Clinical trials: Trauma and Stress-related Disorders
Domestic Violence, Post-Traumatic Stress Disorder
Mental Health Symptoms and Intimate Partner Violence
Using a touch screen computer, the researchers are screening emergency department patients for intimate partner violence and mental health issues.
- Conditions
- Domestic Violence, Post-Traumatic Stress Disorder, Depression
- Trial name
- NCT00166075
- Testing
- Computer screen with community resource printout
- Where
- United States
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- Emory University
Insomnia, Nightmares
Initial Study of Insomnia/Nightmare Group Treatment for Posttraumatic Stress Disorder (PTSD)
Many combat Veterans suffer from posttraumatic stress disorder (PTSD), an anxiety disorder that develops after an extremely stressful event or events. PTSD is associated with problems falling asleep or staying asleep.
- Conditions
- Insomnia, Nightmares, Posttraumatic Stress Disorder
- Trial name
- NCT01314612
- Testing
- Cognitive-Behavioral Insomnia and Nightmare Group
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Michael E. DeBakey VA Medical Center
Stress Disorders, Post-Traumatic, Intimate Partner Violence
Addressing the Health Concerns of VA Women With Sexual Trauma
Lifetime sexual trauma (ST) (i.e., behaviors that range from unwanted sexual touching to attempted or completed rape) is a significant social and public health problem among women Veterans.
- Conditions
- Stress Disorders, Post-Traumatic, Intimate Partner Violence, Alcohol-Related Disorders
- Trial name
- SHE (NCT02957747)
- Testing
- SHE
- Where
- 2 sites in United States
- Volunteers
- 153 people
- Sponsor
- VISN 17 Center of Excellence
Stress Disorders, Post-Traumatic, Substance-Related Disorders
Concurrent Treatment for Substance Dependent Individuals With Post-Traumatic Stress Disorder (PTSD)
This treatment intervention trial is designed for men and women with substance dependence and comorbid Post-Traumatic Stress Disorder (PTSD).
- Trial name
- NCT01365247
- Testing
- Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure, Relapse Prevention Treatment, Active Monitoring Control Group
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- The City College of New York
Covid-19, Family Members
Impact of Covid-19 Restrictive Measure on Anxiety, Depression and PTSD for Relatives of ICU Patients
To limit the pandemic Covid-19 infection, the French government imposed a closure of all Intensive Care Unit (ICU). The family's visitations are prohibited during active Covid -19 pandemic in 2020 and in 2021.
- Conditions
- Covid-19, Family Members, Critical Illness
- Trial name
- HAD-Covid (NCT04430049)
- Testing
- Covid ICU containment measures
- Where
- 11 sites in France
- Volunteers
- 811 people
- Sponsor
- University Hospital, Clermont-Ferrand
Unipolar Depression, Anxiety Disorder
Improve: Integrating Emotion Focused Components Into Psychological Therapy
The primary purpose of this study is to compare the efficacy of two treatment-as-usual (TAU) conditions: TAU with integration of emotion focused components (EFT) and TAU with focus on self-regulation (SR).
- Conditions
- Unipolar Depression, Anxiety Disorder, Adjustment Disorder
- Trial name
- Improve (NCT02822443)
- Testing
- Psychological therapy (PT) as TAU with integrated emotion focused components (TAU - EFT), Psychological therapy (PT) as TAU with focus on self-regulation (TAU - SR)
- Where
- Switzerland
- Volunteers
- 104 people
- Sponsor
- University of Bern
Mental Disorder, Depressive Disorder
Biological Classification of Mental Disorders
BeCOME intends to include at least 1000 individuals with a broad spectrum of affective, anxiety and stress-related mental disorders as well as 500 individuals unaffected by mental disorders.
- Conditions
- Mental Disorder, Depressive Disorder, Anxiety, Trauma and Stressor Related Disorders
- Trial name
- BeCOME (NCT03984084)
- Testing
- no intervention
- Where
- Germany
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Max-Planck-Institute of Psychiatry
Post-traumatic Stress Disorder (PTSD)
Transcranial Direct Current Stimulation (tDCS) Enhancement of Trauma-focused Therapy for Posttraumatic Stress Disorder
The purpose of this study is to test whether transcranial direct current stimulation (tDCS) can enhance the clinical efficacy of trauma-focused therapy for posttraumatic stress disorder.
- Trial name
- NCT01940549
- Testing
- Trauma Focused Therapy + tDCS
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Stress, Anxiety
Auriculotherapy Effectiveness on Stress and Anxiety in Nursing Student
Single-blind randomized controlled trial aimed to assess stress and anxiety levels in Nursing School students of Beneficence Portuguese Hospital and review the effectiveness of true and placebo auriculotherapy.
- Trial name
- NCT01420848
- Testing
- Auriculotherapy
- Where
- Brazil
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Borderline Personality Disorder, Posttraumatic Stress Disorder
FKBP5 Methylation and Childhood Emotional Abuse in Complex Posttraumatic Stress Disorder: Investigating the Relationship and Its Predictive Role in Therapy Outcome
The aim of this study is to investigate the role FKBP5 DNA methylation levels in patients suffering from complex posttraumatic stress disorder, who participated in a 12-weeks disorder-specific DBT-PTSD inpatient treatment.
- Trial name
- NCT06433843
- Testing
- Dialectical behavioral therapy for the treatment of posttraumatic stress disorder (DBT-PTSD)
- Where
- Germany
- Volunteers
- 29 people
- Sponsor
- University Hospital Tuebingen
Depressive Symptoms, Anxiety Symptoms
Culturally Adapted i-CBT for Farsi/Dari Speaking Migrants
The aim of this randomized controlled trial (RCT) is to investigate the effectiveness of a culturally adapted internet-based cognitive behavioral therapy (i-CBT) intervention in reducing symptoms of common mental health issues…
- Conditions
- Depressive Symptoms, Anxiety Symptoms, Grief, Psychological Trauma
- Trial name
- i-CBT (NCT06828276)
- Testing
- Culturally adapted i-CBT
- Where
- Sweden
- Volunteers
- 128 people
- Sponsor
- Karolinska Institutet
PTSD and Substance Use Disorder, Emotional Distress
Auricular Acupuncture on Emotional Distress in Service Members and Veterans With PTSD
Emotional distress (ED) refers to a state of mental suffering that significantly impairs an individual's ability to cope, often leading to a decline in overall well-being.
- Trial name
- NCT07021352
- Testing
- Ear acupuncture, Mindfulness therapy
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- United States Naval Medical Center, San Diego
Alcohol Use Disorder, Depression
The Network Study: Soldiers Connecting for Work and Health
This study will examine the efficacy of an internet-based brief intervention designed to reduce risky behavior in Soldiers as they transition from Active Duty into the civilian workforce as a Veteran.
- Trial name
- NCT04463225
- Testing
- Internet-Delivered Brief Intervention
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Cornell University
Alcohol Drinking Related Problems, Alcohol Use Disorders
Co-occurence of Mental Illness and Problematic Alcohol Use: an Internet-based Cognitive Behavior Therapy Intervention
The goal of this clinical trial is to learn if internet-based cognitive behavior therapy (ICBT ) works to treat co-occurent of problematic alcohol use and mental illness including mild to moderate symptoms of either depression…
- Conditions
- Alcohol Drinking Related Problems, Alcohol Use Disorders, Depressive Disorders, Mental Illness
- Trial name
- CoMiT (NCT06789250)
- Testing
- Internet-based cognitive behavior therapy
- Where
- 2 sites in Sweden
- Volunteers
- 240 people
- Sponsor
- Linkoeping University
Post Traumatic Stress Disorder, Major Depressive Disorder
Accelerated TMS to a Novel Brain Target in MDD and PTSD
This is a Clinical Trial designed to evaluate novel transcranial magnetic stimulation (TMS) methods for treating depression/PTSD. TMS is an FDA-approved procedure for treatment-resistant depression.
- Trial name
- NCT03114891
- Testing
- Transcranial Magnetic Stimulation (TMS), Task, fMRI-guided TMS target
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pennsylvania
Posttraumatic Stress Disorder (PTSD), Posttraumatic Stress Symptom
Deep Brain Reorienting for Posttraumatic Stress Disorder
The goal of this clinical trial is to learn if Deep Brain Reorienting (DBR) works to treat posttraumatic stress disorder (PTSD) symptoms in military veterans.
- Trial name
- NCT07840417
- Testing
- Deep Brain Reorienting, Treatment as Usual (TAU)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Alberta
Lower Urinary Tract Symptoms, Adjustment Disorders
Lower Urinary Tract Symptoms in Women and Adjustment Disorder
Our hypothesis that the prevalence of AD in uro-gynecologic patients with LUTS who are seeking medical help for their condition is higher than that of the general population (indicated by high scores at the ADNM-20; score above…
- Trial name
- LUTS and AD (NCT03444740)
- Testing
- ICIQ-FLUTS, ADMN-20
- Volunteers
- 100 people
- Sponsor
- Basel Women's University Hospital
Traumatic Brain Injury, Post Traumatic Stress Disorder
Using Real-Time Functional Brain Imaging to Enhance Recovery From TBI
In this randomized, controlled clinical trial, we will evaluate the effects of (1) a brain-training program that uses real-time neurofeedback in functional magnetic resonance imaging (fMRI) to allow people to learn how to gain…
- Trial name
- NCT01908647
- Testing
- RT fMRI, Cognitive Training, Control RT fMRI
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Van Boven, Robert W., M.D.
Post-traumatic Stress Disorder
Effectiveness of a Blended Care Parenting Intervention for Parents With PTSD (KopOpOuders-PTSD)
KopOpOuders-PTSD is a new preventive blended care intervention for parents with PTSD. The purpose of this study is to evaluate its effectiveness in improving parenting and preventing child mental health problems.
- Trial name
- NCT05237999
- Testing
- KopOpOuders-PTSD
- Where
- Netherlands
- Volunteers
- 142 people
- Sponsor
- Arkin
PTSD
Effects of Methylphenidate (Ritalin®) on the Neural Basis of Anxiety
In the present study, investigator will investigate the effects of methylphenidate (40 mg) on mPFC activity in healthy male volunteers during fear extinction using functional magnetic resonance imaging (fMRI).
- Trial name
- NCT02021214
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
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