Clinical trials: Trauma, Spinal Cord
Spinal Cord Injuries
Reactive Stepping Training in Individuals With Spinal Cord Injury
Falling is common among individuals with incomplete spinal cord injury (iSCI), with most falls occurring while walking. Falls result in injuries (e.g., broken bones), hospital readmission, and reduced participation in work and…
- Trial name
- NCT02960178
- Testing
- Perturbation-based training, Conventional walking training
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University Health Network, Toronto
Spinal Cord Injury
Study on Functional Electrical Stimulation (FES) Cycling Following Spinal Cord Injury
This research is being done to study the effect of Functional Electrical Stimulation (FES) cycling on factors in blood and spinal cord in people with spinal cord injury (SCI).
- Trial name
- CURE-SCI (NCT01217047)
- Testing
- FES Cycling, Cycling without FES, Lumbar puncture
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Internet-Delivered Cognitive Behavioural Therapy, Depression
ICBT Program for Caregivers of Persons With SCI
Spinal cord injuries have a devastating effect on individuals incurring the life changing event; however, the injury can also affect those who are integrally involved in their care.
- Conditions
- Internet-Delivered Cognitive Behavioural Therapy, Depression, Anxiety, Spinal Cord Injuries
- Trial name
- NCT05346913
- Testing
- Internet-delivered Cognitive Behavioural Therapy(ICBT)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Neurogenic Bowel
Improving Bowel Function and Quality of Life After Spinal Cord Injury
Bowel dysfunction is consistently rated as one of the most common complications affecting daily life for individuals with spinal cord injury.
- Trial name
- NCT03949660
- Testing
- Stimulation for blood pressure without stand, Stimulation for blood pressure with stand, Stimulation for trunk and core without stand
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- University of Louisville
Spinal Cord Injuries (SCI)
High-intensity Walking Rehabilitation in Outpatient Subacute Spinal Cord Injury
People with incomplete spinal cord injury (SCI) often have some preserved movement and may regain walking ability, but recovery can be limited, and more effective rehabilitation approaches are needed.The goal of this clinical…
- Trial name
- NCT07553923
- Testing
- High-intensity Rehabilitation, Usual Care
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University of Alberta
Spinal Cord Injuries
A Novel Cooling Vest to Protect Persons With SCI From Hyperthermia
Persons with higher levels of spinal cord injury (above the 6th thoracic vertebrae: Hi-SCI) are unable to maintain their core body temperature (Tcore) within the normal range (97.5-99.7 °F) when exposed to warm environments.
- Trial name
- NCT05441449
- Testing
- Cooling Vest
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Neuropathic Back Pain, Spinal Cord Injury
Injecting Botulinum Toxin A Underneath the Skin to Treat Spinal Cord Pain in Patients With Spinal Cord Injury
Back pain is a common secondary condition of both acute and chronic spinal cord injury (SCI). Current existing treatment including both pharmacologic and non-pharmacologic are limited by marginal efficacy or intolerable side…
- Trial name
- NCT02736890
- Testing
- Botulinum Toxin A
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Multiple Sclerosis, Stroke
Lakeshore Examination of Activity and Disability Exercise Response Study
This study will examine the effectiveness of two types of group exercise classes on the health and functional status in inactive adults age 18-65 with neurological conditions including Multiple Sclerosis, stroke, and spinal cord…
- Trial name
- LEADERS (NCT02533882)
- Testing
- Movement to Music, Adapted Yoga
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Alabama at Birmingham
Spinal Cord Injuries
Evaluation of Sensory-motor Response to Low-level Laser Therapy for the Treatment of Spinal Injuries
Spinal cord injuries have become increasingly frequent due mainly to the increase in urban violence. The growing number of automobile collisions and violence-related events merits particular attention, as such occurrences can…
- Trial name
- NCT03031223
- Testing
- low-level laser therapy
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Nove de Julho
Pain Management
BreEStim in Managing Neuropathic Pain After Spinal Cord Injury (SCI)
The purpose of this study is to compare the effectiveness of innovative intervention of breathing controlled electrical stimulation (BreEStim) and sham BreEStim and Transcutaneous Electrical Nerve Stimulation (TENS) in management…
- Trial name
- NCT07659743
- Testing
- Active BreEStim Treatment, The TENS Treatment
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- The University of Texas Health Science Center, Houston
Spinal Cord Injuries, Spastic Gait
Neuromodulation of Ankle Muscles in Persons With SCI
The ability to voluntarily move the ankles is important for walking. After spinal cord injury (SCI), this ability is impaired because of changes in the communication between the brain, spinal cord, and body.
- Conditions
- Spinal Cord Injuries, Spastic Gait, Foot Drop
- Trial name
- NCT04238013
- Testing
- Whole Body Vibration (WBV), Electrical Stimulation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Shepherd Center, Atlanta GA
Spinal Cord Injury
High Frequency SARS for Neurogenic Bladder and Bowel Emptying
The purpose of this study is to determine if bladder emptying can be achieved using stimulation of the sacral roots at certain frequencies. Neurogenic bladder dysfunction occurs after spinal cord injury (SCI).
- Trial name
- SARS600 (NCT05214378)
- Testing
- Finetech-Brindley Sacral Anterior Roots Stimulation System
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- VA Office of Research and Development
Cervical Spinal Cord Injury, Cervical Cord Injuries Spinal
Low Volume Nose Resistance Breathing Exercise With Incentive Spirometer in Patient With Cervical Spinal Cord Injuries
This randomized clinical trial aims to evaluate the effectiveness of combining Low Volume Nose Resistance Breathing Exercises (LVNRBE) with Incentive Spirometry (IS) on respiratory outcomes in patients with cervical spinal cord…
- Trial name
- NCT07645027
- Testing
- Acapella device plus Incentive Spirometry, conventional respiratory physiotherapy
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Spinal Cord Injury
Exoskeletons for Spinal Cord Injury: A Feasibility Study
In this study, 10 volunteer participants with chronic spinal cord injury will undergo a 10-week training schedule for ambulation with the ReWalk™ device.
- Trial name
- NCT01943669
- Testing
- ReWalk™ device
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Buckinghamshire Healthcare NHS Trust
Spine Surgery, Excessive Repair
Use of Spinal Sealant System During Spinal Surgery
1. To evaluate the safety and efficacy of the Spinal Sealant as an adjunct to sutured dural repair compared with standard of care methods (control) to obtain watertight dural closure intraoperatively in patients undergoing spinal…
- Conditions
- Spine Surgery, Excessive Repair, Spinal Cord Injuries, Complication of Surgical Procedure
- Trial name
- NCT00458354
- Testing
- Spinal Sealant, Standard Methods of Closing of the Dura
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- M.D. Anderson Cancer Center
Spinal Cord Injuries, Paraplegia, Spinal
Activity-Dependent Transspinal Stimulation in SCI
Robotic gait training is often used with the aim to improve walking ability in individuals with Spinal Cord Injury. However, robotic gait training alone may not be sufficient.
- Conditions
- Spinal Cord Injuries, Paraplegia, Spinal, Tetraplegia/Tetraparesis, Paraplegia, Spastic
- Trial name
- NCT03669302
- Testing
- Robotic gait training, Robotic gait training and low-frequency transspinal stimulation, Robotic gait training and high-frequency transspinal stimulation
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- City University of New York
Neurogenic Bladder
Incidence of Urinary Tract Infection After Urodynamic Investigation
The purpose of this study is to evaluate the incidence of urinary tract infection after urodynamic investigation and to identify the involved germs.
- Trial name
- NCT01297647
- Testing
- urodynamic examination
- Where
- Switzerland
- Volunteers
- 317 people
- Sponsor
- Balgrist University Hospital
Spinal Cord Injury
Xo-Motion R Exoskeleton in SCI-Adoption Study
After spinal cord injury (SCI), many people lose their ability to walk and do not have access to equipment and assistance that could help them regain functional abilities.
- Trial name
- NCT07380516
- Testing
- XoMotionR- assisted locomotor training
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Alberta
Spinal Cord Injuries (SCI)
Myofascial Release and 20-m Speed in Wheelchair Rugby Athletes With Spinal Cord Injury
This study aims to investigate the effect of myofascial release on sprint performance in wheelchair rugby athletes with spinal cord injury.
- Trial name
- MFR20MWR (NCT07711015)
- Testing
- Myofascial Release
- Where
- Brazil
- Volunteers
- 12 people
- Sponsor
- Centro Universitário Augusto Motta
Sleep Apnea, Breathing Disorder During Sleeping
Sleep Apnea in Paralympic Ontario-Resident aThletes With Spinal Cord Injury (SPORTS) Study
This single arm clinical trial will assess whether continuous positive airway pressure (CPAP) therapy in the management of moderate-to-severe sleep-related breathing disorders (SRBDs) among para-athletes living with…
- Conditions
- Sleep Apnea, Breathing Disorder During Sleeping, Sleep Disorder, Spinal Cord Injuries
- Trial name
- NCT06195878
- Testing
- CPAP Therapy
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University Health Network, Toronto