Clinical trials: Traumatic Amputation, open to volunteers
Amputation, Amputation; Traumatic, Hand
Evaluation of Myoelectric Implantable Recording Array (MIRA) in Participants With Transradial Amputation
The purpose of this research study is to see how well a new type of myoelectric prosthesis works. A myoelectric prosthesis is a robotic limb for amputees that is controlled by sensing the activity of muscles in the body above the…
- Trial name
- MIRA (NCT05768802)
- Testing
- Myoelectric Implantable Recording Array (MIRA)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Boninger, Michael, MD
Amputation, Traumatic, Pain, Phantom
Feasibility of Using an App for Managing Phantom Limb Pain Associated with Combat Injury in Ukraine (PAMELA)
In Ukraine, since the beginning of the full-scale war on February 24, 2022, a large number of individuals have lost a limb(s). Many of these amputees cannot access appropriate care in terms of pain management and rehabilitation.
- Conditions
- Amputation, Traumatic, Pain, Phantom, Pain, Acute, Pain, Chronic
- Trial name
- PAMELA (NCT06604507)
- Testing
- non-pharmacological app
- Where
- 5 sites in Ukraine
- Volunteers
- 200 people
- Sponsor
- Winfried Meißner
Amputation, Amputation, Traumatic
Understanding How Powered Componentry Impacts K2-Level Transfemoral Amputee Gait
The goal of this study is to understand how providing power at the knee or ankle individually, or providing power at both the knee and ankle, impacts ambulation for K2 level transfemoral amputees.
- Conditions
- Amputation, Amputation, Traumatic, Amputation of Knee, Amputation; Traumatic, Limb
- Trial name
- NCT06433648
- Testing
- Ottobock CLeg4 + Ottobock foot, SRALAB Hybrid Knee + Polycentric Ankle, SRALAB Hybrid Knee + Passive Ankle
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Shirley Ryan AbilityLab
VTE (Venous Thromboembolism), Phantom Limb Pain After Amputation
Venous Thromboembolism and Chronic Pain After Major Limb Trauma
Major limb trauma is associated with a high risk of venous thromboembolism (VTE) due to systemic inflammation, endothelial injury, immobilization, and hypercoagulability.
- Conditions
- VTE (Venous Thromboembolism), Phantom Limb Pain After Amputation, Chronic Pain, Chronic Pain Due to Injury
- Trial name
- THROMBO-PAIN (NCT07475910)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Amputation of Lower Limb Below Knee, Amputation, Traumatic
REsistance and LOADing Exercise for Bone Health
Lower limb amputation, often resulting from military conflict and road traffic accidents, is associated with reduced hip bone mineral density (BMD) and increased risk of hip fractures.
- Conditions
- Amputation of Lower Limb Below Knee, Amputation, Traumatic, Amputation, Limb Loss
- Trial name
- RELOAD (NCT07817381)
- Testing
- Resistance and high-impact exercise training
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Defence Medical Rehabilitation Centre, UK
Amputation, Traumatic, Wounds and Injuries
Human Upper Extremity Allotransplantation
Background: Millions of people each year sustain injuries, have tumors surgically removed, or are born with defects that require complex reconstructive surgeries to repair.
- Conditions
- Amputation, Traumatic, Wounds and Injuries, Hand Injuries
- Trial name
- NCT01459107
- Testing
- Deceased donor hand transplantation, Bone marrow cell-based therapy & single-drug immunosuppression.
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Johns Hopkins University
Lower Limb Amputation Above Knee
Microenvironment in Patients Undergoing Non-traumatic Amputation
The microenvironment of the amputation stump in patients undergoing non-traumatic transfemoral amputation will be investigated with a combination of microdialysis and tissue sampling.
- Trial name
- MiAMII (NCT07384689)
- Testing
- ciNPWT, SSD
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Traumatic Injury, Burns
Pilot Feasibility Trial of a Peer Support Program for Trauma Survivors
Traumatic injuries from events like car crashes, falls, or fires are a leading cause of disability. Survivors often face not only physical challenges but also long-lasting pain, mental health challenges and difficulty returning…
- Conditions
- Traumatic Injury, Burns, Amputation, Mental Health Outcomes
- Trial name
- NCT07275892
- Testing
- Cross-continuum Peer Support Program
- Where
- 2 sites in Canada
- Volunteers
- 49 people
- Sponsor
- Sunnybrook Health Sciences Centre
Diabetic Foot, Pressure Ulcer
A Real-World Registry of Chronic Wounds and Ulcers
WOUNDJOURNEY is a longitudinal, real-world, observational registry designed to capture the full clinical course and patient journey associated with chronic wounds and ulcers.
- Conditions
- Diabetic Foot, Pressure Ulcer, Surgical Wound Dehiscence, Vasculitis
- Trial name
- WOUNDJOURNEY (NCT02280733)
- Testing
- Usual care
- Where
- United States
- Volunteers
- 300,000 people
- Sponsor
- U.S. Wound Registry
Amputation, Wounds and Injuries
Human Penile Allotransplantation
Injuries to the genitalia are of concern to the military with emphasis placed on the surgical reconstruction and psychological health of these Wounded Warriors.
- Conditions
- Amputation, Wounds and Injuries, Amputation, Traumatic, Urologic Surgical Procedures, Male
- Trial name
- NCT02395497
- Testing
- Monoclonal Antibody (Humanized Anti-CD52), Tacrolimus, Penile Allotransplantation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University
Amputation, PTSD
Evacuation Time and Tourniquet Use as Risk Factors for PTSD in Combat-Related Amputation
This study aims to evaluate the relationship between evacuation time, tourniquet use, and the development of post-traumatic stress disorder (PTSD) in patients with combat-related amputations.
- Conditions
- Amputation, PTSD, Combat Posttraumatic Stess Disorder, Combat Trauma
- Trial name
- EVAC-PTSD Stud (NCT07502313)
- Where
- Ukraine
- Volunteers
- 300 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Amputation, Amputation, Traumatic
Neuromusculoskeletal Interface for Bionic Arms
The overall objective of this proposal is to perform a first-in-human home trial of the Electronic Osseoanchored Prostheses for the Rehabilitation of Amputees (e-OPRA) implant system in individuals with transhumeral amputations…
- Conditions
- Amputation, Amputation, Traumatic, Amputation, Surgical, Upper Limb Amputation Above Elbow (Injury)
- Trial name
- NCT07032753
- Testing
- eOPRA, OPRA, eOPRA with sensory feedback
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Shirley Ryan AbilityLab
Fingertips Traumatic Amputations, Finger Injuries
Operative Treatment vs Treatment With Semi-occlusive Dressing for Single Finger Amputations
The goal of this interventional study is to find out whether conservative treatment with semi-occlusive film is superior to surgical treatment in single finger amputations in adult population.
- Conditions
- Fingertips Traumatic Amputations, Finger Injuries, Finger, Finger Injury
- Trial name
- FINACT (NCT07175675)
- Testing
- Operative treatment of surgeons choice, Semi-occlusive film
- Where
- Finland
- Volunteers
- 252 people
- Sponsor
- Tampere University Hospital