Clinical trials: Transurethral Resection of Bladder Tumor
Urinary Bladder Cancer
Histopathological Findings in En-Bloc vs Conventional Transurethral Resection of Bladder Tumors.
This study is designed to determine whether en-bloc TURBT provides superior histopathological quality and clinical outcomes compared to conventional TURBT in medium-sized bladder tumors.
- Trial name
- NCT07259798
- Testing
- En bloc TURBT using a bipolar Karl-Storz resectoscope system fitted with a specialized "flat" resection loop, Bipolar piecemeal TURBT using the same bipolar Karl-Storz resectoscopic platform
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Bladder Cancer
Effect of Fresh Gas Flow on Emergence Time
The purpose of this study is to evaluate the effect of fresh gas flow on emergence time in patients undergoing transurethral resection of bladder tumor.
- Trial name
- NCT05376631
- Testing
- Fresh gas flow of 5 L/min, Fresh gas flow of 10 L/min
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Asan Medical Center
Bladder Cancer, Covid19
The Effect of the COVID-19 Pandemic on Primary Bladder Cancer Presentations
In this study, investigators aim to reveal how the COVID-19 pandemic process affects primary bladder cancer presentations, tumor stages and degrees, the time elapsed between diagnosis and intervention, tumor recurrence and…
- Trial name
- NCT04900259
- Testing
- COVID-19 pandemic
- Where
- Turkey (Türkiye)
- Volunteers
- 183 people
- Sponsor
- Ankara Training and Research Hospital
Bladder Cancer, Bladder Cancer Stage I
Loop Resection or Cold-cup Biopsy? A Study Comparing the Accuracy of Muscle Samples During Bladder Tumor Surgery
In this report the investigators compared two deep muscle sampling methods (Loop resection and Cold-Cup Biopsy) during endoscopic resection of bladder tumors for patients with suspected bladder cancer in Tygerberg hospital.
- Conditions
- Bladder Cancer, Bladder Cancer Stage I, TURBT
- Trial name
- NCT06796413
- Testing
- Loop Resection or Cold-cup biopsy
- Where
- South Africa
- Volunteers
- 120 people
- Sponsor
- University of Stellenbosch
Bladder Cancer
Longer-term Recurrence Rates in Patients With Bladder Cancer After Hexvix (Cysview)Fluorescence Cystoscopy/TURB
The study is intended to investigate whether the improved initial detection and resection of bladder cancer lesions in patients with non-muscle invasive bladder cancer with Hexvix (Cysview) fluorescence cystoscopy/TURB will lead…
- Trial name
- NCT01166230
- Where
- 24 sites in United States, Austria and 3 more
- Volunteers
- 551 people
- Sponsor
- Photocure
Bladder (Urothelial, Transitional Cell) Cancer
A Clinical Study Evaluating the Efficacy and Safety of Disitamab Vedotin Combined With PD-1 Inhibitor and Radiotherapy as Bladder-preserving Therapy in Patients With Localized HER2-high Expressing Muscle-invasive Bladder Urothelial Carcinoma Following Maximal Transurethral Resection
This is a prospective, open label, multicenter clinical study of vediximab combined with PD-1 and radiation therapy for bladder preservation in MIBC patients with HER-2 high expression (IHC 2+or 3+), conducted in accordance with…
- Trial name
- DECIDING (NCT07142200)
- Testing
- Disitamab Vedotin, PD-1 inhibitor, radiotherapy
- Where
- China
- Volunteers
- 45 people
- Sponsor
- RenJi Hospital
Bladder Cancer
Diagnostic Performance and Predictive Capacity of Immediate Urine Cytology After Transurethral Resection of Non-Muscle Invasive Bladder Cancer; A Prospective Study
The current study aimed at prospectively assessing the performance of IUC as a predictive tool for residual tumor after primary TURBT of NMIBC, and possible future recurrence.
- Trial name
- NCT04194112
- Testing
- immediate urine cytology
- Volunteers
- 198 people
- Sponsor
- Mansoura University
Bladder Cancer, Transurethral Resection of the Bladder
Relevance of the Urine Bacterial Culture Performed Before TransUrethral Resection of the Bladder for Post-operative Febrile Urinary Tract Infections Prevention: a Non-inferiority Randomized Controlled Trial
The main objective of the study is to demonstrate that not performing a systematic UC before the TURB procedure is non-inferior to performing a systematic UC in terms of the incidence of febrile UTIs during the first 30…
- Conditions
- Bladder Cancer, Transurethral Resection of the Bladder, Urinary Tract Infection Bacterial
- Trial name
- RUPTURE (NCT07463963)
- Testing
- Urine bacterial Culture (UC), No intervention before TURB surgery
- Where
- 15 sites in France
- Volunteers
- 2,600 people
- Sponsor
- Poitiers University Hospital
Urinary Bladder Neoplasm
Holmium Versus Bipolar en Bloc Transurethral Resection of Urothelium Tumor of the Urinary Bladder
En bloc resection of bladder tumors (ERBT) may improve staging quality and perioperative morbidity and influence tumour recurrence
- Trial name
- NCT04576286
- Testing
- Holmium versus Bipolar en bloc transurethral resection
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Bladder (Urothelial, Transitional Cell) Cancer, Nonmuscle Invasive Bladder Cancer
Implications of Post-Operative Irrigation Fluid's Osmolarity on the Recurrence of Non-Muscle Invasive Bladder Cancer Following Transurethral Resection
This randomized controlled trial will evaluate the efficacy of three bladder irrigation solutions - distilled water (DW), normal saline (NS), and hypertonic saline (HS) - as continuous bladder irrigation (CBI) following…
- Conditions
- Bladder (Urothelial, Transitional Cell) Cancer, Nonmuscle Invasive Bladder Cancer, Irrigation, Hypertonic Saline
- Trial name
- NCT07279792
- Testing
- Continuous Bladder Irrigation with distilled water, Continuous Bladder Irrigation with normal saline, Continuous Bladder Irrigation with hypertonic saline
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Ain Shams University
Bladder Urothelial Carcinoma, TURBT
Storz Professional Image Enhancement System Versus White Light Imaging Assisted TURBT for Treatment of NMIBC
Compare the therapeutic utility of SPIES assisted TURB with WLI assisted TURB in patients with non-muscle invasive bladder cancer.
- Conditions
- Bladder Urothelial Carcinoma, TURBT, Bladder Neoplasm, Cystoscopy
- Trial name
- NCT03138824
- Testing
- SPIES assisted TURBT, WLI assisted TURBT
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Bladder Cancer, Urothelial Carcinoma
A Phase 3 Study of UGN-102 for Low-Grade Intermediate-Risk Non-Muscle Invasive Bladder Cancer
This global, randomized, controlled, open-label Phase 3 study was designed to assess the long-term efficacy and safety of UGN-102 (mitomycin) for intravesical solution with or without (±) transurethral resection of bladder tumors…
- Conditions
- Bladder Cancer, Urothelial Carcinoma, Urothelial Carcinoma Bladder
- Trial name
- ATLAS (NCT04688931)
- Testing
- UGN-102, TURBT
- Where
- 139 sites in United States, Bulgaria and 8 more
- Volunteers
- 282 people
- Sponsor
- UroGen Pharma Ltd.
Bladder Cancer
Combination Chemotherapy in Treating Patients With Stage II Bladder Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00002919
- Testing
- filgrastim, cisplatin, doxorubicin hydrochloride
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Bladder Cancer
A Phase 1/2 Study of HS-410 in Patients With Non-Muscle Invasive Bladder Cancer After TURBT
Phase I/II study: Phase 1 is an open-label, safety study, patients who previously received 3-6 instillations of weekly intravesical Bacillus Calmette-Guerin (BCG) induction therapy (as standard of care) followed by low dose…
- Trial name
- NCT02010203
- Testing
- HS-410, BCG
- Where
- 19 sites in United States
- Volunteers
- 104 people
- Sponsor
- Heat Biologics
Bladder Cancer, Bladder Neoplasm
Bipolar Versus Mono-polar Needlescopic En Bloc TUR-BT
Non-muscle invasive bladder cancers (NMIBC) compose about 80% of bladder tumors. the stranded treatment of these tumors is TURBT. en bloc resection of NMIBC yields better mascularis propria with better oncological outcomes
- Trial name
- NCT04839029
- Testing
- Bipolar En bloc TURBT, Monopolar En bloc TURBT
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Benha University
Transurethral Resection of Bladder Tumor, Transurethral Resection of the Prostate (TURP)
Effect of Cyclic Sighing Breathing Exercise on CRBD, Pain, and Sleep Quality in Patients Undergoing TUR
Transurethral resection (TUR) is a common minimally invasive surgical procedure for lower urinary tract diseases. However, postoperative urinary catheterization often causes catheter-related bladder discomfort (CRBD) and pain due…
- Conditions
- Transurethral Resection of Bladder Tumor, Transurethral Resection of the Prostate (TURP), Transurethral Resection of the Bladder
- Trial name
- NCT07843602
- Testing
- Cyclic Sighing Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Mersin University
Hemorrhage
Safety and Efficacy of Intravenous Tranexamic Acid in Endoscopic Transurethral Resections in Urology
Transurethral resection of the prostate (TURP) represents the gold standard in the operative management of benign prostatic hyperplasia (BPH) and the transurethral resection of bladder tumor (TURBT) is the first-line surgical…
- Trial name
- NCT02653261
- Testing
- Tranexamic Acid
- Where
- Tunisia
- Volunteers
- 131 people
- Sponsor
- University Tunis El Manar
Bladder Cancer
A Study of Comparing Effects of Thulium Laser en Bloc Resection and Electrical Transurethral Resection of the Non-muscle Invasive Bladder Cancer
This study is to verify the short-term efficacy and long-term prognosis of thulium laser resection compared with conventional transurethral resection of non-muscular invasive bladder cancer.
- Trial name
- NCT02951078
- Testing
- Thulium Laser en Bloc Resection of bladder tumor, Electrical transurethral resection of bladder tumor
- Volunteers
- 172 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Non Muscle Invasive Bladder Cancer, Urologic Cancer
A Study of Adjuvant Cretostimogene Grenadenorepvec for Treatment of Intermediate Risk NMIBC Following TURBT
This is a Phase 3, open-label, randomized trial designed to evaluate the RFS of TURBT followed by cretostimogene grenadenorepvec versus TURBT followed by surveillance for the treatment of participants with IR-NMIBC.
- Conditions
- Non Muscle Invasive Bladder Cancer, Urologic Cancer, Bladder Cancer, Urothelial Carcinoma
- Trial name
- NCT06111235
- Testing
- Cretostimogene Grenadenorepvec, n-dodecyl-B-D-maltoside
- Where
- 95 sites in United States, Canada
- Volunteers
- 367 people
- Sponsor
- CG Oncology, Inc.
Bladder Cancer
The Difference of Two Year Recurrence Rate According to Anesthetic Method During Transurethral Resection of Bladder Mass in Patients With Non-muscle Invasive Bladder Cancer: Prospective, Randomized, Clinical Phase II Study
The investigators compare the recurrence rate difference between two years after transurethral resection of the bladder tumor according to the method of anesthesia. Anesthetic methods are general anesthesia and spinal anesthesia.
- Trial name
- NCT03597087
- Testing
- Anesthesia before transurethral resection of the bladder tumor, Anesthesia
- Where
- South Korea
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital