Clinical trials: Trauma Prevention
Injury;Sports
Acute Effect of Motor-Cognitive Training
Participants will complete a functional MRI to evaluate brain activation, functional connectivity, and behavioral performance immediately before and after a training program (approximately 30 minutes).
- Trial name
- NCT06017154
- Testing
- Motor-Cognitive Training Program
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ke'La H Porter
Pressure Injury, Hospital Acquired Pressure Ulcer
Development of a Nursing Care Bundle to Prevent Pressure Injuries and Its Impact on Rates and Costs
Pressure injuries (PIs) represent a significant clinical complication for patients worldwide and pose financial and quality challenges for healthcare systems.
- Trial name
- NCT06770686
- Testing
- Intervention Group, Control Group
- Volunteers
- 90 people
- Sponsor
- Koç University
Surgical Site Infection
Study for Antibiotic Impregnated Calcium Sulfate Beads as Prophylaxis for Surgical Site Infection
The CDC quotes a rate of wound infection of 2-5% for inpatient surgery. Patients undergoing a vascular operation, however, are generally at an increased risk of wound infection with rates often close to 5-10%.
- Trial name
- NCT03308253
- Testing
- Stimulan Rapid Cure, Vancomycin, Tobramycin
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- McMaster University
Endophthalmitis, Trauma, Corneal
Use Of Intracameral Moxifloxacin For Prophylaxis Of Open Globe Endophthalmitis
Endophthalmitis is a severe inflammatory eye condition with profound impairment of vision, which can lead to irreversible visual loss and requires immediate treatment.
- Trial name
- NCT05079854
- Testing
- Intraocular Instillation Solution, Moxifloxacin Ophthalmic
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Federal University of São Paulo
Spinal Cord Injury
Nutrition Education for Cardiovascular Disease Prevention in Spinal Cord Injury
This is a randomized controlled trial to study a nutrition education intervention in individuals with spinal cord injuries both in the acute rehabilitation setting (n = 100) and the community setting (n = 100).
- Trial name
- NCT02368405
- Testing
- Control, Eat Smart, Live Better
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Spinal Cord Injuries, PTSD
Brief Prolonged Exposure Therapy Versus Clinical Standard to Reduce Posttraumatic Stress Post Spinal Cord Injury
This study will examine the use brief prolonged exposure (Brief PE) therapy compared to standard clinical care to reduce posttraumatic distress among people who have had a spinal cord injury and are receiving rehabilitation in an…
- Conditions
- Spinal Cord Injuries, PTSD, Post-Traumatic Stress Disorder
- Trial name
- NCT05233111
- Testing
- Brief Prolonged Exposure Therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Baylor Research Institute
Contrast Medium-induced Nephropathy
Prevention of Contrast Renal Injury With Different Hydration Strategies
Using a randomized controlled trial design, two hydration protocols for the prevention of contrast medium-induced nephropathy will be tested.
- Trial name
- POSEIDON (NCT01218828)
- Testing
- LVEDP -Based hydration strategy, Standard hydration
- Where
- United States
- Volunteers
- 396 people
- Sponsor
- Kaiser Permanente
Stress Disorders, Post-Traumatic
Secondary Prevention With Paroxetine vs. Placebo in Subthreshold Posttraumatic Stress Disorder (PTSD)
The purpose of this study is: 1) To document the effectiveness and tolerability of paroxetine for the treatment of subthreshold posttraumatic stress disorder (PTSD) in veterans in the early post-deployment period; and 2) To…
- Trial name
- NCT00560612
- Testing
- Paroxetine
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Durham VA Medical Center
Musculoskeletal Injury
Running Online Injury Prevention Feasibility Study
The main purpose of this study is to test the feasibility of a larger scale interventional study. The investigators want to understand whether data can be reliably collected data various different streams while participants…
- Trial name
- ROIPF (NCT06538363)
- Testing
- Education, Generic Education
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Falls
No More Falls Injury Prevention Study
A randomized controlled multi-component fall prevention study for older adults. The study integrates fall prevention into an existing community-based public health program for older adults.
- Trial name
- NCT00164632
- Testing
- counselling, exercise, referrals (behavior)
- Volunteers
- 552 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Mental Disability, Mothers
The Effect of Home Accidents Prevention Training Given to Mothers of Mentally Disabled Children
The aim of this research is to examine the effect of education for home accidents given to mothers with mentally disabled children in the age group of 0-6.
- Conditions
- Mental Disability, Mothers, Home Injury
- Trial name
- NCT06633549
- Testing
- Home Accidents Prevention Training, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Healthy
Preventive Treatment of Groin Pain in Football
Groin pain represents a common issue in football. Currently, there are no prevention protocols demonstrating real effectiveness.
- Trial name
- NCT05713487
- Testing
- preventive treatment group
- Where
- Italy
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universita degli Studi di Genova
Pressure Injury
Comparing Aloe Vera Gel and Rosemary Oil in Pressure Injury Prevention
Most patients admitted to the orthopedic ward are at risk of developing pressure ulcers. Today, the tendency to use medicinal herbs in pressure ulcer treatment has increased due to the variety of effective compounds and their…
- Trial name
- NCT05578638
- Testing
- Aloe Vera rosemary tropical application, aloevera tropical application, rosemary tropicalapplication
- Where
- Egypt
- Volunteers
- 128 people
- Sponsor
- Mansoura University
Surgical Site Infection, Sternal Infection
D-PLEX 302: Efficacy and Safety of D-PLEX in the Prevention of Sternal Infection Post Cardiac Surgery
Prospective, Multinational, Multicenter, Randomized, Parallel Controlled, Two arms, Single Blind, Study to Assess the Efficacy and Safety of D-PLEX Administered Concomitantly with the Standard of Care (SOC) IV Prophylactic…
- Conditions
- Surgical Site Infection, Sternal Infection, Cardiac Surgery
- Trial name
- NCT03558984
- Testing
- D-PLEX, Standard of Care
- Where
- 3 sites in United States, Israel
- Volunteers
- 2 people
- Sponsor
- PolyPid Ltd.
Firearm Injury
Safety Education in the Emergency Department: A Pilot Study
The purpose of this pilot study is to assess the feasibility and acceptability of video-based safe firearm storage education in the Pediatric Emergency Department.
- Trial name
- SEED (NCT05168878)
- Testing
- 30-second BeSMART video, 3-minute BeSMART video
- Where
- United States
- Volunteers
- 407 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Hypertrophic
A Study of a Novel Silicone Dressing to Minimize Scar Formation
Neodyne has developed an investigational dressing for post-operative incision care. Neodyne is conducting this research to study whether the investigational dressing, called the Neodyne Dressing, can minimize scar formation in a…
- Trial name
- REFINE (NCT01399099)
- Testing
- embrace device
- Where
- 13 sites in United States
- Volunteers
- 67 people
- Sponsor
- Neodyne Biosciences, Inc.
Suicide, Firearm Injury
Emergency Room Firearm and Medication Safety Intervention
Seventeen United States Veterans die by suicide each day. Nearly three-fourths of those Veterans die from firearm injury or poisoning, and many seek care in VA Emergency Departments (ED) prior to suicide attempts.
- Conditions
- Suicide, Firearm Injury, Overdose
- Trial name
- NCT04797221
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- VA Office of Research and Development
Hydrocephalus, Ventriculoperitoneal Shunt Infection
Efficacy and Cost-Effectiveness of Topical Vancomycin Powder in Preventing Pediatric Ventriculoperitoneal Shunt Infections Across Different Etiologies
Objectives Primary: To measure the reduction in VP shunt infection rates using topical vancomycin powder. Secondary: To compare efficacy across different Etiological Strata (Congenital, Post-hemorrhagic, post-inflammatory).
- Conditions
- Hydrocephalus, Ventriculoperitoneal Shunt Infection, Surgical Site Infection (SSI), Cerebrospinal Fluid Shunt Infection
- Trial name
- NCT07547826
- Testing
- Topical Vancomycin Powder, Standard Perioperative Care
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Assiut University
Wound; Rupture, Surgery, Cesarean Section, Postpartum Hemorrhage
HEMOLEVEN® Expanded Access Program Prevention of Surgical/Postpartum Hemorrhage Severe Inherited Factor XI Deficiency
The objective of the Expanded Access Program is to provide HEMOLEVEN, a replacement coagulation factor XI, to patients with severe inherited factor XI deficiency where, in the opinion of the treating physician, the benefits of…
- Conditions
- Wound; Rupture, Surgery, Cesarean Section, Postpartum Hemorrhage, Surgery
- Trial name
- EAP (NCT01701947)
- Testing
- Hemoleven
- Where
- United States
- Sponsor
- Laboratoire français de Fractionnement et de Biotechnologies
Post-traumatic Stress Disorder
PTSD Prevention Study Examining the Efficacy of Sertraline in Burn Victims
This is a randomized, double-blind, placebo-controlled study to determine whether administration of sertraline to patients who exhibit acute stress disorder secondary to severe burns can contribute to the prevention of…
- Trial name
- NCT02520726
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Utah
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