Clinical trials: Trauma and Stress-related Disorders
Posttraumatic Stress Disorder
Emotional Working Memory Training for Veterans With PTSD Symptoms
PTSD is characterized by recurrent intrusion of trauma-related memories and images that cause significant distress and impairment to the affected individuals.
- Trial name
- NCT02766296
- Testing
- Active Emotional Working Memory Training, Control Working Memory Training
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Milwaukee VA Medical Center
Posttraumatic Stress Disorder, Covid19
Efficacy of TBCT, MBHP and PPT for PTSD During the Covid-19 Pandemics
The psychotherapies to be assessed in the present study, delivered on-line, are: trial-based cognitive therapy (TBCT), mindfulness-based health promotion (MBHP), and positive psychotherapy (PPT).
- Trial name
- NCT04852770
- Testing
- Trial-Based Cognitive Therapy, Mindfulness-Based Health Promotion, Positive psychotherapy
- Where
- 3 sites in Brazil
- Volunteers
- 135 people
- Sponsor
- Fundação Bahiana de Infectologia
Stress Disorders, Post-Traumatic
Fluoxetine vs EMDR to Treat Post-Traumatic Stress Disorder (PTSD)
The purpose of this study is to compare two treatments for post-traumatic stress disorder (PTSD): fluoxetine (an antidepressant) and Eye Movement Desensitization and Reprocessing (EMDR, a psychological treatment in which the…
- Trial name
- NCT00000379
- Testing
- Fluoxetine, EMDR
- Where
- United States
- Sponsor
- Boston University
Anxiety Disorders, Depressive Disorders
Role of the Stress in the Development of the Metabolic Syndrome
The purpose of this study is determine the incidence of metabolic syndrome (MetS) in people of high risk, of 40 or more years and attended in the Primary Care.
- Conditions
- Anxiety Disorders, Depressive Disorders, Metabolic Syndrome, Stress Disorders
- Trial name
- STREX (NCT01538082)
- Where
- Spain
- Volunteers
- 738 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Post-Traumatic Stress Disorder
Trauma-Informed Goal Management Training for Individuals With Post-traumatic Stress Disorder (PTSD)
Goal Management Training (GMT) is a program designed to help improve cognitive functioning. For this study, researchers have worked closely with the developers of this program to create a modified version called Trauma-Informed…
- Trial name
- TI-GMT (NCT06354361)
- Testing
- Trauma-Informed Goal Management Training (TI-GMT)
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- McMaster University
Posttraumatic Stress Disorder (PTSD), Anxiety
Mindful Self-Compassion to Address PTSD and Substance Use in Unhoused Women
Trauma exposure, posttraumatic stress disorder (PTSD), and substance use disorder (SUD) present major threats to public health. PTSD and SUD are major correlates of disability, often resulting in severe social and occupational…
- Conditions
- Posttraumatic Stress Disorder (PTSD), Anxiety, Depression - Major Depressive Disorder
- Trial name
- MSC for PTSD (NCT06646692)
- Testing
- Mindful Self Compassion, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- University of California, Los Angeles
Anxiety, Trauma
Intergenerational Transmission of Terror
Our aim is examine avenues by which mothers can transmit their trauma to their children.
- Conditions
- Anxiety, Trauma, Stress Disorders
- Trial name
- NCT00320437
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
PTSD, Posttraumatic Stress Disorder
Characterization of the Use of Antipsychotics in Posttraumatic Stress Disorder During the Past Decade
The main purpose is to show the percentage of patients taking antipsychotics with PTSD by looking at approximately ten year's worth of data from 1994 through 2004.
- Trial name
- NCT00233467
- Where
- United States
- Sponsor
- Tuscaloosa Research & Education Advancement Corporation
Blast Injuries, Traumatic Brain Injury
The Effects of Explosive Blast as Compared to Post-Traumatic Stress Disorder on Brain Function and Structure
Brain injury from explosive blast is a prominent feature of contemporary combat. Although protective armor and effective acute medical intervention allows soldiers to survive blast events, a growing number of veterans will have…
- Conditions
- Blast Injuries, Traumatic Brain Injury, Post-Traumatic Stress Disorders
- Trial name
- NCT00631436
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Center for Veterans Research and Education
Post-Traumatic Stress Disorder
Safety and Efficacy of NYX-783 in Subjects With Post-Traumatic Stress Disorder
To evaluate the safety, tolerability, and response profile of NYX-783 in a Post-Traumatic Stress Disorder population.
- Trial name
- NCT04044664
- Testing
- NYX-783
- Where
- 37 sites in United States
- Volunteers
- 160 people
- Sponsor
- Aptinyx
Post-traumatic Stress Disorder
Program for Alleviating and Resolving Trauma and Stress 2
This pilot RCT will test the preliminary efficacy of an intensive group model of Internal Family Systems (IFS) called the Program for Alleviating and Resolving Trauma and Stress (PARTS) compared with a Nature-Based Stress…
- Trial name
- PARTS2 (NCT05095428)
- Testing
- PARTS Program, NBSR-T Program
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Post Traumatic Stress Disorder, Avalanche, Landslide, or Mudslide
Posttraumatic Stress Disorder and Quality of Life of Avalanche Survivors From 2014 to 2018, Based on the French North Alpine Avalanche Register
The aim of this study is to identify if an avalanche accident has a psychological impact on avalanche victims. The investigators hypothesize that being exposed to an avalanche could generate enough stress to develop posttraumatic…
- Conditions
- Post Traumatic Stress Disorder, Avalanche, Landslide, or Mudslide, Quality of Life
- Trial name
- ESPTAvalanche (NCT03936738)
- Where
- France
- Volunteers
- 107 people
- Sponsor
- University Hospital, Grenoble
Hearing Impairment, Hearing Aid Fitting
Blast Exposed Veterans With Auditory Complaints
The purpose of this study is to study blast-exposed Veterans who report hearing handicap but show normal or near normal results on standard audiometric testing.
- Trial name
- NCT02122458
- Testing
- mild-gain hearing aids with high-frequency emphasis over 6-months
- Where
- 3 sites in United States
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
PTSD
Morning Light Treatment at Home to Reduce PTSD Symptoms
There is evidence that some of the circadian photoreceptors, the intrinsically photosensitive retinal ganglion cells (ipRGCs), project directly to the amygdala, an area of the brain implicated in PTSD.
- Trial name
- NCT03513848
- Testing
- Retimer
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Rush University Medical Center
PTSD
Home-Delivered Attention Control Treatment for Post Traumatic Stress Disorder (PTSD)
The aim of the study is to explore the efficacy of home-delivered Attention Control Training (ACT) for Posttraumatic Stress Disorder (PTSD).
- Trial name
- NCT04228133
- Testing
- Attention Control Training (ACT), Attention Bias Modification (ABM)
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel Aviv University
Post Traumatic Stress Disorder
Noninvasive Brain Stimulation Combined With Written Exposure Therapy for PTSD in Military Personnel With TBI
In this study, the investigators are evaluating whether transcranial direct current stimulation (tDCS), a brain stimulation technique, can be combined with Written Exposure Therapy (WET), a standard talk therapy for posttraumatic…
- Trial name
- NCT07715799
- Testing
- Transcranial Direct Current Stimulator, Written Exposure Therapy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Posttraumatic Stress Disorder
Mind-Body Skills Groups for the Treatment of War-Related Trauma in Adults in Gaza
The objective of this study is to determine whether participation in a mind-body skills program by war-traumatized adults in Gaza will result in improvement of posttraumatic stress symptoms and depression, and will increase…
- Trial name
- NCT01595464
- Testing
- Mind-Body Skills Groups
- Where
- Israel
- Volunteers
- 148 people
- Sponsor
- The Center for Mind-Body Medicine
PTSD
A 40-week Study to Evaluate TNX-102 SL 5.6 mg Taken Daily at Bedtime in Patients With PTSD
Evaluate the long-term safety of TNX-102 SL 5.6 mg taken daily at bedtime over an additional 40 weeks in patients with PTSD who have participated in a double-blind lead-in study and completed an initial 12-week open-label…
- Trial name
- P306 (NCT03508700)
- Testing
- TNX-102 SL 5.6 mg
- Where
- 16 sites in United States
- Volunteers
- 93 people
- Sponsor
- Tonix Pharmaceuticals, Inc.
Psychological Disorder, Anxiety Disorders
Examining Change Mechanisms in Psychotherapy
This research project seeks to acquire a deeper understanding of the complex influences of common factors and specific ingredients in psychotherapy.
- Conditions
- Psychological Disorder, Anxiety Disorders, Depression, Eating Disorder
- Trial name
- CAMP (NCT03503981)
- Testing
- Psychotherapy
- Where
- Norway
- Volunteers
- 520 people
- Sponsor
- Modum Bad
Perinatal Mental Health, Reproductive Behavior
Women's Reproductive Choices and Mental Health During Pregnancy and After Birth in Wartime Ukraine
The goal of this observational study is to learn how war affects reproductive decisions and perinatal mental health in Ukrainian women.
- Conditions
- Perinatal Mental Health, Reproductive Behavior, Women, Cohort Studies
- Trial name
- NCT07551934
- Testing
- Psychological Assessment, Routine Clinical Data Collection
- Where
- Ukraine
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Taras Shevchenko National University of Kyiv
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