Clinical trials: Transmission
Human Immunodeficiency Virus, Tuberculosis
Usability Study of IeHS in Indonesia
Technology that has a particular focus on patients' needs and ease-of-use and -access plays a significant role in the development of e-health and m-health.
- Conditions
- Human Immunodeficiency Virus, Tuberculosis, Interpersonal Relations, Mobile Phone Use
- Trial name
- NCT04179344
- Testing
- Integrated e-healthcare services (IeHS) web-based app
- Where
- 3 sites in Indonesia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Bekasi City Public Hospital
Sexually Transmitted Diseases, Safe Sex
P3 (Prepared, Protected, emPowered)
P3 (Prepared, Protected, emPowered) is an interactive smartphone app for HIV-uninfected YMSM and YTW that utilizes social networking and game-based mechanics as well as a comprehensive understanding of what constitutes "best…
- Conditions
- Sexually Transmitted Diseases, Safe Sex, Adherence, Medication
- Trial name
- P3 (NCT03320512)
- Testing
- P3, P3+, Control
- Where
- 9 sites in United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Vector Transmission
Attractive Targeted Sugar Bait Trial in Mali
Globally, the female mosquitoes to be effective at transmitting malaria parasites, must have a number of characteristics including: abundance, longevity (individual mosquitoes must survive long enough after feeding on infected…
- Trial name
- NCT04149119
- Testing
- Attractive Target Sugar Baits (ATSB)
- Where
- Mali
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- University Clinical Research Center, Mali
HIV Infections
Safety of and Immune Response to an HIV Vaccine (VRC-HIVDNA009-00-VP) Administered With Interleukin-2/Immunoglobulin (IL-2/Ig) DNA Adjuvant in Uninfected Adults
This study will test the safety of and immune system response to a new HIV vaccine. The vaccine in this study is made from HIV DNA produced in a laboratory.
- Trial name
- NCT00069030
- Testing
- VRC-HIVDNA009-00-VP (Gag-Pol-Nef-multiclade-Env) with adjuvant VRC-ADJDNA004-IL2-VP
- Where
- 7 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Coronavirus
Viral Excretion in Contact Subjects at High/Moderate Risk of Coronavirus 2019-nCoV Infection. COVID-19.
In December 2019, a pneumonia due to a novel coronavirus (SARS-CoV-2) emerged in the city of Wuhan, in China. In a few weeks, the number of confirmed cases of SARS-CoV-2 infection has dramatically increased, with almost 150'000…
- Trial name
- Cov-CONTACT (NCT04259892)
- Testing
- 2019-nCoV PCR
- Where
- 16 sites in France, French Guiana
- Volunteers
- 324 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
HIV Infections
Evaluation of a Lopinavir/Ritonavir Monotherapy vs a Triple Therapy as Maintenance Regimens in HIV-1 Infected Patients
A 2-year multicenter, phase II/III, randomized active-controlled trial to evaluate the efficacy and tolerance of two maintenance strategies in HIV-1 infected patients with HIV RNA below 50 copies/mL : a monotherapy with…
- Trial name
- ANRS 140 DREAM (NCT00946595)
- Testing
- efavirenz/emtricitabin/tenofovir, lopinavir/ritonavir
- Where
- France
- Volunteers
- 420 people
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
Infections, Papillomavirus
Evaluation of Immunogenicity and Safety of Two 2-dose Human Papillomavirus (HPV) Vaccine Schedules in 9-14 Year Old Girls
This study has been designed to evaluate the immunogenicity and safety of GSK Biologicals' HPV-16/18 vaccine when administered according to alternative 2-dose schedules (0,6 months and 0,12 months) in healthy 9-14 year old…
- Trial name
- NCT01381575
- Testing
- GSK Biologicals' HPV vaccine 580299
- Where
- 33 sites in Canada, Germany and 3 more
- Volunteers
- 1,447 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
HIV Infections
Pharmacokinetics of Low Dose Raltegravir
The purpose of this study is to study and compare the pharmacokinetics profile of low dose raltegravir (RAL) (400mg OD and 800mg OD) and standard dose of 400mg BID in Thai HIV-infected patients.
- Trial name
- NCT01159132
- Testing
- raltegravir
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- The HIV Netherlands Australia Thailand Research Collaboration
Hiv
Study on PhArmacokinetics of First liNe Antiretrovirals in Healthy Breastfeeding Volunteers
No to little data exists on penetration of antiretroviral drugs in breastmilk. Too high concentrations may lead to infant toxicity and too low concentrations may lead to development of resistance in case the infant inadvertently…
- Trial name
- PANNA-B PK (NCT05648201)
- Testing
- Doravirine 100Mg Tab, Biktarvy 50/200/25 Tab
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
HIV Infections
HIV Risk Reduction in Youth in the Bahamas
This study will examine whether pairing a grade 6 in-school HIV education program and a parent training program will reduce prevalence of behaviors that present high risk of HIV infection in youth in the Bahamas.
- Trial name
- NCT00774592
- Testing
- FOYC, Goal for it (GFI), Wonderous Wetlands
- Where
- United States
- Volunteers
- 1,360 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Papillomavirus Infections
HPV Infections in Older Women
The purpose of this study is to determine risk factors for HPV infections in 25 to 65 year old women who report having used internet dating websites in the past year.
- Trial name
- NCT00743392
- Where
- United States
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- University of Washington
HIV Infections
Non-interventional Observational Study With Viramune® in HIV to Evaluate Gender Specific Data
The question that prompted this study is the extent to which results from clinical trials can be translated into everyday practice (external validity).
- Trial name
- NCT01134939
- Where
- 34 sites in Germany
- Volunteers
- 265 people
- Sponsor
- Boehringer Ingelheim
HIV Infections
A Clinical Trial to Evaluate the Immunogenicity of the Nonavalent Vaccine Against Human Papillomavirus in Men Infected by HIV Who Have Sex With Men. GESIDA 10017
Phase IV, open, multicenter and single-arm clinical trial designed to evaluate the immunogenicity of the HPV9v vaccine in men with HIV infection (HIV +) who have sex with men (MSM)
- Trial name
- GESIDA10017 (NCT03626467)
- Testing
- HPV9v
- Where
- 3 sites in Spain
- Volunteers
- 158 people
- Sponsor
- Fundacion SEIMC-GESIDA
Infection
Identigene STD Test Collection Kit Validation Study
The overall goal of the present study is to provide evidence of concordant test results using the Identigene STD Test Collection Kit for self-collection and transport of specimens to a qualified testing laboratory.
- Trial name
- NCT01471392
- Testing
- STD Diagnostic Kit (Identigene)
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Identigene
HIV, Gonorrhea
Improving Clinic Delivery of HIV-related Anal Health Services
This project will test ways to reduce stigma in healthcare settings so that more providers offer, and more patients receive, important anal sex-related HIV services, including anorectal sexually transmitted infection (STI)…
- Conditions
- HIV, Gonorrhea, Chlamydia, Anal Cancer Squamous Cell
- Trial name
- PEACHES 2 (NCT07464236)
- Testing
- PEACHES 2.0 Implementation Strategies
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Plasmodium Falciparum, Pregnancy Malaria
Clinical Performance of the HRP2 HS-RDT for Malaria Diagnosis in Pregnant Women
This is a cross-sectional and multicentre clinical trial to study the performance of the Histidine Rich Protein 2 (HRP2) highly sensitive rapid diagnostic test (HS-RDT) for the detection of malaria during pregnancy in low…
- Conditions
- Plasmodium Falciparum, Pregnancy Malaria, Diagnoses Disease
- Trial name
- HSRDT MiP (NCT03172221)
- Testing
- HS-RDT
- Where
- 2 sites in Colombia
- Volunteers
- 880 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
HIV Infection, Adverse Drug Reaction
Sustained Virological Suppression and Improvement of Adverse Events of Switching to Raltegravir Study
Switching from the ritonavir-boosted protease inhibitor component to raltegravir in stable HIV-infected adult patients receiving combination therapy will demonstrate improved clinical tolerability or lipid profiles with sustained…
- Conditions
- HIV Infection, Adverse Drug Reaction, Quality of Life
- Trial name
- TaISENWITCH (NCT01679964)
- Testing
- Raltegravir switch
- Where
- 7 sites in Taiwan
- Volunteers
- 107 people
- Sponsor
- Lin, Hsi-Hsun, M.D.
HIV
PREVAIL VIII: A CoHOrt Clinical, Viral, and ImmuNOlogic Monitoring Study of People Living With Retroviral Infection in Liberia (HONOR)
Background: There are many people living with human immunodeficiency virus (HIV) infection in Liberia. Most experts consider HIV an epidemic there.
- Trial name
- NCT03733093
- Where
- 4 sites in Liberia
- Volunteers
- 1,377 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Soil Transmitted Helminth (STH) Infections
Assessing the Safety and Efficacy of a Combination Therapy for STH in PSAC in Bangladesh
Background (brief): 1. Burden: Soil-transmitted helminth (STH) infections are a major public health problem, primarily affecting children.
- Trial name
- NCT07045493
- Testing
- A single dose of Albendazole 400mg + Ivermectin (200 µg/ kg) combination therapy, A single dose of 400 mg Oral Albendazole monotherapy
- Where
- Bangladesh
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
HIV/AIDS
Outcomes of HIV Infected Individuals After Ten Years on Antiretroviral Treatment
Study Title: Outcomes of HIV infected individuals after ten years on antiretroviral treatment Short Title/Study ID: ALT cohort Protocol Version and Date: Version 1.0 June 2013 Clinical Phase: NA Methodology: Prospective…
- Trial name
- ART Long Term (NCT02514707)
- Where
- Uganda
- Volunteers
- 1,000 people
- Sponsor
- Infectious Diseases Institute
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