Clinical trials: Trauma to the Abdomen
Abscess, Intra-Abdominal, Abdominal Abscess
A Safety and Tolerability Study of Doripenem Compared With Meropenem in Children Hospitalized With Complicated Intra-abdominal Infections
The purpose of the study is to evaluate the safety and tolerability of doripenem compared with meropenem in children hospitalized with complicated intra-abdominal infections.
- Conditions
- Abscess, Intra-Abdominal, Abdominal Abscess, Abdomen, Acute, Abdominal Pain
- Trial name
- NCT01110382
- Testing
- Doripenem, Meropenem, Amoxicillin/clavulanate potassium
- Where
- 19 sites in United States, Argentina and 6 more
- Volunteers
- 41 people
- Sponsor
- Janssen Research & Development, LLC
Abdominal Injuries, Physical Abuse
Effectiveness of Contrast-Enhanced Ultrasound
The purpose of the study is to generate pilot data describing test characteristics of contrast enhanced ultrasound in young children with concern for abdominal trauma.
- Conditions
- Abdominal Injuries, Physical Abuse, Accidental Fall, Motor Vehicle Injury
- Trial name
- NCT03473249
- Testing
- Contrast-Enhanced Ultrasound using Lumason
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Abdominal Trauma
BEFAST (Bubble-Enhanced FAST) for the Evaluation of Solid Organ Injury
The Focused Assessment with Sonography for Trauma (FAST) exam is widely used and accepted as part of advanced trauma life support (ATLS) protocol, but its low sensitivity for identifying solid organ injury in the absence of…
- Trial name
- BEFAST (NCT05025449)
- Testing
- Focused Assessment with Sonography for Trauma (FAST), Bubble-Enhanced FAST (BEFAST)
- Where
- United States
- Volunteers
- 267 people
- Sponsor
- Emory University
Penetrating Abdominal Trauma
Outcomes After Laparotomy for Penetrating Abdominal Trauma
The purpose of this study is to evaluate outcomes of adult patients hospitalised due to penetrating abdominal trauma at a tertiary trauma hospital in South Africa.
- Trial name
- NCT04536818
- Testing
- Laparotomy
- Where
- South Africa
- Volunteers
- 196 people
- Sponsor
- Karolinska Institutet
Postoperative Abdominal Wounds, Wound-healing Impairments
Evaluate the Efficacy of the Treatment of Iatrogenic Subcutaneous Abdominal Wounds (ISAW) After Surgery by Application of Negative Pressure Wound Therapy (NPWT) in Comparison to Standard Conventional Wound Therapy (SCWT) of the Clinical Routine
The purpose of this study is to determine whether Negative Pressure Wound Therapy (NPWT) or Standard Conventional Wound Therapy (SCWT) are effective in the treatment of Iatrogenic Subcutaneous Abdominal Wound healing-impairments…
- Trial name
- ISAW (NCT01611207)
- Testing
- Negative Pressure Wound Therapy, Standard Wound Therapy
- Where
- 34 sites in Germany
- Volunteers
- 12 people
- Sponsor
- University of Witten/Herdecke
Abdominal Injury, Thoracic Diseases
A Post Market Study to Confirm the Safety and Performance of the Signia™ Stapling System.
The objectives of this prospective, two-arm, multicenter post-market study is to confirm safety and performance through the incidence of subjects reporting serious adverse device effects (ADEs) up to and including 30 days…
- Trial name
- NCT03515811
- Testing
- Signia™ Stapling System
- Where
- 11 sites in United States, Canada and 3 more
- Volunteers
- 136 people
- Sponsor
- Medtronic - MITG
Appendicitis, Evidence of Cholecystectomy
Point of Care 3D Ultrasound for Various Applications: A Pilot Study
Summary 1. Purpose and Objective: The purpose of this study is to test the feasibility of rapid acquisition of point of care 3D ultrasound in obtaining abdominal and/or pelvic images.
- Conditions
- Appendicitis, Evidence of Cholecystectomy, Gallstones, Pregnancy, Ectopic
- Trial name
- NCT02831556
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Duke University
Abdominal Trauma, Follow-up in Abdominal Trauma
The PseAn Study - Study Protocol
The researchers aim to study the role of contrast ultrasound in detecting post-traumatic splenic, hepatic, and renal PAs compared with the gold standard of CT with intravenous contrast at different follow-up time points, and…
- Trial name
- PseAn (NCT05627908)
- Testing
- Contrast-enhanced ultrasound
- Where
- Italy
- Volunteers
- 385 people
- Sponsor
- Niguarda Hospital
Splenic Rupture, Abdominal Injuries
Outcome After Conservative and Surgical Treatment of Splenic Injuries After Blunt Abdominal Trauma.
Retrospective study in order to investigate the outcome after conservative (with or without transcatheter arterial embolization) and surgical treatment of splenic injuries.
- Trial name
- NCT00910182
- Testing
- splenorrhaphy
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Wound
Study of DERMABOND ProPen in Closure of Colectomy Wounds
2-octylcyanoacrylate (2-OCA) has been used extensively in clinical practice in trauma, plastic surgery, orthopaedic surgery, emergency medicine and paediatrics.
- Trial name
- NCT00978133
- Testing
- Dermabond ProPen (2-octylcyanoacrylate), Skin closure with skin staples
- Where
- Singapore
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Trauma Centers/Statistics & Numerical Data, Trauma Blunt
Results of Medical and Nursing Record,Physical Examination, Blood Test and Radiological Examination of Multiple Trauma to Find the Correlation With Patient's Morality and Mobility
This study aims to analyze statistical data on physiological examination values, blood test results, and radiological findings in patients admitted to the emergency department for severe trauma.
- Conditions
- Trauma Centers/Statistics & Numerical Data, Trauma Blunt, Trauma (Including Fractures), Trauma Abdomen
- Trial name
- trauma (NCT07903727)
- Testing
- Collect results of trauma patients
- Volunteers
- 700 people
- Sponsor
- St. Martin De Porress Hospital
Pancreatic Trauma, Pancreatic Duct Injury
A Retrospective Analysis of Pancreatic Injuries and Treatment Outcomes
The goal of this observational study is to compare the presentation, treatment, and outcomes in patients suffering traumatic pancreatic injuries from blunt or penetrating trauma. The questions this study aims to answer are: 1.
- Conditions
- Pancreatic Trauma, Pancreatic Duct Injury, Pancreas Necrosis, Pancreas Cyst
- Trial name
- NCT06227871
- Testing
- Exploratory laparotomy
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Kern Medical Center
Abdominal Injuries
Hypertonic Saline Resuscitation in Trauma Patients After Hemorrhage Control
This study aimed to determine whether hypertonic saline solution is effective in the resuscitation of injured patients undergoing abdominal damage control surgery regarding early closure of the abdominal wall.
- Trial name
- CELTA (NCT02542241)
- Testing
- Sodium Chloride [3%], Sodium Chloride [0.9%]
- Where
- Colombia
- Volunteers
- 52 people
- Sponsor
- Fundacion Clinica Valle del Lili
Abdominal Trauma
Contrast Enhanced Ultrasound for Evaluation of Pediatric Abdominal Trauma
The research protocol aims to compare the utility of contrast enhanced abdominal sonography with computerized tomography in the evaluation of children with blunt abdominal trauma.
- Trial name
- NCT01763840
- Testing
- Contrast enhanced Ultrasound
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- David Mooney
Trauma (Including Fractures), Trauma Abdomen
5 Minute 'HOT' Trauma CT Rates Of Detection Study
Many injured patients receive urgent CT imaging to identify major injury. CT imaging of trauma patients is often time critical and the accurate detection of life-threatening findings on this CT is essential.
- Conditions
- Trauma (Including Fractures), Trauma Abdomen, Trauma Blunt, Trauma Centers
- Trial name
- NCT07314437
- Testing
- Education
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital Plymouth NHS Trust
Laparoscopic Surgery
Laparoscopic Splenectomy in Isolated High Grades Splenic Injuries
Background: Trauma laparoscopic splenectomy has no defined reasons. Compared trauma patient characteristics and results with laparoscopic and open splenectomies.
- Trial name
- NCT04329845
- Testing
- open splenectomy, laparoscopic splenectomy for splenic injury in trauma
- Volunteers
- 2 people
- Sponsor
- Zagazig University
Hernia Incisional, Suture, Complication
DuraMesh Laparotomy Closure Following Trauma and Emergency Surgery
The proposed project aims to evaluate the safety of DuraMesh™ suture for laparotomy closure in an emergent setting, while also providing preliminary efficacy data with regard to incisional hernia prevention.
- Trial name
- NCT04312165
- Testing
- Duramesh Laparotomy Closure, Conventional suture closure
- Where
- 2 sites in United States
- Sponsor
- Uniformed Services University of the Health Sciences
Pediatric Abdominal Trauma
Pediatric Blunt Abdominal Trauma Clinical Prediction Model
The submitted proposal is designed to reduce morbidity and mortality to injured children. Significant variability in the initial trauma assessment exists among institutions.
- Trial name
- NCT02206698
- Where
- 14 sites in United States
- Volunteers
- 2,800 people
- Sponsor
- Medical University of South Carolina
C.Surgical Procedure; Disruption of Wound, Suture
Use of Stratafix Symmetric™ to Prevent Incisional Hernia in Gastrointestinal and Abdominal Surgery
Comparing the use of Stratafix Symmetric™ sutures to standard laparotomy closure sutures.
- Trial name
- STRATA-G (NCT06063577)
- Testing
- Stratafix suture, Standard of care suture
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- West Michigan Cancer Center
Abdominal Trauma
An Analysis of Cytokine Concentration in Open Abdominal Closure of Trauma Patients
The purpose of this study is to compare the pro-inflammatory and anti-inflammatory cytokines, protein content, and white blood cell (WBC) count present in the peritoneal fluid and plasma of trauma patients who undergo one of two…
- Trial name
- NCT02728609
- Testing
- ABThera vacuum device, Blue towel: vacuum pack device
- Volunteers
- 40 people
- Sponsor
- University of Tennessee