Clinical trials: Transition
Autism Spectrum Disorder (ASD), Motivation
Motivation for Daily Living Skills
The goal of this clinical trial is to enhance motivation to complete daily living skills among 16 to 25-year-old autistic teens and young adults.
- Trial name
- NCT07159308
- Testing
- Intrinsic Motivation Treatment, Extrinsic Motivation Treatment, Combined Intrinsic and Extrinsic Motivation Treatment
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Children's Hospital of Philadelphia
Metabolic Diseases, Cancer
Transitional Growth Hormone (GH) Use in Growth Hormone Deficient (GHD) Cancer Survivors
Cure rates for childhood malignancies have improved at a remarkable pace.With the increasing cure rate came recognition of the long-term detrimental effects of radiotherapy and chemotherapy, known as "late-effects".
- Trial name
- NCT02629926
- Testing
- GH Replacement (NutropinAq®), No additional treatment
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Diabetes Mellitus, Type 2
A "Real World" Trial to Determine Efficacy and Health Outcomes of Toujeo Compared to "Standard of Care" Basal Insulin in Patients Already Using Basal Insulin
Primary Objective: To demonstrate noninferiority of Toujeo versus "standard of care" basal insulin therapy as measured by glycated hemoglobin (HbA1c) change Secondary Objectives: To demonstrate superiority of Toujeo versus…
- Trial name
- REGAIN CONTROL (NCT02967211)
- Testing
- insulin glargine (U300), insulin glargine (U100), NPH insulin
- Where
- 118 sites in Brazil, Finland and 8 more
- Volunteers
- 609 people
- Sponsor
- Sanofi
Autism or Autistic Traits, Family Relations
Transitioning Together Boston
A randomized controlled trial will be conducted to determine the effects of an adapted family-centered autism transition intervention called Transitioning Together/Juntos en la Transición on meaningful outcomes for families.
- Trial name
- NCT05599711
- Testing
- Transitioning Together (TT) / Juntos en la Transicion (JET), Usual autism transition care
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Boston Medical Center
Hemophilia A Patient
Real-World Joint Outcomes After Selective Transition to Low-Dose Emicizumab in Pediatric Hemophilia A
Recent studies have shown that pharmacokinetic (PK)-guided extended half-life (EHL) factor VIII can improve joint health in patients with hemophilia A.
- Trial name
- NCT07439055
- Testing
- Switching to low dose emicizumab
- Where
- Thailand
- Volunteers
- 18 people
- Sponsor
- Chulalongkorn University
Diabetes Mellitus, Type 2 Treated With Insulin
Risk of Hypoglycemia in the Transition From Inpatient to Outpatient Setting. Comparative Study of Basal-bolus Insulin Versus Basal Insulin Plus GLP-1 Analogue
The association of insulin degludec with liraglutide in the same device (IDegLira) is a potent but at the same time safe drug that reduces the risk of hypoglycemia when compared to a basal or basal-bolus insulin schedule.
- Trial name
- NCT05767255
- Testing
- insulin degludec + liraglutide, Insulin Glargine - Insulin Aspart
- Where
- Colombia
- Volunteers
- 66 people
- Sponsor
- Hospital Universitario San Ignacio
Solid Tumor, MET Alteration
FIH Trial of VERT-002 in Patients With Locally Advanced or Metastatic Solid Tumors With MET Alterations
The goal of this clinical trial is to investigate the safety, the activity of VERT-002 (PFL-002), and the optimal safe dose to be used, in participants with solid tumors including non-small cell lung cancer.
- Trial name
- NCT06669117
- Testing
- VERT-002
- Where
- 19 sites in United States, Belgium and 7 more
- Volunteers
- 140 people
- Sponsor
- Pierre Fabre Medicament
Traumatic Brain Injury
Brain Injury Rehabilitation Improving the Transition Experience
Each year, about 2.8 million people sustain a traumatic brain injury (TBI) in the United States, and at least 25 percent of these injuries are classified as moderate to severe.
- Trial name
- BRITE (NCT03422276)
- Testing
- Rehabilitation Discharge Plan, Rehabilitation Transition Plan
- Where
- 6 sites in United States
- Volunteers
- 1,555 people
- Sponsor
- University of Washington
Stroke
The Missing Link- Development and Feasibility Evaluation of Person-centred Transitions From the Stroke Unit to the Home
The aim is to design, implement and evaluate new person-centred transitions between stroke units and the home. The development of person-centred transition will be performed together by people with stroke, significant others…
- Trial name
- Missing Link (NCT02925871)
- Testing
- Co-designed person-centred care transitions, Current care transitions
- Where
- 2 sites in Sweden
- Volunteers
- 49 people
- Sponsor
- Karolinska Institutet
Well-being
Develop and Validation of Measurement-Based Transition Assistance
Although some Veterans seek help when they experience post-military readjustment challenges, many do not. One factor that stands in the way of Veterans' willingness to seek help for these challenges is their lack of knowledge…
- Trial name
- MBTA (NCT05384171)
- Testing
- Measurement-Based Transition Assistance (MBTA)
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- VA Office of Research and Development
Mechanical Ventilation Complication, Caffeine
The Caffeine Therapy in the Fetal to Neonatal Transition
Introduction: The caffeine is used in the treatment for apnea of prematurity and it has several positive effects in the neurodevelopment of preterm babies.
- Conditions
- Mechanical Ventilation Complication, Caffeine, Ventilator Lung; Newborn
- Trial name
- NCT05454332
- Testing
- Early Caffeine administration, Control Group
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pregnancy
Supporting Couples' Perinatal Sexual Well-being: Testing the Introductory Modules of a Novel Prevention Program (STORK)
Most new parents will experience changes to their sexual relationship during the perinatal period, yet no accessible prevention programs exist to support couples in navigating these changes.
- Trial name
- NCT07036484
- Testing
- Online program
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Dalhousie University
Type 1 Diabetes
Transition Preparation Intervention for Young Adults With Type 1 Diabetes
The purpose of this research study is to find out more about how to support young adults (ages 18-22) with type 1 diabetes as they prepare to transition from pediatric and adult endocrinology medical care.
- Trial name
- NCT03998475
- Testing
- Transition preparation intervention
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Virginia Commonwealth University
Obesity, Class III, Sleep Apnea, Obstructive
High-Intensity Progressive Inspiratory Muscle Training in Class III Obesity and Obstructive Sleep Apnea
The purpose of this study is to evaluate the feasibility and effects of a 12-week high-intensity progressive Inspiratory Muscle Training (IMT) program in individuals with Class III obesity (BMI ≥ 40 kg/m²) and obstructive sleep…
- Conditions
- Obesity, Class III, Sleep Apnea, Obstructive, Inspiratory Muscle Training
- Trial name
- NCT07469280
- Testing
- High-Intensity Progressive Inspiratory Muscle Training (IMT)
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of the State of Santa Catarina
Heart Failure With Preserved Ejection Fraction
Transitions of Care Clinic (TOCC)
The transition period from hospital to home is a time of heightened risk for patients to experience adverse events, medication errors, and readmission to the hospital.
- Trial name
- NCT06937827
- Testing
- HF Kit and Follow-ups
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Hackensack Meridian Health
Breastfeeding
Effects of Oral Stimulation and Supplemental Nursing System
This study aimed to investigate the effect of oral stimulation and a supplemental nursing system on the time to full maternal breastfeeding and sucking success in preterm infants.
- Trial name
- NCT05087043
- Testing
- Oral motor stimulation (OMS) and The supplemental nursing system (SNS)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Muğla Sıtkı Koçman University
Haemophilia
Determinants and Consequences of the Transition to Adulthood Among Adolescents With Haemophilia
Severe haemophilia is a rare disease characterized by spontaneous bleedings from early childhood, which may lead to various complications especially in joints.
- Trial name
- TRANSHEMO (NCT02866526)
- Testing
- Patient questionnaire
- Where
- 29 sites in France
- Volunteers
- 277 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Transitional Care, Mental Disorder in Adolescence
Psychiatry of Transition in a World in Transition
This clinical study evaluates risk and protective factor to develop psychopathology in transitional age youth. 300 patients will be recruited at the age of 17 years old and assessed at baseline and 2 years later.
- Conditions
- Transitional Care, Mental Disorder in Adolescence, Mental Health
- Trial name
- Transition_psy (NCT04333797)
- Testing
- Risk and Protective Factors Assessment
- Where
- 4 sites in Belgium
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Queen Fabiola Children's University Hospital
Colorectal Cancer
"High Levels of EMT-TFs for the Diagnosis of Colorectal Cancer (CRC)"
The present study is aimed at detecting and measuring mRNA levels of genes involved in epithelial to mesenchymal transition (EMT) in biological samples, i.e.
- Trial name
- NCT04323813
- Testing
- Liquid biopsy
- Where
- Italy
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Acute Kidney Injury
Transition of Acute Kidney Injury to Chronic Kidney Disease
Acute kidney injury is a complex clinical syndrome,associated with high short and long- term morbidity and mortality in critical ill patients.Acute kidney injury outcomes may vary from a complete resolution to a partial or…
- Trial name
- NCT04101110
- Testing
- Renal biopsy
- Where
- Egypt
- Volunteers
- 252 people
- Sponsor
- Assiut University