Clinical trials: Trauma and Stress-related Disorders
Posttraumatic Stress Disorder
In-Home Exposure Therapy for Veterans With Post Traumatic Stress Disorder (PTSD)
This study examines clinical and process outcomes following variable length prolonged exposure (PE) for posttraumatic stress disorder (PTSD) delivered by one of three treatment modalities: home-based telehealth (HBT)…
- Trial name
- NCT03110302
- Testing
- Prolonged exposure
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Veterans Medical Research Foundation
Post-traumatic Stress Disorder (PTSD)
The Effect of Narrative Exposure Therapy Intervention on Post-traumatic Stress Dissorder and Personal Recovery in Refugees and Asylum Seekers of Sindiane Programme
Displaced people, like refugees or asylum seekers, have high rate of potentially traumatic events. PTSD is one of the most common psychiatric trouble in this population. It requires specialized support and psychosocial program.
- Trial name
- SINDIANE (NCT05407337)
- Testing
- Psychotherapy using Narrative Exposure Therapy (NET)
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Stress, Trauma
Exploring PTSD Symptoms, Barriers and Facilitators to Mindfulness
The purpose of this study is to investigate justice-involved Black/African American female adolescents' (JI BAFAs; N=35) self-reported outcomes: stress, posttraumatic stress disorder (PTSD), recidivism, etc., as well as their…
- Conditions
- Stress, Trauma, PTSD, HPA
- Trial name
- NCT06311188
- Testing
- ITR Healing intervention
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Post-traumatic Stress Disorder, Generalized Anxiety Disorder
Primary Care Intervention Strategy for Anxiety Disorders
This study will compare the effectiveness of an intervention strategy for the treatment of people with post traumatic stress disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder in the primary care…
- Conditions
- Post-traumatic Stress Disorder, Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder
- Trial name
- NCT00347269
- Testing
- Cognitive-behavioral therapy, Psychotropic medication optimization, Treatment as Usual
- Where
- 4 sites in United States
- Volunteers
- 1,004 people
- Sponsor
- University of Washington
Post Traumatic Stress Disorder
People Bereaved by Violent Death : Negative Event Biases and Temporal Perception
A violent death is defined by its brutality, unexpectedness and is secondary to an external cause (suicide, homicide, accident).
- Trial name
- PrEVENT (NCT05874362)
- Testing
- Diagnosis of depressive episode or post traumatic stress disorder, No diagnosis of depressive episode or post traumatic stress disorder
- Where
- France
- Volunteers
- 61 people
- Sponsor
- Hôpital le Vinatier
Posttraumatic Stress Disorder
Written Exposure Therapy for Posttraumatic Stress Disorder
Although evidence-based treatments for PTSD exist, a significant minority of individuals do not benefit from these treatments and many individuals to not seek treatment, citing barriers such as time commitment and expense of…
- Trial name
- WET (NCT01800773)
- Testing
- Written Exposure Therapy, Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Boston University
HIV Prevention, PTSD and Substance Use Disorder
Preventing HIV Among Native Americans Through the Treatment PTSD & Substance Use
Investigators will conduct a two-arm, comparative effectiveness randomized controlled trial of two culturally adapted, empirically based programs (EBP) - Narrative Exposure Therapy (NET) vs.
- Trial name
- NCT03112369
- Testing
- Narrative Exposure Therapy (NET), Motivational Interviewing w/Skills Training (MIST)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Washington
Posttraumatic Stress Disorder, Depression
Decreasing Youth Involvement in Violence in Burundi
The purpose of the current study is to examine the psychological well-being of youth within the context of participation in political violence during the 2015 election period in Burundi.
- Conditions
- Posttraumatic Stress Disorder, Depression, Aggression
- Trial name
- NCT02503488
- Testing
- Narrative Exposure Therapy for Forensic Offender Rehab, Treatment as Usual
- Where
- Burundi
- Volunteers
- 40 people
- Sponsor
- University of Konstanz
PTSD - Post Traumatic Stress Disorder
Diet and Microbiome Interactions: Application in Posttraumatic Stress Disorder in Adults Consuming Vegetable Drinks
The gut microbiome has been shown to impact various facets of human health, including mental health. Studies have shown that populations with more agrarian lifestyles tend to have fewer chronic diseases and mental health issues…
- Trial name
- DMAPS (NCT07107269)
- Testing
- Low diversity plant beverage (Functional Food Intervention), High diversity plant beverage (Functional Food Intervention)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Colorado State University
Chronic Pain, Depression
Resilience and Well-Being Pilot Study
It is common for Veterans with injuries, illnesses, or physical disabilities to experience depression, post-traumatic stress disorder (PTSD), chronic pain, and other concerns.
- Conditions
- Chronic Pain, Depression, PTSD, Injuries
- Trial name
- NCT03563820
- Testing
- Resilience and Well-Being Program
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- VA Puget Sound Health Care System
Post-traumatic Stress Disorder
Exercise Training to Improve PTSD Symptoms and Health in Older Veterans
Posttraumatic stress disorder (PTSD) is prevalent among military Veterans and is more than just a psychological condition; PTSD has profound negative impacts on health, function, and quality of life.
- Trial name
- NCT04199182
- Testing
- Exercise Training, Healthy Aging Attention Control (HA-ATC)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- VA Office of Research and Development
PTSD
Long-Term Safety and Effectiveness of MDMA-Assisted Therapy for PTSD
The goal of this long-term follow-up study is to measure how long effects of MDMA-assisted therapy last in participants with PTSD who were treated in a prior Phase 3 clinical trial of MDMA-assisted therapy.
- Trial name
- MPLONG (NCT05066282)
- Where
- 4 sites in United States, Canada and 1 more
- Volunteers
- 186 people
- Sponsor
- Resilient Pharmaceuticals
Depression, Anxiety
The Implantable Cardioverter-defibrillators (ICD)/Device Expectations, Adaptations, and Successes Study
The introduction of pacemakers and implantable cardioverter-defibrillators (ICDs) has substantially changed the medical and surgical management of patients with cardiac rhythm disease.
- Conditions
- Depression, Anxiety, Post-traumatic Stress Disorder
- Trial name
- IDEAS (NCT01040988)
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Boston Children's Hospital
Trauma, Psychological, Mental Disorder in Adolescence
Fuerte Program for Newcomer Immigrant Youth
The present study is a randomized control trial to evaluate the efficacy and effectiveness of a school-based group prevention program (Fuerte) in San Francisco Unified School District Public Schools.
- Conditions
- Trauma, Psychological, Mental Disorder in Adolescence, Adolescent - Emotional Problem
- Trial name
- Fuerte (NCT04156373)
- Testing
- Fuerte
- Where
- United States
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dementia, Brain Injuries
Building Better Caregivers Online: An Online Workshop for Caregivers of Those With Traumatic Brain Injury, Post Traumatic Stress Disorder, or Alzheimer's or Other Dementia
The workshop is a 6-week online workshop for caregivers of people with traumatic brain injury, post traumatic stress disorder, or dementia.
- Conditions
- Dementia, Brain Injuries, Stress Disorders, Traumatic
- Trial name
- NCT00799786
- Testing
- Building Better Caregivers Online Workshop
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Stanford University
Post-traumatic Stress Disorder
Trial of Hydrocortisone for Post-Traumatic Stress Disorder (PTSD)
Developing novel and effective pharmacologic interventions for this post-traumatic stress disorder is important. The investigators propose to replicate findings of an earlier published pilot study using low dose hydrocortisone as…
- Trial name
- NCT00706173
- Testing
- Hydrocortisone
- Where
- United States
- Sponsor
- University of California, San Diego
Stress Disorders, Post-Traumatic
Computational Assessment of GABA Receptor Modulation in PTSD
A substantial majority of Veterans with posttraumatic stress disorder (PTSD) continue to suffer even with the best current medications.
- Trial name
- NCT06852469
- Testing
- Lorazepam 1 mg tablet
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Evidence-Based Practices, CBT
A Hybrid Type 2 Trial of Trauma-Focused Cognitive Behavioral Therapy and a Pragmatic Individual-Level Implementation Strategy
This research project is a hybrid type 2 effectiveness-implementation trial that simultaneously examines (1) the effectiveness of a trauma-focused intervention for youth in the education sector and (2) the impact of a…
- Conditions
- Evidence-Based Practices, CBT, School Health Services, Trauma, Psychological
- Trial name
- NCT04451161
- Testing
- Beliefs and Attitudes for Successful Implementation in Schools (BASIS), Trauma-Focused Cognitive-Behavioral Therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- University of Washington
Posttraumatic Stress Disorder, Borderline Personality Disorder
Cognitive Processing Therapy (CPT) for Posttraumatic Stress Disorder and Borderline Personality Disorder (PTSD-BPD)
Posttraumatic Stress Disorder (PTSD) with co-occurring Borderline Personality Disorder (BPD) (i.e., PTSD-BPD) is common (as high as 58%), debilitating, costly, and limited treatment options available for this population.
- Trial name
- NCT04230668
- Testing
- Cognitive Processing Therapy with Suicide Risk Management, Treatment as Usual with Suicide Rick Management
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Palo Alto University
Stress Disorders, Post Traumatic
Mantram Repetition to Manage PTSD in Veterans
With ongoing war in Iraq, the incidence of posttraumatic stress disorder (PTSD) in combat veterans is increasing. Creation, implementation, and testing of new and innovative interventions are needed to provide additional options…
- Trial name
- NCT00120627
- Testing
- Mantram Repetition Program (MRP) plus Usual Care, Usual care consisting of medication and case management
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- US Department of Veterans Affairs
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