse Practitioner + Health Coach
- Where
- United States
- Volunteers
- 495 people
- Sponsor
- Visiting Nurse Service of New York
Alzheimer's Disease, Small Vessel Disease White Matter Hyperintensities Subtype
Amyloid and Glucose PET Imaging in Alzheimer and Vascular Cognitive Impairment Patients With Significant White Matter Disease
The prevalence of both Alzheimer's Disease (AD) and stroke doubles each decade over 65 years old. Both are major causes of dementia, currently estimated to affect 46 million people worldwide.
- Conditions
- Alzheimer's Disease, Small Vessel Disease White Matter Hyperintensities Subtype, Vascular Cognitive Impairment
- Trial name
- MITNEC C6 (NCT02330510)
- Where
- 8 sites in Canada
- Volunteers
- 80 people
- Sponsor
- Dr. Sandra E Black
Stroke, Transient Ischemic Attack (TIA)
Pharmacogenomics in Stroke: Feasibility of CYP2C19 Testing
The purpose of this research study is to explore whether genetic testing can offer a personalized and timely approach to assist physicians in making more informed medication decisions for stroke or high-risk transient ischemic…
- Trial name
- CYP-FAST (NCT06943586)
- Testing
- CYP2C19 Genotype Guided DAPT (dual antiplatelet therapy)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Alabama at Birmingham
Transient Ischemic Attack
Korean Transient Ischemic Attack eXpression Registry
This study is to determine the clinical and neuroimaging characteristics of Transient Ischemic Attacks in Korean populations.
- Trial name
- KTX registry (NCT01870531)
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Seoul National University Boramae Hospital
Ischemic Stroke, TIA
Personalized Antiplatelet Secondary Stroke PRevenTion
This is a descriptive study designed to evaluate the safety and feasibility of a precision medicine approach to antiplatelet selection for secondary stroke prevention.
- Trial name
- PASSPoRT (NCT03979781)
- Testing
- tailored antiplatelet selection, standard of care
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- State University of New York - Upstate Medical University
Ischemic Stroke, Ischemia
Biomarkers of Acute Stroke in Clinic
The proposed study will investigate the clinical use of the ISCDX test that may differentiate between diverse stroke etiologies as listed below: Aim 1: Differentiate between cardioembolic and large artery atherosclerotic ischemic…
- Conditions
- Ischemic Stroke, Ischemia, Atrial Fibrillation, Transient Ischemic Attack
- Trial name
- BASIC (NCT03897478)
- Testing
- ISCDX blood test
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Ischemia Care LLC
Embolic Stroke of Undetermined Source, Transient Ischemic Attack
RoBotic TCD Ultrasound BubbLe Study Compared to Transthoracic Echocardiography for Detection of Right to Left Shunt
This study is a multi-center, prospective, single-arm, non-significant risk (NSR) device study in which up to 150 evaluable subjects with suspicion of embolic stroke of undetermined source (ESUS) will be evaluated with NB-IS TCD…
- Conditions
- Embolic Stroke of Undetermined Source, Transient Ischemic Attack, Right-To-Left Atrial Shunt, Patent Foramen Ovale
- Trial name
- BUBL (NCT04604015)
- Testing
- NeuralBot Investigational System, Transthoracic Echocardiography (TTE)
- Where
- 7 sites in United States
- Volunteers
- 154 people
- Sponsor
- NeuraSignal Inc dba NovaSignal