Clinical trials: Trauma and Stressor Related Disorder
Post Traumatic Stress Disorder
Effect of TMS on PTSD Biomarkers
The study will (1) assess feasibility of a TMS treatment in an underserved population; (2) determine if this TMS treatment protocol improves PTSD symptoms and biological markers of PTSD such as brain functioning and startle…
- Trial name
- NCT04563078
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Emory University
Anxiety Disorders, Depression
Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol
The proposed project aims to test the cognitive and neural effects of a cognitive training in a sample of individuals seeking treatment for anxiety, depression, or traumatic stress symptoms.
- Conditions
- Anxiety Disorders, Depression, Posttraumatic Stress Disorder
- Trial name
- NCT04912089
- Testing
- COGENT
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of California, San Diego
PTSD
TMS for Veterans Attending a 2-week Intensive Outpatient Program for PTSD
The goal of this study is to determine whether complementing regular intensive PTSD treatment with intermittent theta burst stimulation (iTBS) applied to the right dorsolateral prefrontal cortex (DLPFC) can improve treatment…
- Trial name
- NCT06271733
- Testing
- TMS
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Rush University Medical Center
Post-Traumatic Stress Disorder, Alcohol Use Disorder
Resolving Psychological Stress
The investigators have developed a mobile app called Resolving Psychological Stress (REPS) to help alleviate symptoms of PTSD. The app will administer threat-related attention bias modification to individuals who have both a…
- Trial name
- RePS (NCT03996876)
- Testing
- RePS (Resolving Psychological Stress) - Threat ABM Training, RePS (Resolving Psychological Stress) - Neutral Attention Training
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of California, San Francisco
Posttraumatic Stress Disorder
Evaluating a Novel Working Memory Training Program to Decrease Symptoms of PTSD
The study is designed to evaluate the effect of a novel computer training program on PTSD.
- Trial name
- NCT02139137
- Testing
- Computerized Cognitive Training - active
- Volunteers
- 47 people
- Sponsor
- Rick Gulizia
Post-traumatic Stress Disorder, Insomnia
Pimavanserin for Insomnia In Veterans With Posttraumatic Stress Disorder
This preliminary, open-label study assesses the feasibility of 34mg at bedtime for 6 weeks in Veterans with Posttraumatic Stress Disorder and insomnia.
- Trial name
- PIP (NCT04188392)
- Testing
- Pimavanserin
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Baylor College of Medicine
Parenting Behaviors and PTSD Symptoms
Parenting Strength At Home- Parents Pilot
The overall goal of this work is to adapt, refine, and conduct an open trial of a parent-training intervention for Veterans with posttraumatic stress disorder (PTSD) symptoms using feedback from Veterans, VA clinicians, and…
- Trial name
- PSAH (NCT03403153)
- Testing
- SAHP
- Where
- 3 sites in United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
PTSD
Pilot Trial of Mobile Mantram Delivery
Mantram Repetition Program (MRP) is a meditation practice that involves silent repetition of a spiritual word, one-pointed attention, and slowing down. It has been shown to help reduce PTSD symptoms among Veterans.
- Trial name
- mMRP (NCT05998967)
- Testing
- Mobile Mantram Repetition Program
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Neuroses
An Adjunctive Family Intervention for Individual Posttraumatic Stress Disorder Treatment
This study aims to test a brief family intervention (the BFI) to enhance individually-delivered PTSD treatment for Veterans.
- Trial name
- NCT02956434
- Testing
- Brief Family Intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- VA Office of Research and Development
Depression, PTSD
DDBT Adapted Problem Solving Treatment for Primary Care
Evidence-based psychosocial interventions are rarely used in part because of their design complexity. Although many implementation frameworks do address the importance of EBPI characteristics, adapting and modifying EBPIs to…
- Trial name
- PST-NA (NCT03514394)
- Testing
- Usual Care, Modified Behavioral Activation (Task Sharing)
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Washington
Stress Disorders, Post-Traumatic
Breathing Meditation Intervention for Post Traumatic Stress Disorder
Post traumatic stress disorder (PTSD) is a condition that develops as a result of exposure to a traumatic event. The purpose of this study is to determine whether a breathing meditation technique (Sudarshan Kriya Yoga; SKY)…
- Trial name
- NCT02366403
- Testing
- SKY meditation, CPT-C
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder, Depression
Loving-Kindness Meditation for PTSD
This randomized controlled trial will assess whether a novel complementary and alternative medicines (CAM) intervention, Loving-kindness Meditation (LKM), is not meaningfully inferior to another group-based PTSD treatment …
- Trial name
- NCT01962714
- Testing
- Loving-Kindness Meditation, Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- VA Office of Research and Development
Depressive Disorder, Major, Post Traumatic Stress Disorder
A Randomized Control Trial Treating Depression With Yoga and Coherent Breathing Versus Walking in Veterans
The proposed study addresses a gap regarding the need for effective Major Depressive Disorder (MDD) treatments and the 40% of individuals treated with antidepressant medications that do not achieve full remission.
- Trial name
- NCT03489122
- Testing
- yoga, walking
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Group Based Exposure Therapy for Combat-Related PTSD
The purpose of this randomized controlled trial is to determine if Group Based Exposure Therapy (GBET) is more effective than treatment as usual in reducing the symptoms of war-related Posttraumatic Stress Disorder (PTSD).
- Trial name
- NCT00535223
- Testing
- Group Based Exposure Therapy, Present Centered Group Therapy
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- US Department of Veterans Affairs
Chronic Posttraumatic Stress Disorder
Enhancing Extinction Learning in Post Traumatic Stress Disorder (PTSD)
Posttraumatic stress disorder (PTSD) is a condition that involves intense memories of a traumatic event and intense, persistent feelings of anxiety.
- Trial name
- HELP (NCT01188694)
- Testing
- Psychotherapy plus Methylene Blue, USP, Delayed Psychotherapy
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- University of Washington
Post Traumatic Stress Disorder, Depression
Does an Occupational Therapy Program Enhance Mental Health Outcomes for Veterans Who Scuba Dive
The purpose of the study is to investigate whether an occupational therapy program could enhance mental health outcomes for veterans who SCUBA dive.
- Conditions
- Post Traumatic Stress Disorder, Depression, Anxiety, Stress, Psychological
- Trial name
- NCT03928392
- Testing
- SCUBA with Occupational Therapy (OT), Self-Contained Underwater Breathing Apparatus (SCUBA) without OT
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Loma Linda University
PTSD
Safety Study of Riluzole to Treat Post-traumatic Stress Disorder (PTSD)
The purpose of this study is to determine whether Riluzole is effective in the augmentation treatment of post-traumatic stress disorder (PTSD) that is experienced by Active Duty military service members and Operation Enduring…
- Trial name
- NCT02155829
- Testing
- Riluzole
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- Uniformed Services University of the Health Sciences
Posttraumatic Stress Disorder
An Open Label Pilot Study of Adjunctive Asenapine for the Treatment of Posttraumatic Stress Disorder
This is an open-label pilot study of adjunctive asenapine for the treatment of Posttraumatic Stress Disorder (PTSD) in veterans who have not fully remitted to an adequate trial of standard antidepressant treatment.
- Trial name
- NCT01587118
- Testing
- Adjunctive asenapine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Lori Davis, MD
Chronic Pain, Traumatic Brain Injury
Establishing Efficacy of a Functional-Restoration Based CAM Pain Management Program in Post-9/11 Veterans
This is a research study of an interdisciplinary pain management program for U.S. military veterans who served during the post-9/11 combat eras (e.g., Operations Iraqi Freedom [OIF], Enduring Freedom [OEF], New Dawn [OND])…
- Conditions
- Chronic Pain, Traumatic Brain Injury, Posttraumatic Stress Disorder, Depression
- Trial name
- NCT02657317
- Testing
- FORT-A, VA Treatment as Usual
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Posttraumatic Stress Disorder
Compassion Meditation for PTSD
The goal of this project is to refine an existing compassion meditation protocol for individuals with posttraumatic stress disorder (PTSD), to examine the safety and feasibility of this approach and to collect data to make…
- Trial name
- NCT02372396
- Testing
- Compassion Meditation (CM), Relaxation
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Veterans Medical Research Foundation