Clinical trials: Trauma Prevention
Pressure Ulcers (Hospital-acquired Pressure Injuries)
Sacrum Pressure Injury Prevention Study Using ALLEVYN◊ Complete Care in Adults at Risk of Developing Hospital-acquired Pressure Injuries in Critical Care Units
The purpose of this study is to investigate the use of ALLEVYN◊ COMPLETE CARE Sacrum dressing for the prevention of hospital-acquired pressure injuries in adults.
- Trial name
- PACCT (NCT07849387)
- Testing
- ALLEVYN◊ COMPLETE CARE Sacrum
- Where
- 3 sites in United States
- Volunteers
- 330 people
- Sponsor
- Smith & Nephew, Inc.
Acute Respiratory Distress Syndrome, Covid19
Prevention of Acute Myocardial Injury by Trimetazidine in Patients Hospitalized for COVID-19
Acute myocardial injury has been a finding of variable frequency among patients diagnosed with COVID-19. It is now recognized that cTnI levels are strongly associated with increased mortality.
- Conditions
- Acute Respiratory Distress Syndrome, Covid19, Myocardial Injury
- Trial name
- PREMIER (NCT04760821)
- Testing
- Trimetazidine
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Ministry of Health, Brazil
Chronic Renal Insufficiency, Serum Creatinine Concentration
MESNA for Prevention of Acute Deterioration of Renal Function Following Contrast Agent Application
The purpose of this study is to determine wether Mesna could prevent contrast-induced nephropathy
- Conditions
- Chronic Renal Insufficiency, Serum Creatinine Concentration, Contrast Media Exposition
- Trial name
- NCT00223548
- Testing
- sodium 2-mercaptoethane sulfonate
- Where
- Germany
- Volunteers
- 106 people
- Sponsor
- University of Ulm
Cisplatin Ototoxicity
Prevention of Cisplatin-Induced Hearing Loss by Intratympanic Dexamethasone Treatment
Cisplatin is a widely used chemotherapeutic agent for the treatment of various malignant neoplasms, including testicular, ovarian, bladder, cervix uteri, head and neck and lung cancers.
- Trial name
- NCT01372904
- Testing
- Dexamethasone Phosphate
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Meir Medical Center
Sunburn, Ultraviolet Radiation Exposure
Test of Interventions to Prevent Skin Cancer Among Danes on Vacation in High UV Index Sunny Destinations
The aim of the study is to test a series of developed effective interventions targeting Danes going on vacation to sunny destinations to decrease sunburn by increasing use of shade, hats, protective clothing, and sunscreen to…
- Conditions
- Sunburn, Ultraviolet Radiation Exposure, Skin Cancer, Malignant Melanoma
- Trial name
- NCT03607578
- Testing
- Other: Control Group - Minimal Intervention, Experimental: Protection Routine 1, Experimental: Protection Routine 2
- Where
- Denmark
- Volunteers
- 1,548 people, healthy volunteers welcome
- Sponsor
- Brian Køster
Athletic Injuries, Shoulder Pain
Effects of a Therapeutic Exercise Program for Injuries Prevention in Wheelchair Basketball (WB) Players
Shoulder pain is the most common symptom of physical dysfunction in wheelchair basketball players. About the 85% of this population had shoulder pain in some moment of their life.
- Conditions
- Athletic Injuries, Shoulder Pain, Shoulder Injury
- Trial name
- NCT02842008
- Testing
- Exercise group
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universidad Politecnica de Madrid
Sport Injury
Effects of Different Exercise Programs on Injury Risk and Sports Performance in Adolescent Basketball Players
Basketball is a team sport where aerobic and anaerobic performance is important. Knowing how to reduce common injuries and risk is important when designing a warm-up exercise program for basketball.
- Trial name
- NCT05184543
- Testing
- Routine Exercise Program, Core Stability Exercise Program, Body Weight Neuromuscular Warm-Up Program
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Focus of Study: Bicycle Helmet Wearing Compliance
Prevention of Traumatic Brain Injury in Youth and Adolescents
The hypothesis was that the implementation of a Safe Kids East Central brain injury prevention program targeting children and caregivers admitted to the Georgia Health Sciences University Children's Medical Center is feasible and…
- Trial name
- NCT01629121
- Testing
- education intervention
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Augusta University
Radiotherapy-Induced Oral Mucositis, Stomatitis
Traditional Chinese Medicine for the Prevention of Radiotherapy-Induced Oral Mucositis (RTOM)
This is a multicenter, randomized, controlled, prospective clinical trial designed to observe and evaluate the safety and efficacy of Modified Dahuang Huanglian Xiexin Mouthwash for the prevention of radiotherapy-induced oral…
- Conditions
- Radiotherapy-Induced Oral Mucositis, Stomatitis, Oral Mucositis, Radiotherapy Side Effects
- Trial name
- NCT07543978
- Testing
- Modified Dahuang Huanglian Xiexin Mouthwash
- Volunteers
- 156 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
PTSD, Post Traumatic Stress Disorder, Diagnosis, Psychiatric
The Efficacy of a Herbal Supplement in the Prevention of PTSD
Psycho-traumatic disorders are a disabling condition whose epidemiological data vary according to the country but also the populations studied and the measuring instruments used.
- Conditions
- PTSD, Post Traumatic Stress Disorder, Diagnosis, Psychiatric, Follow up
- Trial name
- PHYTéS (NCT03724448)
- Testing
- aleozen
- Where
- Tunisia
- Volunteers
- 200 people
- Sponsor
- Hôpital Universitaire Sahloul
Healthy Young Soccer Players
Efficacy of FIFA 11+ Kids Injury Prevention Program on Soccer-specific Skills Among Young Soccer Players
Background: Soccer is a prevalent sport worldwide; most soccer players are under 18. Soccer has benefits for your health, but there is also a chance that you could get injuries occasionally.
- Trial name
- NCT06501833
- Testing
- FIFA 11+ KIDS PROGRAM, REGULAR TRAINING
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Conditions or Focus of Study, Pressure Injury Prevention
AI-Supported E-Learning for Pressure Injury Prevention
Brief Summary Pressure injuries are damage to the skin and underlying tissue that may occur in patients who stay in bed for long periods, have limited mobility or use medical devices. These injuries are often preventable.
- Conditions
- Conditions or Focus of Study, Pressure Injury Prevention, Pressure Ulcer Prevention, Nursing Education
- Trial name
- NCT07658209
- Testing
- Face-to-Face Pressure Injury Prevention Education, AI-Supported Modular E-Learning Programme
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Kilis 7 Aralik University
Acute Kidney Injury(Postoperative Acute Kidney Injury in Patients Undergoing Aortic Surgery)
The Effect of Dexmedetomidine on Prevention of Postoperative Acute Kidney Injury in Patients Undergoing Aortic Surgery
Acute kidney injury(AKI) is a common and severe complication after the cardiac surgery. Postoperative AKI increases the in-hospital stay, intensive care unit(ICU) stay and postoperative mortality.
- Trial name
- NCT02607163
- Testing
- dexmedetomidine, saline
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Yonsei University
Mucositis, Head and Neck Cancer
Photobiomodulation Home-use Device for Prevention or Treatment of Oral Mucositis in Patients With Head&Neck Malignancies
Patients with head and neck malignancy that are treated with Radiation Therapy [RT] are expected to develop Oral Mucositis (OM) in 60% of cases.
- Conditions
- Mucositis, Head and Neck Cancer, Radiotherapy Side Effect
- Trial name
- PBM&OM-01 (NCT05176834)
- Testing
- B-Cure laser pro
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Erika Carmel ltd
Pressure Injury
Prevention to Pressure Injury With Care Bundle
Aim: The study was conducted in order to evaluate of pressure injury prevention care bundle application in intensive care unit patients diagnosed with internal diseases.
- Trial name
- NCT05541198
- Testing
- Pressure Injury Prevention Care Bundle
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Saglik Bilimleri Universitesi
Venous Thromboembolism, Pulmonary Embolism
A Different Approach to Preventing Thrombosis
The purpose of this study is to perform a pragmatic randomized controlled trial to compare the use of low molecular weight heparin (LMWH, lovenox, enoxaparin) versus acetylsalicylic acid (ASA) for venous thromboembolism (VTE)…
- Trial name
- ADAPT (NCT02774265)
- Testing
- VTE prophylaxis with Enoxaparin 30mg BID, VTE prophylaxis with Aspirin 81mg BID
- Where
- United States
- Volunteers
- 329 people
- Sponsor
- University of Maryland, Baltimore
Accidental Falls/Prevention and Control, Osteoporosis
Prevention of Injury in Skilled Nursing Facilities Through Optimizing Medications
The goal of this clinical trial is to compare three care models for optimizing medications and preventing falls with broken bones in patients receiving rehabilitation after a hospitalization for a broken bone.
- Trial name
- PRISM (NCT06304428)
- Testing
- Deprescribing Care Model, Bone Health Service Model, Injury Prevention Service Model
- Where
- 2 sites in United States
- Volunteers
- 3,780 people
- Sponsor
- Duke University
Burns
Prevention of Posttraumatic Stress Symptoms in Young Children With Burns: a Randomized Controlled Trial
Background: Previous studies have found considerable rates of posttraumatic stress disorder (PTSD) or clinically relevant posttraumatic stress symptoms (PTSS) in preschoolers with injuries following accidental trauma.
- Trial name
- EPICAP (NCT02088814)
- Testing
- 'EPICAP'
- Where
- Switzerland
- Volunteers
- 57 people
- Sponsor
- University Children's Hospital, Zurich
Parkinson Disease, Osteoporosis
Trial of Parkinson's And Zoledronic Acid
This home-based study is a randomized (1:1) placebo-controlled trial of a single infusion of zoledronic acid-5 mg (ZA) for the prevention of fractures in men and women aged 60 years and older with Parkinson's disease and…
- Conditions
- Parkinson Disease, Osteoporosis, Parkinsonism, Parkinson's Disease and Parkinsonism
- Trial name
- TOPAZ (NCT03924414)
- Testing
- Zoledronic Acid 5Mg/Bag 100Ml Inj
- Where
- 77 sites in United States
- Volunteers
- 2,721 people
- Sponsor
- California Pacific Medical Center Research Institute
NSAID-induced Gastroduodenal Injury, Ulcers
Cobiprostone Prevention of NSAID-induced Gastroduodenal Injury
The primary purpose of this study is to determine the efficacy and safety of three dose levels of cobiprostone as compared to placebo in OA/RA patients treated with an NSAID for 20 months.
- Conditions
- NSAID-induced Gastroduodenal Injury, Ulcers, Rheumatoid Arthritis, Osteoarthritis
- Trial name
- NCT00597818
- Testing
- Cobiprostone, Non-steroidal anti-inflammatory drug
- Where
- 19 sites in United States
- Volunteers
- 121 people
- Sponsor
- Sucampo Pharma Americas, LLC
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