Clinical trials: Transmission, Other/Miscellaneous
Herpes Simplex, HIV Infections
An Open, Multicenter Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other Immunodeficiencies
To evaluate the safety and efficacy of intermittent intravenous (IV) foscarnet in the treatment of acyclovir-resistant herpes simplex virus (HSV) infections in AIDS patients and other immunocompromised patients.
- Trial name
- NCT00002272
- Testing
- Foscarnet sodium
- Where
- United States
- Sponsor
- Astra USA
Sexually Transmitted Infections, Gay
HIV/STD Risk and PrEP Implementation Messaging Among Gay, Bisexual, and Other Men Who Have Sex With Men
The goal of this observational study is to learn about awareness around PrEP use and adherence, condom use, sexual risk-taking behavior, and substance-using behaviors in men having sex with men.
- Conditions
- Sexually Transmitted Infections, Gay, Pre Exposure Prophylaxis
- Trial name
- MIC-DROP (NCT06183502)
- Testing
- Quantitative survey, HIV and STI testing, Qualitative Assessment
- Where
- 3 sites in United States
- Volunteers
- 675 people, healthy volunteers welcome
- Sponsor
- Emory University
Human Immunodeficiency Virus
Medical Mistrust Among Hispanic/Latino Gay, Bisexual and Other Men Who Have Sex With Men (HLMSM)
There is an urgent need to address HIV inequities and disparities in the US, particularly within vulnerable communities such as Hispanic/Latino gay, bisexual, and other men who have sex with men (HLMSM).
- Trial name
- NCT06132672
- Testing
- Navigators (peer navigator) training, delayed-intervention
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Hiv
Clinical Outcomes in HIV With Comorbidities
Multi-arm, non-randomized, quality of life
- Trial name
- NCT05824130
- Where
- Hong Kong
- Volunteers
- 300 people
- Sponsor
- Grace Lui
Cryptosporidiosis, HIV Infections
Azithromycin in the Treatment of Cryptosporidiosis in Patients Who Have Not Had Success With Other Drugs
To provide azithromycin for the treatment of individual patients with proven cryptosporidiosis whose disease has persisted or progressed despite prior therapies.
- Trial name
- NCT00002328
- Testing
- Azithromycin
- Where
- United States
- Sponsor
- Pfizer
Safer Sex
A Group-level Intervention to Reduce HIV/STI Risk for Women Who Have Sex With Women in Calgary and Toronto
The limited research that exists suggests that lesbian, bisexual and queer (LBQ) women are at similar risk for sexually transmitted infections (STI) as heterosexual women.
- Trial name
- NCT02067845
- Testing
- Adapted Many Men, Many Voices (3MV) group level intervention, A group-based HIV/STI prevention intervention for women who have sex with women
- Where
- 2 sites in Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Human Papillomavirus Infection
Throat and Other HPV-Related Cancers in Men: Identifying Them Early
This trial studies the screening of human papillomavirus (HPV)-related oropharyngeal and anogenital cancers. Learning the relationship between HPV and cancer risk in men who test positive for HPV antibodies or circulating HPV DNA…
- Trial name
- TRINITY (NCT02897427)
- Testing
- Biomarker Analysis, Biospecimen Collection, Ultrasonography
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
HIV Infections
Safety of EVG+RTV Administered With Other Antiretroviral Agents for the Treatment of HIV-1 Infection
The main objective of this study is to observe the long-term safety of elvitegravir (EVG) boosted with ritonavir (RTV) in combination with other antiretroviral (ARV) agents in participants who have completed a prior EVG+RTV…
- Trial name
- NCT00445146
- Testing
- EVG, RTV, ARV regimen
- Where
- 48 sites in United States, Puerto Rico
- Volunteers
- 192 people
- Sponsor
- Gilead Sciences
HIV Infections
Safety and Effectiveness of Giving Adefovir (Preveon) Plus Other Anti-HIV Drugs to HIV-Infected Patients Who Have Not Responded to Other Anti-HIV Drug Combinations
The purpose of this study is to see if it is safe and effective to give adefovir plus other anti-HIV drugs to HIV-infected patients who have failed other anti-HIV drug combinations.
- Trial name
- NCT00002398
- Testing
- Levocarnitine, Adefovir dipivoxil
- Where
- United States
- Sponsor
- Gilead Sciences
Mycoses, HIV Infections
A Study of Fluconazole in the Prevention of Fungal Infections in HIV-Infected Patients Living in Areas Where Fungal Infections Are Common
To compare the efficacy of fluconazole versus placebo in preventing the development of active coccidioidomycosis and other systemic fungal infections among HIV-infected patients with CD4 lymphocyte counts < 250 cells/mm3 who are…
- Conditions
- Mycoses, HIV Infections, Coccidioidomycosis
- Trial name
- NCT00002325
- Testing
- Fluconazole
- Where
- 3 sites in United States
- Sponsor
- Pfizer
HIV Infections
Emtricitabine Given Once A Day With Other Anti-HIV Drugs in Children With HIV
The purpose of this study is to see if emtricitabine is safe in children infected with HIV and to determine the best dose.
- Trial name
- NCT00017992
- Testing
- Lopinavir/Ritonavir, Emtricitabine, Stavudine
- Where
- 14 sites in United States, Argentina and 4 more
- Volunteers
- 100 people
- Sponsor
- Triangle Pharmaceuticals
Human Papillomavirus Infection
Colposcopy Findings Among Women With High Risk HPV Other Than HPV 16/18 and Normal Cytology
Abnormal cervical cytology was the most common reason for women being referred to the colposcopy unit. We prospectively included the women with negative cytology (negative for intraepithelial lesions or malignancy (NILM)) and…
- Trial name
- NCT04369339
- Testing
- Colposcopy
- Volunteers
- 185 people
- Sponsor
- Bezmialem Vakif University
HIV
A Study to Assess the Long-term Safety and Tolerability of TMC114/Rtv in HIV-1 Infected Participants After Rolling-over From Other TMC114 Trials
The purpose of this study was primarily to assess the long-term safety and tolerability of TMC114/rtv in addition to an individually optimized background antiretroviral therapy in HIV-1 infected participants.
- Trial name
- NCT02187107
- Testing
- TMC114, rtv
- Where
- 11 sites in Australia, Austria and 6 more
- Volunteers
- 52 people
- Sponsor
- Tibotec Pharmaceuticals, Ireland
HIV Infections
A Study of 141W94 in Combination With Other Anti-HIV Drugs
To determine the steady-state pharmacokinetics of 141W94 in combination with saquinavir, indinavir and nelfinavir after multiple oral dosing.
- Trial name
- NCT00002372
- Testing
- Indinavir sulfate, Amprenavir, Nelfinavir mesylate
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- Glaxo Wellcome
HIV Infections
Detection of Human Immunodeficiency Virus Type 1 (HIV-1) in Vaginocervical Secretions: Correlation With Clinical Status, Virologic and Immunologic Parameters, and the Presence of Other Infections
To correlate HIV-1 viral load in vaginocervical secretions (VCS), as measured by culture and nucleic acid detection, with that found in peripheral blood and HIV clinical status.
- Trial name
- NCT00000858
- Where
- 3 sites in United States
- Volunteers
- 350 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections, Central Nervous System Diseases
Central Nervous System Disease in HIV-infected Children on HAART
This study will examine how HIV affects the brain and nervous system, learning, and behavior in children on highly active antiretroviral therapy (HAART).
- Trial name
- NCT00110331
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- National Cancer Institute (NCI)
Viral Hepatitis C
Serious Game Interventions to Reduce Viral Hepatitis C Among PLWH-MSM
The study is aimed to provide high-risk, HIV-infection, men who have sex with men (MSM) with healthcare education regarding viral hepatitis C, through either serious game intervention or traditional online health education.
- Trial name
- NCT05751889
- Testing
- Serious Game, Traditional Health Education
- Where
- Taiwan
- Volunteers
- 1,320 people
- Sponsor
- National Taiwan University Hospital
HIV, Substance Use
Couples Health CoOp Plus
This study addresses HIV prevention and treatment for young couples living in Cape Town, South Africa, through a comprehensive biobehavioral multilevel approach-the Couples Health CoOp Plus (CHC+).
- Conditions
- HIV, Substance Use, Stigma, Social
- Trial name
- CHC+ (NCT05310773)
- Testing
- Community Stigma Awareness and Education Workshop, Couples Health CoOp Plus (CHC+)
- Where
- South Africa
- Volunteers
- 962 people, healthy volunteers welcome
- Sponsor
- RTI International
HIV Infections
A Study of 1592U89 Combined With Other Anti-HIV Drugs in Patients Who Have Taken Anti-HIV Drugs
To obtain preliminary evidence of antiretroviral activity of 1592U89 when administered in combination with other specific NRTI agents in NRTI experienced patients and to assess the safety and tolerance of multiple oral doses of…
- Trial name
- NCT00002364
- Testing
- Abacavir sulfate
- Where
- 8 sites in United States
- Volunteers
- 40 people
- Sponsor
- Glaxo Wellcome
Hepatitis C, HIV Infections
To Determine the Prevalence of HIV and Other Related Infections Such as Hepatitis C, Along With Associated Risk Behaviors, in Patients With Severe Mental Illness (SMI).
It is suspected, but not well documented, that persons with severe mental illness (SMI) represent a significant transmission source of serious infectious diseases.
- Conditions
- Hepatitis C, HIV Infections, Mental Disorders
- Trial name
- NCT00007709
- Where
- United States
- Sponsor
- US Department of Veterans Affairs