Clinical trials: Transsexualism
Transgenderism, Kidney Diseases
Effect of Hormone Therapy on Renal Function
The purpose of this study is to understand the effects of testosterone or estradiol on kidney function in transgender adolescents and young adults.
- Conditions
- Transgenderism, Kidney Diseases, Kidney Injury
- Trial name
- NCT04482920
- Testing
- p-aminohippurate clearance study, Iohexol infusion
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Colorado, Denver
Fertility Preservation, Transgender
The Determinants of Fertility Preservation in TRANSgender Patients.
The study is monocentric, retrospective, non-interventional and does not involve human subjects. The main objective is to compare the profiles of transgender patients who undergo fertility preservation with those who do not.
- Conditions
- Fertility Preservation, Transgender, Transgenderism
- Trial name
- FP-TRANS (NCT06074796)
- Testing
- No intervention.
- Where
- France
- Volunteers
- 230 people
- Sponsor
- Central Hospital, Nancy, France
Transgenderism
Is Bioimpedance Analysis Accurate in Transgender Males?
Accurate fat mass and muscle mass assessment is an informative marker of an individual's health. However, the optimal method for assessing body composition in transgender males remains to be determined.
- Trial name
- NCT05728853
- Testing
- Assessment of body composition
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Aalborg University Hospital
Transgenderism
Sociological Study of the Life Courses of Young TRANSgender Patients
The number of people consulting for a request related to trans identity is increasing sharply. The study monocentric qualitative study of discursive material aims to describe the diversity of practices and discourses mobilized by…
- Trial name
- ParTransRep (NCT06221163)
- Testing
- collection of biographical and sociological data
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Transgenderism, Fertility Issues
Transgender Caregivers' and Patients' Representations of Parenthood as Part of a Fertility Preservation Pathway
This research aims to understand the impact of fertility preservation consultation on transgender patients' projection and how the possibility of preserving gametes influences transgender people's transition paths, parenthood…
- Trial name
- TransFert (NCT06218446)
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gender Incongruence, Transgenderism
Effect of Transgender Therapy on Muscle, Fat and Tissue Receptors
The purpose of this research is to find out if hormone therapy in transgender subjects' changes hormone receptors in blood, muscle and fat; fat production; muscle production; and inflammation processes.
- Trial name
- NCT04551144
- Testing
- testosterone cypionate, Estradiol Valerate
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- St. Louis University
Transgenderism, Gender Dysphoria
Effectiveness of Speech Therapy in Trans Women.
One of the greatest hurdles in the transition of transgender persons is that voice, speech and communication are not congruent with the desired gender.
- Conditions
- Transgenderism, Gender Dysphoria, Speech Therapy, Voice Disorder Due to Transsexualism
- Trial name
- NCT04708600
- Testing
- Pitch Elevation Therapy, Articulation Resonance Therapy
- Where
- Belgium
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University Ghent
Acne, Transgenderism
Factors Associated With the Acne Severity Among Transmen Population: a Cross-sectional Study
The goal of this observational cross-sectional study is to identify factors associated with severity of acne in Thai transmen receiving masculinizing hormone therapy.
- Trial name
- NCT06149065
- Testing
- Testosterone
- Where
- Thailand
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Transgenderism, HIV Infections
Transgender Men's Perspectives on HIV Risk and HIV Prevention Interventions
The goal of this pilot study is to gather and analyze qualitative data from focus groups with Transgender men who have sex with men (TMSM) to learn more about the life experiences unique to TMSM that influence their attitudes and…
- Trial name
- NCT05666102
- Testing
- Transgender men's perspectives on HIV risk and HIV prevention interventions
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Breast Cancer, Gynecomastia
Effect of Suture Material on Postoperative Nipple Areolar Complex Widening
This will be a single-blinded study where participants are blinded to the suture type but the surgeon will draw a random, unmarked envelope containing the designated suture type at the start of the surgery.
- Conditions
- Breast Cancer, Gynecomastia, Transgenderism, Breast Asymmetry
- Trial name
- NCT06070324
- Testing
- Breast surgery, Suturing of surgical incision
- Volunteers
- 180 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hiv, Transgenderism
Microeconomic Intervention to Reduce HIV Transmission in Economically Disadvantaged Transgender Women
The purpose of this research study is to learn more about the economic situations, discrimination experiences, and risk behaviors of transgender women.
- Trial name
- NCT04275310
- Testing
- Microeconomic Intervention
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Transgenderism, Catheter Related Complication
Safe Access for Bladder Entry in Transgender Men Following Penile Reconstruction
Inserting a urinary catheter in transgender men following penile reconstruction is difficult and usually requires specialist input.
- Trial name
- SAFE (NCT04454970)
- Testing
- Urethrotech Urethral catheterisation device (UCD), Bardia Aquafil long term catheter
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- University College, London
Papillomavirus Infection, Transsexualism
HPV Prevalence in Transpersons - a Prospective Study
In this study, Human Papilloma Virus (HPV) prevalence will be determined once in the urine of 200 trans people. In addition, subjects will be asked to complete a questionnaire about their sexual orientation, which is adapted from…
- Trial name
- NCT04864951
- Testing
- Colli-Pee urine collection device, Survey
- Where
- 2 sites in Austria, Slovenia
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Sophie Pils
Transgenderism, Gender Identity
Quality of Life of Transgender People - Implementation and Monitoring of an Online Cohort (e-QoL-Trans)
Transgender people have an identity or an expression gender that differs from the sex assigned to them at the birth. Transgender people and their needs remain misunderstood, and more generally by society.
- Trial name
- e-QoL-Trans (NCT05761678)
- Testing
- Questionnaire quality of life
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Transgenderism, Clotting Disorder
Coagulation and Fibrinolysis of Estradiol in Transwomen
The specific aim for our study is to measure coagulation system activation and fibrinolysis following transdermal versus sublingual versus oral estradiol versus in transgender women.
- Trial name
- NCT05387577
- Testing
- Estradiol Tablets, Transdermal patch
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Gender Dysphoria, Gender Identity Disorder
i2TransHealth: Interdisciplinary, Internet-based Trans Health Care
i2TransHealth is a randomized controlled trial that investigates the outcomes of an internet-based health care approach for transgender and gender diverse (TGD) people.
- Conditions
- Gender Dysphoria, Gender Identity Disorder, Transsexualism, Gender Identity
- Trial name
- NCT04290286
- Testing
- i2TransHealth
- Where
- Germany
- Volunteers
- 186 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Transgenderism
Expectations and Beliefs of Transgender People Regarding Hormonal Treatment
Hormonal treatment of gender dysphoria can have repercussions on metabolism, cardiovascular system and fertility and represents à potential oncological risk. According to the recommendations of the Endocrine society.
- Trial name
- NCT05474768
- Testing
- no intervention
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Central Hospital, Nancy, France
Transgenderism
Extracellular Vesicles and Endothelial Function in Transgender Subjects
Cardiovascular diseases are the leading cause of mortality. In women, the prevalence of cardiovascular diseases is lower and the presentation of coronary events often atypical.
- Trial name
- Evinge (NCT04971447)
- Testing
- gender affirming hormonal treatment in transgender men, gender affirming hormonal treatment in transgender women
- Volunteers
- 136 people
- Sponsor
- Central Hospital, Nancy, France
Transsexualism, Surgery
Use of an External Erectile Device in Transgender Man Following Phalloplasty
The purpose of this study is to test whether an external erectile prosthesis (The Elator™) is a feasible alternative to internal erectile prostheses for transgender men who have undergone a phalloplasty with glansplasty and wish…
- Conditions
- Transsexualism, Surgery, Sex Behavior, Erectile Dysfunction
- Trial name
- ProstHEsis (NCT03823014)
- Testing
- Elator
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Transgenderism
Evaluation of an Adaptative, Multidisciplinary, Reach-out Program, Facilitating Pre Exposition HIV Prophylaxis (PrEP) Prescription and Retention in Care, in a Group of Trans Womens (TW) at High Risk of HIV Infection.
Evaluation of an adaptative, multidisciplinary, reach-out program, facilitating pre exposition HIV prophylaxis (PrEP) prescription and retention in care, in a group of trans womens (TW) at high risk of HIV infection.
- Trial name
- PrEP à porter (NCT05415930)
- Testing
- Psychosocial assistance, Medical care, Legal-Administrative Assistance
- Volunteers
- 100 people
- Sponsor
- Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba