Clinical trials: Trauma, completed
Lymphoma
Comparison Study of Doxorubicin Versus Epirubicin-induced Cardiotoxicity in Patients With DLBCL
The aim of this study is to compare CHOP versus CEOP-induced cardiotoxicity in patients with aggressive B-cell lymphoma. The hypothesis is epirubicin is associated with less cardiotoxicity without compromising the efficacy.
- Trial name
- NCT00854568
- Testing
- CEOP regimen, CHOP regimen
- Where
- China
- Volunteers
- 398 people
- Sponsor
- Fudan University
Trauma, Coagulopathy
Freeze-dried Plasma in the Initial Management of Coagulopathy in Trauma Patients
Knowledge and management of bleeding in severe trauma has changed. A specific coagulopathy is present in 40% of cases. It has a very early onset and this coagulopathy is associated with increased mortality.
- Trial name
- TrauCC (NCT02750150)
- Testing
- Freezed-dried plasma, Fresh-frozen plasma
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Lille
Achilles Tendinitis
A Pilot Study: Treatment of Achilles Tendinopathy With Platelet-Rich Plasma Therapy
The overall goal of this proposal is to correlate ultrasound elastography technique with more standard clinically based outcome measures within the setting of a small sample sized group of patients affected by moderate-to…
- Trial name
- NCT01911650
- Testing
- Autologous Platelet Rich Plasma, Ultrasound Imaging, Quality of Life Questionnaires
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Acute Kidney Injury
Identification of Preoperative Parameters to Predict Acute Kidney Injury Risk Following Vascular or Digestive Surgery
The study aims to identify the preoperative parameters associated with the risk of postoperative acute kidney injury (in particular the parameters of the SPARK score) in patients of the Besançon University Hospital who have…
- Trial name
- SCOPING (NCT05660174)
- Where
- France
- Volunteers
- 2,626 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Distal Radius Fractures, Lidocaine
Ultrasound-guided Infraclavicular Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures
To investigate the feasibility of the lateral infraclavicular plexus brachialis (LIC) block for acute closed reduction of distal radius fractures, the investigators will compare the pain-relieving and muscle-relaxing properties…
- Conditions
- Distal Radius Fractures, Lidocaine, Ropivacaine, Fracture Dislocation
- Trial name
- NCT06379490
- Testing
- Ropivacaine 0.2% Injectable Solution, Lidocaine epinephrine, Ropivacaine 0.5% Injectable Solution
- Where
- Denmark
- Volunteers
- 67 people
- Sponsor
- Nordsjaellands Hospital
Sexual Violence, Posttraumatic Stress Disorder
Testing STAR and TexSTAR: A Video and Text Messaging Intervention
This NIDA-funded HEAL Initiative: Opioid Use Disorder Care Pathways for Individuals with Histories of Exposure to Violence R61 seeks to develop and test a brief video intervention to deliver during Sexual Assault Nurse Examiner…
- Conditions
- Sexual Violence, Posttraumatic Stress Disorder, Opioid Use, Opioid Misuse
- Trial name
- NCT06456190
- Testing
- Skills Training in Active Recovery (STAR) Video, Text Skills Training in Active Recovery (TextSTAR) program
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Wisconsin, Madison
Degenerative Arthritis of Left Glenohumeral Joint, Degenerative Arthritis of Right Glenohumeral Joint
Costs and Consequences of Three Common Orthopedic Procedures on the Upper Extremity
This study compares costs and effectiveness / utility of three common orthopedic surgeries in shoulder and hand from the perspective of the Swiss health system and the clinic.
- Conditions
- Degenerative Arthritis of Left Glenohumeral Joint, Degenerative Arthritis of Right Glenohumeral Joint, Rotator Cuff Tear Arthropathy, Rotator Cuff Tear
- Trial name
- NCT01954433
- Testing
- Operated TSA Patients, Operated RCR Patients, Resection interposition suspension arthroplasty (RISA)
- Where
- Switzerland
- Volunteers
- 450 people
- Sponsor
- Schulthess Klinik
TBI (Traumatic Brain Injury)
Improving Functions in MTBI Patients With Headache by rTMS
Due to recent wars in Afghanistan and Iraq, the number of Veteran suffering from Mild traumatic brain(MTBI) injury and PTSD increases rapidly.
- Trial name
- NCT01948947
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- VA Office of Research and Development
Trauma, Anxiety
The Ukrainian Student Problem Solving Project
The purpose of this study is to test the effectiveness of a universal, digital, single-session intervention for youth mental health, functioning, and well-being.
- Conditions
- Trauma, Anxiety, Depression, Child Behavior
- Trial name
- NCT06064578
- Testing
- Project SOLVE
- Where
- United States
- Volunteers
- 778 people, healthy volunteers welcome
- Sponsor
- Harvard University
Osteopenic Women, Proximal Femur Fracture
Copley II: Long-term Outcome Follow-up Study of Osteoporotic Women Who Underwent a Local Osteo-Enhancement Procedure (LOEP) in the Proximal Femur
To evaluate longer-term (5-7 years) outcomes of the twelve (12) subjects treated with AGN1 Femoral LOEP in the clinical study "A Prospective Pilot Evaluation of Percutaneous Osteo-supplementation in the Proximal Femur of…
- Trial name
- NCT06799143
- Volunteers
- 12 people
- Sponsor
- AgNovos Healthcare, LLC
Spina Bifida, Cerebral Palsy
Assessing Transition Practices for Children With Disabilities: Pathways to a Successful Adulthood
Transition to adult care is a purposeful and structured movement of youth with complex disabilities from child centered to adult oriented services. This complex and potentially challenging period requires careful planning.
- Conditions
- Spina Bifida, Cerebral Palsy, Spinal Cord Injury, Spastic Paraplegia
- Trial name
- NCT07706517
- Testing
- Chart review, Semi-structured interview
- Where
- France
- Volunteers
- 128 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Pressure Injuries, Spinal Cord Injuries (SCI)
Electrical Stimulation for Clinical and Psychosocial Outcomes in Chronic Pressure Injuries
Pressure injuries are chronic wounds that frequently occur in immobilized patients and are associated with delayed healing, reduced quality of life, and significant psychological burden.
- Conditions
- Pressure Injuries, Spinal Cord Injuries (SCI), Traumatic Brain Injury
- Trial name
- NCT07493889
- Testing
- High-Voltage Monophasic Pulsed Current Electrical Stimulation, Standard Wound Care
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Spinal Cord Injury
Synchronous Tele-Resistance Training to Improve Upper Extremity Function in Patients With Spinal Cord Injury
This study investigated the effects of resistive exercises applied with synchronized telerehabilitation on upper extremity functions in patients with SCI who use wheelchairs.
- Trial name
- TELERES-SCI (NCT07115693)
- Testing
- Telerehabilitation-Based Resistance Exercise Program, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Hacer Önen Tekin
Rectal Cancer, Abdominoperineal Resection
APEMESH- Preventing Perineal Complications After Abdominoperineal Resection
Abdominoperineal resection leaves an empty space to be filled by mesh or musculocutaneus flap. Several studies have reported over 30% morbidity with perineal wound healing after abdominoperineal resection.
- Conditions
- Rectal Cancer, Abdominoperineal Resection, Wound Heal
- Trial name
- NCT04334421
- Testing
- Composite mesh
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Elisa Mäkäräinen
Surgical Wound
AMBULATE Continued Access Protocol to Evaluate the Cardiva Mid-Bore Venous Vascular Closure System (VVCS)
The objective of the trial is to demonstrate the safety and effectiveness of the Cardiva Mid-Bore Venous Vascular Closure System (VVCS) in sealing femoral venous access sites at the completion of catheter-based procedures…
- Trial name
- NCT03573206
- Testing
- Cardiva Mid-Bore Venous Vascular Closure Device (VVCS)
- Where
- 3 sites in United States
- Volunteers
- 168 people
- Sponsor
- Cardiva Medical, Inc.
Orthopedic Disorder, Nontraumatic Injury
Web-based Mind-body Program for Comorbid Nontraumatic Upper-extremity Condition and Risky Substance Use
The investigator aims to conduct an open pilot study (N=6; 5 completers) to test the feasibility, acceptability, and credibility of an asynchronous web-based mind-body intervention (Toolkit for Resilient Life beyond Pain and…
- Conditions
- Orthopedic Disorder, Nontraumatic Injury, Substance Use, Upper Extremity Problem
- Trial name
- NCT06366633
- Testing
- Web-TIRELESS
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Jafar Bakhshaie
Spinal Cord Injury
FES Rowing for Skeletal Health After SCI
Following a complete spinal cord injury (SCI), individuals experience progressive bone loss, especially in the legs, with up to 70% of persons with SCI sustaining a fracture at some point during their lifetime.
- Trial name
- FES-R (NCT02008149)
- Testing
- Rowing exercise
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- VA Office of Research and Development
Shoulder Injuries
Effect of Thrower's Ten Exercise Program on Shoulder Flexibility, Stability and Strength in Water Polo Players
Context: Studies have shown that the thrower's ten rehabilitation program is effective in the prevention and rehabilitation of injuries in overhead throwing sports. However its effect on water polo sports is still unknown.
- Trial name
- NCT05945238
- Testing
- Thrower's Ten Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Baskent University
Transradial Catheterization
Differences in Radial Artery Occlusion From Two Different Compressive Methods Used in Patients in Order to Achieve Homeostasis After Transradial Catheterization and Their Repercussion in Artery Functionality and Hand Mobility
The aim of the study is to determine differences on radial artery occlusion from two compressive methods used after transradial catheterization and its functional impact on hand mobility.
- Trial name
- NCT02697526
- Testing
- Terumo, Tensoplast
- Where
- Spain
- Volunteers
- 274 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
To Explore the Influence of CRRT Nursing Team Management Plan on the Prognosis of SAKI Patients
Impact of the CRRT Management Protocol on Prognostic Outcome in Patients With Septic Acute Kidney Injury
The implementation of CRRT nursing team management program in the treatment of SAKI can significantly reduce the incidence of adverse events and complications in CRRT nursing, which has a positive role in improving the success…
- Trial name
- NCT06083285
- Testing
- Implement the CRRT specialist nursing group management program on the basis of routine care
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Xinjiang Medical University