Clinical trials: Transmission
Teen Pregnancy, Contraception Behavior
Evaluation of an Adolescent Pregnancy Prevention Program; Relationship Smarts+ With Lessons From Mind Matters
The goal of this randomized control trial (RCT) is to assess an innovative adolescent pregnancy prevention program among youth that are at the highest risk of adolescent pregnancy, to prevent pregnancy and Sexually Transmitted…
- Conditions
- Teen Pregnancy, Contraception Behavior, Sexually Transmitted Diseases, Reproductive Health
- Trial name
- NCT05889689
- Testing
- Relationship Smarts Plus & Mind Matters, Relationship Smarts Plus alone, Preparing Adolescents for Young Adulthood (PAYA).
- Where
- United States
- Volunteers
- 945 people, healthy volunteers welcome
- Sponsor
- Trinity Church Inc.
HIV Infections
A Study of DPC 817 in HIV-Infected Males
The purpose of this study is to evaluate DPC 817. The safety, dosages, and how the body responds to the drug will be studied.
- Trial name
- NCT00040274
- Testing
- DPC 817
- Where
- 2 sites in United States, Germany
- Volunteers
- 30 people
- Sponsor
- Pharmasset
HIV/AIDS
Project YES! Youth Engaging for Success
Youth-led strategies remain untested in clinic-based programs to achieve viral suppression (VS) and reduce self-stigma (feelings of worthlessness/shame) among adolescents and young adults (AYA) living with HIV in sub-Saharan…
- Trial name
- Project YES! (NCT04115813)
- Testing
- Project YES! Youth Engaging for Success
- Where
- Zambia
- Volunteers
- 276 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Gonorrhea, Chlamydia
Safer Sex Program for Young African-American Men
To evaluate the efficacy of the adapted program a randomized controlled trial enrolling 620 eligible African American men who have sex with men (MSM) will be conducted.
- Conditions
- Gonorrhea, Chlamydia, Trichomoniasis, Syphilis
- Trial name
- NCT01439503
- Testing
- Intervention
- Where
- United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- Richard Crosby
HIV Infection
Drug Interactions Among Anti-HIV Agents
This study examined the interactions of various drugs used to treat HIV infection in order to design larger studies of possible combinations for people who continue to have high viral levels despite combination therapy.
- Trial name
- NCT00001766
- Testing
- Amprenavir, Efavirenz, Abacavir, Nelfinavir, Ritonavir
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Implementation of Long-acting Cabotegravir + Rilpivirine Administration Out of "HIV Units".
This is a clinical trial whose main purpose is to evaluate the acceptability of the administration of LA CAB + extended-release RPV as perceived by patients in month 12 in multipurpose day hospital units versus specialized care…
- Trial name
- IMAdART (NCT06159894)
- Testing
- DAY HOSPITAL ARM, Specialist-Care arm
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Infections, Human Immunodeficiency Virus and Herpesviridae
A Single Dose Escalation Study to Investigate the Safety, Tolerability and Pharmacokinetics of Intramuscular and Subcutaneous Long Acting GSK1265744 in Healthy Subjects
A single dose escalation study to determine the safety, tolerability, and pharmacokinetic profile of intramuscular and subcutaneous injections of GSK1265744 long acting parenteral (LAP) in healthy subjects.
- Trial name
- NCT01756131
- Testing
- GSK1265744 injectable suspension
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Acquired Immunodeficiency Syndrome, HIV Infection
Safety and Survival of Genetically Modified White Blood Cells in HIV-Infected Persons - A Study in Identical Twin Pairs
This study will evaluate the safety of giving lymphocytes (white blood cells) containing a new gene to HIV-infected individuals and will determine how long the cells survive in the bloodstream.
- Trial name
- NCT00001353
- Testing
- Genetically Marked Syngeneic T Lymphocytes
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Seropositivity, Adherence, Medication
Supporting Health Behavior Among Persons Living With HIV Using Tech, MOST, and Behavioral Economics
The present study focuses on adult persons living with HIV in the New York City and Newark, New Jersey metropolitan areas who are not highly adherent to HIV medication and who do not evidence undetectable HIV viral load (the…
- Trial name
- SCAP2 (NCT04518241)
- Testing
- MI sessions, TMQQ, Type of compensation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- New York University
HIV-1-infection
Etravirine Plus 2 Analogs in HIV-infected Patients
The purpose of this study is to evaluate the virological and clinical efficacy of etravirine plus 2 active nucleos(t)ide reverse-transcriptase inhibitors (NRTIs) in HIV-infected patients.
- Trial name
- NCT01437241
- Where
- 11 sites in Spain
- Volunteers
- 175 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío
HIV Infections
Injectable Cabotegravir Compared to TDF/FTC For PrEP in HIV-Uninfected Men and Transgender Women Who Have Sex With Men
This study will evaluate the safety and efficacy of the injectable drug cabotegravir (CAB LA), for pre-exposure prophylaxis (PrEP) in HIV-uninfected cisgender men and transgender women who have sex with men (MSM and TGW).
- Trial name
- NCT02720094
- Testing
- Cabotegravir Oral Tablet, TDF/FTC tablets, CAB LA
- Where
- 43 sites in United States, Argentina and 5 more
- Volunteers
- 4,570 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections, Pneumococcal Infections
A Double-Blind Placebo-Controlled Trial of the Safety and Immunogenicity of a Seven Valent Pneumococcal Conjugate Vaccine in Presumed HIV-Infected Infants
To assess whether HIV-infected infants who receive a heptavalent pneumococcal conjugate vaccine have more local reactions at the site of injection and systemic reactions than placebo subjects.
- Trial name
- NCT00000829
- Testing
- Pneumococcal Vaccine, Polyvalent (23-valent), Pneumococcal Conjugate Vaccine, Heptavalent
- Where
- 33 sites in United States, Puerto Rico
- Volunteers
- 60 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infection, Aging
My Smart Age With HIV: Smartphone Self-assessment of Frailty
Understanding the complexity of aging and frailty in chronic HIV infection motivated Italian team members to begin to build a frailty index (FI) including 37 health variables at the Modena HIV Metabolic Clinic (MHMC).
- Trial name
- MySAwH (NCT02663856)
- Testing
- observational
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Modena and Reggio Emilia
Human Immunodeficiency Virus
Positive Attitudes Concerning Infant Feeding- a Questionnaire for Women Living With HIV
The PACIFY Study is a questionnaire for antenatal(third trimester) and postnatal(three months post delivery) Human Immunodeficiency Virus (HIV) positive women attending clinics in London and Brighton.
- Trial name
- PACIFY (NCT03294499)
- Testing
- Questionnaire
- Where
- 10 sites in United Kingdom
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Imperial College London
COVID-19
COVID-19 Household Transmission Study
This study will test and follow persons quarantined at home after testing positive for SARS-CoV-2 (COV) aged 18 years and older and their household members aged 1 year and older.
- Trial name
- CO-HOST (NCT04445233)
- Testing
- COVID-19 IgM-IgG Rapid Test
- Where
- United States
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV Infections
Increasing Condom Use in People at Risk for HIV Infection
This study will evaluate a new program designed to increase condom use in both women and men.
- Trial name
- NCT00080093
- Testing
- Individual feedback and specially-tailored manuals, General HIV information feedback and the best-available information
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
Dehydroepiandrosterone Effects on HIV-1 Replication
This study's purpose is to learn how dehydroepiandrosterone (DHEA) affects the HIV virus, the immune system, hormone levels, body composition and quality of life.
- Trial name
- NCT00065104
- Testing
- DHEA
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Sexually Transmitted Infections (STIs), Sexual Health Knowledge
Peer Education Based on Integrated Change Model on Nursing Students' STI-Related Behaviors
This study aims to compare the effectiveness of two peer education models on nursing students' behaviors, attitudes, and knowledge regarding sexually transmitted infections (STIs).
- Conditions
- Sexually Transmitted Infections (STIs), Sexual Health Knowledge, Health Behavior, Peer Education
- Trial name
- ICM-STI-PE (NCT07666152)
- Testing
- ICM-Based Peer Education Program, Standard Peer Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Human Papilloma Virus Infection, Carcinoma in Situ of Uterine Cervix
Community-Driven Cervical Cancer Prevention in Western Kenya
There are many challenges to implementation of cervical cancer prevention in resource-limited countries, despite evidence based screening and treatment strategies.
- Trial name
- NCT02124252
- Testing
- Community-based testing with standard linkage to care, Community-based HPV testing with enhanced linkage to care
- Where
- Kenya
- Volunteers
- 7,200 people, healthy volunteers welcome
- Sponsor
- Duke University
Surgical Wound Infection, Cross Infection
Reducing Intraoperative ESKAPE Transmission Through Use of a Personal Hand Hygiene System
The investigators hypothesize that the use of a personal hand hygiene system (SafeHavenTM) by anesthesia providers in the adult operating room, combined with a novel infectious pathogen tracking system (OR PathTrac) will decrease…
- Trial name
- ESKAPE (NCT04900298)
- Testing
- SafeHaven Automated Hand Hygiene Device
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
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