Clinical trials: Trauma, Nervous System
Spinal Cord Injuries
High Intensity Training for Neurological Injury Using Overground Exoskeletons in Inpatient Rehabilitation
The purpose of this study is to see if it's possible to reach high cardiovascular intensity training parameters (exercise at a rate that elevates heart rate to the level recommended for improving strength and endurance) while…
- Trial name
- HIT Exo IP (NCT04973852)
- Testing
- Ekso
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- The University of Texas Health Science Center, Houston
Spinal Cord Injuries, Reliability
Reliability and Validity of the Spinal Cord Injury Secondary Conditions Scale
People living with spinal cord injury (SCI) experience a range of secondary health conditions that impact their quality of lives.
- Conditions
- Spinal Cord Injuries, Reliability, Validity
- Trial name
- NCT05935943
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Brain Injury
Effects of Viral Reactivation on Outcomes of Brain-injured Patients ( IBIS-VIRUS)
Morbidity and mortality of ICU patients is increased by the development of a "immunosuppression" systemic (IS). This IS develops in the early hours of hospitalization and is responsible for severe infections, including viral…
- Trial name
- IBIS-VIRUS (NCT02003196)
- Where
- France
- Volunteers
- 375 people
- Sponsor
- Nantes University Hospital
Stroke, Spinal Cord Injuries (Complete and Incomplete)
EMG-Directed Virtual-Reality Training for Motor Stroke Rehabilitation
This study is testing whether rehabilitation using muscle activity signals can help improve arm and hand movement in people after stroke or spinal cord injury.
- Trial name
- NCT07705256
- Testing
- Visual EMG feedback with vibrotactile feedback, Visual EMG feedback
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Imperial College London
Post Operative Pain, Femur Fracture
Volume Dependent Effect of Pericapsular Nerve Block
In PENG block technique, the local anesthetic agent is injected between the psoas tendon and the pubic ramus to block the sensory branches of the nerves which innervates the hip capsule for providing analgesia without causing…
- Trial name
- NCT05256056
- Testing
- Bupivacain
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Spinal Cord Injuries
AMPLIFY Study: Transcutaneous Spinal Direct Current Stimulation to Enhance Locomotor Rehabilitation After SCI
Locomotor training (LT) facilitates recovery of spinal locomotor networks after incomplete spinal cord injury (ISCI), but walking impairments persist.
- Trial name
- NCT05700942
- Testing
- High Dose Intervention-tsDCS, Low Dose Intervention-tsDCS
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Florida
Brain Injury
Combining Observational and Physiologic Sedation Assessment Tools
When a physiologic tool to measure the patient's hypnotic state is added to current practice tools is there a decrease in the amount of drug the patient receives.
- Trial name
- COST (NCT00538369)
- Testing
- Ramsay Scale, Bispectral index monitor
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Duke University
Orbital Fractures
Orbital Fractures Measurement: Intraoperative Versus Computed Tomography (CT) Scan
Purpose to compare the orbital fracture size measured by orbital CT scan and compare it to the actual orbital fracture size intraoperatively in patients who needed surgical intervention to correct the fracture.
- Trial name
- NCT01464541
- Testing
- operative fracture size vs CT fracture size, orbital fracture intraoperative measurement
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- HaEmek Medical Center, Israel
Autonomic Dysreflexia
Fesoterodine for Amelioration of Autonomic Dysreflexia (AD) Following Spinal Cord Injury (SCI)
This study will be investigating the effects of fesoterodine on autonomic dysreflexia (AD) in patients with spinal cord injuries (SCI).
- Trial name
- NCT02676154
- Testing
- Fesoterodine
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of British Columbia
Neurogenic Bowel
Improving Bowel Function and Quality of Life After Spinal Cord Injury
Bowel dysfunction is consistently rated as one of the most common complications affecting daily life for individuals with spinal cord injury.
- Trial name
- NCT03949660
- Testing
- Stimulation for blood pressure without stand, Stimulation for blood pressure with stand, Stimulation for trunk and core without stand
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- University of Louisville
Ambulatory Surgery, Laparoscopy
Implementation of 23 Hour Surgery Model in a Tertiary Hospital
Extended day surgery or 23 h surgery (23-hour surgery) is a surgical model where patients arrive to the hospital from home at the day of surgery, are operated and recover in a 23 h surgery unit.
- Conditions
- Ambulatory Surgery, Laparoscopy, Shoulder Impingement Syndrome, Ovarian Cysts
- Trial name
- Herko (NCT04142203)
- Testing
- 23 h surgery
- Where
- Finland
- Volunteers
- 993 people
- Sponsor
- Kuopio University Hospital
Shoulder Injury
Blood Flow Restriction Therapy Following Acute Shoulder Injury Patients
Atrophy and weakness of the shoulder are a common problem following treatment of a number of shoulder and elbow pathologies. Even with relatively short periods of reduced activity, the magnitude of muscle loss can be quite…
- Trial name
- BFR (NCT06223373)
- Testing
- Blood Flow Restriction
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Wake Forest University Health Sciences
Inguinal Herniorrhaphy, Pain, Postoperative
Post-Operative Analgesic Effects of Local Wound Infiltration With Ketorolac After Inguinal Herniorrhaphy
Inguinal hernia is one of the most common diseases worldwide, including Thailand. Patients who underwent treatment of inguinal hernia (herniorrhaphy) found surgical site pain.There are many procedures to relieve pain after…
- Trial name
- NCT03534505
- Testing
- Ketorolac group, Bupivacaine group
- Where
- Thailand
- Volunteers
- 10 people
- Sponsor
- Mahidol University
Pain, Chest
Bilateral Pecto Intercostal Fascial Plane Block After Open Heart Surgeries
The objective is to test the effect of pecto intercostal fascial plane block (PIFB) as regard its impact on pain after sternotomy involved open heart surgery.
- Trial name
- PIFB (NCT04134637)
- Testing
- ultrasound, Bupivacaine Hydrochloride 5 MG/ML
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Fayoum University Hospital
Brain Edema, Craniocerebral Trauma
A Comparison Between Two Techniques for Performing Decompressive Craniectomy
The purpose of this study is to compare two surgical techniques for a neurosurgical procedure used to treat cerebral edema (decompressive craniectomy): with watertight duraplasty vs.
- Conditions
- Brain Edema, Craniocerebral Trauma, Infarction, Middle Cerebral Artery
- Trial name
- NCT02594137
- Testing
- Without watertight duraplasty
- Volunteers
- 58 people
- Sponsor
- Hospital of the Restoration, Recife
Spinal Cord Injuries
Self-Management Across the Care Continuum
Persons with spinal cord injury (SCI) face many challenges as they transition from inpatient care to outpatients and on into the community.
- Trial name
- NCT04540679
- Testing
- VIP4SCI
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Tinnitus
Telephone Tinnitus Education for Patients With Traumatic Brain Injury (TBI)
This study continues the investigators' efforts to develop tinnitus management protocols for Veterans. More specifically, this study developed and evaluated an adaptation of Progressive Tinnitus Management (PTM) for use as a…
- Trial name
- NCT01129141
- Testing
- Tele-PTM, Wait List Control
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- VA Office of Research and Development
Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE)
Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)
This international study, organized by Healing Hope International, is an observational registry designed to collect real-world data on participants living with chronic hypoxic ischemic encephalopathy (HIE) who receive an emerging…
- Conditions
- Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE), Hypoxic Ischaemic Encephalopathy Due to Cardiac Arrest, Hypoxic Ischemic Encephalopathy of Newborn
- Trial name
- GEN-HOPE (NCT07264166)
- Where
- Mexico
- Volunteers
- 25 people
- Sponsor
- Healing Hope International
Rotator Cuff Tears
The Impact of Cervical Radiculopathy on Functionality in Patients Undergoing Rotator Cuff Repair
The aim of the study is to evaluate the impact of cervical radiculopathy on functional status and quality of life outcomes in patients who have undergone rotator cuff repair, comparing the group with a history of cervical…
- Trial name
- NCT07001566
- Testing
- There was no intervention. Only assessment procedure will be performed.
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Biruni University
Disorder of Consciousness, Consciousness, Loss of
SeeMe: An Automated Tool to Detect Early Recovery After Brain Injury
Early prediction of outcomes after acute brain injury (ABI) remains a major unsolved problem. Presently, physicians make predictions using clinical examination, traditional scoring systems, and statistical models.
- Conditions
- Disorder of Consciousness, Consciousness, Loss of, Trauma, Brain, Traumatic Brain Injury
- Trial name
- NCT06083441
- Testing
- SeeMe, Coma Recovery Scale-Revised (CRS-R)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Stony Brook University