Clinical trials: Trauma and Stress-related Disorders
PTSD
Quetiapine Treatment for Post-Traumatic Stress Disorder (PTSD)
The purpose of the study is to determine if quetiapine is effective in the treatment of PTSD.
- Trial name
- PTSD (NCT00237393)
- Testing
- Quetiapine
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Ralph H. Johnson VA Medical Center
Stress Disorders, Post-Traumatic
Train Your Brain: Neurofeedback Intervention for PTSD
The investigator's aim is to evaluate the efficacy of two types of neurofeedback treatments for PTSD symptoms reduction. Half of the participants will receive the current standard for PTSD neurofeedback care undergoing…
- Trial name
- NCT03858933
- Testing
- eBrainFit Platform
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Southern California
Trauma Exposure, Trauma
Comparative Effectiveness of SPARCS and Unified Protocol for Youth With Chronic Medical Conditions and Trauma-Related Distress
The goal of this clinical trial is to compare the effectiveness of trauma-focused therapies for improving mental health symptoms and daily functioning in youth with chronic medical conditions who have experienced psychological…
- Conditions
- Trauma Exposure, Trauma, Trauma and Stressor Related Disorder, Mental Health Functioning
- Trial name
- NCT07483333
- Testing
- Structured Psychotherapy for Adolescents Responding to Chronic Stress - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Individual
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Anthony Vesco
Aggressive Behavior, Post-Traumatic Stress Disorder
Treatment of Aggressive Behavior and Post-Traumatic Stress Disorder
Street children and children of vulnerable families in conflict or former conflict regions are often exposed to multiple traumatic events and situations in which they are forced to engage in violent behavior.
- Trial name
- NCT01519193
- Testing
- Narrative Exposure Therapy for violent offenders (NETvo)
- Where
- Burundi
- Volunteers
- 42 people
- Sponsor
- University of Konstanz
Posttraumatic Stress Disorder, Family Members
Testing a Peer-led Trauma-focused Intervention for Significant Others of Those With BPD
This project involves developing and piloting a peer-led intervention focused on posttraumatic stress symptoms for the family members and significant others of people with borderline personality disorder.
- Conditions
- Posttraumatic Stress Disorder, Family Members, Spouses
- Trial name
- NCT06135090
- Testing
- Trauma Recovery Program (official title TBD)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- York University
Hyperthermia, Fatigue; Heat
Work Design Interventions for Heat Resilience
The goal of this project is to compare different ways to schedule a workday to see if older workers should follow a specific work protocol to reduce strain on the heart and muscles.
- Conditions
- Hyperthermia, Fatigue; Heat, Work-Related Condition
- Trial name
- NCT06599788
- Testing
- Standard work pace, Reduced-pace work, Increased-pace work
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Post-traumatic Stress Disorder
Diary for Severe Trauma
Treatment of severe trauma patients includes intensive cares. Both trauma and intensive care may lead to a post-traumatic stress disorder and then to a decreased quality of life.
- Trial name
- Qualitrau (NCT02305303)
- Testing
- Diary
- Where
- France
- Volunteers
- 226 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Post Traumatic Stress Disorder
Efficacy of Single Dose IV Hydrocortisone in Post Traumatic Stress Disorder (PTSD) Prevention
This study is designed to test the hypothesis that a single Hydrocortisone intra venous injection within 6 hours post-trauma facilitates physiological recovery thereby preventing the development of Post Traumatic Stress Disorder…
- Trial name
- NCT00855270
- Testing
- Hydrocortisone
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health
Ambient air temperatures in Asian, Latin American, African, and Pacific climate hotspots have broken record highs in 2024, driven by man-made climate change. Solutions are needed to reduce heat exposure in communities.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06579950)
- Testing
- Cool roof
- Where
- 5 sites in Burkina Faso, Fiji and 3 more
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Post-Traumatic Stress Disorders
Early Intervention for Post Traumatic Stress Disorder (PTSD)
Over 150,000 soldiers are currently deployed in Iraq as part of Operation Iraqi Freedom (OIF), and 12% of returning OIF veterans have posttraumatic stress disorder (PTSD).
- Trial name
- NCT00641173
- Testing
- paroxetine
- Sponsor
- US Department of Veterans Affairs
Anxiety Disorders, Depression
Hot Water Immersion Therapy for Mental Health
In 2016, it was estimated that nearly 1 billion people worldwide were affected by a mental or addictive disorder, and were associated with considerable excess mortality. Acute heat therapy sessions (e.g.
- Conditions
- Anxiety Disorders, Depression, Post-traumatic Stress Disorder, Heat
- Trial name
- WITHME (NCT04793542)
- Testing
- lower-limb hot water immersion
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Lakehead University
PTSD, Post Traumatic Stress Disorder
Massed Cognitive Processing Therapy for Combat-related PTSD
The purpose of this study is to determine if cognitive processing therapy (CPT) delivered in a massed format (MCPT) is as effective as standard delivery of CPT.
- Trial name
- NCT03808727
- Testing
- Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- VA Boston Healthcare System
Post-Traumatic Stress Disorder (PTSD), Depression
Transforming Trauma Care
This study evaluates the implementation and clinical effectiveness of the Trauma Resilience and Recovery Program (TRRP 2.0), a technology-enhanced behavioral health intervention designed for trauma center patients.
- Conditions
- Post-Traumatic Stress Disorder (PTSD), Depression, Substance Use Disorder, Traumatic Injury
- Trial name
- NCT07829510
- Testing
- Trauma Resilience and Recovery Program Portal 2.0 (TRRP 2.0)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Post-traumatic Stress Disorder
Interest of Cardiac Coherence in the Prevention of Chronic Post-traumatic Stress Disorder: Pilot Study
ThThe aim of this study is to determinate the potential benefits of a respiratory training program (cardiac coherence, CC) in patients suffering from acute stress disorder, after a potentially traumatic event.
- Trial name
- COHEPS-P (NCT04701723)
- Testing
- cardiac coherence
- Where
- Reunion
- Volunteers
- 44 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Transcranial Magnetic Stimulation, Functional Near-Infrared Spectroscopy
Treatment of Post-concussion Syndrome With TMS: Using FNIRS as a Biomarker of Response
Every year, approximately 2 million people in the United States and 280,000 in Canada experience a mild traumatic brain injury/concussion.
- Conditions
- Transcranial Magnetic Stimulation, Functional Near-Infrared Spectroscopy, Post-Concussion Syndrome, Concussion
- Trial name
- NCT04568369
- Testing
- rTMS
- Where
- Canada
- Volunteers
- 91 people
- Sponsor
- University of Calgary
Stress Disorders, Post-Traumatic
Mantram Repetition Meditation for Veterans With PTSD
The aim of this study was to determine the usefulness of a portable, meditation-based intervention called the Mantram Repetition Program (MRP) for Veterans with military-related posttraumatic stress disorder (PTSD).
- Trial name
- NCT01506323
- Testing
- Mantram Repetition Program (MRP), Present Centered Therapy (PCT)
- Where
- 2 sites in United States
- Volunteers
- 181 people
- Sponsor
- US Department of Veterans Affairs
Earthquake, Compassion Fatigue
Impact of Earthquake Trauma on Nurses' Compassion Fatigue: A Study From Kahramanmaraş, Turkey
This study investigates the impact of earthquake trauma on compassion fatigue among nurses working in emergency services following the devastating earthquakes on 6 February 2023, in Kahramanmaraş, Turkey.
- Trial name
- NCT06288880
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Kilis 7 Aralik University
PTSD - Post Traumatic Stress Disorder, Trauma-related Nightmares
Validation of an Algorithm for Predicting Awakenings Associated With Trauma-related Nightmares, Based on the Analysis of Physiological Patterns in Military and Former Military Patients Suffering From Post-traumatic Stress Disorder
The goal of this clinical trial is to validate an artificial intelligence algorithm called CAUD-PIN (CAUchemar Detection on INdividualized Parameters) to predict nightmare-related awakenings in military personnel and veterans…
- Trial name
- CAUD-PIN (NCT07851480)
- Testing
- CAUD-PIN (CAUchemar Detection on INdividualized Parameters) - AI-based predictive algorithm forTrauma-related nightmare awakenings
- Where
- 3 sites in France
- Volunteers
- 27 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Post-traumatic Stress Disorder
Using Reconsolidation Blockade to Treat Trauma Related Disorders After Paris Attacks: an Effectiveness Study
The purpose of this study is: (1) to examine the effectiveness of reconsolidation blockade as a treatment for trauma-related disorders, (2) to evaluate the feasibility of implementing this new treatment on a large scale in a…
- Trial name
- PARIS-MEM (NCT02789982)
- Testing
- β-adrenergic blocker propranolol, Treatment as usual
- Where
- 20 sites in France, Martinique
- Volunteers
- 364 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Borderline Personality Disorder, Stress Disorders, Post-Traumatic
Narrative Exposure Therapy in Women With Borderline Personality Disorder and Posttraumatic Stress Disorder
Narrative Exposure Therapy (NET) is an evidence-based trauma-focussed treatment, suitable for survivors of prolonged and repeated exposure to traumatic stress and childhood adversity.
- Trial name
- NCT02517723
- Testing
- Narrative Exposure Therapy, Dialectical Behavior Therapy, Standard Inpatient Care
- Where
- Germany
- Volunteers
- 67 people
- Sponsor
- Evangelisches Krankenhaus Bielefeld gGmbH
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