Clinical trials: Trauma and Stress-related Disorders
Post Traumatic Stress Disorder
Web-administered STAIR for Patients on Behavioral Health Waitlists
Posttraumatic stress disorder (PTSD) is a significant public health challenge with population prevalence rates in the US between 6.1 to 9.2%.
- Trial name
- webSTAIR (NCT06431022)
- Testing
- webSTAIR, CHW coaching
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Boston Medical Center
PTSD
Evaluation of an Algorithm for the Identification of Post-traumatic Stress Disorder
Post-traumatic stress disorder (PTSD) develops after a threat for oneself and/or others. It is frequent, particularly in the military, due to repeated exposure to traumatic events.
- Trial name
- Dstress (NCT06796556)
- Testing
- virtual reality exposition
- Where
- France
- Volunteers
- 134 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Patellofemoral Pain Syndrome, Medial Tibial Stress Syndrome
Do Simple Running Technique Changes Reduce Pain and Change Injury Causing Mechanics
This project aims to investigate whether an increase in step rate can be used to reduce pain and injury causing movement patterns in runners who are currently experiencing achilles tendonopathy, iliotibial band syndrome…
- Conditions
- Patellofemoral Pain Syndrome, Medial Tibial Stress Syndrome, Iliotibial Band Syndrome, Achilles Tendinopathy
- Trial name
- NCT03067545
- Testing
- Step rate increase
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Salford
PTSD
Non-invasive Nerve Stimulation and Sleep
People often have difficulty sleeping. Reasons are many. But, difficulty falling and staying asleep are common issues. Sleep difficulties are common in disorders such as Post Traumatic Stress Disorder.
- Trial name
- NINS (NCT04021537)
- Testing
- non-invasive nerve stimulation
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Efficacy of Yoga for Treatment-Resistant Posttraumatic Stress Disorder
The central question in this research proposal is: can a popular technique that specifically targets active mastery and improved affect regulation, yoga, which is utilized by approximately 4% of the US population each year (1)…
- Trial name
- NCT00839813
- Testing
- Yoga
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Justice Resource Institute
Trauma and Stressor Related Disorders
Effects of "Alliance180 Program" on Well-Being
The goal of this clinical trial is to evaluate the effects of the Alliance180 Program on physical and psychological well-being on adults who are/were US Veterans, First Responders and/or Front Line Healthcare Workers.
- Trial name
- NCT06451523
- Testing
- Alliance180 Program
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of North Carolina, Chapel Hill
Major Depressive Disorder, Depression
Testing a Transdiagnostic TMS Treatment Target
The goal of this clinical trial is to test a new brain stimulation treatment target for individuals with depression plus at least one additional psychiatric disorder.
- Conditions
- Major Depressive Disorder, Depression, Psychiatric Disorder, Mood Disorders
- Trial name
- T5 (NCT06282146)
- Testing
- transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Brigham and Women's Hospital
Posttraumatic Stress Disorders
Ifenprodil Tartrate Treatment of Adolescents With Post-traumatic Stress Disorder: a Double-blind, Placebo-controlled Trial
Accumulating evidence suggests a key role of the N-methyl-D-aspartate (NMDA) receptor in the pathophysiology of post-traumatic stress disorder (PTSD).
- Trial name
- NCT01896388
- Testing
- Ifenprodil Tartrate
- Where
- Japan
- Volunteers
- 10 people
- Sponsor
- Chiba University
PTSD, Overweight
MOVE!+UP: Testing a Tailored Weight Management Program for Veterans With PTSD
Posttraumatic Stress Disorder (PTSD) is common among Veterans and results in poor psychological functioning, quality of life, and physical health.
- Conditions
- PTSD, Overweight, Obesity
- Trial name
- NCT04563741
- Testing
- MOVE!+UP, MOVE!
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- VA Office of Research and Development
PTSD
Chilipad for Sleep and Symptoms of PTSD
The purpose of this study is to obtain pilot data in preparation for future research designed to formally evaluate the effectiveness of the Chilipad for patients with PTSD
- Trial name
- NCT03924297
- Testing
- chilipad
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
PTSD
Transcendental Meditation in Veterans and First Responders With PTSD
The present study is part of a Phase 3 multi-site clinical trial that will recruit veterans and first responders diagnosed with PTSD, where they will be randomized to receive either Transcendental Meditation (TM) or Present…
- Trial name
- NCT05645042
- Testing
- Transcendental Meditation (TM), Present Centered Therapy (PCT)
- Where
- 5 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
Posttraumatic Stress Disorder
A Controlled Trial of Losartan in Posttraumatic Stress Disorder
This study is being conducted to determine if losartan, an angiotensin receptor blocker (ARB), is safe and effective in the treatment of posttraumatic stress disorder (PTSD) symptoms.
- Trial name
- LOSe-PTSD (NCT02709018)
- Testing
- losartan
- Where
- 6 sites in United States
- Volunteers
- 149 people
- Sponsor
- University of California, San Diego
Post-traumatic Stress Disorder (PTSD), Trauma
Kappa Opioid Receptor Imaging in Post-traumatic Stress Disorder (PTSD)
This study uses positron emission tomography (PET) imaging to measure kappa opioid receptors (KOR) in the brains of individuals with and without post-traumatic stress disorder (PTSD).
- Trial name
- NCT02237703
- Testing
- Positron emission tomography (PET) imaging
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Posttraumatic Stress Disorder
Testing of a Mobile Web App to Decrease Posttraumatic Stress Symptoms in Women After Sexual Assault
Interventions are available to all adult women sexual assault survivors to reduce the risk of pregnancy and sexually transmitted infection, yet no interventions are provided to reduce posttraumatic stress.
- Trial name
- NCT04334356
- Testing
- Mobile Web App
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Posttraumatic Stress Disorder (PTSD)
Oxytocin and Affect Processing in Posttraumatic Stress Disorder
The investigators will use multiple methods (including Oxytocin intranasal inhalation, neuroimaging, behavioral measures, peripheral hormone measurements) to examine how individuals' behavior, cognition, and brain function is…
- Trial name
- NCT02546570
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Yale University
Stress Disorder - Post-traumatic (Acute)
Prevention of Post-traumatic Stress Disorder by Telephone Based Cognitive Behavioral Therapy
This is a randomized controlled study comparing telephone-based cognitive behavioral therapy (CBT) for recent survivors of traumatic events with Acute Stress Disorder (ASD) or acute PTSD with a waitlist control group.
- Trial name
- NCT00889005
- Testing
- Telephone Based Cognitive Behavioral Therapy
- Where
- Israel
- Volunteers
- 139 people
- Sponsor
- Hadassah Medical Organization
PTSD
Implementing PTSD Treatment in FQHCs for Michigan Medicaid Enrollees
The purpose of this project is to expand access to trauma-focused treatment among Medicaid Enrollees with PTSD, thereby improving the quality of mental health services delivered to this population.
- Trial name
- PE-PC Pilot (NCT03711266)
- Testing
- PE-PC
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- University of Michigan
Stress Disorders, Post-Traumatic
Prolonged Exposure Therapy for Post Traumatic Stress Disorder Following Sexual Assault
This study will evaluate the effectiveness of a brief cognitive behavioral therapy, administered by community agencies, for the treatment of patients with Post Traumatic Stress Disorder (PTSD).
- Trial name
- NCT00057629
- Testing
- Prolonged Exposure (PE), Treatment as usual group therapy (TUGT), Supportive counseling (SC)
- Where
- 2 sites in United States
- Volunteers
- 187 people
- Sponsor
- University of Pennsylvania
Emotion Regulation, Mood Disorders
Neurostimulation Versus Therapy for Problems With Emotions
The primary goal of this clinical trial is to evaluate the unique neural and behavioral effects of a one-session training combining emotion regulation skills training, with excitatory repetitive transcranial magnetic stimulation…
- Conditions
- Emotion Regulation, Mood Disorders, Stress Disorder, Anxiety Disorders
- Trial name
- NCT05712057
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), electrical scalp stimulation, Cognitive Restructuring
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Duke University
Pregnancy Loss
ACTRAMAT-D: Impact of Post-Traumatic Stress Disorder After Pregnancy Loss After 12 Weeks of Gestation
In France The prevalence of Pregnancy Loss after 12 weeks of gestation is around 3%. This situation is probably associated to a risk of post-traumatic stress disorder.
- Trial name
- ACTRAMAT-D (NCT03433989)
- Testing
- telephone interview
- Where
- France
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
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