Clinical trials: Transient Tachypnea
Ultrasonic Diagnosis
Lung Ultrasound as a Predictor of Mechanical Ventilation in Neonates Older Than 32 Weeks
Neonatal respiratory distress prognosis may be difficult to estimate at admission. Lung ultrasound is a useful diagnostic tool that is quick, requires little training and is radiation free.
- Trial name
- NCT02449863
- Testing
- Lung ultrasound
- Where
- 2 sites in Spain
- Volunteers
- 105 people
- Sponsor
- Hospital Sant Joan de Deu
Transient Tachypnea of the Newborn, PPHN
Evaluation of the Prevalence of Persistent Pulmonary Hypertension in Neonates
Transient Tachypnea of the Newborn (TTN) is one of the common causes of neonatal respiratory distress as a result of delayed clearance of fetal lung fluid. Neonates with TTN usually require noninvasive respiratory support (e.g.
- Trial name
- PRE-HIFREQ (NCT03499418)
- Testing
- modified Silverman scale, echocardiography
- Where
- Poland
- Sponsor
- Princess Anna Mazowiecka Hospital, Warsaw, Poland
Wet Lung
Role of Cord Blood Hormones and Epinephrine in the Development of Transient Tachypnea of the Newborn
In this prospective, cross-sectional study, the aim was to investigate the possible role of cord stress hormones; adrenocorticotropic hormone (ACTH), cortisol, epinephrine, sT3, sT4, and thyroid-stimulating hormone (TSH) in the…
- Trial name
- NCT01149928
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara University
Transient Tachypnea of the Newborn
Physiologically Based Cord Clamping To Improve Neonatal Outcomes After Elective Cesarean Delivery
Before birth, the baby's lungs are filled with fluid and babies do not use the lungs to breathe, as the oxygen comes from the placenta. As delivery approaches, the lungs begin to absorb the fluid.
- Trial name
- PhyCord1 (NCT06278415)
- Testing
- Physiological based cord clamping, Differed cord clamping
- Where
- 2 sites in Belgium
- Volunteers
- 50 people
- Sponsor
- Queen Fabiola Children's University Hospital
Diastolic Dysfunction, Neonatal Encephalopathy
Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography
The goal of this single-centre longitudinal observational study is to create reference values for diastolic function parameters in neonates born at 35 weeks' gestation or above, and to assess the influence of pre-defined…
- Conditions
- Diastolic Dysfunction, Neonatal Encephalopathy, Small for Gestational Age at Delivery, Transient Tachypnea of the Newborn
- Trial name
- DiFuSE (NCT06200519)
- Where
- Ireland
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University College Cork
Newborn Rds, Transient Tachypnea of the Newborn
LUNG ULTRASONOGRAPHY DECREASES RADIATION EXPOSURE
We aimed to decrease in the number of chest X-rays in newborns with respiratory distress, with the use of lung ultrasonography. From January 2019 to June 2020, 104 newborn infants with respiratory distress enrolled in this study.
- Conditions
- Newborn Rds, Transient Tachypnea of the Newborn, Pneumonia
- Trial name
- LUDRE (NCT04722016)
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Hacettepe University
TTN, Respiratory Failure
the Inhaled β2-adrenergic Receptor Agonist for Transient Tachypnoea of the Newborn (the REFSAL Trial)
Clinical trial evaluating the efficacy and safety of salbutamol for the treatment of neonates with a gestational age between 32 and 42 weeks with transient tachypnoea of the newborn (TTN).
- Conditions
- TTN, Respiratory Failure, PPHN
- Trial name
- REFSAL (NCT05527704)
- Testing
- Salbutamol, 0,9% Chloride Sodium
- Where
- Poland
- Volunteers
- 608 people
- Sponsor
- Medical University of Warsaw
Respiratory Distress Syndrome, Newborn, Transient Tachypnea of the Newborn
Efficacy of Antenatal Steroids in Reducing Respiratory Morbidities in Late Preterm Infants
The hypothesis of the study is that administration of antenatal steroid to women at high risk of preterm birth after 34 weeks of gestation would reduce the risk of respiratory complications, specifically Respiratory Distress…
- Trial name
- NCT01206946
- Testing
- Betamethasone, Normal Saline
- Where
- 5 sites in Lebanon
- Volunteers
- 700 people
- Sponsor
- American University of Beirut Medical Center
TTN
The Effectiveness of Inhaled Salbutamol in the Management of Transient Tachypnea of the Newborn(TTN)
TTN is the most common respiratory disorder in the perinatal period, causing 40% of cases of respiratory distress after birth. Lung fluid absorption is initiated by beta-adrenergic agonists, such as endogenous steroids and…
- Trial name
- NCT07350421
- Testing
- Salbutamol (Albuterol), Normal Saline
- Where
- Syria
- Volunteers
- 1 people
- Sponsor
- Latakia University
Congenital Pneumonia, Transient Tachypnea of the Newborn
Comparison of Congenital Pneumonia and Transient Tachypnea of the Newborn
Accurate and timely differentiation between transient tachypnea of the newborn (TTN) and congenital pneumonia is essential in neonatal care, as it facilitates prompt initiation of appropriate treatment, reduces the risk of…
- Trial name
- NCT06803355
- Testing
- complete blood count, CRP, blood smear test, blood culture, chest X- ray
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Dr. Behcet Uz Children's Hospital
Respiratory Distress Syndrome, Newborn, Transient Tachypnea of the Newborn
The Role of Sustained Inflation on Short Term Respiratory Outcomes in Term Infants
Sustained inflation (SI) has been reported to be effective for reducing the need for intubation and/or invasive ventilation in preterm infants.
- Conditions
- Respiratory Distress Syndrome, Newborn, Transient Tachypnea of the Newborn, Respiratory Morbidity
- Trial name
- NCT03165305
- Testing
- Sustained Inflation
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Transient Tachypnea of the Newborn, Fluid Therapy
Restricted Fluid Therapy for Newborn Breathing Problems
Evidence suggests that increased intravascular and interstitial fluid load in neonates with transient tachypnea of the newborn (TTN) may delay the clearance of fetal alveolar fluid (FAF).
- Trial name
- NCT07549945
- Testing
- restricted fluid regimen, Standart fluid
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hitit University
Transient Tachypnea of the Newborn
High Flow Nasal Cannula Versus Bubble Nasal CPAP for the Treatment of Transient Tachypnea of the Newborn in Infants ≥ 35 Weeks Gestation
The primary objective is to determine whether High Flow Nasal Cannula (HFNC) is a superior respiratory modality for neonates ≥36 weeks with transient tachypnea of the newborn (TTN) when compared to the standard of care modality…
- Trial name
- NCT01270581
- Testing
- High Flow Nasal Cannula, Bubble Nasal CPAP
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Respiratory Distress Syndrome, Newborn, Respiratory Distress Syndrome in Premature Infant
Predicting the Need for Prolonged Respiratory Support in Neonates Delivered in a Lower-Level NICU Setting
The purpose of this study is to analyze the gastric fluid aspirated from the stomachs of neonates receiving routine post-delivery care to predict the need for prolonged respiratory support (>6 hours of life).
- Conditions
- Respiratory Distress Syndrome, Newborn, Respiratory Distress Syndrome in Premature Infant, Transient Tachypnea of the Newborn, Meconium Aspiration Syndrome
- Trial name
- NCT07344714
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Transient Tachypnea of the Newborn
Reducing Respiratory Distress After Elective Caesarean Birth Through Knee-chest-flexion: a Randomized Controlled Trial
Planned caesarean birth is a risk factor for the development of neonatal respiratory distress commonly known as transient tachypnoea of the newborn.
- Trial name
- NCT06270823
- Testing
- Knee-to-chest-flexion manoeuvre
- Where
- Tanzania
- Volunteers
- 562 people
- Sponsor
- Kilimanjaro Clinical Research Institute
Transient Tachypnea of the Newborn
PATET Ratio to Rule Out Transient Tachypnea of the Newborn
This study aims to find out whether diagnosis of Transient Tachypnea of the Newborn(TTN) can be predicted via evaluating pulmonary artery Doppler indices.
- Trial name
- PATET (NCT02965365)
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Kayseri Education and Research Hospital
Maternal Attachment, Breastfeeding
Reciprocal Mother-Infant Voice Exposure in the Neonatal Intensive Care Unit
This randomized controlled trial evaluates the effect of reciprocal maternal-infant voice exposure on maternal attachment and breastfeeding outcomes in a neonatal intensive care unit (NICU).
- Conditions
- Maternal Attachment, Breastfeeding, Transient Tachypnea of the Newborn, Neonatal Intensive Care Unit
- Trial name
- NCT07597954
- Testing
- Reciprocal Voice Exposure Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Biruni University
TTN
Role of Salbutamol in the Management of Transient Tachypnea of the New Born
Role of Salbutamol in the management of transient tachypnea of the new born
- Trial name
- NCT06921291
- Testing
- Salbutamol (Ventolin®)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Khyber Teaching Hospital
Transient Tachypnoea of the Newborn
Trial on Treatment With Inhaled Furosemide of Preterm and Term Neonates With Transient Tachypnoea
In this study we will prospectively analyze the benefit of inhaled furosemide for preterm and term neonates with Transient Tachypnoea.
- Trial name
- NCT01407848
- Testing
- Furosemide, Saline 0,9%
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Cologne
Respiratory Distress, Transient Tachypnea of the Newborn
Effect of Supine or Prone Position After Caesarean Birth
Respiratory Distress is a frequent clinical diagnosis of babies delivered by elective Caesarean birth. There has been no study comparing the efficacy of immediately positioning a newly born infant prone vs.
- Conditions
- Respiratory Distress, Transient Tachypnea of the Newborn, Delayed Transition of the Newborn, Persistent Pulmonary Hypertension
- Trial name
- NCT01310153
- Testing
- prone positioning, Supine
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center