Clinical trials: Trauma Prevention
Acute Renal Injury, Preventive Measures
Prevention and Early Detection and Intervention of Post-Coronary Artery Bypass Grafting Surgery (CABG) Acute Kidney Injury (AKI)
Nephrology participation in care of patients undergoing CABG could reduce AKI through correction of modifiable risk factors and early detection and intervention of post-op AKI.
- Trial name
- NCT02838667
- Testing
- Standard of Care plus Nephrology Care
- Where
- United States
- Volunteers
- 2,300 people
- Sponsor
- Mayo Clinic
Colon Cancer, Rectal Cancer
Comparison of Two Bundles of Care to Reduce Surgical Site Infection in Colorectal Surgery (CCR-VINCat 2)
There is controversy about the maximum number of elements to be included in a surgical site infection (SSI) prevention bundle and the possibility of its implementation at a multi-center level.
- Conditions
- Colon Cancer, Rectal Cancer, Surgical Site Infection
- Trial name
- CCR-VINCat2 (NCT06244836)
- Testing
- Implementation of a bundle of care
- Where
- Spain
- Volunteers
- 32,205 people
- Sponsor
- Hospital de Granollers
Surgical Wound Infection
Study of the Efficacy of Preoperative Cefuroxime Prophylaxis to Prevent Surgical Site Infection in Herniated Disk Surgery
The purpose of the study is to determine whether a single, pre-operative dose of cefuroxime is effective in preventing surgical site infection in patients undergoing surgery for herniated disk
- Trial name
- NCT00530400
- Testing
- cefuroxime
- Where
- 2 sites in Switzerland
- Volunteers
- 1,369 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Corneal Scars and Opacities
Limbus-derived Stem Cells for Prevention of Postoperative Corneal Haze
This is a investigator-initiated pilot clinical trial to ascertain the safety and efficacy of application of ex-vivo cultivated limbal stem cells in human eyes for treating Corneal Haze after Photo-Therapeutic/Refractive…
- Trial name
- NCT03295292
- Testing
- Stem cells, Vehicle
- Where
- India
- Volunteers
- 15 people
- Sponsor
- L.V. Prasad Eye Institute
Posttraumatic Stress Disorder, Acute Stress Disorder
Prevention of Intrusive Memories and Posttraumatic Stress Symptoms After Emergency Cesarean Section
This pilot study aims to investigate the effects of a brief computerized intervention (the computer game "Tetris") on intrusive memories and other posttraumatic stress symptoms following an emergency cesarean section.
- Trial name
- NCT02502513
- Testing
- Brief computerized intervention
- Where
- Switzerland
- Volunteers
- 56 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Pregnancy, Sexually Transmitted Infections
Teen Video Study to Reduce Risky Driving and Sexual Behavior in Adolescents
The purpose of this study is to measure the effects of an interactive video on adolescent risky behaviors and outcomes, with one video intended to reduce teen pregnancies and the other intended to reduce automobile accidents.
- Conditions
- Pregnancy, Sexually Transmitted Infections, Automobile Accidents
- Trial name
- TVS (NCT02049710)
- Testing
- Seventeen Days, Driving Skills for Life
- Where
- 3 sites in United States
- Volunteers
- 1,317 people
- Sponsor
- Carnegie Mellon University
Kidney Diseases, Dialysis; Complications
PRevEnting FracturEs in REnal Disease - 1
PREFERRED-1 is a pilot study designed to determine the feasibility of a large randomized, pragmatic, open-label, comparative-effectiveness trial of denosumab for the prevention of fragility fractures in people receiving…
- Conditions
- Kidney Diseases, Dialysis; Complications, Fragility Fracture, Chronic Kidney Disease-Mineral and Bone Disorder
- Trial name
- PREFERRED-1 (NCT05096195)
- Testing
- Denosumab 60 mg/ml, Calcium and vitamin D prophylaxis, Monitoring of post-injection calcium and phosphate
- Where
- 6 sites in Canada
- Volunteers
- 60 people
- Sponsor
- Western University, Canada
Running-related Injuries
The Effectiveness of a Running-related Injury Prevention Program in Runners
Running is effective in increasing levels of physical activity and promotes a number of beneficial health effects. However, running can lead to running- related injuries (RRI).
- Trial name
- NCT03892239
- Testing
- RunIn3 Prevention Program, Feedback Based Surveillance
- Where
- Brazil
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- Universidade Cidade de Sao Paulo
Alopecia, Radiodermatitis
Exploratory Study of Norepinephrine to Prevent Alopecia in Head and Neck Cancer Patients Treated With Radiotherapy
The study will evaluate the safety of topical norepinephrine in head and neck cancer patients who are receiving treatment with intensity modulated radiotherapy (IMRT).
- Trial name
- NCT01367990
- Testing
- Norepinephrine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- ProCertus BioPharm, Inc
Cardiovascular Complication, Cardiovascular Insufficiency
Reporting, Evaluating, Preventing and Treating the Cardiotoxicity Induced by Anticancer Drugs During a Specific Cardio-oncology Consult and Follow up in Routine Care
Several Drugs used in routine care in oncology induce rare but often severe or fatal cardiovascular or metabolic side effects. This study will investigate, evaluate, report and treat the cardiovascular side effects of anticancer…
- Conditions
- Cardiovascular Complication, Cardiovascular Insufficiency, Cardiac Complication, Oncologic Complications
- Trial name
- NEOCARDIO (NCT03882580)
- Testing
- Anti-Cancer Agents
- Where
- 3 sites in France
- Volunteers
- 5,000 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
High-intensity Strenght Training in Normoxia (H-N), Low-intensity Strenght Training in Normoxia (L-N)
Normobaric Hypoxia as a Strength Training Intensity Amplifier in Ice Hockey Players: Effects on Anaerobic Performance and Muscle Contraction Properties
The goal of this research study is to investigate the effects of resistance training performed under normobaric hypoxia (simulated altitude conditions) on anaerobic performance, lactate clearance, and muscle contractility in…
- Conditions
- High-intensity Strenght Training in Normoxia (H-N), Low-intensity Strenght Training in Normoxia (L-N), High-intensity Strenght Training in Normobaric Hypoxia (H-H), Low-intensity Strenght Training in Normobaric Hypoxia (L-H)
- Trial name
- NCT06930027
- Testing
- Resistance Training (High-Intensity), Resistance Training (Low-Intensity), Normobaric Hypoxia
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Ischemic Stroke
Intracerebral Hemorrhage Due to Oral Anticoagulants: Prediction of the Risk by Magnetic Resonance
The purpose of this study is to determine whether Magnetic Resonance Imaging may predict the risk of Intracerebral Hemorrhage for patients with ischemic stroke who receive indefinite oral anticoagulation
- Trial name
- HERO (NCT02238470)
- Testing
- oral anticoagulants
- Where
- 30 sites in Italy, Spain
- Volunteers
- 1,000 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Leg Injuries
Neuromuscular Training to Reduce Sports Injuries Among Children and Adolescents
Sports-related injuries are a serious concern for physically active children and adolescents. Previous research, including ours at Chicago public high schools, shows our neuromuscular training program, the Knee Injury Prevention…
- Trial name
- KIPP (NCT01406054)
- Testing
- neuromuscular exercises
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Accident Injury
Simulated Clinical Use Testing to Evaluate Sharps Injury Prevention Features of HTL-STREFA's Safety Lancets (Test C)
A simulated clinical use testing to evaluate the Medlance Plus and myLance sharps injury prevention feature in accordance with the FDA's guidance on medical devices with sharps injury prevention features.
- Trial name
- NCT04933461
- Testing
- Safety lancet
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- HTL-Strefa S.A.
HIV, Common Mental Health Problems
Mpata Yathu Trial for Young Women in Zambia
This randomized controlled trial evaluates Mpata Yathu ("Our Space"), a trauma-informed, church-based counseling intervention for adolescent girls and young women in Lusaka, Zambia who have experienced gender-based violence and…
- Conditions
- HIV, Common Mental Health Problems, PTSD - Post Traumatic Stress Disorder, Depression Disorder
- Trial name
- MYT (NCT07132905)
- Testing
- Mpata Yathu ("Our Space")
- Where
- 2 sites in Zambia
- Volunteers
- 180 people
- Sponsor
- University of California, San Francisco
Fall, Fall Injury
A Clinical Decision Support System and Patient Portal for Preventing Medication-related Falls in Older Patients
Falls in older adults represents a growing public health challenge. The use of certain medication is recognized as an important modifiable risk factor for falls.
- Conditions
- Fall, Fall Injury, Fall Patients, Accidental Fall
- Trial name
- ADFICE_IT (NCT05449470)
- Testing
- CDSS, Patient Portal
- Where
- 10 sites in Netherlands
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Surgical Site Infection, Cesarean Section; Infection
Aqueous vs Alcohol Chlorhexidine Skin Preparation for Prevention of Cesarean Section Wound Infections
This will be a single-center randomized control trial comparing the efficacy of two different formulations of Chlorhexidine surgical skin preparation in preventing cesarean section wound infections.
- Trial name
- NCT05920122
- Testing
- 2% Chlorhexidine gluconate with 70% alcohol, 4% Chlorhexidine Gluconate aqueous solution
- Where
- United States
- Volunteers
- 1,398 people, healthy volunteers welcome
- Sponsor
- Hyagriv Simhan
Obstetric Anal Sphincter Injury, Episiotomy Wound
Mediolateral Episiotomy and Obstetric Anal Sphincter Injuries in Instrumental Delivery
Literature is contradictory about the impact of mediolateral episiotomy during operative vaginal delivery in obstetric anal sphincter injuries prevention explaining the absence of international guidelines.
- Conditions
- Obstetric Anal Sphincter Injury, Episiotomy Wound, Anal Incontinence, Pelvic Floor Disorders
- Trial name
- INSTRUMODA (NCT04446780)
- Testing
- Mediolateral episiotomy
- Where
- France
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Muscle Injury
Muscle Injury Prevention & Rehabilitation in Military Personnel
The overall goal of this study is to establish a new pre-rehabilitation program in the prevention of muscle injury in the legs of healthy people serving in the military and injured individuals with muscle wasting following leg…
- Trial name
- NCT02077413
- Testing
- Healthy Muscle Group, Stretch-Contract Pre-rehabilitation Group, Stretch-Contract Control Group
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Florida
Acute Kidney Injuries, Kidney Injuries, Acute
Short Term Spironolactone for Prevention of Acute Kidney Injury After Cardiac Surgery
Our aim is to test whether short term perioperative administration of oral spironolactone could reduce incidence of postoperative acute kidney injury (AKI) in cardiac surgical patients.
- Conditions
- Acute Kidney Injuries, Kidney Injuries, Acute, Kidney Injury, Acute, Acute Renal Injury
- Trial name
- NCT02417896
- Testing
- Spironolactone
- Where
- 2 sites in Mexico
- Volunteers
- 150 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.