Clinical trials: Trauma and Stress-related Disorders
Anxiety, Depression
Quality of Dying in the Intensive Care Unit: Validation of the CAESAR Scale
The purpose of the study is to evaluate the quality of the dying process in french ICUs (assessed by the CAESAR scale) and to compare physicians', nurses' and relatives perceptions and experiences, with a one-year follow-up of…
- Conditions
- Anxiety, Depression, Posttraumatic Stress Disorder
- Trial name
- CAESAR (NCT01549197)
- Where
- 47 sites in France
- Volunteers
- 475 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mild Traumatic Brain Injury
Quetiapine to Reduce Post Concussive Syndrome After Mild Traumatic Brain Injury (mTBI)
A two site, 2-arm, Phase III randomized pragmatic clinical trial evaluating the effectiveness of quetiapine monotherapy in comparison to Treatment As Usual (TAU) medication management for symptoms experienced by veterans…
- Trial name
- NCT06333990
- Testing
- Quetiapine Fumarate, TAU
- Where
- 2 sites in United States
- Volunteers
- 146 people
- Sponsor
- Foundation for Advancing Veterans' Health Research
Cardiovascular Disease, Post Traumatic Stress Disorder
Cardiovascular Risk Markers in Veterans With Post Traumatic Stress Disorder
This is an observational study designed to determine whether veterans with PTSD have a higher risk of heart disease than those without PTSD.
- Trial name
- CVMarkers (NCT01650220)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Stress Disorders, Post-Traumatic
A fMRI Study of the Treatment of Danish Veterans With PTSD With Prolonged Exposure Therapy
In this article, the investigators report the design and protocol of a functional magnetic resonance imaging study (fMRI) of the treatment of Danish veterans with PTSD with Prolonged Exposure Therapy (PE).
- Trial name
- NCT02519296
- Testing
- Prolonged Exposure Therapy, Observation, fMRI
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Post Traumatic Stress Disorder (PTSD), Depressive Symptoms
The Norwegian Stepped-Care TF-CBT Study
Every day, a significant number of children and young people in Norway experience violence, abuse, or other potentially traumatizing events.
- Conditions
- Post Traumatic Stress Disorder (PTSD), Depressive Symptoms, Parental Stress, Health Related Quality of Life
- Trial name
- NCT04073862
- Testing
- Stepped-Care TF-CBT
- Where
- Norway
- Volunteers
- 82 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
PTSD, Post-traumatic Stress Disorder
Deep Brain Reorienting in Post-traumatic Stress Disorder
This study will evaluate the efficacy of a therapeutic treatment, Deep Brain Reorienting (DBR), for PTSD (Post-traumatic Stress Disorder). Participants will be randomized to either the DBR treatment, or wait-list condition.
- Trial name
- NCT04317820
- Testing
- Deep Brain Reorienting (DBR)
- Where
- Canada
- Volunteers
- 234 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Stress Disorders, Post-Traumatic
Trial of Paroxetine-CR for the Treatment of Patients With Post Traumatic Stress Disorder Remaining Symptomatic After Initial Exposure Therapy
The purpose of the study is to evaluate the effectiveness and tolerability of controlled-release paroxetine (Paxil-CR) compared to placebo (an inactive substance) for individuals who continue to have symptoms of post traumatic…
- Trial name
- NCT00121888
- Testing
- Prolonged Exposure Therapy, Paroxetine-CR
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
PTSD, Alcohol; Use, Problem
Evaluating Signs of Safety: A Deaf-Accessible Therapy Toolkit for AUD and Trauma
The U.S. Deaf community - a group of more than one million Americans who communicate using American Sign Language (ASL) - experiences nearly triple the rate of lifetime problem drinking and twice the rate of trauma exposure…
- Trial name
- NCT06278922
- Testing
- Seeking Safety + Signs of Safety toolkit, Treatment as usual
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Massachusetts, Worcester
Posttraumatic Stress Disorder
Group vs. Individual Cognitive Processing Therapy for Combat-related PTSD
The purpose of this study is to conduct a randomized controlled trial to compare group and individual CPT-C for the treatment of PTSD in OIF/OEF military personnel.
- Trial name
- NCT02173561
- Testing
- Group Cognitive Processing Therapy-Cognitive Only, Individual Cognitive Processing Therapy-Cognitive Only
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Duke University
Persian Gulf Syndrome
Mindfulness-Based Stress Reduction for Gulf War Syndrome
This pilot study is a two arm randomized, controlled clinical trial that evaluated whether a standardized Mindfulness-Based Stress Reduction (MBSR) intervention reduces symptoms associated with Gulf War Syndrome (GWS) more…
- Trial name
- NCT01267045
- Testing
- Mindfulness-based stress reduction
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- US Department of Veterans Affairs
Traumatic Brain Injury (TBI), Post Traumatic Stress Disorder (PTSD)
Effectiveness of a Driving Intervention on Safe Community Mobility for Returning Combat Veterans
The main objective of this study is to discern if an Occupational Therapy Driving Intervention (OT-DI) improves fitness to drive abilities of Combat Veterans and also investigate if results leads to reduced driving errors on the…
- Trial name
- NCT02765672
- Testing
- Driving Behavior Interview, Clinical Driving Assessment, Propensity for Angry Driving Scale
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- University of Florida
Sleep Apnea Syndromes, Insomnia Disorder
Apnea and Insomnia Relief Study
The purpose of this study is to determine whether a behavioral sleep treatment improves functioning and sleep in Veterans with posttraumatic stress disorder (PTSD).
- Conditions
- Sleep Apnea Syndromes, Insomnia Disorder, Stress Disorders, Post-Traumatic
- Trial name
- AIR (NCT04007796)
- Testing
- Apnea and Insomnia Relief (AIR), Sleep Education (SE)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Post Traumatic Stress Symptoms, PTSD
Nonattachment Training for Post Traumatic Stress Recovery
This pilot study aims to investigate the effectiveness of a novel, co-created intervention based on principles of nonattachment for individuals recovering from Post-Traumatic Stress (PTS). Objectives include: 1.
- Trial name
- NPTS (NCT06683027)
- Testing
- Nonattachment for Post Traumatic Stress
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Derby
Birth, First, Pregnancy Related
The Effect of the Continuous Midwifery Care Model on Birth Outcomes
It is the right of both the mother and her baby to receive the best care and give birth in the best way possible for every pregnant woman.
- Conditions
- Birth, First, Pregnancy Related, Newborn; Fit, Trauma, Psychological
- Trial name
- NCT06020339
- Testing
- The midwife-led continuous care model (MLCC)
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Posttraumatic Stress Disorder
Emotional Memory Reactivation in Posttraumatic Stress Disorder
Converging lines of evidence have implicated the amygdala in the pathophysiology of posttraumatic stress disorder. The primary purpose of our study is to assess the effect of propanolol, a beta adrenergic antagonism, on amygdala…
- Trial name
- VIVITRAU (NCT01239173)
- Testing
- AVLOCARDYL
- Where
- France
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Posttraumatic Stress Disorder, PTSD
Adaptive Decision-making And Personalized Treatment for PTSD (ADAPT-PTSD)
By doing this research project, the investigators hope to learn which strategies work best to help veterans who are not benefiting from their first PTSD treatment or not completing between-session homework assignments regularly…
- Trial name
- ADAPT-PTSD (NCT07176273)
- Testing
- Modular Cognitive Processing Therapy, Modular Prolonged Exposure Therapy, Step Down Treatment
- Where
- 4 sites in United States
- Volunteers
- 302 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Post Traumatic Stress Disorder (PTSD)
A Clinical Trial for Post Traumatic Stress Disorder
he purpose of this study is to test whether a medication, called mifepristone (commonly known as the ³Morning-After-Pill²), can help to prevent emotional problems after someone has survived a traumatic experience.
- Trial name
- MATTER (NCT00554177)
- Testing
- Medicane (mifepristone)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Antonia New
Stress Disorders, Post-Traumatic
Propranolol Reactivation Mismatch (PRM) Treatment for PTSD
The aim of the proposed work is to gather pilot data from an attempt to enhance the ability of propranolol reactivation (PR) to improve PTSD symptoms by incorporating into the design a mismatch (PRM) between what is expected and…
- Trial name
- NCT03652922
- Testing
- Reactivation Mismatch
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Awareness, Anesthesia, Post Traumatic Stress Disorder
Psychological Effect of Explicit Recall After Sedation (PEERS)
Awareness, or explicit recall, under sedation is often intended and expected by anesthesiologists and is assumed that does not associate with any sequelae.
- Conditions
- Awareness, Anesthesia, Post Traumatic Stress Disorder, Depression
- Trial name
- PEERS (NCT04747379)
- Where
- Canada
- Volunteers
- 2,500 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
PTSD, Chronic Pain
Preventing the Development of Chronic Pain: Treating PTSD at Acute Pain Onset
Although most people recover from acute pain (such as pain caused by injury, surgery, repetitive motion, or unknown causes), many people do not fully recover and will experience chronic pain.
- Trial name
- NCT05700279
- Testing
- Stellate Ganglion Block, Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 345 people
- Sponsor
- Rush University Medical Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.