Clinical trials: Transitional Care
Pathologic Processes
Adapting Connect-Home Transitional Care for the Unique Needs of Persons With Alzheimer's Disease and Other Dementias and Their Caregivers
This primary purpose of this study will be to (1) examine the feasibility and acceptability of transitional care focusing on care needs of skilled nursing facility (SNF) patients with dementia and their caregivers (primary aim).
- Trial name
- NCT05887388
- Testing
- Connect-Home Plus
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of North Carolina, Chapel Hill
Heart Failure, Heart Failure Hospitalization
Teach-Back Discharge Education to Improve Self-Care and Reduce 30-Day Readmissions in Heart Failure Patients
This study aimed to improve how patients with heart failure understand and manage their condition after leaving the hospital. Many heart failure patients are readmitted within 30 days due to confusion about their discharge…
- Conditions
- Heart Failure, Heart Failure Hospitalization, Readmission, Hospital
- Trial name
- NCT07280208
- Testing
- Teach-Back Discharge Education
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Nova Southeastern University
Chronic Disease
Home Based Care Transitions Tailored by Cognition and Patient Activation
There is overwhelming evidence that patients with multiple chronic illnesses need better self-management skills. Discharge from the hospital may not be the most opportune time to be teaching patients these self-management skills.
- Trial name
- NCT02045147
- Testing
- Grp 1a Low Cognition, Low Activation Intervention, Grp 2a Low Cognition, High Activation Intervention, Grp 3a Normal Cognition, Low Activation Intervention
- Where
- United States
- Volunteers
- 263 people
- Sponsor
- University of Nebraska
Fallopian Tube Mucinous Adenocarcinoma, Ovarian Seromucinous Carcinoma
Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents
This phase II trial studies the possible benefits of treatment with different combinations of the drugs durvalumab, olaparib and cediranib vs.
- Conditions
- Fallopian Tube Mucinous Adenocarcinoma, Ovarian Seromucinous Carcinoma, Platinum-Refractory Fallopian Tube Carcinoma, Platinum-Refractory Ovarian Carcinoma
- Trial name
- NCT04739800
- Testing
- Biospecimen Collection, Cediranib Maleate, Computed Tomography
- Where
- 391 sites in United States, Puerto Rico
- Volunteers
- 120 people
- Sponsor
- National Cancer Institute (NCI)
Urothelial Cancer
A Study Of Avelumab In Patients With Locally Advanced Or Metastatic Urothelial Cancer (JAVELIN Bladder 100)
The main purpose of this study is to compare maintenance treatment with avelumab plus best supportive care (BSC) with BSC alone, to determine if avelumab has an effect on survival in patients with locally advanced or metastatic…
- Trial name
- NCT02603432
- Testing
- Avelumab, Best Supportive Care, Following the planned interim analysis for this study: Avelumab
- Where
- 382 sites in United States, Argentina and 27 more
- Volunteers
- 700 people
- Sponsor
- Pfizer
Coronary Artery Disease, Coronary Artery Bypass Graft Surgery
Transitional Rehabilitation in CABG Patients
The goal of this research study is to understand whether an at-home exercise program started soon after CABG surgery, and continuing for 4 weeks following discharge from the hospital, can preserve or improve physical function.
- Trial name
- NCT03892460
- Testing
- neuromuscular electrical stimulation
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Vermont
Palliative Care
Technology-enhanced Transitional Palliative Care for Family Caregivers
The purpose of this study is to evaluate the effect and cost of technology-enhanced transitional palliative care on family caregivers who provide care to a loved one after a hospitalization.
- Trial name
- NCT03339271
- Testing
- Technology-Enhanced Support, Usual Care Support
- Where
- United States
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Stroke, Transient Ischemic Attack
Comprehensive Post-Acute Stroke Services
The purpose of this pragmatic study is to investigate whether implementation of a comprehensive post-acute stroke service model that integrates Early Supported Discharge (ESD) and Transitional Care Management (TCM) for stroke…
- Trial name
- COMPASS (NCT02588664)
- Testing
- COMPASS Intervention
- Where
- 40 sites in United States
- Volunteers
- 6,024 people
- Sponsor
- Wake Forest University Health Sciences
Sepsis
Implementation and Effectiveness of Engagement and Collaborative Management to Proactively Advance Sepsis Survivorship
The purpose of this study is to evaluate if implementation of the Sepsis Transition and Recovery (STAR) program within a large healthcare system will improve outcomes for high-risk patients with suspected sepsis, while…
- Trial name
- ENCOMPASS (NCT04495946)
- Testing
- Sepsis Transition and Recovery (STAR) program, Usual care
- Where
- United States
- Volunteers
- 3,894 people
- Sponsor
- Wake Forest University Health Sciences
Early-stage Breast Cancer, Breast Cancer Female
The ConnectedCancerCare Pilot Study (CCC)
This study is an NCI-funded, randomized control pilot trial to evaluate: (1) the feasibility and acceptability of a web-based, personalized navigation tool (ConnectedCancerCare) and (2) explore whether the tool improves delivery…
- Conditions
- Early-stage Breast Cancer, Breast Cancer Female, Survivorship, Cancer Survivors
- Trial name
- CCC (NCT03618017)
- Testing
- CCC website, Static care plan
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Michigan Rogel Cancer Center
HIV, Hepatitis C
Criminal Justice Coordinated Transitional Care
This project aims to enroll 220 incarcerated individuals living with HIV, Hepatitis C (HCV), or history of substance misuse preparing for release into a pilot implementation study to test the feasibility and acceptability of an…
- Conditions
- HIV, Hepatitis C, Substance Use Disorders
- Trial name
- CJC-TraC (NCT05376371)
- Testing
- CJC-TraC
- Where
- 2 sites in United States
- Volunteers
- 219 people
- Sponsor
- University of Wisconsin, Madison
Standard Treatment Versus Engagement Focused Treatment
Improving Transitional Care Experiences in Mental Health
The cost of serious mental illness (SMI) in the U.S. is $317 billion annually. This translates to more than $1000 for every man, women, and child in the U.S. Hospitalization and Emergency Room (ER) visits have the highest costs.
- Trial name
- NCT02213198
- Testing
- Engagement focused care, Standard Care
- Where
- United States
- Volunteers
- 465 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Transitional Care, Caregivers
Connect-Home Clinical Trial
This study will test whether transitional care targeting care needs of seriously ill, skilled nursing facility (SNF) patients and their caregivers will help to improve SNF patient outcomes (preparedness for discharge, quality of…
- Conditions
- Transitional Care, Caregivers, Patient Discharge, Aging
- Trial name
- NCT03810534
- Testing
- Connect-Home
- Where
- United States
- Volunteers
- 654 people
- Sponsor
- University of North Carolina, Chapel Hill
Brain Injuries, Traumatic, Transitional Care
Enhancing the Transition From Hospital to Home for Patients With Traumatic Brain Injury and Families
Despite high risks of readmission and complex medical needs, there are no transitional care standards in the U.S. for patients with moderate-to-severe traumatic brain injury (TBI) discharged home from acute hospital care without…
- Conditions
- Brain Injuries, Traumatic, Transitional Care, Family Members, Patients
- Trial name
- R03 (NCT04584554)
- Testing
- BETTER Transitional Care Intervention
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Duke University
Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma
Testing the Combination of Cediranib and Olaparib in Comparison to Each Drug Alone or Other Chemotherapy in Recurrent Platinum-Resistant Ovarian Cancer
This randomized phase II/III trial studies how well cediranib maleate and olaparib work when given together or separately, and compares them to standard chemotherapy in treating patients with ovarian, fallopian tube, or primary…
- Conditions
- Fallopian Tube Clear Cell Adenocarcinoma, Fallopian Tube Endometrioid Adenocarcinoma, Fallopian Tube Serous Adenocarcinoma, Fallopian Tube Transitional Cell Carcinoma
- Trial name
- NCT02502266
- Testing
- Cediranib, Cediranib Maleate, Computed Tomography
- Where
- 398 sites in United States, Canada and 3 more
- Volunteers
- 582 people
- Sponsor
- National Cancer Institute (NCI)
HIV-1-infection, Adolescent Behavior
InTSHA: Interactive Transition Support for HIV-infected Adolescents Using Social Media
The goal of this study is to develop and evaluate a social media behavioral intervention based on the Social-ecological Model of Adolescent and Young Adult Readiness to Transition (SMART) to improve transition care for…
- Trial name
- InTSHA (NCT03624413)
- Testing
- Social Media Intervention, Standard of Care
- Where
- South Africa
- Volunteers
- 80 people
- Sponsor
- Emory University
Metastatic Urothelial Carcinoma, Unresectable Urothelial Carcinoma
Pemigatinib + Pembrolizumab vs Pemigatinib Alone vs Standard of Care for Urothelial Carcinoma (FIGHT-205)
The purpose of this study is to evaluate the safety and efficacy of pemigatinib plus pembrolizumab or pemigatinib alone versus the standard of care for participants with metastatic or unresectable urothelial carcinoma who are not…
- Trial name
- NCT04003610
- Testing
- Pemigatinib, Pembrolizumab, Gemcitabine
- Where
- 79 sites in United States, Austria and 14 more
- Volunteers
- 7 people
- Sponsor
- Incyte Corporation
Mental Disorder, Substance Use Disorders
Supported Employment in Patient Aligned Care Teams
In response to the Rehabilitation Research and Development (RR\&D) Deployment Health Research, this study addresses the delivery of an evidenced-based vocational rehabilitation, specifically Individual Placement and Support…
- Conditions
- Mental Disorder, Substance Use Disorders, Posttraumatic Stress Disorder, Major Depressive Disorder
- Trial name
- NCT02400736
- Testing
- Individual Placement and Support (IPS), Treatment as Usual Vocational Rehabilitation/Transitional Work (TUA-VR)
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- VA Office of Research and Development
Nonadherence, Patient, Polypharmacy
Pharmacist Intervention to Reduce Post-Hospitalization Utilization
This is a randomized trial testing a peri- and post-discharge pharmacist-led medication management intervention on post-discharge utilization, including both readmissions and emergency department visits within 30 days of…
- Conditions
- Nonadherence, Patient, Polypharmacy, Readmission
- Trial name
- NCT04071951
- Testing
- Pharmacist-led Hospital Discharge Care Intervention
- Where
- 2 sites in United States
- Volunteers
- 6,478 people
- Sponsor
- Cedars-Sinai Medical Center
Type 2 Diabetes Mellitus, Cardiometabolic Conditions
Mi Puente: My Bridge to Better Cardiometabolic Health and Well-Being
Mi Puente (or "My Bridge") is a culturally-tailored, interdisciplinary approach designed to support at-risk Hispanic patients and their caregivers pre- and post-hospital discharge as they navigate the multi-level barriers that…
- Conditions
- Type 2 Diabetes Mellitus, Cardiometabolic Conditions, Behavioral Health Concerns
- Trial name
- Mi Puente (NCT02723019)
- Testing
- Volunteer Peer Mentor+Behavioral Health Nurse
- Where
- United States
- Volunteers
- 536 people
- Sponsor
- Scripps Whittier Diabetes Institute