Clinical trials: Transition
Opioid Withdrawal
Combining Pregabalin (LYRICA®) With Lofexidine (LUCEMYRATM) to Treat OPIOID Withdrawal
A phase II double-blind placebo-controlled parallel group clinical trial that will randomize 90 subjects to investigate whether pregabalin (PGB) combined with Lofexidine (LFX) can reduce opioid withdrawal-related subjective…
- Trial name
- PGB-LOF (NCT04218240)
- Testing
- Pregabalin 200 MG capsules, Lofexidine 0.18Mg Tab
- Where
- 3 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Pennsylvania
Ischemic Stroke, Hemorrhagic Stroke
A Novel Transition Program to Reduce Disability After Stroke
This study evaluates a program designed to help individuals transition home from inpatient rehabilitation following an ischemic or hemorrhagic stroke.
- Trial name
- COMPASS (NCT03485820)
- Testing
- COMPASS, Stroke education
- Where
- United States
- Volunteers
- 185 people
- Sponsor
- Washington University School of Medicine
Rheumatoid Arthritis
A Phase III Transition Study of DRL Rituximab to Reference Medicinal Products
The objective of the current study is to assess the immunogenicity and safety of transitioning subjects with RA to DRL_RI from US-rituximab/EU-rituximab to continued treatment with US-rituximab/EU-rituximab.
- Trial name
- RI-01-007 (NCT04268771)
- Testing
- Experimental: Arm A: DRL_RI, Arm B: Rituxan®/Mabthera®
- Where
- 26 sites in United States
- Volunteers
- 140 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Presbyopia
Multifocal Visual Performance Study
The purpose of this trial was to compare the functional visual performance of Precision Profile Multifocal (MF) contact lenses to Progressive Addition Lens (PAL) spectacles in a presbyopic population.
- Trial name
- NCT03757039
- Testing
- Multifocal soft contact lenses, Progressive addition lens spectacles
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 42 people
- Sponsor
- Alcon Research
Perimenopausal Disorder, Stress, Emotional
The Menopause Transition: Estrogen Variability, Stress Reactivity and Mood
Women in the menopause transition ('perimenopause') are exposed to extreme hormone variability, tend to experience a unique set of severe stressors (e.g., divorce, death of loved ones), and are also at substantially elevated risk…
- Trial name
- Changes (NCT03003949)
- Testing
- Estradiol Patch, 0.1 Mg/24 Hours Weekly Transdermal Film, Extended Release, Progesterone Capsule
- Where
- 2 sites in United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Professional Fulfillment, Professional Identity Formation
A Professional Development Programme (ProDeveloP) for Newly Graduated Nurses
This clinical study aims to implement and evaluate a professional development programme (ProDeveloP) designed to facilitate the transition of newly graduated nurses (NGNs) into their new roles.
- Conditions
- Professional Fulfillment, Professional Identity Formation, Professional Quality of Life, Support Program
- Trial name
- NCT06742047
- Testing
- Professional development programme
- Where
- Sweden
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Mälardalen University
Mental Health Issue
An Evaluation of Virtual Psychiatric Transition of Care Offered in Behavioral Health
The primary objective is to evaluate the effectiveness of a post inpatient discharge virtual psychiatric care team compared to standard care, to reduce 30-day all cause non-elective acute care utilization (Emergency Department…
- Trial name
- VPTC (NCT05460078)
- Testing
- Virtual Psychiatric Transition of Care Program
- Where
- 7 sites in United States
- Volunteers
- 7,526 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
College Student Drinking
Adaptive Preventive Intervention for College Alcohol Use
This research project is designed to promote health among first-year college students by implementing an adaptive sequence of preventive intervention strategies to motivate heavy-drinking college students to access existing…
- Trial name
- NCT03930524
- Testing
- Personalized Normative Feedback (PNF), Self-Monitoring (SM), Web-BASICS
- Where
- United States
- Volunteers
- 891 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Childhood-onset Growth Hormone Deficiency, Pituitary Dwarfism
Cool.Click™ Adolescent Transition Study: Study of Saizen® in Subjects With Childhood-onset Growth Hormone Deficiency
The primary objective is to evaluate the efficacy and safety of two different dose regimens of r-hGH (Saizen®) in subjects with childhood-onset growth hormone deficiency (COGHD) during the transition phase from childhood to…
- Trial name
- NCT00109733
- Testing
- recombinant human growth hormone
- Where
- 9 sites in United States
- Volunteers
- 31 people
- Sponsor
- EMD Serono
Sickle Cell Disease
Music Therapy in Sickle Cell Transition Study
The purpose of this study is to investigate the effects of the BEATS Music Therapy Program on the self-efficacy, trust, knowledge, and adherence of young adult patients with sickle cell disease during transition.
- Trial name
- NCT02466555
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University Hospitals Cleveland Medical Center
Menopause
Assessment of the Transfer of Using Levonorgestrel Intrauterine System (LNG IUS) as a Contraceptive to Using it as Part of Hormone Replacement Therapy (HRT).
The study has been designed to look at the transfer from using LNG IUS for contraception only, in reproductive age to using it for endometrial protection in menopausal age.
- Trial name
- NCT00185458
- Testing
- LNG IUS
- Where
- 12 sites in Belgium, Finland and 2 more
- Volunteers
- 394 people
- Sponsor
- Bayer
Solid Tumors, Lymphoma
Indenoisoquinoline LMP744 in Adults With Relapsed Solid Tumors and Lymphomas
Background: The new drug LMP744 (NSC 706744) damages deoxyribonucleic acid (DNA). This causes cell death. Researchers want to see if it can treat certain kinds of cancer.
- Trial name
- NCT03030417
- Testing
- LMP744, Ondansetron, Olanzapine
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- National Cancer Institute (NCI)
Acute Instabilities Thoracic, Lumbar and Sacral Spine, Chronic Instabilities Thoracic, Lumbar and Sacral Spine
A Prospective Randomized Postmarket Clinical Study of the TRANSITION Stabilization System
This postmarket surveillance study is being conducted to evaluate the TRANSITION Stabilization System as an adjunct to fusion in the treatment of acute or chronic instabilities or deformities of the thoracic, lumbar and sacral…
- Conditions
- Acute Instabilities Thoracic, Lumbar and Sacral Spine, Chronic Instabilities Thoracic, Lumbar and Sacral Spine, Deformities of the Thoracic, Lumbar and Sacral Spine
- Trial name
- NCT02184520
- Testing
- TRANSITION, REVERE
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Globus Medical Inc
Cardiac Condition
Transition From Hospital to Home Post Cardiac Condition
The study had three parts: Part 1: Patients (or their home caretakers) who live outside of Denver and receive their primary care at a location other than the Denver VAMC were interviewed after their discharge.
- Trial name
- NCT01431846
- Testing
- Intervention
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
HIV-1-infection, Adolescent Behavior
InTSHA: Interactive Transition Support for HIV-infected Adolescents Using Social Media
The goal of this study is to develop and evaluate a social media behavioral intervention based on the Social-ecological Model of Adolescent and Young Adult Readiness to Transition (SMART) to improve transition care for…
- Trial name
- InTSHA (NCT03624413)
- Testing
- Social Media Intervention, Standard of Care
- Where
- South Africa
- Volunteers
- 80 people
- Sponsor
- Emory University
Menopause
Electro-acupuncture for Menopausal Transition Symptoms
This trial aimed at exploring the efficacy as well as safety of electro-acupuncture for MT symptoms.
- Trial name
- NCT02471755
- Testing
- Eelectro-acupuncture
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Pulmonary Arterial Hypertension
Safety Evaluation of Inhaled Treprostinil Administration Following Transition From Inhaled Ventavis in Pulmonary Arterial Hypertension (PAH) Subjects
This is a 24-month, multi-center, prospective, open-label, safety evaluation in PAH subjects following transition from a stable dose of inhaled iloprost (Ventavis).
- Trial name
- NCT00741819
- Testing
- Inhaled treprostinil
- Where
- 15 sites in United States
- Volunteers
- 73 people
- Sponsor
- United Therapeutics
Chronic Insomnia
Safety and Efficacy of Chronic Hypnotic Use 2
This proposal will assess risks for transition from therapeutic hypnotic use to abuse in people with insomnia. The investigators will study a hypothesized at-risk sub-population, insomniacs with hyperarousal, and compare two…
- Trial name
- CIS2 (NCT02456532)
- Testing
- Zolpidem CR, Eszopiclone
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Autism Spectrum Disorder, Family Relations
Development of a Family-Based Transition Planning Program for Culturally-Diverse Youth on the Autism Spectrum
The goal of this clinical study is to develop a community-based program to support family members of transition-aged youth on the autism spectrum to help them plan for the future. The main aims of the study are: 1.
- Trial name
- NCT05965648
- Testing
- Families FORWARD (Focusing on Relationships, Well-being, and Responsibility aheaD)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
CHF, COPD
A Technology Assisted Care Transition Intervention for Veterans With CHF or COPD
Transition from hospital to home places patients in jeopardy of adverse events and increases their risk for rehospitalization. CHF is the most prevalent chronic condition among U.S.
- Trial name
- TACT (NCT02632552)
- Testing
- Technology-assisted care transition intervention, Active attention control
- Where
- 5 sites in United States
- Volunteers
- 140 people
- Sponsor
- VA Office of Research and Development