Clinical trials: Traumatic Brain Injury (TBI) Patients
Traumatic Brain Injury
Impact of v Release on Dysphagia in Patients With Traumatic Brain Injury
The goal of this clinical trial is to explore Clinical Effect of Myofascial Release Therapy in Dysphagic Traumatic Brain injured Survivors.
- Trial name
- NCT06328309
- Testing
- Rehabilitation treatment, Myofascial Release Therapy
- Volunteers
- 80 people
- Sponsor
- Copka Sonpashan
Brain Injuries, Traumatic, Brain Injury Traumatic Moderate
A Prospective Outcome Study in Patients With Moderate to Severe Traumatic Brain Injury
Traumatic brain injury (TBI) is the leading cause of death, disability and cognitive impairment in young people worldwide. The majority of the traumatic deaths in developed countries results directly from lesions in the central…
- Conditions
- Brain Injuries, Traumatic, Brain Injury Traumatic Moderate, Brain Injury Traumatic Severe
- Trial name
- TBI-PRO (NCT03810222)
- Testing
- N/A (Observational Study)
- Where
- Italy
- Volunteers
- 225 people
- Sponsor
- FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS
Traumatic Brain Injury, Subarachnoid Hemorrhage
Near Infrared Spectroscopy (NIRS) as Transfusion Indicator in Neurocritical Patients
Neurocritical ill patients are frequently transfused. Red blood cell transfusion (RBCT) in these patients has been associated with deleterious effects, including higher rates of nosocomial infections, multi-organ failure, and…
- Conditions
- Traumatic Brain Injury, Subarachnoid Hemorrhage, Intracerebral Hemorrhage
- Trial name
- NCT00566709
- Testing
- Red blood cells transfusion
- Where
- Spain
- Volunteers
- 102 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Stroke, Acute Traumatic Brain Injury
Clinimetric Application of FOUR Scale as in Treatment and Rehabilitation of Patients With Acute Cerebral Injury
The aim of this study is to increase the effectiveness of clinical monitoring of patients with acute cerebral insufficiency by improving the discriminative ability of the FOUR scale.
- Conditions
- Stroke, Acute Traumatic Brain Injury, Subarachnoid Hemorrhage
- Trial name
- FOURACI (NCT06043167)
- Testing
- The predictive value russian rendition the FOUR score.
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Surgut Clinical Trauma Hospital
Severe Traumatic Brain Injury With High Cerebral Pressure
Impact of Cardiac Blood Flow on Cerebral Blood Flow in Patients With Severe Traumatic Brain Injury
Severe traumatic brain injury with increased intracranial pressure can lead to decreased cerebral blood flow. Low cerebral blood flow is responsible for secondary lesions, leading to bad prognosis.
- Trial name
- DEBITC (NCT02019810)
- Testing
- Norepinephrine, Dobutamine and norepinephrine
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Grenoble
Stroke, Traumatic Brain Injury
Validation of an Obstacle Course Used in Patients With Muscle Tightness
This study is being conducted to compare healthy patients versus patients with muscle tightness in their leg(s) after an acquired brain injury using walking trials time, a balance test, and foot pressure data.
- Conditions
- Stroke, Traumatic Brain Injury, Multiple Sclerosis, Spasticity
- Trial name
- NCT00776048
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Traumatic Brain Injury
Effects of Transport on Patients With Traumatic Brain Injury
Hospitalized patients are often moved from their rooms to other hospital locations, particularly imaging facilities. For patients with traumatic brain injury, such movements may raise the risk of secondary brain injuries.
- Trial name
- NCT01077089
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Cincinnati
Traumatic Brain Injury (TBI) Patients, Neuroinflammation
Vitamin D3 for Moderate to Mild Traumatic Brain Injury: A Randomized Trial on Inflammation and Recovery (VIMOT)
This study is a Phase II, randomized, quadruple-blinded, placebo-controlled clinical trial designed to test whether vitamin D₃ supplementation can improve recovery after mild-to-moderate traumatic brain injury (TBI) in adults.
- Trial name
- VIMOT (NCT07269457)
- Testing
- Vitamin D3 (Cholecalciferol)
- Where
- Nigeria
- Volunteers
- 240 people
- Sponsor
- Lagos State University
TBI Traumatic Brain Injury
ESWT as a Treatment for Chronic NHO in TBI Patients
Effect of Extracorporeal Shock Wave Therapy on Chronic Neurogenic Heterotopic Ossification in Traumatic Brain Injured (TBI) patients Chronic Neurogenic Heterotopic Ossification (NHO) - Heterotopic ossification is a well known…
- Trial name
- NCT02331628
- Testing
- ESWT - Extracorporeal Shockwave Therapy
- Where
- Israel
- Volunteers
- 12 people
- Sponsor
- Loewenstein Hospital
Traumatic Brain Injury
Dexanabinol in Severe Traumatic Brain Injury
Each year a large number of patients are hospitalized at Shock Trauma Centers with severe head injuries. Bleeding into and swelling of these patients' brains may cause compression of vital structures, disability and death.
- Trial name
- NCT00129857
- Testing
- Dexanabinol
- Volunteers
- 860 people
- Sponsor
- Pharmos
Traumatic Brain Injury
Efficacy of Animal Assisted Therapy in the Treatment of Patients With Traumatic Brain Injury
Patients admitted to the ED with moderate to severe traumatic brain injury defined by GCS less than or equal to 10 and confirmed by head CT scan or MRI were randomized into 2 groups: one receiving animal assisted therapy (AAT)…
- Trial name
- AAT/TBI (NCT05217030)
- Testing
- Animal assisted therapy
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Inova Health Care Services
Traumatic Brain Injury
Different Feeding in Traumatic Brain Injury Patients
This was a multicenter randomized controlled study of 98 severe Traumatic Brain Injury patients with tracheostomy. Patients enrolled were divided randomly into the observation group with Intermittent Oro-esophageal Tube Feeding…
- Trial name
- NCT06249022
- Testing
- Rehabilitation therapy, Intermittent Oro-esophageal Tube Feeding, Nasogastric tube feeding
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Zeng Changhao
Neurologic Disorder, Traumatic Brain Injury
Effectiveness of Music Therapy on Level of Consciousness
It is known that even in patients with severe disorders of consciousness (DOC), the perception of known stimuli triggers emotional reactions that can be interpreted as an expression of a residual function of consciousness.
- Conditions
- Neurologic Disorder, Traumatic Brain Injury, Disorder of Consciousness
- Trial name
- NCT04442971
- Testing
- Music Stimulation, Alternative Stimulation, No Auditory Stimulation
- Where
- Germany
- Volunteers
- 66 people
- Sponsor
- BDH-Klinik Hessisch Oldendorf
Traumatic Brain Injury, Agitation,Psychomotor
Effects of Dexmedetomidine on Agitation in Critically Ill TBI Patients
Agitation is a frequent complication following traumatic braing injury in patients admitted to the intensive care unit. This agitation frequently results in the liberal use of rescue drugs such as antipsychotics, sedatives and…
- Trial name
- DEX-TBI (NCT06620393)
- Testing
- Dexmedetomidine
- Volunteers
- 72 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Tinnitus
Telephone Tinnitus Education for Patients With Traumatic Brain Injury (TBI)
This study continues the investigators' efforts to develop tinnitus management protocols for Veterans. More specifically, this study developed and evaluated an adaptation of Progressive Tinnitus Management (PTM) for use as a…
- Trial name
- NCT01129141
- Testing
- Tele-PTM, Wait List Control
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- VA Office of Research and Development
Concussion, Brain
Diffusion Tensor Brain MRI in the Detection of Structural Abnormality of the White Substance in Concussion
Concussions in sports are a major public health problem because of their frequency, and are often underdiagnosed because of an unspecific clinical picture or sometimes masked by the concussion itself.
- Trial name
- COMMOTION (NCT06144359)
- Testing
- specific MRI Acquisition (Diffusion Tensor Imaging) at 3T
- Where
- France
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Traumatic Brain Injury
Neurofeedback-enhanced Mindfulness Meditation in Traumatic Brain Injury
Spaulding Rehabilitation Hospital is conducting a research study evaluating the effectiveness of the brain-training product, MUSE, an EEG-guided neurofeedback device designed to assist in cultivating a relaxed, attentive state of…
- Trial name
- NCT02615535
- Testing
- EEG neurofeedback-assisted meditation, Non-EEG feedback-assisted meditation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Spaulding Rehabilitation Hospital
Traumatic Brain Injury, Coma
Optimized Therapy in Severe Traumatic Brain Injured Patients
Severe traumatic brain injury is associated with life-threatening and incapacitating secondary injury. Contemporary therapeutic interventions are aimed at preventing and treating secondary damage.
- Trial name
- NCT02130674
- Testing
- Dipeptiven
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- University of Zurich
Posttraumatic Stress Disorder, Traumatic Brain Injury
Cognitive REmediation After Trauma Exposure Trial = CREATE Trial
This study will evaluate the efficacy of methylphenidate and galantamine in the treatment of persistent cognitive symptoms associated with posttraumatic stress disorder (PTSD) and/or traumatic brain injury (TBI).
- Trial name
- CREATE (NCT01416948)
- Testing
- Methylphenidate Hydrochloride 20 mg, Galantamine 12 mg
- Where
- 7 sites in United States
- Volunteers
- 32 people
- Sponsor
- INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Traumatic Brain Injury, Ventilator Associated Pneumonia
Effect of E-BAL on Severity of VAP Assessed Through CPIS on the Patients of Traumatic Brain Injury in Neurocritical Care, Also Effect on Days of Ventilation and ICU Stay.
Severe traumatic brain injury (STBI) is a leading cause of disability, mortality, and economic burden worldwide. The impact of severe traumatic brain injury (STBI) on the economy of developing countries like Pakistan is…
- Trial name
- NCT04977843
- Testing
- EARLY BRONCHOALVEOLAR LAVAGE
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Jinnah Hospital