Clinical trials: Trauma Prevention
Injury Prevention
Stamp-in-Safety Playground Safety Project
Playground injuries are common at childcare centers. Adequate adult supervision is an important component to reducing playground injuries in preschool children.
- Trial name
- NCT00982917
- Testing
- Stamp-in-Safety Curriculum
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Child, Cerebral Palsy
Prevention of Hip Displacement in Children With Cerebral Palsy in Denmark
Children with cerebral palsy have an increased risk of hip dislocation, which is a painful and severe complication of cerebral palsy.
- Conditions
- Child, Cerebral Palsy, Radiography, Hip Dislocation
- Trial name
- NCT04403178
- Testing
- Radiographic examination with a Migration of > 40 %
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Mette Røn Kristensen
Strains
Acute Hamstring Strains in Danish Elite Soccer - Prevention and Rehabilitation
A common soft tissue injury in sports involving sprinting and jumping is the hamstring strain. Not much evidence-based research has been carried out on prevention of hamstring strains.
- Trial name
- NCT00557050
- Testing
- Training
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Amager Hospital
Individual Differences, Motor Activities
Screening of Athletes
Athletes have to participate in screenings in order to reduce injuries. Up-to-now most screenings are purely clinically based. Literature, however, indicates the importance of knowledge on deviant movement patterns as possible…
- Trial name
- NCT02056990
- Testing
- Advice
- Where
- Belgium
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Acute Kidney Injury Following Administration of Contrast Media
Comparison of Bolus and Continuous Hydration Regimens for the Prevention of Contrast-Associated Acute Kidney Injury in the Emergency Department
A single-center, prospective, open-label, non-inferiority randomized controlled clinical trial was conducted at the ED of a tertiary hospital.
- Trial name
- NCT07286526
- Testing
- Bolus hydration therapy, Continuous hydration therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 285 people
- Sponsor
- Yunus Emre Gemici
Perineal Trauma, Obstetric Anal Sphincter Injury
Papaverine for Prevention of Perineal Trauma
Perineal trauma is a common complication of vaginal delivery, particularly among primiparous patients, and may result in short- and long-term maternal morbidity, including pain, dyspareunia, and pelvic floor dysfunction.
- Trial name
- NCT07641543
- Testing
- Papaverine Hydrochloride
- Volunteers
- 412 people
- Sponsor
- Dr Raneen Abu Shqara
Athletic Injuries, Sports Injury Prevention
Evaluation of Injury Risk Factors and Effects of Individualized Exercise Program in Basketball and Volleyball Athletes
This study aims to identify injury risk factors using a clinical/functional test battery in university basketball and volleyball athletes, to develop individualized exercise prescriptions for athletes scoring below established…
- Conditions
- Athletic Injuries, Sports Injury Prevention, Musculoskeletal Injury
- Trial name
- IRISPORT (NCT07521215)
- Testing
- Test-Specific Individualized Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Acute Kidney Injury, The Changes of Plasma Creatinine
Short-Term Alpha Lipoic Acid Therapy for Prevention of Contrast-induced Acute Kidney Injury and Endothelial Dysfunction in Type 2 Diabetes
Contrast-induced acute kidney injury (CIAKI) is a major complication with adverse outcomes after contrast media injection. Although the risk of developing CIAKI is low in patients with normal renal function, it is dramatically…
- Conditions
- Acute Kidney Injury, The Changes of Plasma Creatinine, The Changes of Plasma Free Radicals, The Changes of Endothelium-dependent Arterial Dilation
- Trial name
- NCT01978405
- Testing
- Alpha lipoic acid
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xiang Guang-da
Chronic Kidney Disease
Efficacy Trial of N-Acetylcysteine and Sodium Bicarbonate for the Prevention of Contrast-Induced Acute Kidney Injury
Contrast-Induced Acute Kidney Injury(CIAKI) was defined as an absolute increase in serum creatinine of more than or equal to 0.3mg/dl (≥ 26.4 μmol/l), a percentage increase in serum creatinine of more than or equal to 50%…
- Trial name
- PREKIT (NCT01210456)
- Testing
- Physiological Saline, N-Acetylcysteine and Sodium Bicarbonate
- Where
- Japan
- Volunteers
- 458 people
- Sponsor
- Tokushukai Medical Group
Surgical Site Infection, Gynecologic Cancer
Effectiveness of Wound Drains for the Prevention Of Surgical sITe infectION
The aim of the present randomized trial is to assess the efficacy of wound drains in terms of reducing the rates of surgical site infection in obese patients with gynecological cancer.
- Conditions
- Surgical Site Infection, Gynecologic Cancer, Wound Drain
- Trial name
- POSITION (NCT05179122)
- Testing
- Surgical drain
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
PTSD, Alcohol Abuse
Sequence of Symptom Change During AUD or PTSD Treatment for Comorbid PTSD/AUD
The broad, long-term objective of the current research is to improve treatment outcomes for individuals with comorbid posttraumatic stress disorder (PTSD) and alcohol abuse and dependence (AUD).
- Conditions
- PTSD, Alcohol Abuse, Alcohol Dependence
- Trial name
- NCT01663337
- Testing
- Cognitive Processing Therapy (CPT), Relapse Prevention (RP)
- Where
- 2 sites in United States
- Volunteers
- 235 people
- Sponsor
- University of Washington
Radiodermatitis, Breast Cancer
Photobiomodulation Therapy for the Prevention of Acute Radiodermatitis in Breast Cancer Patients Undergoing Radiotherapy
Radiodermatitis (RD), an inflammatory skin reaction, occurs in more than 90 percent of cancer patients treated with radiotherapy (RT). This is the result of the radiation causing damage to the epidermal basal skin stem cells.
- Trial name
- LABRA (NCT03924011)
- Testing
- Photobiomodulation therapy (PBMT)
- Where
- 2 sites in Belgium
- Volunteers
- 71 people
- Sponsor
- Hasselt University
Lung Transplantation
Safety and Efficacy Study of Nitric Oxide in Patients Going Through Lung Transplantation
The purpose of this study is to assess the safety and efficacy of inhaled nitric oxide in prevention of lung graft dysfunction due to ischemia-reperfusion
- Trial name
- NCT00570245
- Testing
- Nitric oxide
- Where
- Spain
- Volunteers
- 49 people
- Sponsor
- Mallinckrodt
Osteoporotic Fractures, Osteoporosis, Postmenopausal
Zoledronic Acid for Osteoporotic Fracture Prevention (ZEST II)
The goal of this study is to perform the first fracture reduction clinical trial with a potent antiresorptive agent (intravenous zoledronic acid) in the most vulnerable long-term care population.
- Trial name
- ZEST II (NCT02589600)
- Testing
- Zoledronic acid, vitamin D, calcium
- Where
- United States
- Volunteers
- 310 people
- Sponsor
- Susan L. Greenspan
Surgical Site Infection (SSI), Spine Surgery
Investigation of the PREVENTIA® Irrigation Solution for Reducing Bacteria in Spinal Surgery With Implants - A Comparative Study
Spinal surgery carries a risk of surgical wound infections (i.e., the entry of bacteria). Despite various preventive measures, such infections continue to occur, particularly in operations involving implants.
- Conditions
- Surgical Site Infection (SSI), Spine Surgery, Surgical Site Infection Prevention
- Trial name
- PROTECT-SPINE (NCT07667036)
- Testing
- Preventia Surgical Solution, 0.9 % NaCl
- Where
- Switzerland
- Volunteers
- 114 people
- Sponsor
- Universität Luzern
Wound Infection, Wound Surgical
Efficacy of Negative Pressure Wound Closure Therapy by PICO System in Prevention of Complications of Femoral Artery Exposure
Evaluate negative pressure wound closure therapy by PICO system in Prevention of complications of femoral artery exposure.
- Trial name
- NCT04453319
- Testing
- Femoral Wound Closure and dressing
- Where
- Egypt
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Traumatic Brain Injury, Spinal Cord Injuries
Continuous Passive Motion Versus Heterotopic Ossification
The investigators hypothesize that Heterotopic Ossification (HO) formation can be suppressed if the application of a Continuous Passive Motion (CPM) device can be performed for a substantial amount of time.
- Conditions
- Traumatic Brain Injury, Spinal Cord Injuries, Stroke
- Trial name
- CPMversusHO (NCT05906056)
- Testing
- Continuous Passive Motion (CPM), Conventional physiotherapy (PT), Zoledronic Acid Injection
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- University of Ioannina
Students, Nursing
The Effect of Pressure Ulcer Prevention Training Delivered to Nursing Students Using the Pecha Kucha Technique
This study will be conducted to evaluate the effect of pressure injury prevention training delivered to nursing students using the Pecha Kucha technique on their levels of satisfaction with stage identification, knowledge, and…
- Trial name
- 7845 (NCT07797465)
- Testing
- Pecha Kucha Presentation, PowerPoint Presentation
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Stress Disorders, Post-Traumatic
Prevention of Postpartum Traumatic Stress (PTSD) in Mothers With Preterm Infants.
The purpose of the study includes: 1. To develop a treatment manual and pilot test this treatment intervention which is designed to prevent and reduce psychological distress in parents who have infants hospitalized in the…
- Trial name
- NCT01307293
- Testing
- Cognitive behavior therapy
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Stanford University
Emotional Trauma, Child Mental Disorder
Reintegration of Children From Institutions in Azerbaijan
To prevent mental health problems among 7-12 children from orphanages reunited with their biological or extended families in Azerbaijan, this study will refine and test three evidence-based intervention approaches (a) family…
- Conditions
- Emotional Trauma, Child Mental Disorder, Child Maltreatment
- Trial name
- NCT05396625
- Testing
- Usual Care, Family Strengthening, Mental Health Screening, Referral and Connection to Services
- Where
- 2 sites in Azerbaijan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Chicago
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