Clinical trials: Trauma Nervous System
Psychotic Disorders, Mood Disorders
Transcranial Direct Current Stimulation as Treatment for Auditory Hallucinations
The present study aims to examine the efficacy of transcranial direct current stimulation on the severity of auditory hallucinations.
- Conditions
- Psychotic Disorders, Mood Disorders, Personality Disorders, Stress Disorders, Post-Traumatic
- Trial name
- tDCS (NCT01977521)
- Testing
- Eldith DC Stimulator stimulation
- Where
- Netherlands
- Volunteers
- 62 people
- Sponsor
- Iris Sommer
Shoulder Pain, Shoulder Impingement Syndrome
Corticosteroid Injection Versus Tendon Dry Needling for Subacromial Impingement Syndrome
This randomized clinical trial aims to compare the efficacy of corticosteroid injection and tendon dry needling for the treatment of subacromial impingement syndrome.
- Conditions
- Shoulder Pain, Shoulder Impingement Syndrome, Shoulder Impingement, Subacromial Impingement Syndrome
- Trial name
- NCT05882786
- Testing
- Corticosteroid injection, Dry Needling
- Volunteers
- 60 people
- Sponsor
- Uskudar State Hospital
Brain Injuries
Behavioral Trial Studying Programmed Training to Improve Advocacy Skills for Individuals With Traumatic Brain Injury
The Midwest Advocacy Project (MAP) is a community-based multiple-site randomized practical behavioral trial of advocacy skill training for individuals with traumatic brain injury (TBI), their families, and significant others.
- Trial name
- MAP (NCT01002677)
- Testing
- Advocacy training curriculum, Self-directed
- Where
- 3 sites in United States
- Volunteers
- 234 people
- Sponsor
- Mayo Clinic
TBI (Traumatic Brain Injury)
Evaluation of Military Service and Family Members for Post Concussive and Posttraumatic Stress Symptoms
This protocol is designed to facilitate the recruitment, screening and registry of Military Service Members (SMs) and individuals eligible for care in the Department of Defense (DoD) healthcare system.
- Trial name
- MRP (NCT03191357)
- Testing
- n/a observational
- Where
- United States
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Tibial Fractures, Leg Injuries
Light Therapy in the Treatment of Leg Pain
The purpose of this study is to apply Anodyne therapy to active duty soldiers, who have shin splints, to evaluate healing time and effectiveness.
- Trial name
- MilCAM (NCT00253981)
- Testing
- Monochromatic Near-Infrared Light Energy (MIRE)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Samueli Institute for Information Biology
Sleep Initiation and Maintenance Disorders, Stress Disorders, Posttraumatic
Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress
Post-traumatic stress disorder (PTSD) is a common consequence of combat that can result in trauma-related hyperarousal and sleep disturbances.
- Trial name
- NCT03642028
- Testing
- Suvorexant
- Where
- 4 sites in United States
- Volunteers
- 190 people
- Sponsor
- VA Office of Research and Development
Chronic Pain, Trauma
Influence of Trauma on Pain Area and Widespreadness in Chronic Pain Patients
It is well known that patients suffering from chronic pain report higher levels of pain, anxiety, and depression if they have experienced a traumatic event. However, little is know about pain area and widespreadness.
- Trial name
- NCT05190367
- Where
- Germany
- Volunteers
- 914 people
- Sponsor
- Hannover Medical School
Concussion, Mild, Concussion; Eye
EYE-SYNC Concussion Classification Study
The purpose of this study is to determine the sensitivity and specificity of an aid in assessment of concussion based on eye-tracking, in comparison to a clinical reference standard appropriate for sport-related concussion…
- Conditions
- Concussion, Mild, Concussion; Eye, Concussion, Brain, Concussion, Severe
- Trial name
- NCT04381767
- Testing
- EYE-SYNC
- Where
- United States
- Volunteers
- 1,303 people
- Sponsor
- Sync-Think, Inc.
Pain, Perioperative/Postoperative Complications
Wound Dressings For Split-Thickness Skin Graft Donor Sites in Patients Undergoing Surgery
This study is to determine what dressing would work best to heal and keep from hurting, the split-thickness skin graft donor site which will be done as part of the patient's surgical procedure.
- Trial name
- NCT01680367
- Testing
- wound care management, questionnaire administration
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Pain, Inflammatory Response
Association Between Body Composition and Pain in Spinal Cord Injury
The purposes of the study are to quantify and compare relationships among acute changes in inflammatory markers and evoked pain sensitivity after a high-fat meal (HFM) challenge, compared to a moderate-fat meal challenge, and…
- Trial name
- NCT05459207
- Testing
- Moderate Fat Meal, High Fat Meal
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Miami
Mild Traumatic Brain Injury, Concussion, Post Concussive Syndrome, Chronic
Effect of Mental Imagery in Patients With Persistent Post-concussion Symptoms
Background: Mild Traumatic Brain Injury (mTBI) often results in persistent emotional, cognitive, and somatic symptoms-such as headaches and dizziness.
- Conditions
- Mild Traumatic Brain Injury, Concussion, Post Concussive Syndrome, Chronic, Post Traumatic Headache
- Trial name
- NCT07166536
- Testing
- Provocation Test for Symptoms Using Mental Imagery
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Reuth Rehabilitation Hospital
Autonomic Dysreflexia, Spinal Cord Injuries
Prevention of Complications Due to Autonomic Dysreflexia in SCI Individuals
Autonomic dysreflexia (AD) is a syndrome of unbalanced response of the sympathetic system to noxious stimuli below the level of spinal cord injury (SCI), characterized by paroxysmal hypertension.
- Trial name
- NCT05024487
- Testing
- Clinical Examination
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Assoc. Prof. Jiri Kriz, MD, PhD
Brain Injury
Genotype Influence on Recovery After Traumatic Brain Injury
Genetic differences in response to brain injury may reasonably be expected to play a role in the initial consequences of traumatic brain injury and in the rate of recovery from such injury.
- Trial name
- NCT00018499
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Spinal Cord Injury
Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation: Effect on Imaging and Serum Biomarkers of Skeletal Muscle Mass and Bone Strength.
Immobilization following spinal cord injury (SCI) results in muscle and bone loss below the level of injury, which ultimately predisposes to fracture at several sites throughout the legs and can lead to several medical…
- Trial name
- NCT07418398
- Testing
- Exoskeleton-Assisted Walking (EAW), Active Transcutaneous Spinal Cord Stimulation (tSCS)
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- VA Office of Research and Development
Traumatic Brain Injury
A Health & Wellness Intervention for Individuals With Traumatic Brain Injury (TBI)
The primary goal of the proposed study is to evaluate the efficacy of a replicable community-based group intervention, designed to address both general wellness and specific TBI health-related issues.
- Trial name
- NCT01334398
- Testing
- Health & Wellness
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- VA Eastern Colorado Health Care System
Chronic Subdural Hematomas
PHIL™ Middle Meningeal Artery Embolization for First-Line Treatment of Chronic Subdural Hematoma IDE Trial
This is a prospective, randomized, controlled, open-label, blinded endpoint (PROBE) clinical investigation in which patients with non-emergent chronic subdural hematoma (cSDH) requiring treatment will be randomized (1:1) to…
- Trial name
- PHILFIRST (NCT07576998)
- Testing
- PHIL™ (Precipitating Hydrophobic Injectable Liquid), Surgical evacuation
- Volunteers
- 475 people
- Sponsor
- Microvention-Terumo, Inc.
Spinal Cord Injuries
Investigation of Brain Functional MRI as an Early Biomarker of Recovery in Individuals With Spinal Cord Injury
Early detection of response to therapeutic intervention is vital, as it will enable early termination of intervention in non-responding patients, prevent unnecessary financial burden, and allow for early changes to the…
- Trial name
- NCT03854214
- Testing
- Functional Electric Stimulation cycling, Passive cycling
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Head and Neck Cancer Survivors, Cancer of the Head and Neck Surviors
Head and Neck Cancer Survivorship Ototoxicity Screening (SOS)
To evaluate the effectiveness, feasibility, acceptability, and appropriateness of an ototoxicity screening protocol among head and neck (H\&N) cancer patients followed in survivorship clinic that received cisplatin-based…
- Trial name
- NCT05789316
- Testing
- Ototoxicity Screening Protocol
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Washington University School of Medicine
Carpal Tunnel Syndrome
Comparison of Efficacy Between Conservative Versus Operative Management of Carpel Tunnel Syndrome
Patients presented with symptoms of numbness at night, pain, or tingling sensation in the fingers particularly at night diagnosed by consultant orthopedic surgeon on physical examination.
- Trial name
- NCT06060314
- Testing
- Conservative Approach, Surgical Approach
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Combined Military Hospital Abbottabad
Spinal Cord Injury
Cardiovascular Autonomic Function After Resistance Training
The purpose of this clinical trial is to evaluate whether an 8-week upper-limb resistance training program improves cardiovascular autonomic function in adults with chronic spinal cord injury (SCI).
- Trial name
- NCT07725952
- Testing
- Upper-Limb Resistance Training
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Pusan National University Yangsan Hospital