Clinical trials: Transversus Abdominis Plane Block
Colorectal Surgery, TAP Blocks
TAP Block Catheters vs Liposomal Bupivacaine for Pain Control After Colorectal Surgery
This is a prospective randomized study designed to compare the pain control from a single shot of liposomal bupivacaine (Exparel) against transversus abominus plane (TAP) catheters with ropivicaine bolus in patients undergoing…
- Trial name
- NCT03080142
- Testing
- Exparel, Ropivacaine
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of California, Davis
Opioid Use, Pain, Acute
TAP Block Using Liposomal Bupivacaine for Post-cesarean Delivery Analgesia- Walking Towards Recovery
The TAP block offers analgesia by blocking the sensory nerves of the anterior abdominal wall. The procedure is performed under ultrasound guidance, after identification of the external oblique, internal oblique and transverse…
- Trial name
- NCT04393207
- Testing
- Liposomal bupivacaine (LB), Dexamethasone and methylprednisolone (CG), Control group (Bupivacaine)- (BPG)
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Yale University
Colonic Cancer, Rectal Cancer
Transversus Abdominis Plane (TAP) Block for Postoperative Analgesia After Laparoscopic Colonic Resection
Laparoscopic (key-hole) large bowel resection is a minimally invasive procedure when compared to open large bowel resection, but is still associated with a significant amount of pain and discomfort.
- Conditions
- Colonic Cancer, Rectal Cancer, Colonic Diverticulum, Ulcerative Colitis
- Trial name
- NCT01339273
- Testing
- Ultrasound guided Transversus Abdominis Plane (TAP) bock, Local anaesthetic infiltration of laparoscopic port sites
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- Oxford University Hospitals NHS Trust
Abdominal Surgery
Comparing TAP Blocks Bupivacaine, and Placebo for Plane
The study will prospectively compare the analgesic efficacy of TAP blocks with liposomal bupivacaine, plain bupivacaine, and placebo in patients who are scheduled for major abdominal surgery.
- Trial name
- CLEVELAND (NCT04685876)
- Testing
- Liposomal bupivacaine, Plain bupivacaine, Normal saline
- Where
- United States
- Volunteers
- 285 people
- Sponsor
- Edward Mascha
Acute Pain
TAP Block With Liposomal Bupivacaine Versus Bupivacaine in Robotic Hysterectomy
The purpose of the study is to compare pain control after robotic hysterectomy surgery using either liposomal bupivacaine or Bupivacaine when injected during a transversus abdominis plane (TAP) block.
- Trial name
- NCT02289079
- Testing
- Bupivacaine, liposomal bupivacaine
- Volunteers
- 60 people
- Sponsor
- University of Minnesota
C-Section, Pain Management
Evaluate the Safety and Efficacy of EXPAREL When Administered Via Infiltration Into the TAP vs. Bupivacaine Alone in Subjects Undergoing Elective C-Sections
Primary objective: The primary objective of this study is to compare total opioid consumption through 72 hours following EXPAREL+bupivacaine HCl infiltration into the transversus abdominis plane (TAP) after spinal anesthesia to…
- Trial name
- C-Section (NCT03176459)
- Testing
- Exparel + Bupivacaine, Bupivacaine
- Where
- 12 sites in United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Pacira Pharmaceuticals, Inc
Colorectal Disease
Evaluation of a TAP Block Given During Laparoscopic Colorectal Surgery to Help Control Pain
Patients experience pain after surgery mostly from their abdominal wounds, even when those wounds are small. Decreasing that pain has many benefits.
- Trial name
- TAP Block (NCT01731782)
- Testing
- bupivacaine
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Pain
Comparison of Exparel to Bupivacaine With Dexamethasone in TAP Block
The purpose of this study is to compare the efficacy and duration of bupivacaine extended-release liposome injection (Exparel) versus bupivacaine with dexamethasone in transversus abdominis plane (TAP) blocks for patients…
- Trial name
- TapBlock (NCT02179892)
- Testing
- Bupivacaine Extended-Release Liposome Injection (Exparel), Bupivacaine and Dexamethasone Injection, IV Acetaminophen
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Colette Curtis MD
Laparoscopic Sleeve Gastrectomy, Subcostal Transversus Abdominis Plane Block
Unilateral TAP Block for Laparoscopic Gastric Sleeve Surgery
The study team will be assessing if the unilateral subcostal transversus abdominis plane (TAP) block can decrease pain and improve outcomes following laparoscopic sleeve gastrectomy surgeries.
- Trial name
- NCT03856788
- Testing
- Saline, Bupivacaine
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pain, Postoperative, Crohn Disease
Intraoperative TAP Block With Bupivacaine/Dexamethasone Against Liposomal Bupivacaine (Exparel®)
Traditionally, opioids are heavily utilized in treating postoperative pain but they are associated with numerous side effects. The use of the transversus abdominis plane (TAP) blocks have become standard practice to extend the…
- Conditions
- Pain, Postoperative, Crohn Disease, Inflammatory Bowel Diseases, Colorectal Cancer
- Trial name
- TINGLE (NCT03723447)
- Testing
- Liposomal bupivacaine, Bupivacaine/epinephrine/dexamethasone
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Cedars-Sinai Medical Center
Pain, Postoperative, Anesthesia
Transversus Abdominal Plane Block at Total Laparoscopic Hysterectomy: Effect on Quality of Recovery
The Transversus Abdominal Plane (TAP) block has been used with good success to decrease postoperative pain following laparatomy.
- Trial name
- TAP (NCT01479270)
- Testing
- TAP Block
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Breast - Female
Transversus Abdominis Plane Block in Microsurgical Breast Recon w/Abdominal Free Flap in Breast CA
The primary objective is to determine if pre-operative transversus abdominis plane (TAP) nerve blocks by continued infusion of local anesthetic post-operatively affects post-operative narcotic usage, as compared to a placebo TAP…
- Trial name
- NCT02601027
- Testing
- Transversus Abdominis Plane (TAP) block, Nimbus Infusion Pump IV Administration, Bupivacaine infusion
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Stanford University
Post Operative Pain
Ultrasound-guided Transversus Abdominis Plane Block After Hysterectomy
In this randomized, controlled, observer-blinded study we plan to evaluate ultrasound-guided transversus abdominis plane (TAP) block for postoperative pain management in patients undergoing abdominal hysterectomy.
- Trial name
- TAP (NCT01153503)
- Testing
- TAP block
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Prostate CA
Evaluation of Addition of Dexamethasone to Transversus Abdominis Plane (TAP) Peripheral Nerve Block
Transversus abdominis plane (TAP) blocks are increasingly being performed after abdominal surgery to provide post operative analgesia.
- Trial name
- NCT01303003
- Testing
- Dexamethasone, TAP block
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Steward St. Elizabeth's Medical Center of Boston, Inc.
Anesthesia
Transversus Abdominis Plane Block in Children Undergoing Open Pyeloplasty Surgery
The purpose of this study is to evaluate the effectiveness of transversus abdominis plane (TAP) block in reducing postoperative opioid requirements and pain after open pyeloplasty surgery in children.
- Trial name
- NCT01243593
- Testing
- Transversus Abdominis Plane Block, Standard Anesthesia
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- The Hospital for Sick Children
Opioid Use, Pain, Postoperative
Standard Bupivacaine vs Liposomal Bupivacaine in Colorectal Patients
The transversus abdominis plane (TAP) block can be used to reduce pain in patients who get abdominal surgery. TAP blocks are given with a local anesthetic.
- Conditions
- Opioid Use, Pain, Postoperative, Colectomy, Colorectal Surgery
- Trial name
- NCT03638635
- Testing
- Bupivacaine, Bupivacaine liposome
- Where
- 6 sites in United States
- Volunteers
- 63 people
- Sponsor
- Inova Health Care Services
Postoperative Pain
Transversus Abdominis Plane (TAP) Block Laparoscopic Hysterectomy
The transversus abdominis plane (TAP) block involves the sensory nerve supply of the anterior -lateral abdominal wall where the T7-12 intercostal nerves, ilioinguinal, iliohypogastric and the lateral cutaneous branches of the…
- Trial name
- TAP HYS (NCT01074229)
- Testing
- Drug .5% Ropivacaine, 20 cc of 0.25% ropivacaine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Northwestern University
Postcesarean Analgesia
Transversus Abdominis Plane Block Versus Wound Infiltration for Postcesarean Analgesia
The study will compare the analgesic efficacy of transversus abdominis plane block and wound infiltration in parturients undergoing cesarean delivery under spinal anesthesia.
- Trial name
- NCT02691572
- Testing
- Spinal anesthesia, Intrathecal bupivacaine, Intrathecal fentanyl
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Anesthesia, Ostomy
Transversus Abdominis Plane Block in Children Undergoing Ostomy Surgery
The primary objective of this study is to determine if the use of Transversus Abdominis Plane (TAP) blocks reduce early postoperative opioid requirements.
- Trial name
- NCT01136668
- Testing
- Transversus Abdominis Plane Block, Standard
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- The Hospital for Sick Children
Pain Control
Efficacy of TAP Block in Cesarean Section Patients
TAP Block done with 2 different concentrations of bupivacaine and placebo
- Trial name
- NCT03493828
- Testing
- TAP block using Bupivacaine 0.5%, TAP block using Bupivacaine 0.25%, TAP block using Normal Saline
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- New York Presbyterian Brooklyn Methodist Hospital