Clinical trials: Trauma-related Stressor
Prolonged Grief Disorder
Psilocybin for Prolonged Grief Disorder
The primary purpose of this study is to explore the feasibility of conducting a clinical trial on the effects of psilocybin for individuals with prolonged grief disorder (PGD).
- Trial name
- NCT06724289
- Testing
- Psilocybin 25 mg, Functional Magnetic Resonance Imaging (fMRI)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Prolonged Grief Disorder, Suicidality
Prolonged Grief and Suicide Among Veterans
The primary research question in this study will ask, among those receiving outpatient mental health services (MHS) at the Eastern Colorado Healthcare System (ECHCS)/Denver Veterans Affairs Medical Center (VAMC), how many suffer…
- Trial name
- NCT01247025
- Testing
- No intervention
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Lower Urinary Tract Symptoms, Adjustment Disorders
Lower Urinary Tract Symptoms in Women and Adjustment Disorder
Our hypothesis that the prevalence of AD in uro-gynecologic patients with LUTS who are seeking medical help for their condition is higher than that of the general population (indicated by high scores at the ADNM-20; score above…
- Trial name
- LUTS and AD (NCT03444740)
- Testing
- ICIQ-FLUTS, ADMN-20
- Volunteers
- 100 people
- Sponsor
- Basel Women's University Hospital
Post Traumatic Stress Disorder, Insomnia
RESILIENT - An Online Multidimensional Treatment to Promote Resilience After a Disaster: Randomized Controlled Trial Protocol
Background. The wildfires on May 1, 2016 in Fort McMurray, Alberta (Canada), destroyed approximately 2,400 homes and buildings and led to massive displacement of approximately 88,000 people.
- Conditions
- Post Traumatic Stress Disorder, Insomnia, Depression
- Trial name
- RESILIENT (NCT04808713)
- Testing
- Treatment
- Where
- Canada
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Laval University
Post-Traumatic Stress Disorder
tDCS Plus Virtual Reality for PTSD
This study tests the efficacy of combining non-invasive brain stimulation, called transcranial direct current stimulation (tDCS), with virtual reality exposure as a treatment for Veterans with chronic posttraumatic stress…
- Trial name
- TAVRE (NCT03372460)
- Testing
- Active stimulation, Virtual Reality (VR)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- VA Office of Research and Development
Aggression, Anger
Group CBT for Aggression in Veterans
Posttraumatic stress disorder (PTSD) robustly predicts anger and aggression, and U.S. Iraq/Afghanistan-era combat Veterans report that treatment for anger and aggression is among their top priorities.
- Conditions
- Aggression, Anger, Posttraumatic Stress Disorder
- Trial name
- CBT-A (NCT02233517)
- Testing
- Cognitive Behavioral Therapy, Present Centered Therapy
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Rapamycin as a Means of Interference With Reconsolidation of Posttraumatic Stress Disorder-related Traumatic Memory
The purpose of the proposed study is to determine if pairing reactivation of a traumatic memory with a single administration of Rapamycin (e.g., Sirolimus) in men with combat-related Posttraumatic Stress Disorder leads to a…
- Trial name
- NCT01449955
- Testing
- Rapamycin
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Texas Southwestern Medical Center
Fibromyalgia, Psychological Trauma
Prevalence of the Traumatic Events in Women With Fibromyalgia
Suffering a traumatic event is a potential risk factor for developing Posttraumatic Stress Disorder (PTSD) with or without comorbidities with other pathologies that can become chronic with time, including fibromyalgia.
- Conditions
- Fibromyalgia, Psychological Trauma, Pain, Anxiety
- Trial name
- NCT04476316
- Where
- Spain
- Volunteers
- 88 people
- Sponsor
- Parc de Salut Mar
Anxiety, Mood Disorders
Assisted Animal Therapy: ReAnimal
Assisted animal therapy (AAT) is getting more and more used worldwide, in such areas as gerontology, psychiatry, or oncology. It is a complementary therapy, and benefits for patients are various, including decrease of anxiety.
- Conditions
- Anxiety, Mood Disorders, Post Traumatic Stress Disorder
- Trial name
- ReAnimal (NCT03898843)
- Testing
- Animal assisted therapy, Nasal swab sampling, STAI-Y and POMS Questionnaires
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Hospices Civils de Lyon
Alcohol Use Disorder, Depression
Project VALOR: Veteran Stress and Wellbeing
This study will examine the efficacy of an internet-based brief intervention designed to reduce risky behavior veterans as the move into their second year post-Army.
- Trial name
- NCT06095817
- Testing
- Internet Delivered Brief Intervention (IDBI)
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cornell University
Post Traumatic Stress Disorder
Cognitive-Behavioral Conjoint Therapy (CBCT) Project
Untreated posttraumatic stress disorder (PTSD) is a costly condition associated with impairment in functioning across a host of psychosocial domains including occupational and academic functioning, marital and family functioning…
- Trial name
- CBCT (NCT02720016)
- Testing
- CBCT-Home Based (CBCT-HB), CBCT-Office Based (CBCT-OB), PTSD Family Education (PFE)
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- VA Office of Research and Development
Mild Traumatic Brain Injury, Posttraumatic Stress Disorder
Improving Cognitive Rehabilitation Outcomes
Posttraumatic stress disorder (PTSD) and mild TBI (mTBI) frequently co-occur in post-9/11 Veterans, and together are associated with worse cognitive performance, mental health, everyday functioning, community integration, quality…
- Trial name
- NCT07055633
- Testing
- CCT+MBLT, CCT+ION
- Where
- 2 sites in United States
- Volunteers
- 144 people
- Sponsor
- VA Office of Research and Development
PTSD - Post Traumatic Stress Disorder
Evaluating Evidenced Based Options for PTSD Treatment
This study will look at: How practical it is to offer another round of proven therapy. How effective different therapy options are for people who didn't respond to the first treatment.
- Trial name
- NCT06733376
- Testing
- Cognitive Processing Therapy, Prolonged Exposure, Skills Training for Affective and Interpersonal Regulation
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Rush University Medical Center
PTSD, Firearm Injury
Project Safe Guard-Trauma
The goal of this randomized controlled trial is to determine if a counseling intervention, Project Safe Guard-Trauma (PSG-T), increases secure firearm storage practices in adults who screen positive for posttraumatic stress…
- Conditions
- PTSD, Firearm Injury, Suicide Prevention, Firearm Safety
- Trial name
- PSG-T (NCT06876740)
- Testing
- Project Safe Guard - Trauma, Project Safe Guard
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- University of Colorado, Denver
Alcohol Use Disorder, Trauma, Psychological
Adverse Childhood Experiences in Alcohol Use Disorder
Adverse childhood experiences (ACE) and their relation to the development of an alcohol use disorder (AUD) will be measured with functional magnetic resonance imaging (fMRI).
- Trial name
- NCT05048758
- Testing
- No intervention
- Where
- Germany
- Volunteers
- 43 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Post-traumatic Stress Disorder
An Advanced Digital Phenotype System Among People Suffering From Post-traumatic Stress Disorder
Psychiatric diagnosis is based mainly on questioning the patient and subjective impression rather than a quantitative assessment.
- Trial name
- NCT03788278
- Testing
- BioBeat
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nadav Goldental
Depression, Anxiety
Efficacy of a Multi-level School Intervention for LGBTQ Youth
Efficacy of a Multi-level School Intervention for LGBTQ Youth
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior
- Trial name
- NCT05541406
- Testing
- Proud & Empowered, Control Group
- Where
- 23 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Acute Traumatic Stress Disorders, Post-Traumatic Stress Disorders
Evaluation of Stress Disorders
The purpose of this study is to examine the short-term consequences of trauma and to determine the effectiveness of the drug sertraline in preventing and treating post-traumatic stress disorder (PTSD) and acute stress disorder…
- Trial name
- NCT00050804
- Testing
- sertraline
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Cirrhosis, PTSD
Microbiome Modulation With Prebiotics in PTSD and Cirrhosis
Despite medical advancements, PTSD remains a major issue in Veterans1. Current treatment strategies have relatively poor adherence.
- Trial name
- RESIST-PTSD (NCT06464952)
- Testing
- Resistant potato starch, Powdered cellulose
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
PTSD, Depression, Anxiety
Physical Activity Intervention for Trauma Afflicted Refugees
This study evaluates the effects of a 10-session physical activity intervention for trauma afflicted refugees. Half of participants will receive this 10-session physical activity intervention and half of the participants will be…
- Conditions
- PTSD, Depression, Anxiety, Physical Activity
- Trial name
- NCT04065126
- Testing
- Physical activity intervention, Brief psycho-education
- Where
- Sweden
- Volunteers
- 183 people
- Sponsor
- Swedish Red Cross University College