Clinical trials: Trauma ICU Patients, open to volunteers
Trauma Injury
Retrospective Assessment of Referral of a Major Trauma Patient
The aim of this study is to find out whether major trauma patients from the Val d'Oise are referred to the appropriate trauma centre for their care and to assess the quality of triage within the Val d'Oise department.
- Trial name
- SAMU-TRAUMAS (NCT06551350)
- Testing
- Data Collection
- Where
- France
- Volunteers
- 461 people
- Sponsor
- Hôpital NOVO
Communication Barriers
Understanding Communication Barriers in Acute Care: A Mixed-Methods Needs Assessment Among Healthcare Providers Caring for Non-Verbal Patients With Spinal Cord Injury and Tracheostomy in the ICU
Communication impairment is common among critically ill patients who are mechanically ventilated, have tracheostomies, or have neurological injuries such as spinal cord injury.
- Trial name
- NCT07796035
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Subarachnoid Hemorrhage, Aneurysmal, Brain Injuries, Traumatic
Prospective Observational Multimodal Neuromonitoring in Adult NSICU Patients
This is a prospective observational cohort study of adult patients admitted to the Neurosciences Intensive Care Unit (NSICU) at UT Southwestern Medical Center.
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Brain Injuries, Traumatic, Cerebral Hemorrhage, Ischemic Stroke
- Trial name
- NCT07577713
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Texas Southwestern Medical Center
Platelets/Albumin and Aki
Platelets to Albumin Ratio for Prediction of Acute Kidney Injury in Patients Admitted to the Intensive Care Unit
To evaluate the role of platelet to albumin ratio to detect Acute kidney injury in patients admitted to intensive care
- Trial name
- NCT06554977
- Testing
- Laboratory
- Volunteers
- 140 people
- Sponsor
- Assiut University
Post Intensive Care Syndrome (PICS), PTSD - Post Traumatic Stress Disorder
ICU-VR Prior to ICU Admission
Rationale: A substantial proportion of the Intensive Care Unit (ICU) survivors develop psychological impairments due to their ICU admission.
- Trial name
- NCT06642636
- Testing
- Intensive Care Unit-specific Virtual Reality
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Denzel Drop
Pressure Injury, Intensive Care Unit (ICU)
Arterial Blood Gas Levels, Oxygen Saturation, and Pressure Injury Risk in ICU Patients
The purpose of this study is to examine the relationship between arterial blood gas (ABG) parameters and oxygen saturation (SpO₂) levels and the risk of pressure injury development in patients hospitalized in intensive care…
- Trial name
- NCT07691710
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Istanbul University
Traumatic Brain Injury (TBI) Patients
Efficacy of Propranolol in Traumatic Brain Injury Patients Admitted to the ICU: A Prospective, Randomized, Triple-Blind Study
Beta-blockers have shown promise as a treatment to improve patient prognosis following traumatic brain injury (TBI), although the exact mechanism by which they might confer this benefit remains unknown.
- Trial name
- ProP-TBI ICU (NCT07899164)
- Where
- 6 sites in Spain
- Volunteers
- 536 people
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Traumatic Brain Injury (TBI) Patients, Intracerebral Hemorrhage
Smartphone Enabled Detection of Cognitive Motor Dissociation in the ICU
The purpose of this research study is to evaluate whether a smartphone-enabled EEG (electroencephalography) system can be used to detect Cognitive Motor Dissociation (CMD) in patients with acute neurological injuries who appear…
- Conditions
- Traumatic Brain Injury (TBI) Patients, Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Cardiac Arrest (CA)
- Trial name
- SMART-CMD (NCT07917728)
- Where
- 9 sites in United States, Brazil and 3 more
- Volunteers
- 240 people
- Sponsor
- Columbia University
Trauma (Including Fractures), Trauma ICU Patients
Mortality of Trauma in the Intensive Care Unit.
In this study, it was planned to establish the factors associated with severe trauma discharged from the intensive care unit and mortality.
- Conditions
- Trauma (Including Fractures), Trauma ICU Patients, Trauma Injury, Trauma Patients in ICU
- Trial name
- MOTRAM-ICU-COL (NCT07208110)
- Testing
- Exposed to trauma, Not exposed
- Where
- Colombia
- Volunteers
- 500 people
- Sponsor
- Hospital Departamental de Villavicencio
Polytrauma, Resuscitation, Trauma Patients
Pv-aCO₂ Gap-Guided Resuscitation in Adult Polytrauma Patients: A Prospective Randomized Controlled Trial
dult patients with multiple traumatic injuries admitted to the ICU from the operating room, emergency department, or hospital wards who meet the study criteria will be included after obtaining informed consent from the patient or…
- Trial name
- NCT07480655
- Testing
- Veno-arterial Carbondioxide gap, Conventional resuscitation end points
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Pakistan Institute of Medical Sciences
Transfusion-Related Acute Lung Injury, ARDS, Human
Comparison of the Proteome in ICU Patients in Search for TRALI Biomarkers: A Case-control Study Using Both Retrospective and Prospective Samples
Transfusion-related acute lung injury (TRALI) is a severe complication of blood transfusions. After a transfusion, TRALI develops in 0.08-15% of cases depending on the characteristics of the studied population.
- Trial name
- CURIE (NCT06444750)
- Testing
- Blood sample collection
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pressure Injury
Effectiveness of a Combined Aloe Vera-Peppermint Gel on Prevention Pressure Injuries Among Intensive Care Unit Patients
The goal of this clinical trails is to learn if a combined Aloe Vera-Peppermint gel work to prevent pressure injuries (bedsores) in ICU patients.
- Trial name
- APG-PI (NCT07537101)
- Testing
- combined Aloe Vera-Peppermint gel
- Where
- Iraq
- Volunteers
- 40 people
- Sponsor
- Ali Abd-Alredha Hussein
Acute Kidney Injury, Fluid Overload
Early Deresuscitation Strategy Driven by Tissue Perfusion in Renal Replacement Therapy in Patients With Acute Renal Failure
In Intensive Care Unit (ICU) patients with acute kidney injury (AKI) and treated with renal replacement therapy (RRT) often present a fluid overload which is associated with morbidity (mechanical ventilation duration increase…
- Trial name
- EarlyDry (NCT05817539)
- Testing
- Fluid balance negativation, Body weight Stabilization
- Where
- 14 sites in France
- Volunteers
- 250 people
- Sponsor
- Hospices Civils de Lyon
Polytrauma
Comparing Exponential Injury Severity Score (EISS) With Injury Severity Score (ISS) and New Injury Severity Score (NISS)
Trauma is defined as a physical injury from an external source of sudden onset and severity, which require immediate medical attention.
- Trial name
- NCT06653816
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Assiut University
Acute Respiratory Distress Syndrome (ARDS), Extracorporeal Membrane Oxygenation
Personalized Ventilator Settings for Patients on ECMO
While mechanical ventilation can be used to sustain life in those with lung injury, it, can further worsen lung injury or prevent lung healing resulting in high morbidity and mortality as seen in Acute Respiratory Distress…
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Extracorporeal Membrane Oxygenation, Respiratory Failure Patients Treated With ECMO, Respiratory Failure, ICU
- Trial name
- PEEPECMO (NCT07673250)
- Testing
- Personalized Positive End-Expiratory Pressure (PEEP)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of California, San Diego
Acute Kidney Injury, ICU Patients
Validation of a Regional Citrate Anticoagulation Protocol in Critically Ill Patients on Continuous Renal Replacement Therapy
The objective of this study is to evaluate the effectiveness of a modified continuous renal replacement therapy (CRRT) protocol in maintaining electrolyte balance in adult patients with acute kidney injury (AKI) admitted to the…
- Conditions
- Acute Kidney Injury, ICU Patients, Continuous Renal Replacement Therapy (CRRT), Electrolytes
- Trial name
- CRRT (NCT07514650)
- Testing
- continuous renal replacement therapy
- Where
- Spain
- Volunteers
- 43 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Acute Kidney Injury, Intra-Abdominal Hypertension
Cumulative Intra-Abdominal Pressure Burden and Acute Kidney Injury After Emergency Abdominal Surgery
The goal of this observational study is to learn whether increased pressure inside the abdomen over time is associated with acute kidney injury in adults receiving intensive care after emergency abdominal surgery.
- Trial name
- IAP-AKI (NCT07891026)
- Testing
- Serial Intra-Abdominal Pressure Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Ugur Duman
Acute Kidney Injury
Renal Angina Index for Predicting Acute Kidney Injury in Adult ICU Patients
Acute kidney injury (AKI) is a frequent complication of critical illness and is associated with increased morbidity and mortality.
- Trial name
- NCT07863505
- Testing
- Renal Angina Index Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 324 people
- Sponsor
- Izmir Katip Celebi University
Respiratory Insufficiency, Wounds and Injuries
Humidification Effects on Airway Complications and Clinical Outcomes in Trauma ICU Patients on Mechanical Ventilation
This study compares the effects of two primary airway humidification methods-active heated humidifiers (HHs) and passive heat-and-moisture exchangers (HMEs)-on trauma intensive care unit (ICU) patients requiring prolonged…
- Conditions
- Respiratory Insufficiency, Wounds and Injuries, Critical Illness
- Trial name
- NCT07713238
- Testing
- Airway Humidification Device
- Where
- Egypt
- Volunteers
- 162 people
- Sponsor
- Assiut University
Mechanical Ventilation Complication, Ventilator-Induced Lung Injury
A New Ultrasonographic Tool to Assess Pulmonary Strain in the ICU
The primary objective of the study is to create a small dataset of regional pulmonary strain values in patients suffering from pulmonary diseases under mechanical ventilation in an intensive care setting.
- Trial name
- NCT03405779
- Testing
- Lung ultrasonography
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)