Clinical trials: Trauma to the Abdomen
Diet, Healthy, Food
The PASTDUe Nutrition Ecosystem Project (PASTDUe)
This is a research study to determine if a particular method of providing nutrition improves the clinical outcomes of patients in the intensive care unit (ICU) who have undergone abdominal surgery and would require nutrition…
- Conditions
- Diet, Healthy, Food, Nutrition, Intensive Care
- Trial name
- PASTDUe (NCT05127109)
- Testing
- Nutrition Ecosystem pathway, Comparator
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Duke University
Trauma to the Abdomen
Enteral Feeding in the Post-Injury Open Abdomen
The purpose of this study is to determine if Enteral Feeding (EN) in patients with a traumatic bowel injury requiring an open abdomen impacts outcomes.
- Trial name
- NCT01853735
- Where
- United States
- Volunteers
- 515 people
- Sponsor
- Denver Health and Hospital Authority
Laparoscopic Hysterectomy, Abdominal Hysterectomy
Pentraxin-3 in Hysterectomy Patients
Comparison of the Tissue Trauma Markers Following Total Laparoscopic Hysterectomy vs Total Abdominal Hysterectomy
- Trial name
- NCT04366375
- Testing
- PTX-3
- Volunteers
- 40 people
- Sponsor
- Muğla Sıtkı Koçman University
Surgical Site Infection, Surgical Wound Infection
ROSSINI 2 - Reduction of Surgical Site Infection Using Several Novel Interventions
ROSSINI 2 is a phase III, multi-arm, multi-stage (MAMS) pragmatic, blinded (patient and outcome assessor), multicentre, randomised controlled trial (RCT) with an internal pilot, to evaluate the use of several in-theatre…
- Conditions
- Surgical Site Infection, Surgical Wound Infection, Surgery--Complications, Surgery
- Trial name
- ROSSINI 2 (NCT03838575)
- Testing
- 2% alcoholic chlorhexidine skin prep (SKIN PREP), Iodophor Antimicrobial Incise Drapes (DRAPE), Gentamicin-impregnated implants/ sponges (SPONGE)
- Where
- 2 sites in United Kingdom
- Volunteers
- 6,610 people
- Sponsor
- University of Birmingham
Abdominal Injuries, Wounds and Injuries
Predictors of In-Hospital Mortality in Severe Abdominal Trauma
Severe abdominal trauma is a leading cause of early death from bleeding and of later death from sepsis and organ failure. Clinicians use scoring systems to estimate the risk of dying, but most of these scores were developed and…
- Conditions
- Abdominal Injuries, Wounds and Injuries, Wounds, Nonpenetrating, Wounds, Penetrating
- Trial name
- NCT07843628
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- Minia University
Abdomenal Wound Trauma
Non-Comparative Study of Open Abdomen That Require the Use of Negative Pressure Wound Therapy (NPWT) for Temporary Abdominal Closure
A study in which subjects with a Grade 1 or Grade 2 open abdomen that require the use of NPWT for temporary abdominal closure. Subjects will use the NPWT system for up to 14 days, with a 21 day post study initiation follow-up…
- Trial name
- NCT03431220
- Testing
- RENASYS® TOUCH Negative Pressure Wound Therapy (NPWT) Device
- Where
- United States
- Sponsor
- Smith & Nephew, Inc.
Abdominal Injuries, Alcohol Intoxication
Alcohol, Psychoactive Drugs, Analgesics and Evaluation in Penetrating Abdominal Trauma
This prospective observational study aims to evaluate whether alcohol consumption, psychoactive drug use, or prior administration of analgesics affects the clinical evaluation and surgical decision-making process in patients with…
- Conditions
- Abdominal Injuries, Alcohol Intoxication, Substance-related Disorders, Penetrating Abdominal Trauma
- Trial name
- DIRECT (NCT07330349)
- Testing
- Alcohol consumption, Psychoactive substance use, Analgesic administration
- Where
- 2 sites in Colombia
- Volunteers
- 363 people
- Sponsor
- Fundacion Clinica Valle del Lili
Hernia, Ventral Hernia
A Study of Fibrin Sealant Plus Silver Microparticles to Prevent Incisional Hernias Following Abdominal Surgery
Incisional hernias are a frequent consequence of abdominal surgery. Current clinical efforts are primarily focused on improving repair materials and surgical techniques to correct these hernias instead of the optimal solution…
- Conditions
- Hernia, Ventral Hernia, Abdominal Hernia
- Trial name
- HiP_1 (NCT02584153)
- Testing
- Fibrin Sealant, Silver Microparticles
- Sponsor
- Hobart Harris
Opioid Consumption, Multimodal Analgesia
Magnesium Sulfate in Children Undergoing Laparoscopic Appendectomy
Magnesium sulfate is one of the most commonly used co-analgetics. Its antinociceptive effect is related to antagonizing NMDA (N-methyl-D-aspartate) receptors of the nervous system, has an anti-inflammatory effect by reducing the…
- Conditions
- Opioid Consumption, Multimodal Analgesia, Acute Appendicitis, Complication of Treatment
- Trial name
- NCT06563349
- Testing
- Intravenous magnesium sulfate, Normal saline infusion
- Where
- Poland
- Volunteers
- 188 people
- Sponsor
- Medical University of Warsaw
Abdominal Injury
Contrast-Enhanced Ultrasound in the Evaluation of Abdominal Injuries in Children
This study proposes to evaluate the accuracy of contrast-enhanced ultrasound (CEUS) in diagnosing abdominal solid organ injuries in pediatric patients. 146 subjects will be enrolled across approximately 8 sites in the US.
- Trial name
- NCT03147690
- Testing
- Lumason
- Where
- 8 sites in United States
- Volunteers
- 74 people
- Sponsor
- David Mooney
Transplant;Failure,Kidney, Transplant; Failure, Liver
Abdominal Wall Transplant
The purpose of this protocol is to determine the safety and efficacy of abdominal wall transplantation as a treatment for the reconstruction of abdominal wall defects.
- Conditions
- Transplant;Failure,Kidney, Transplant; Failure, Liver, Transplant; Failure, Bowel, Abdominal Wall Defect
- Trial name
- NCT03310905
- Testing
- Abdominal Wall Transplant with another solid organ transplant, Abdominal Wall Transplant alone
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Duke University
Abdominal Injuries, Thoracic Injuries
Robot-based Tele-echography II - A Comparative Study
The aim of this clinical trial is to evaluate the concordance of diagnosis of injuries in thoracoabdominal trauma using two different echographic methods.
- Conditions
- Abdominal Injuries, Thoracic Injuries, High Energy Trauma
- Trial name
- NCT00295438
- Testing
- Robot-Based Tele-Echography (TER), ultrasound method FAST
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Grenoble
Blunt Abdominal Trauma
Pelvic CT Imaging in Blunt Abdominal Trauma
Abdominopelvic CT (CTap) utilization rose significantly in blunt trauma patients over the last decade. However, the observed increases failed to reduce mortality or missed injury rates.
- Trial name
- NCT01828749
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- Wake Forest University Health Sciences
Abdominal Injury, Thoracic Injury
Outcome of Patients With Thoraco-abdominal Injury and Stress-induced Hyperglycemia or Diabetic Hyperglycemia
This study aimed to measure the effects of SIH and DH on the mortality outcomes of the adult patients with moderate to severe thoracoabdominal injury
- Conditions
- Abdominal Injury, Thoracic Injury, Hyperglycemia, Hyperglycemia Stress
- Trial name
- NCT04058015
- Testing
- Stress-induced hyperglycemia, Diabetic hyperglycemia, Diabetic normoglycemia
- Where
- Taiwan
- Volunteers
- 802 people
- Sponsor
- Chang Gung Memorial Hospital
Fistula, Abdominal Injury
Pilot Study Evaluating the Safety and Efficacy of a Patient-Specific Enteroatmospheric Fistula Isolation and Management Device Independent of Negative Pressure Wound Therapy
This study aims to assess the efficacy of a custom fitted device designed to isolate enteroatmospheric fistulas effluent independent of negative pressure wound therapy and to evaluate the effects on the device related to dressing…
- Conditions
- Fistula, Abdominal Injury, Negative Pressure Wound Therapy
- Trial name
- NCT04978090
- Testing
- 3D printed EAF management device
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Andrew Bernard
Hernia, Ventral, Hernia Incisional
Renal- and Pulmonary Function in Relation to Abdominal Hypertension After Abdominal Reconstruction
An incisional hernia is technically challenging to operate and is the most frequent long-term complication after open surgery, resulting in impaired quality of life and reduced physical ability.
- Conditions
- Hernia, Ventral, Hernia Incisional, Acute Kidney Injury, Restrictive Lung Disease
- Trial name
- REPARE (NCT04143776)
- Testing
- Abdominal reconstruction
- Where
- Denmark
- Sponsor
- Bispebjerg Hospital
Abdominal Neoplasm, Abdominal Injury
Pediatric Intravenous Contrast-Enhanced Ultrasound(CEUS) in China
The goal of this clinical trial is to evaluate the application of intravenous contrast-enhanced ultrasound examination in children with intra-abdominal diseases that require clear diagnoses.
- Conditions
- Abdominal Neoplasm, Abdominal Injury, Ascites
- Trial name
- CEUS (NCT07113808)
- Testing
- contrast-enhanced ultrasound examination, SonoVue®
- Where
- China
- Volunteers
- 108 people
- Sponsor
- The Children's Hospital of Zhejiang University School of Medicine
Abdominal Surgery, Colon Surgery
D-PLEX 310: Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection
Subjects who are planned to undergo an abdominal (colon) surgery and who will meet the study entry criteria will be randomly divided into 2 groups: for half D-PLEX will be administered concomitantly with the standard of care…
- Conditions
- Abdominal Surgery, Colon Surgery, Post-Op Infection
- Trial name
- NCT03633123
- Testing
- D-PLEX, Standard of Care (SoC)
- Where
- 8 sites in Israel
- Volunteers
- 202 people
- Sponsor
- PolyPid Ltd.
Aneurysm Aortic
Evaluation of the Efficacy of Ischemic Preconditioning to Protect Against Acute Kidney Injury After Open Surgery for Juxtarenal Abdominal Aortic Aneurysm
Juxta-renal abdominal aortic aneurysms (AAA) are challenging to treat with standard endovascular techniques (EVAR) due to their proximity to the renal arteries.
- Trial name
- EPAKI (NCT07441564)
- Testing
- patients with aortic clamping with preconditioning, patients with aortic clamping without preconditioning
- Where
- 7 sites in France
- Volunteers
- 206 people
- Sponsor
- University Hospital, Rouen
Abdominal Injuries
Utility of Abdominal Ultrasound in the Evaluation of Children With Blunt Trauma
The major goal of this project is to conduct a randomized controlled trial studying an initial evaluation strategy with abdominal ultrasound versus a strategy without abdominal ultrasound for the evaluation of children with blunt…
- Trial name
- NCT01540318
- Testing
- Abdominal Ultrasound (FAST examination)
- Where
- United States
- Volunteers
- 925 people
- Sponsor
- University of California, Davis