Clinical trials: Trauma Abdomen
Open Wound Abdominal Wall, Wound Non Healing
Effect of Oasis® Wound Matrix on Stage III and IV Trunk Pressure Wounds Treated With Negative Pressure Wound Therapy
This study evaluates the therapeutic effect of Oasis® Matrix along with Negative Pressure Wound Therapy (NPWT) on pressure wounds. Either Oasis or standard foam will be applied to the wound prior to activating the NPWT.
- Trial name
- NCT02246608
- Testing
- NPWT Standard of Care plus Oasis wound product, Routine NPWT Standard of Care
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Kettering Health Network
Appendicitis
European Society for Trauma and Emergency Surgery (ESTES) Cohort Study Snapshot Audit 2020 - Acute Appendicitis
Background Acute appendicitis is an extremely common surgical emergency. Traditionally, appendicitis has been managed surgically.
- Trial name
- SnapAppy (NCT04365491)
- Where
- Ireland
- Volunteers
- 4,000 people
- Sponsor
- Gary Alan Bass, MD PhD
Appendicitis, Surgical Site Infection
Transumbilical Laparoscopic Appendectomy
Transumbilical laparoscopic appendectomy (TULA) is increasingly favored in the treatment of appendicitis within the realm of minimally invasive surgical approaches.
- Trial name
- NCT06177418
- Testing
- Transumbilical laparoscopic appendectomy + Glove finger technique, Standard transumbilical laparoscopic appendectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Necmi Kadıoğlu Hospital
Endometrial Adenocarcinoma
Effects of Wound Infiltration With Ketamine Versus Dexmedetomidine Added to Bupivacaine on Cytokines
This study aims to compare the effects of local wound infiltration with ketamine versus dexmedetomidine when added to bupivacaine on inflammatory cytokine response after total abdominal hysterectomy.
- Trial name
- NCT03164590
- Testing
- Ketamine, dexmedetomidine, bupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Acute Kidney Injury
Correlation Between Preoperative NT-proBNP and Postoperative AKI
Accurate preoperative AKI risk prediction is of great significance for improving patient outcomes. The use of preoperative NT-proBNP can provide a more precise assessment of the body's fluid load status, guide intraoperative and…
- Trial name
- NCT06145347
- Where
- China
- Volunteers
- 629 people
- Sponsor
- Xijing Hospital
Analgesia, Thoracic Tumors
Real-time Ultrasound Guidance for Thoracic Epidural Blocks
Various modalities have been proposed for real-time confirmation of loss of resistance (LOR) for thoracic epidural blocks. With real-time ultrasound (US) guidance, the anesthesiologist attempts to visualize the sonographic…
- Conditions
- Analgesia, Thoracic Tumors, Abdomen Tumors, Rib Fractures
- Trial name
- NCT05165498
- Testing
- Real-time ultrasound guidance for thoracic epidural catheter placement.
- Where
- Chile
- Sponsor
- University of Chile
Surgical Procedure
Impact of Marking Surgical Incision on Patient's Abdomen
This is a study looking at patient's satisfaction with incision site and location after undergoing minimally invasive gynecologic surgery.
- Trial name
- NCT01803334
- Testing
- Marking abdomen
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- AdventHealth
Core Strength, Knee Stability
Influence of Abdominal Muscle Function on Knee Stability for Injury Prevention
The goal of this clinical trial is to learn whether an 8-week core stabilization training program can improve abdominal strength and knee stability in physically active women aged 18 to 35.
- Trial name
- NCT07499973
- Testing
- Core Stabilization Training Program
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- European University of Madrid
Stress Reaction
Relationship Between Lidocaine and Serum Orphanin FQ (N/OFQ)
The intravenous injection of lidocaine during the perioperative period has been widely used in various types of surgeries. Its clinical effect includes reducing stress response during anesthesia, decreasing pain and opioid…
- Trial name
- NCT05899127
- Testing
- Lidocaine, 0.9%NaCl
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Hospital of Shanxi Medical University
Trauma Injury, Major Abdominal Surgery
Bolus Versus Continuous Enteral Tube Feeding
Stress metabolisms induced by severe trauma, large abdominal surgery procedures, sepsis, etc. leads to metabolic changes, which increase energy expenditure, enhanced protein catabolism, insulin resistance.
- Conditions
- Trauma Injury, Major Abdominal Surgery, Sepsis
- Trial name
- NCT04080479
- Testing
- Quadriceps Muscle Layer Fitness, Muscle Strength, Acute Physiology and Chronic Health Evaluation
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- University Hospital Ostrava
Abdominal Hysterectomy, Postoperative Pain
Effect of TAP Block on Stress Hormones
Random allocation of patients in two groups; Tap block group (T group) and control group (C group). All patients will receive standard general anesthesia and postoperative pain management.
- Trial name
- NCT03443271
- Testing
- TAP Block with Bupivicaine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Hernia, Inguinal
M-Tapa Block for Laparoscopic Inguinal Hernia Repair Surgery
Modified Perichondral Approach Thoracoabdominal Nerve (M-TAPA) block is a novel block that provides effective analgesia of the anterior and lateral thoracoabdominal walls during laparoscopic surgery, in which local anesthetic is…
- Trial name
- NCT05199922
- Testing
- M TAPA block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Incisional Hernia, Abdominal Hernia
Hernia Sac Flap Coverage of Mesh in Bony-Edged Ventral Hernia Repair
This trial asks whether covering the inner, bowel-facing surface of a hernia mesh with a flap of the patient's own hernia sac improves healing after repair of a complex ventral (abdominal wall) hernia in which one edge of the…
- Conditions
- Incisional Hernia, Abdominal Hernia, Complex Ventral Hernia, Surgical Site Infection
- Trial name
- PERI-SAC (NCT07720154)
- Testing
- Sac-flap peritonealization of the mesh, Retromuscular (sublay) synthetic mesh repair
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Minia University
Pain
Transverses Abdominis Plane Block Versus Local Wound Infiltration in Total Abdominal Hysterectomy
To compare the transverses abdominis plane block outcome versus local wound infiltration for postoperative analgesia in patients undergoing total abdominal hysterectomy.
- Trial name
- NCT06256302
- Testing
- Transverses Abdominis Plane Block, Local wound infiltration
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Dr Muhammad Arif
MINS
PeriOperative Medicine - Metabolic Inflexibility as a Mechanism for Myocardial Injury After Non-Cardiac Surgery
The goal of this observational study is to learn whether metabolic inflexibility, which means reduced ability of the body to switch between using fats and sugars for energy, is associated with myocardial injury after non-cardiac…
- Trial name
- POM-MIMICS (NCT07694453)
- Testing
- Pre-operative Metabolic Inflexibility
- Volunteers
- 300 people
- Sponsor
- University College, London
Acute Appendicitis, Perforated Gastroduodenal Ulcer
Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures
Aim of prospective randomized a placebo controlled study is to prove that in case of acute surgical procedure due to appendicitis, ileus of small bowel and perforation of small bowel and stomach appropriately administered…
- Conditions
- Acute Appendicitis, Perforated Gastroduodenal Ulcer, Small Bowel Obstruction
- Trial name
- NCT01524081
- Testing
- Metronidazole, Cefuroxime, Amoxicillin (+ clavulanic acid) and Fluconazole
- Where
- Czechia
- Volunteers
- 187 people
- Sponsor
- The Faculty Hospital Na Bulovce
Incisional Hernia, Surgical Site Infection
Prophylactic Mesh Reinforcement for Stoma Closure
In the current work we are aiming to compare between the mesh-reinforced stoma closure and the anatomical closure in terms of the risk of developing surgical site incisional hernia (SSIH),incidence of surgical site infection …
- Conditions
- Incisional Hernia, Surgical Site Infection, Postoperative Pain, Hospital Stay, Length of Stay in Hospital From Surgery to Discharge
- Trial name
- OASIS (NCT06157645)
- Testing
- Prolene mesh
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Assiut University
Gastric Cancer, Surgical Wound Infection
Fatigue and QoL Among Gastric Cancer Patients Undergoing Abdominal Surgery
Background: Cancer-related fatigue (CRF), one of the indicators of QoL, is one of the most common side effects of cancer and its treatment.
- Conditions
- Gastric Cancer, Surgical Wound Infection, Fatigue, Quality of Life
- Trial name
- NCT03766945
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Trauma Abdomen
CEUS for Blunt Abdominal Trauma in Children
Children with blunt abdominal trauma often get a CT as the first line imaging to evaluate for intra-abdominal organ injury. CT scans have some downsides with regard to radiation exposure, costs, and need for transport.
- Trial name
- NCT03490929
- Testing
- Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Intravenous Powder for Suspension [LUMASON], contrast-enhanced ultrasound
- Where
- 2 sites in United States
- Volunteers
- 146 people
- Sponsor
- Children's Hospital of Philadelphia
Hernia Incisional, Suture, Complication
DuraMesh Laparotomy Closure Following Trauma and Emergency Surgery
The proposed project aims to evaluate the safety of DuraMesh™ suture for laparotomy closure in an emergent setting, while also providing preliminary efficacy data with regard to incisional hernia prevention.
- Trial name
- NCT04312165
- Testing
- Duramesh Laparotomy Closure, Conventional suture closure
- Where
- 2 sites in United States
- Sponsor
- Uniformed Services University of the Health Sciences