Clinical trials: Trauma Wounds
Acute Musculoskeletal Disease, Sprains
Efficacy of Lidocaine Patch in Acute Musculoskeletal Pain in the Emergency Department
This study evaluates the addition of a lidocaine patch to ibuprofen in the treatment of acute musculoskeletal pains. Half of the participants will get only ibuprofen for their pain, while other half will receive lidocaine patch…
- Conditions
- Acute Musculoskeletal Disease, Sprains, Sprains and Strains, Injuries
- Trial name
- NCT03571737
- Testing
- Ibuprofen, Lidocaine Patch 4%
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Spinal Cord Injury
Functional Electrical Stimulation (FES) Driven Stepping in Individuals With Spinal Cord Injury
The research is being done to find out if Functional Electrical Stimulation (FES) stepping can improve the function of people with spinal cord injury that paralyzes.
- Trial name
- NCT01479777
- Testing
- FES Stepping (RT600 from Restorative Therapies, INC.)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Tibial Delayed Healing
Tibial Delayed Healing Pivotal Clinical Trial
Evaluate the INFUSE/MASTERGRAFT™ Delayed Healing Device as an alternative/replacement to autograft in the treatment of tibial delayed healing.
- Trial name
- NCT01016067
- Testing
- INFUSE/MASTERGRAFT, Autograft bone
- Where
- 16 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Medtronic Spinal and Biologics
Hypercatabolic Status Related to Severe Burn
Study of Tolerability and Efficacy of BVS857 in Severe Burn Subjects
Study of tolerability and efficacy of BVS857 in severe burn subjects over 8 weeks and 15 weeks
- Trial name
- NCT02074995
- Testing
- BVS857
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Novartis Pharmaceuticals
Mild Traumatic Brain Injury
High-Definition Transcranial Direct Current Stimulation (HD-tDCS) for Sensory Deficits in Complex Traumatic Brain Injury
Aim 1: To use magnetoencephalography (MEG) and magnetic resonance imaging (MRI) in Veterans and civilians with mild traumatic brain injury (mTBI) and sensory postconcussive symptoms (PCS) to demonstrate the mechanism of…
- Trial name
- NAVIGATE-TBI (NCT03799458)
- Testing
- Active High-definition transcranial direct current stimulation (HD-tDCS)
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Lung Injury, Acute, Respiratory Distress Syndrome, Adult
Study of Enbrel (Etanercept) for the Treatment Sub-Acute Pulmonary Dysfunction After Allogeneic Stem Cell Transplant
The purpose of this study is to determine the effectiveness of etanercept in the treatment of patients with sub-acute lung injury following a bone marrow transplant.
- Conditions
- Lung Injury, Acute, Respiratory Distress Syndrome, Adult, Bronchiolitis Obliterans
- Trial name
- NCT00141726
- Testing
- Etanercept
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Michigan Rogel Cancer Center
Burns, Sedation
Dexmedetomidine Cardiovascular Safety in Pediatric Burn Patients
Dexmedetomidine is a sedative drug approved for adult patients, intubated, in intensive care units. We are studying whether this drug is cardiovascularly safe in pediatric patients who have recently been burned.
- Trial name
- NCT00697788
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Massachusetts General Hospital
Traumatic Brain Injury
Advanced MRI Applications for Mild Traumatic Brain Injury - UCSF
This hypothesis-generating feasibility study compares mTBI Patients and Controls using advanced MRI Applications.
- Trial name
- TBI-2 (NCT02141360)
- Testing
- MRI Diagnostic
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- GE Healthcare
Pain, Burn Injury
The Effect of Neurontin on Pain Management in the Acutely Burned Patient
Burn patients have extreme pain. Opioids are the main agents used for analgesia. We therefore propose a single center study to fruther assess the efficacy of neuropathic agents in controlling the pain associated with acute…
- Trial name
- NCT01265056
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Lucy A Wibbenmeyer
Shift-Work Sleep Disorder, Insomnia
Fire Fighter Fatigue Management Program: Operation Healthy Sleep
Firefighters work some of the most demanding schedules known under highly stressful and demanding conditions. The need to work frequent extended shifts and long work weeks leads to acute and chronic partial sleep deprivation as…
- Conditions
- Shift-Work Sleep Disorder, Insomnia, Restless Leg Syndrome, Obstructive Sleep Apnea
- Trial name
- NCT01988129
- Testing
- Sleep disorders education and screening
- Where
- United States
- Volunteers
- 1,189 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
PTSD, Trauma
Neuroendocrine Risk for PTSD in Women
This study will test for effects of estradiol (E2) on PTSD symptoms and functional magnetic resonance imaging (fMRI) indicators of stress vulnerability, in naturally-cycling women who are not using hormonal birth control.
- Trial name
- NCT03973229
- Testing
- Estradiol patch
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- Emory University
Open Abdomen
ABRA Abdominal Closure System in Open Abdomen Management
For the last 20 to 30 years, damage control laparotomy and decompressive laparotomy have emerged as part of the armamentariums for treatment of complex abdominal trauma, abdominal compartment syndrome, and critically ill surgical…
- Trial name
- ABRA (NCT00754156)
- Testing
- ABRA Abdominal Closure System, V.A.C. Therapy, KCI ABThera
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Anna Rockich
ACL Tear
Effects of Blood Flow Restriction Rehabilitation After Anterior Cruciate Ligament Reconstruction
The study is a prospective randomized control trial consisting of subjects requiring ACL reconstruction with BTB autograft. Subjects were randomly divided into two groups following their inclusion in the study.
- Trial name
- NCT04484961
- Testing
- Blood flow restriction (BFR)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Traumatic Brain Injury
Study of Oxycyte in Severe Closed Head Injury
Brain damage as a result of decreased oxygen to the brain is found in 80% of patients that die with severe head injuries. Laboratory studies in animals and clinical trials have shown that increasing oxygen in the brain results in…
- Trial name
- NCT00174980
- Testing
- Oxycyte
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Tenax Therapeutics, Inc.
Rib Fractures
Continuous Intravenous Lidocaine Infusion Versus Placebo for Rib Fracture Analgesia
The current cornerstone of pain control for rib fractures is oral and intravenous opioids, especially in the form of patient-controlled analgesia (IV PCA), which are are associated with multiple adverse effects including…
- Trial name
- NCT04140396
- Testing
- Saline infusion, Lidocaine infusion
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Stanford University
Head Trauma
Pain in Traumatic Brain Injury - Basile, MD
The observation through a chart review of persistent pain on neuro psychological functioning and how it applies to the community integration with patients that had suffered traumatic brain injury.
- Trial name
- NCT01136486
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Northwell Health
Brain Injury
Neural Bases of Cognitive Rehabilitation for Brain Injury
Some of the most common and disabling consequences of brain injury are deficits in cognition, such as difficulty with sustained attention, memory, organization, and goal management.
- Trial name
- NCT01120756
- Testing
- Goal-oriented attentional self-regulation, Brain Health Education
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cervical Spondylotic Myelopathy
Postural Stability in Cervical Spinal Myelopathy
Veterans are at heightened risk of developing cervical spondylotic myelopathy (CSM) from rigors of military service. Balance and posturography are negatively affected in CSM, but require expensive equipment, and extensive…
- Trial name
- NCT03810781
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
ACL Injury, Postoperative Pain
Ketorolac as an Adjuvant Agent for Postoperative Pain Control Following Arthroscopic ACL Surgery
1. The investigators aim to examine the use of IV and oral ketorolac as an adjunctive agent to the standard of care pain protocol for postoperative pain control following ACL reconstruction surgery. 2.
- Trial name
- NCT04246554
- Testing
- Ketorolac, Oxycodone-Acetaminophen
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Burns
CONTINUED ACCESS PROTOCOL: Demonstration of the Safety and Effectiveness of ReCell® Combined With Meshed Skin Graft for Reduction of Donor Area in the Treatment of Acute Burn Injuries
The overall purpose of this is study to provide continued access to the ReCell device following completion of protocol CTP001-6, and allow for collection of supplementary clinical outcome data for the ReCell device when used as…
- Trial name
- NCT02994654
- Testing
- ReCell
- Where
- 6 sites in United States
- Volunteers
- 12 people
- Sponsor
- Avita Medical