Clinical trials: Trauma and Stress-related Disorders
PTSD
Chilipad for Sleep and Symptoms of PTSD
The purpose of this study is to obtain pilot data in preparation for future research designed to formally evaluate the effectiveness of the Chilipad for patients with PTSD
- Trial name
- NCT03924297
- Testing
- chilipad
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
PTSD
Clinician-Supported PTSD Coach vs. Self-Managed PTSD Coach
PTSD Coach is a mobile application (app) that aims to teach individuals self-management strategies for symptoms of Post-traumatic Stress Disorder (PTSD).
- Trial name
- NCT02400710
- Testing
- Clinician-Supported PTSD Coach, Self-Managed PTSD Coach
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Syracuse VA Medical Center
Fibromyalgia Syndrome, Posttraumatic Stress Disorder
Impact of Post-Traumatic Stress Disorder Treatment by Reconsolidation Therapy on Fibromyalgia Syndrome
The aim of the study is to demonstrate a significant improvement in quality of life specific to patients with fibromyalgia syndrome in patients with fibromyalgia syndrome with comorbid posttraumatic stress disorder, treated with…
- Trial name
- PTSD-FMS (NCT04950426)
- Testing
- Propranolol
- Where
- 2 sites in France
- Volunteers
- 17 people
- Sponsor
- Centre Hospitalier Henri Laborit
Restless Legs Syndrome, Multiple Sclerosis
Hypnosis and Direct Autonomic Experience Influence on Chronic Symptoms
Study will look at a limited number of participants with various chronic symptoms. Investigating a new and novel form of hypnosis application called "Direct Autonomic Experience (DAX)" which is using combination of visualization…
- Conditions
- Restless Legs Syndrome, Multiple Sclerosis, Trauma, Psychological, Chronic Disease
- Trial name
- HDAX1 (NCT04303143)
- Testing
- Self-Hypnosis, Direct Autonomic Experience Control
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Inner Group Inc.
Posttraumatic Stress Disorder, Depression
Yoga Breath Program and Client-Centered Exposure for Relief of PTSD in Tsunami Victims
Study hypothesis: that a standardized course of Eastern practices (Breath Water Sound Course -BWS) will significantly relieve PTSD and depression in tsunami victims.
- Trial name
- NCT00290225
- Testing
- Breath Water Sound Course and Traumatic Incident Reduction
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Victim Services Center, Miami
Stress Disorders, Post-Traumatic, Depressive Disorder, Major
The Effect of Traumatic Childbirth on the Incidence of PTSD and Other Major Postpartum Psychopathology
Determination of incidence and prevalence of PTSD and other types of psychopathology (such as anxiety and affective disorders) after traumatic birth experiences and elucidation of salient risk factors in the local population…
- Trial name
- NCT02370576
- Testing
- rating scale application
- Where
- Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Post-Traumatic Stress Disorder
Visual Dysfunction in Mild Traumatic Brain Injury (MTBI): A Comparison Group Study
In an on-going study of visual characteristics of personnel diagnosed with a mild traumatic brain injury (MTBI) related to their service in Iraq and Afghanistan we found a high rate of binocular vision problems (such as…
- Trial name
- VDMTBI (NCT00671450)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- US Department of Veterans Affairs
Dissociation
Mechanistic Interventions and Neuroscience of Dissociation
The purpose of this study is to test the neurophysiological mechanisms of an intervention to reduce symptoms of dissociation in traumatized people.
- Trial name
- MIND (NCT04670640)
- Testing
- Vibration, Breath Focus, No Distractions
- Where
- 2 sites in United States
- Volunteers
- 350 people
- Sponsor
- Emory University
Race-related Stress, Depression, Anxiety
Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease
The current study seeks to build on previous research that demonstrates the efficacy of Acceptance and Commitment Therapy in combating stigma by investigating the feasibility and acceptability of a protocol to support Black…
- Conditions
- Race-related Stress, Depression, Anxiety, Quality of Life, Stress Reaction
- Trial name
- ACT for SCD (NCT05685368)
- Testing
- ACT for SCD
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Children's Hospital Los Angeles
Post-Traumatic Stress Disorders
Eszopiclone for Sleep Disturbance and Nightmares in Post-Traumatic Stress Disorder
The purpose of this study is to obtain data investigating the safety and efficacy of eszopiclone for the treatment of post-traumatic stress disorder (PTSD)-related sleep disturbance and the impact of improved sleep with…
- Trial name
- NCT00120250
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Massachusetts General Hospital
Post-Traumatic Stress Disorder (PTSD), Depression
Transforming Trauma Care
This study evaluates the implementation and clinical effectiveness of the Trauma Resilience and Recovery Program (TRRP 2.0), a technology-enhanced behavioral health intervention designed for trauma center patients.
- Conditions
- Post-Traumatic Stress Disorder (PTSD), Depression, Substance Use Disorder, Traumatic Injury
- Trial name
- NCT07829510
- Testing
- Trauma Resilience and Recovery Program Portal 2.0 (TRRP 2.0)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Post Traumatic Stress Disorder, Depression
The Treatment of Traumatised Refugees With Sertraline Versus Venlafaxine in Combination With Psychotherapy
Background: The treatment of traumatised refugees is one of the areas within the field of psychiatry with the weakest evidence for the different types of treatment.
- Trial name
- PTF3 (NCT01569685)
- Testing
- Venlafaxine, Sertraline
- Where
- Denmark
- Volunteers
- 207 people
- Sponsor
- Charlotte Sonne
Post-Traumatic Stress Disorder
Use of Quetiapine as an Add on Therapy in the Treatment of Post Traumatic Stress Disorder
The purpose of this study is to evaluate how effective quetiapine versus placebo is when added to an existing therapy, in reducing the symptoms of PTSD.
- Trial name
- NCT00306540
- Testing
- Quetiapine Fumarate
- Where
- 3 sites in Australia
- Volunteers
- 90 people
- Sponsor
- AstraZeneca
Organ Donation, Next of Kin
Bernese Next of Kin Survey Following Organ Donation Request
6 to 18 months after organ donation request a next of kin survey using a standardized questionnaire was conducted.
- Conditions
- Organ Donation, Next of Kin, Post Traumatic Stress Disorder
- Trial name
- NCT03612024
- Testing
- questionnaire
- Where
- Switzerland
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Stress Disorders, Post-Traumatic
Novel Therapeutics in Posttraumatic Stress Disorder (PTSD): A Randomized Clinical Trial of Mifepristone
Posttraumatic stress disorder (PTSD) is a common and disabling psychiatric disorder for Veterans. Left untreated or under-treated, it can become a chronic condition associated with significant distress, depression, aggression…
- Trial name
- NCT01739335
- Testing
- Mifepristone Oral Tablet [Korlym]
- Where
- 5 sites in United States
- Volunteers
- 81 people
- Sponsor
- VA Office of Research and Development
Alcohol Use Disorder, Stress Reaction
Stress-related Predictor Profiles in Human Addiction
Long-term aim is the definition of a setup of mobile sensors and their integration in a mobile infrastructure that allows the prediction of stress related alcohol intake in an ambulatory setting.
- Conditions
- Alcohol Use Disorder, Stress Reaction, Social Stress, Craving
- Trial name
- NCT03810924
- Testing
- Trier Social Stress Test, Ergometer, Barlab-Exposure
- Where
- Germany
- Volunteers
- 121 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Posttraumatic Stress Disorder (PTSD), Substance Use Disorder (SUD)
The Many Roads to Trauma Recovery: A Clinical Trial Comparing Empirically Supported Treatments for Veterans With Co-Morbid Posttraumatic Stress and Substance Use Disorder Symptoms
Veterans with co-morbid posttraumatic stress disorder (PTSD) and substance use disorders (SUDs) are at substantial risk of developing hypertension and cardiovascular diseases that often lead to premature death, with some evidence…
- Trial name
- NCT07756723
- Testing
- Trauma Informed Heart Rate Variability Biofeedback, Present Centered Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Coatesville VA Medical Center
Posttraumatic Stress Disorder
Characterization of Recently Deployed Veterans
This study is a retrospective chart review of recently deployed veterans who served during the Iraq conflicts and were seen at the TVAMC in the outpatient Primary Care outpatient clinic that was recently set-up for newly…
- Trial name
- NCT00451659
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Tuscaloosa Research & Education Advancement Corporation
Posttraumatic Stress Disorder, Major Depressive Disorder
TF-CBT for Long-term PTSD, Major Depressive Disorder and Anxiety Disorders in Victims of Terrorism
The objective of this study is to test the efficacy of a Trauma-Focused Cognitive-Behavioural Therapy (TF-CBT) adapted for use with victims of terrorism in Spain who are diagnosed with posttraumatic stress disorder (PTSD), major…
- Conditions
- Posttraumatic Stress Disorder, Major Depressive Disorder, Anxiety Disorders
- Trial name
- NCT05516368
- Testing
- TF-CBT
- Volunteers
- 120 people
- Sponsor
- Universidad Complutense de Madrid
PTSD
Transcranial Magnetic Stimulation to Improve Functioning in Veterans With PTSD
Posttraumatic Stress Disorder (PTSD) is a common and serious condition affecting many Veterans. There are effective treatments for PTSD, but additional treatments are needed in order to better serve Veterans suffering from PTSD.
- Trial name
- rTMS for PTSD (NCT04207346)
- Testing
- TMS 1 hz
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- VA Office of Research and Development
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